Research

Publications

Below you can find a list of our published research.

9618 results

Cited 43 times since 2010 (2.9 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 96, Issue 19, 1 1 2010, Pages 1593-1600 Amiodarone: an effective antiarrhythmic drug with unusual side effects. van Erven L, Schalij MJ

Abstract

Cited 66 times since 2010 (4.4 per year) source: EuropePMC

World journal of surgery, Volume 34, Issue 10, 1 1 2010, Pages 2278-2285 Routine ultrasound and limited computed tomography for the diagnosis of acute appendicitis. Toorenvliet BR, Wiersma F, Bakker RF, Merkus JW, Breslau PJ, Hamming JF

Background: Acute appendicitis continues to be a challenging diagnosis. Preoperative radiological imaging using ultrasound (US) or computed tomography (CT) has gained popularity as it may offer a more accurate diagnosis than classic clinical evaluation. The optimal implementation of these diagnostic modalities has yet to be established. The aim of the present study was to investigate a diagnostic pathway that uses routine US, limited CT, and clinical re-evaluation for patients with acute appendi... Abstract

Cited 972 times since 2010 (65.3 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 12, Issue 10, 1 1 2010, Pages 1360-1420 Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH, ESC Committee for Practice Guidelines

Abstract

Cited 6 times since 2010 (0.4 per year) source: EuropePMC

The American journal of cardiology, Volume 106, Issue 8, 1 1 2010, Pages 1146-1151 Effect of cardiac resynchronization therapy in patients with New York Heart Association functional class IV heart failure. van Bommel RJ, van Rijnsoever E, Borleffs CJ, Delgado V, Marsan NA, Bertini M, Schalij MJ, Bax JJ

Cardiac resynchronization therapy (CRT) is considered a class I indication in treatment of patients with New York Heart Association (NYHA) functional class III and IV heart failure. However, only small numbers of patients in large clinical trials have been in NYHA functional class IV. Therefore, little is known about the effects of CRT in this group. Therefore, we evaluated the effects of CRT in patients with NYHA functional class IV heart failure. Of all patients referred for CRT implantation,... Abstract

Cited 13 times since 2010 (0.9 per year) source: EuropePMC

The American journal of cardiology, Volume 106, Issue 8, 1 1 2010, Pages 1163-8, 1168.e1-8 Sexuality in adult patients with congenital heart disease and their partners. Winter MM, Reisma C, Kedde H, Bouma BJ, Vis JC, Luijendijk P, de Witte P, Zwinderman AH, Vliegen HW, Pieper PG, van Dijk AP, Mulder BJ

Data on relational and sexuality issues in adult patients with congenital heart disease (CHD) are scarce. The present study aimed to evaluate relational and sexual behaviors, satisfaction, and functioning in a representative sample of patients with CHD and their partners. In addition, we aimed to evaluate the relation between sexuality parameters and quality of life. Relational and sexuality issues were assessed using a sexuality questionnaire in 133 patients (52% men, 37 ± 13 years old) with CH... Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 18, Issue 10, 1 1 2010, Pages 464-465 Coronary artery anomalies, detection by dual-source computed tomography angiography. Vliegen HW

Abstract

Cited 24 times since 2010 (1.6 per year) source: EuropePMC

American heart journal, Volume 160, Issue 4, 1 1 2010, Pages 737-743 Prevalence and characteristics of patients with clinical improvement but not significant left ventricular reverse remodeling after cardiac resynchronization therapy. Auger D, van Bommel RJ, Bertini M, Delgado V, Ng AC, Ewe SH, Shanks M, Marsan NA, Mooyaart EA, Witkowski T, Poldermans D, Schalij MJ, Bax JJ

Background: Although most patients who improve in clinical status after cardiac resynchronization therapy (CRT) also show a significant left ventricular (LV) reverse remodeling, some patients do not show echocardiographic improvement. The aim of the present study was to evaluate the degree of agreement between clinical and echocardiographic response to CRT in a large cohort of heart failure patients, and to evaluate the characteristics of patients with clinical response but without echocardiogra... Abstract

Cited 55 times since 2010 (3.7 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 56, Issue 18, 1 1 2010, Pages 1486-1492 Follow-up after pulmonary valve replacement in adults with tetralogy of Fallot: association between QRS duration and outcome. Scherptong RW, Hazekamp MG, Mulder BJ, Wijers O, Swenne CA, van der Wall EE, Schalij MJ, Vliegen HW

Objectives: The aim of this study was to analyze whether QRS duration, before and after pulmonary valve replacement (PVR), is related to long-term outcome in patients with tetralogy of Fallot (TOF). Background: Key factors that determine outcome after PVR in adult TOF patients are largely unknown. Recognition of such factors assists the identification of patients at increased risk of adverse events. Methods: Adults who previously underwent total correction for TOF (n=90; age 31.4±10.3 years) and... Abstract

Cited 14 times since 2010 (0.9 per year) source: EuropePMC

Current medical research and opinion, Volume 26, Issue 11, 29 5 2010, Pages 2589-2597 Lipid goals among patients with diabetes or metabolic syndrome: Lipid Treatment Assessment Project (L-TAP) 2. Jukema JW, Chiang CW, Ferrières J, Santos RD, Verdejo J, Waters DD, Messig M, Tarasenko L

Objective: This analysis of the Lipid Treatment Assessment Project 2 population compared lipid goal attainment by diabetes and metabolic syndrome status. Research design and methods: Dyslipidaemic patients aged ≥ 20 years on stable lipid lowering therapy had their lipid levels determined once during enrolment at investigation sites in nine countries between September 2006 and April 2007. Achievement of low-density lipoprotein (LDL) cholesterol success, triglycerides < 150 mg/dl (1.7 mmol/l),... Abstract

Cited 69 times since 2010 (4.6 per year) source: EuropePMC

PLoS computational biology, Volume 6, Issue 9, 23 4 2010, Pages e1000943 Literature mining for the discovery of hidden connections between drugs, genes and diseases. Frijters R, van Vugt M, Smeets R, van Schaik R, de Vlieg J, Alkema W

The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use in knowledge retrieval, the co-occurrence method is also well-suited to discover new, hidden relationships between biomedical concepts following a simple ABC-principle, in which A and C have no direc... Abstract

Cited 133 times since 2010 (8.9 per year) source: EuropePMC

European heart journal, Volume 32, Issue 1, 23 4 2010, Pages 104-114 Head-to-head comparison of contrast-enhanced magnetic resonance imaging and electroanatomical voltage mapping to assess post-infarct scar characteristics in patients with ventricular tachycardias: real-time image integration and reversed registration. Wijnmaalen AP, van der Geest RJ, van Huls van Taxis CF, Siebelink HM, Kroft LJ, Bax JJ, Reiber JH, Schalij MJ, Zeppenfeld K

Aims: Substrate-based ablation of ventricular tachycardia (VT) relies on electroanatomical voltage mapping (EAVM). Integration of scar information from contrast-enhanced magnetic resonance imaging (CE-MRI) with EAVM may provide supplementary information. This study assessed the relation between electrogram voltages and CE-MRI scar characteristics using real-time integration and reversed registration. Methods and results: Fifteen patients without implantable cardiac defibrillator (14 males, 64 ±... Abstract

Cited 27 times since 2010 (1.8 per year) source: EuropePMC

European heart journal, Volume 31, Issue 24, 23 4 2010, Pages 3054-3062 Association of intraventricular mechanical dyssynchrony with response to cardiac resynchronization therapy in heart failure patients with a narrow QRS complex. van Bommel RJ, Tanaka H, Delgado V, Bertini M, Borleffs CJ, Ajmone Marsan N, Holzmeister J, Ruschitzka F, Schalij MJ, Bax JJ, Gorcsan J

Aims: current criteria for cardiac resynchronization therapy (CRT) are restricted to patients with a wide QRS complex (>120 ms). Overall, only 30% of heart failure patients demonstrate a wide QRS complex, leaving the majority of heart failure patients without this treatment option. However, patients with a narrow QRS complex exhibit left ventricular (LV) mechanical dyssynchrony, as assessed with echocardiography. To further elucidate the possible beneficial effect of CRT in heart failure pati... Abstract

Cited 105 times since 2010 (7 per year) source: EuropePMC

Neurology, Volume 75, Issue 16, 22 4 2010, Pages 1439-1447 Pain in Guillain-Barre syndrome: a long-term follow-up study. Ruts L, Drenthen J, Jongen JL, Hop WC, Visser GH, Jacobs BC, van Doorn PA, Dutch GBS Study Group

Background: Pain in Guillain-Barré syndrome (GBS) may be pronounced and is often overlooked. Objectives: To obtain detailed information about pain in GBS and its clinical variants. Methods: This was a prospective cohort study in 156 patients with GBS (including 18 patients with Miller Fisher syndrome [MFS]). We assessed the location, type, and intensity of pain using questionnaires at standard time points during a 1-year follow-up. Pain data were compared to other clinical features and serology.... Abstract

Cited 52 times since 2010 (3.5 per year) source: EuropePMC

Journal of the Royal Society, Interface, Volume 8, Issue 57, 22 4 2010, Pages 578-584 The nosocomial transmission rate of animal-associated ST398 meticillin-resistant Staphylococcus aureus. Bootsma MC, Wassenberg MW, Trapman P, Bonten MJ

The global epidemiology of meticillin-resistant Staphylococcus aureus (MRSA) is characterized by different clonal lineages with different epidemiological behaviour. There are pandemic hospital clones (hospital-associated (HA-)MRSA), clones mainly causing community-acquired infections (community-associated (CA-)MRSA, mainly USA300) and an animal-associated clone (ST398) emerging in European and American livestock with subsequent spread to humans. Nosocomial transmission capacities (R(A)) of these... Abstract

Cited 9 times since 2010 (0.6 per year) source: EuropePMC

Journal of pharmaceutical and biomedical analysis, Volume 54, Issue 2, 21 3 2010, Pages 387-394 Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry. Loos WJ, de Graan AJ, de Bruijn P, van Schaik RH, van Fessem MA, Lam MH, Mathijssen RH, Wiemer EA

A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method has been developed and validated for the simultaneous quantitative determination of dextromethorphan (DM) and its metabolites dextrorphan (DX), 3-methoxymorphinan (3MM) and 3-hydroxymorphinan (3HM), in human lithium heparinized plasma. The extraction involved a simple liquid-liquid extraction with 1 ml n-butylchloride from 200μl aliquots of plasma, after the addition of 20 μl 4% (v/v) ammon... Abstract

Cited 15 times since 2010 (1 per year) source: EuropePMC

Aims: Left ventricular pacing site (LV-PS) was prospectively collected to test the influence of the anatomical LV-PS on the outcome of cardiac resynchronization therapy (CRT) and mortality. Methods and results: Four hundred and twenty-six patients with standard indications for CRT underwent echocardiographic and clinical evaluation before and after CRT implantation. The LV-PS was determined from fluoroscopy using the clockwise principle (CP). The LV-PS was categorized into three prospectively de... Abstract

Cited 19 times since 2010 (1.3 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 299, Issue 6, 17 3 2010, Pages H2037-45 The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction. Bongartz LG, Braam B, Verhaar MC, Cramer MJ, Goldschmeding R, Gaillard CA, Steendijk P, Doevendans PA, Joles JA

We recently developed a rat model of cardiorenal failure that is characterized by severe left ventricular systolic dysfunction (LVSD) and low nitric oxide (NO) production that persisted after temporary low-dose NO synthase inhibition. We hypothesized that LVSD was due to continued low NO availability and might be reversed by supplementing NO. Rats underwent a subtotal nephrectomy and were treated with low-dose NO synthase inhibition with N(ω)-nitro-l-arginine up to week 8. After 3 wk of washout,... Abstract

Cited 17 times since 2010 (1.1 per year) source: EuropePMC

Veterinary microbiology, Volume 148, Issue 2-4, 16 3 2010, Pages 183-188 Mortality attributable to bluetongue virus serotype 8 infection in Dutch dairy cows. Santman-Berends IM, van Schaik G, Bartels CJ, Stegeman JA, Vellema P

In 2007, bluetongue virus serotype 8 (BTV-8) re-emerged in the Netherlands and a large number of farmers notified morbidity and mortality associated with BTV-8 to the authorities. All dead cows in the Netherlands are registered in one of the three age classes: newborn calves 1 year. These registrations result in a complete data set of dead cattle per herd per day from 2003 until 2007. In this study, the mortality associated with BTV-8 for the Dutch dairy industry was estimated, based on this cen... Abstract

Cited 15 times since 2010 (1 per year) source: EuropePMC

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 39, Issue 4, 16 3 2010, Pages 490-494 Risk stratification for adult congenital heart surgery. van Gameren M, Putman LM, Takkenberg JJ, Bogers AJ

Objective: At this moment, no risk stratification models are available for adult congenital cardiac surgery. This study aims to identify a suitable stratification tool for the adult congenital heart surgery population. Pediatric congenital cardiac surgery score models were therefore tested in an adult congenital population. In addition, an age component was added to these models and performance was compared with the original score systems. Methods: The Risk Adjustment in Congenital Heart Surgery... Abstract

Cited 134 times since 2010 (9 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 141, Issue 6, 15 3 2010, Pages 1431-1439 Tricuspid annuloplasty prevents right ventricular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair. Van de Veire NR, Braun J, Delgado V, Versteegh MI, Dion RA, Klautz RJ, Bax JJ

Objectives: We hypothesize that concomitant tricuspid annuloplasty in patients with tricuspid annular dilatation who undergo mitral valve repair could prevent progression of tricuspid regurgitation and right ventricular remodeling. Methods: In 2002, 80 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performed in 13 patients with grade 3 or 4 tricuspid regurgitation. In 2004, 102 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performe... Abstract