6173 results
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
Annals of cardiothoracic surgery,
Volume 12, Issue 4, 20 3 2023, Pages 350-357
Valve-sparing operations after Ross procedure: a single-center experience.
Jahanyar J, Arabkhani B, Zanella L, de Kerchove L, Tsai PI, Aphram G, Mastrobuoni S, El Khoury G
Background: The Ross procedure has demonstrated excellent long-term results, with restoration of life-expectancy in patients with severe aortic valve dysfunction. However, reintervention after Ross can occur, and herein we describe our center's experience with redo surgery after previous Ross procedures. Methods: We searched our prospective database for aortic valve-repair and recruited all adult (≥18 years) patients who have undergone valve-sparing root replacements (VSRRs) and/or aortic v...
Abstract
Cited 2 times since 2023 (1.1 per year)
source: EuropePMC
Journal of clinical medicine,
Volume 12, Issue 14, 20 3 2023, Pages 4798
Catheter-Based Techniques for Addressing Atrioventricular Valve Regurgitation in Adult Congenital Heart Disease Patients: A Descriptive Cohort.
El Bouziani A, Witte LS, Bouma BJ, Jongbloed MRM, Robbers-Visser D, Straver B, Beijk MAM, Kiès P, Koolbergen DR, van der Kley F, Schalij MJ, de Winter RJ, Egorova AD
Introduction: Increasing survival of adult congenital heart disease (ACHD) patients comes at the price of a range of late complications-arrhythmias, heart failure, and valvular dysfunction. Transcatheter valve interventions have become a legitimate alternative to conventional surgical treatment in selected acquired heart disease patients. However, literature on technical aspects, hemodynamic effects, and clinical outcomes of percutaneous atrioventricular (AV) valve interventions in ACHD patients...
Abstract
Pediatric emergency care,
Volume 39, Issue 9, 19 3 2023, Pages 661-665
Parental Attitudes About Lumbar Puncture in Children With Suspected Central Nervous System Infection.
Sahin A, Kara-Aksay A, Demir G, Ekemen-Keles Y, Ustundag G, Berksoy E, Karadag-Oncel E, Yilmaz D
Objectives: This study aimed to evaluate parents' attitudes toward lumbar puncture (LP) for their children with suspected central nervous system infection to determine the reasons for rejection and related factors. Methods: The survey was provided to parents of children (1 month to 18 years old) for whom LP was recommended because of a concern for central nervous system infection. Sociodemographic characteristics and other related factors of parents who did and did not approve of LP were co...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 9, Issue 8 Pt 3, 19 3 2023, Pages 1652-1664
Quantification of Large Transmural Biopsies Reveals Heterogeneity in Innervation Patterns in Chronic Myocardial Infarction.
Chen HS, Voortman LM, van Munsteren JC, Wisse LJ, Tofig BJ, Kristiansen SB, Glashan CA, DeRuiter MC, Zeppenfeld K, Jongbloed MRM
Background: Abnormal cardiac innervation plays an important role in arrhythmogenicity after myocardial infarction (MI). Data regarding reperfusion models and innervation abnormalities in the medium to long term after MI are sparse. Histologic quantification of the small-sized cardiac nerves is challenging, and transmural analysis has not been performed. Objectives: This study sought to assess cardiac innervation patterns in transmural biopsy sections in a porcine reperfusion model of MI (MI-R) u...
Abstract
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
BMC cardiovascular disorders,
Volume 23, Issue 1, 19 3 2023, Pages 363
Thoracic aortic atherosclerosis in patients with a bicuspid aortic valve; a case-control study.
Dolmaci OB, Klautz RJM, Poelmann RE, Lindeman JHN, Sprengers R, Kroft L, Grewal N
Introduction: Bicuspid aortic valve (BAV) patients have an increased risk to develop thoracic aortic complications. Little is known about the prevalence and severity of atherosclerosis in the BAV ascending aortic wall. This study evaluates and compares the prevalence of thoracic aortic atherosclerosis in BAV and tricuspid aortic valve (TAV) patients. Methods: Atherosclerosis was objectified using three diagnostic modalities in two separate BAV patient cohorts (with and without an aortic dilatati...
Abstract
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
Learning health systems,
Volume 8, Issue 1, 15 3 2023, Pages e10379
Learning healthcare systems in cardiology: A qualitative interview study on ethical dilemmas of a learning healthcare system.
Laurijssen S, van der Graaf R, Schuit E, den Haan M, van Dijk W, Groenwold R, le Sessie S, Grobbee D, de Vries M
Background: Implementation of an LHS in cardiology departments presents itself with ethical challenges, including ethical review and informed consent. In this qualitative study, we investigated stakeholders' attitudes toward ethical issues regarding the implementation of an LHS in the cardiology department. Methods: We conducted a qualitative study using 35 semi-structured interviews and 5 focus group interviews with 34 individuals. We interviewed cardiologists, research nurses, cardiovascu...
Abstract
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
Lung cancer (Amsterdam, Netherlands),
Volume 182, 11 2 2023, Pages 107294
Feasibility of salvage resection following locoregional failure after chemoradiotherapy and consolidation durvalumab for unresectable stage III non-small cell lung cancer.
Dickhoff C, Unal S, Heineman DJ, Winkelman JA, Braun J, Bahce I, van Dorp M, Senan S, Dahele M
Introduction: In patients with unresectable stage III non-small cell lung cancer, high-dose chemoradiotherapy (CRT) followed by consolidation durvalumab improves the 5-year overall survival compared to CRT alone. The feasibility and safety of salvage surgery for such patients who subsequently develop locoregional failure (LRF) is unclear. We evaluated our institutional experience with radical-intent salvage surgery in this patient population. Materials and methods: Details of patients undergoing...
Abstract
Cited 17 times since 2023 (9.5 per year)
source: EuropePMC
Acta neuropathologica communications,
Volume 11, Issue 1, 11 2 2023, Pages 112
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Riemenschneider H, Simonetti F, Sheth U, Katona E, Roth S, Hutten S, Farny D, Michaelsen M, Nuscher B, Schmidt MK, Flatley A, Schepers A, Gruijs da Silva LA, Zhou Q, Klopstock T, Liesz A, Arzberger T, Herms J, Feederle R, Gendron TF, Dormann D, Edbauer D
Cytoplasmic aggregation and concomitant nuclear clearance of the RNA-binding protein TDP-43 are found in ~ 90% of cases of amyotrophic lateral sclerosis and ~ 45% of patients living with frontotemporal lobar degeneration, but no disease-modifying therapy is available. Antibody therapy targeting other aggregating proteins associated with neurodegenerative disorders has shown beneficial effects in animal models and clinical trials. The most effective epitopes for safe antibody therapy targeting TD...
Abstract
Cited 4 times since 2023 (2.2 per year)
source: EuropePMC
Microbiology spectrum,
Volume 11, Issue 4, 11 2 2023, Pages e0502222
Metagenomic Surveillance of Viral Gastroenteritis in a Public Health Setting.
Schmitz D, Zwagemaker F, van der Veer B, Vennema H, Laros JFJ, Koopmans MPG, De Graaf M, Kroneman A
Norovirus is the primary cause of viral gastroenteritis (GE). To investigate norovirus epidemiology, there is a need for whole-genome sequencing and reference sets consisting of complete genomes. To investigate the potential of shotgun metagenomic sequencing on the Illumina platform for whole-genome sequencing, 71 reverse transcriptase quantitative PCR (RT-qPCR) norovirus positive-feces (threshold cycle [CT],
Abstract
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
Clinical epigenetics,
Volume 15, Issue 1, 6 1 2023, Pages 111
Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs.
Janssens K, Neefs I, Ibrahim J, Schepers A, Pauwels P, Peeters M, Van Camp G, Op de Beeck K
Background: Biomarker discovery in colorectal cancer has mostly focused on methylation patterns in normal and colorectal tumor tissue, but adenomas remain understudied. Therefore, we performed the first epigenome-wide study to profile methylation of all three tissue types combined and to identify discriminatory biomarkers. Results: Public methylation array data (Illumina EPIC and 450K) were collected from a total of 1 892 colorectal samples. Pairwise differential methylation analyses between tis...
Abstract
BMC ophthalmology,
Volume 23, Issue 1, 6 1 2023, Pages 301
Correction: Effect of alirocumab on cataracts in patients with acute coronary syndromes.
Suc G, Schwartz GG, Goodman SG, Jukema JW, Manvelian G, Poulouin Y, Pordy R, Scemama M, Szarek M, Steg PG, ODYSSEY OUTCOMES Investigators
Abstract
Cited 5 times since 2023 (2.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 202, 5 1 2023, Pages 30-40
Prognostic Relevance of Left Ventricular Global Longitudinal Strain in Patients With Heart Failure and Reduced Ejection Fraction.
Chimed S, Stassen J, Galloo X, Meucci MC, Knuuti J, Delgado V, van der Bijl P, Ajmone Marsan N, Bax JJ
Patients with heart failure (HF) and reduced ejection fraction (HFrEF) are complex patients who often have a high prevalence of co-morbidities and risk factors. In the present study, we investigated the prognostic significance of left ventricular (LV) global longitudinal strain (GLS) along with important clinical and echocardiographic variables in patients with HFrEF. Patients who had a first echocardiographic diagnosis of LV systolic dysfunction, defined as LV ejection fraction ≤45%, were selec...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
Frontiers in molecular biosciences,
Volume 10, 5 1 2023, Pages 1223972
Glycosaminoglycans and fucoidan have a protective effect on experimental glomerulonephritis.
Buijsers B, Maciej-Hulme M, Jacobs M, Bebber MB, de Graaf M, Salmenov R, Parr N, Rabelink TJ, Nijenhuis T, van der Vlag J
Background: The glomerular endothelial glycocalyx is degraded during inflammation. The glycocalyx plays a pivotal role in endothelial function and is involved in many processes including binding of chemokines and cytokines, leukocyte trafficking, and preventing proteinuria. HS-based therapeutics are a promising novel class of anti-inflammatory drugs to restore a compromised endothelial glycocalyx under inflammatory conditions. Recently, we demonstrated that treatment with HS extracted from unsti...
Abstract
Cited 4 times since 2023 (2.2 per year)
source: EuropePMC
JAMA network open,
Volume 6, Issue 7, 3 1 2023, Pages e2323112
Clinical Characteristics and Outcomes of Patients With Cutibacterium acnes Endocarditis.
Heinen FJ, Arregle F, van den Brink FS, Ajmone Marsan N, Bernts L, Houthuizen P, Kamp O, Roescher N, Timmermans N, Verkaik N, Roos-Hesselink J, Post MC, Habib G, Tanis W
Importance: It is suggested that patients with Cutibacterium acnes endocarditis often present without fever or abnormal inflammatory markers. However, no study has yet confirmed this statement. Objective: To assess the clinical characteristics and outcomes of patients with C acnes endocarditis. Design, setting, and participants: A case series of 105 patients presenting to 7 hospitals in the Netherlands and France (4 university hospitals and 3 teaching hospitals) with definite endocarditis accord...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
Seminars in radiation oncology,
Volume 33, Issue 3, 1 1 2023, Pages 243-251
Machine Learning & Molecular Radiation Tumor Biomarkers.
Rydzewski NR, Helzer KT, Bootsma M, Shi Y, Bakhtiar H, Sjöström M, Zhao SG
Developing radiation tumor biomarkers that can guide personalized radiotherapy clinical decision making is a critical goal in the effort towards precision cancer medicine. High-throughput molecular assays paired with modern computational techniques have the potential to identify individual tumor-specific signatures and create tools that can help understand heterogenous patient outcomes in response to radiotherapy, allowing clinicians to fully benefit from the technological advances in molecular...
Abstract
Cited 2 times since 2023 (1.1 per year)
source: EuropePMC
The British journal of surgery,
Volume 110, Issue 8, 1 1 2023, Pages 991-992
Future surgeon: bridging the intergenerational gap.
Huizing F, Sier VQ, Tresfon JAS, van der Vorst JR, Liem RSL, Schmitz RF, Schepers A, Houwert RM, Vriens MR, Snijders HS, Blok JJ
Abstract
Cited 12 times since 2023 (6.6 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 16, Issue 13, 1 1 2023, Pages 1612-1621
Evolution and Prognostic Impact of Right Ventricular-Pulmonary Artery Coupling After Transcatheter Aortic Valve Replacement.
Meucci MC, Malara S, Butcher SC, Hirasawa K, van der Kley F, Lombardo A, Aurigemma C, Romagnoli E, Trani C, Massetti M, Burzotta F, Bax JJ, Crea F, Ajmone Marsan N, Graziani F
Background: There is limited evidence regarding the association between right ventricular-to-pulmonary artery (RV-PA) coupling and outcomes after transcatheter aortic valve replacement (TAVR). Objectives: This study aimed to explore the evolution of RV-PA coupling in patients with severe aortic stenosis undergoing TAVR and its prognostic impact. Methods: A total of 900 patients who underwent TAVR in 2 tertiary centers and with echocardiographic analysis performed within 3 months before and after...
Abstract
Cited 10 times since 2023 (5.5 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 16, Issue 13, 1 1 2023, Pages 1682-1687
TAVR in Bicuspid Aortic Stenosis: Current Evidence and Proposal for a Randomized Controlled Trial Design.
Nuyens P, De Backer O, Sathananthan J, Højsgaard Jørgensen T, Treede H, Leipsic JA, Bax JJ, Webb JG, Mehran R, Chen M, Reardon M, Leon MB, Søndergaard L
Abstract
Cited 1 times since 2023 (0.6 per year)
source: EuropePMC
Nigerian journal of clinical practice,
Volume 26, Issue 7, 1 1 2023, Pages 992-997
Characteristics of maxillary sinus ostia and their correlation with anatomic variations of the osteomeatal complex: Indications for sinus floor elevation.
Eberlikose H, Yilmaz D, Gulen O
Background: Knowledge of the anatomy and variations of the maxillary sinus is essential for reducing oral surgery complications, such as sinus floor elevation, and increasing surgery success. The CBCT images of 385 patients were examined. Materials and methods: The prevalence, localization, and height of PMO (Primer Maxillary Ostium) and AMO (Accessory Maxillary Ostium) were evaluated with respect to sex, dentition, dental treatment, Schneiderian membrane (SM) thickness, concha bullosa, Haller C...
Abstract
Cited 8 times since 2023 (4.4 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 24, Issue 8, 1 1 2023, Pages e119-e197
Three-dimensional transoesophageal echocardiography: how to use and when to use-a clinical consensus statement from the European Association of Cardiovascular Imaging of the European Society of Cardiology.
Faletra FF, Agricola E, Flachskampf FA, Hahn R, Pepi M, Ajmone Marsan N, Wunderlich N, Elif Sade L, Donal E, Zamorano JL, Cosyns B, Vannan M, Edvardsen T, Berrebi A, Popescu BA, Lancellotti P, Lang R, Bäck M, Bertrand PB, Dweck M, Keenan N, Stankovic I
Three-dimensional transoesophageal echocardiography (3D TOE) has been rapidly developed in the last 15 years. Currently, 3D TOE is particularly useful as an additional imaging modality for the cardiac echocardiographers in the echo-lab, for cardiac interventionalists as a tool to guide complex catheter-based procedures cardiac, for surgeons to plan surgical strategies, and for cardiac anaesthesiologists and/or cardiologists, to assess intra-operative results. The authors of this document believe...
Abstract
