6173 results
Cited 1 times since 2022 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 30, Issue 1, 20 3 2022, Pages 251-253
Using a deep learning algorithm to score coronary artery calcium in myocardial perfusion imaging: A real opportunity or just a new hype?
Stassen J, van der Bijl P, Bax JJ
Abstract
Cited 28 times since 2022 (9.8 per year)
source: EuropePMC
Science (New York, N.Y.),
Volume 376, Issue 6599, 17 3 2022, Pages eabf9088
Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.
O'Neill AC, Uzbas F, Antognolli G, Merino F, Draganova K, Jäck A, Zhang S, Pedini G, Schessner JP, Cramer K, Schepers A, Metzger F, Esgleas M, Smialowski P, Guerrini R, Falk S, Feederle R, Freytag S, Wang Z, Bahlo M, Jungmann R, Bagni C, Borner GHH, Robertson SP, Hauck SM, Götz M
The centrosome provides an intracellular anchor for the cytoskeleton, regulating cell division, cell migration, and cilia formation. We used spatial proteomics to elucidate protein interaction networks at the centrosome of human induced pluripotent stem cell-derived neural stem cells (NSCs) and neurons. Centrosome-associated proteins were largely cell type-specific, with protein hubs involved in RNA dynamics. Analysis of neurodevelopmental disease cohorts identified a significant overrepresentat...
Abstract
Cited 27 times since 2022 (9.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 15, Issue 10, 15 3 2022, Pages 1760-1767
Association Between Changes in Perivascular Adipose Tissue Density and Plaque Progression.
Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Kitslaar PH, Reiber JHC, Stone PH, Samady H, Virmani R, Narula J, Berman DS, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Background: The association between the change in vessel inflammation, as quantified by perivascular adipose tissue (PVAT) density, and the progression of coronary atherosclerosis remains to be determined. Objectives: The purpose of this study was to explore the association between the change in PVAT density and the progression of total and compositional plaque volume (PV). Methods: Patients were selected from a prospective multinational registry. Patients who underwent serial coronary computed...
Abstract
Cited 11 times since 2022 (3.9 per year)
source: EuropePMC
International journal of cardiology,
Volume 363, 15 3 2022, Pages 87-93
Left atrioventricular coupling index in hypertrophic cardiomyopathy and risk of new-onset atrial fibrillation.
Meucci MC, Fortuni F, Galloo X, Bootsma M, Crea F, Bax JJ, Marsan NA, Delgado V
Backgrounds: This study aimed to investigate the association between left atrioventricular coupling index (LACI) and the occurrence of atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM). Methods: A total of 373 patients with HCM and no history of AF were evaluated by transthoracic echocardiography. LACI was defined by the ratio of left atrial (LA) end-diastolic volume divided by left ventricular (LV) end-diastolic volume. The cut-off value for LACI (≥40%) to identify LA-...
Abstract
Cited 3 times since 2022 (1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 177, 9 2 2022, Pages 90-99
Prognostic Implications of Change in Left Ventricular Ejection Fraction After Transcatheter Aortic Valve Implantation.
Kuneman JH, Butcher SC, Singh GK, Wang X, Hirasawa K, van der Kley F, Leon MB, Knuuti J, Pibarot P, Ajmone Marsan N, Delgado V, Bax JJ
Reduced left ventricular (LV) systolic function is associated with worse prognosis in patients with severe aortic stenosis (AS) treated with transcatheter aortic valve implantation (TAVI). We aimed to examine the changes in left ventricular ejection fraction (LVEF) after TAVI among patients with varying baseline LVEF. Moreover, variables associated with lack of LVEF improvement were identified and the association with long-term outcomes was investigated. A total of 560 patients (age 80 ± 7 years...
Abstract
Cited 20 times since 2022 (7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 177, 9 2 2022, Pages 151-161
Right Ventricular Myocardial Work Characterization in Patients With Pulmonary Hypertension and Relation to Invasive Hemodynamic Parameters and Outcomes.
Butcher SC, Feloukidis C, Kamperidis V, Yedidya I, Stassen J, Fortuni F, Vrana E, Mouratoglou SA, Boutou A, Giannakoulas G, Playford D, Ajmone Marsan N, Bax JJ, Delgado V
Noninvasive evaluation of indexes of right ventricular (RV) myocardial work (RVMW) derived from RV pressure-strain loops may provide novel insights into RV function in precapillary pulmonary hypertension. This study was designed to evaluate the association between the indexes of RVMW and invasive parameters of right heart catheterization and all-cause mortality. Noninvasive analysis of RVMW was completed in 51 patients (mean age 58.1 ± 12.7 years, 31% men) with group I or group IV pulmonary hype...
Abstract
Cited 4 times since 2022 (1.4 per year)
source: EuropePMC
Clinical cardiology,
Volume 45, Issue 8, 8 2 2022, Pages 873-881
Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease.
Won KB, Park HB, Heo R, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Gonçalves PA, Leipsic JA, Lee SE, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Berman DS, Narula J, Bax JJ, Min JK, Chang HJ
Background: Atherosclerosis-related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain ) with coronary plaque volume changes (PVC) has been limited in adults without traditional CV disease. Hypothesis: Normal SBPmaintain is important to attenuate coronary atherosclerosis progression in adults without baseline CV disease. Methods: We analyzed 95 adults (56...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
Structural heart : the journal of the Heart Team,
Volume 6, Issue 3, 8 2 2022, Pages 100042
Sex-Related Differences in Medically Treated Moderate Aortic Stenosis.
Stassen J, Pio SM, Ewe SH, Amanullah MR, Hirasawa K, Butcher SC, Singh GK, Sin KYK, Ding ZP, Chew NWS, Sia CH, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Background: Recent data showed poor long-term survival in patients with moderate AS. Although sex differences in left ventricular (LV) remodeling and outcome are well described in severe AS, it has not been evaluated in moderate AS. Methods: In this retrospective, multicenter study, patients with a first diagnosis of moderate AS diagnosed between 2001 and 2019 were identified. Clinical and echocardiographic parameters were recorded at baseline and compared between men and women. Patients were fo...
Abstract
Cited 26 times since 2022 (9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 7, 1 1 2022, Pages 885-897
The dysfunctional right ventricle: the importance of multi-modality imaging.
Surkova E, Cosyns B, Gerber B, Gimelli A, La Gerche A, Ajmone Marsan N
Assessment of right ventricular (RV) function is crucial for the evaluation of the dyspnoeic patient and/or with systemic venous congestion and provides powerful prognostic insights. It can be performed using different imaging modalities including standard and advanced echocardiographic techniques, cardiac magnetic resonance imaging, computed tomography, and radionuclide techniques, which should be used in a complementary fashion. Each modality has strengths and weaknesses based on which the cho...
Abstract
Cited 146 times since 2022 (50.5 per year)
source: EuropePMC
JAMA,
Volume 327, Issue 23, 1 1 2022, Pages 2296-2305
Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial.
Marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski E, Mansour M, Marchlinski F, Wilber D, Hindricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N, DECAAF II Investigators
Importance: Ablation of persistent atrial fibrillation (AF) remains a challenge. Left atrial fibrosis plays an important role in the pathophysiology of AF and has been associated with poor procedural outcomes. Objective: To investigate the efficacy and adverse events of targeting atrial fibrosis detected on magnetic resonance imaging (MRI) in reducing atrial arrhythmia recurrence in persistent AF. Design, setting, and participants: The Efficacy of Delayed Enhancement-MRI-Guided Fibrosis Ablation...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 6, 1 1 2022, Pages 765-766
Optimization of guideline-directed medical treatment to reduce secondary mitral regurgitation: treat the ventricle, not only the valve.
Stassen J, van der Bijl P, Bax JJ
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 34, Issue 6, 1 1 2022, Pages 990-998
Long-term follow-up of thoracoscopic ablation in long-standing persistent atrial fibrillation.
Harlaar N, Oudeman MA, Trines SA, de Ruiter GS, Mertens BJ, Khan M, Klautz RJM, Zeppenfeld K, Zeppenfeld K, Tjon A, Braun J, van Brakel TJ
Objectives: Catheter ablation of long-standing persistent atrial fibrillation (LSPAF) remains challenging, with suboptimal success rates obtained following multiple procedures. Thoracoscopic ablation has shown effective at creating transmural lesions around the pulmonary veins and box; however, long-term rhythm follow-up data are lacking. This study aims, for the first time, to assess the long-term outcomes of thoracoscopic pulmonary vein and box ablation in LSPAF. Methods: Rhythm follow-up cons...
Abstract
Cited 8 times since 2022 (2.8 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 6, 1 1 2022, Pages 730-740
Clinical implications of left atrial reverse remodelling after cardiac resynchronization therapy.
Stassen J, Galloo X, Chimed S, Hirasawa K, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Aims: Left atrial (LA) function is a marker of prognosis in patients with heart failure. The prognostic implications of an improvement in LA function in addition to an improvement in left ventricular (LV) function after cardiac resynchronization therapy (CRT) implantation are unknown. This study aimed to evaluate the prognostic value of a significant change in LA reservoir strain (RS) and/or LV global longitudinal strain (GLS) after initiation of CRT. Methods and results: LARS and LVGLS were mea...
Abstract
Cited 6 times since 2022 (2.1 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 6, 1 1 2022, Pages 781-789
Sex differences in left ventricular remodelling in patients with severe aortic valve stenosis.
Kuneman JH, Singh GK, Milhorini Pio S, Hirasawa K, Hautemann D, van der Kley F, Ajmone Marsan N, Knuuti J, Delgado V, Bax JJ
Aims: Women with severe aortic stenosis (AS) have better long-term outcome after transcatheter aortic valve implantation (TAVI) but worse survival after surgical aortic valve replacement compared with men. Whether this is related to sex differences in left ventricular (LV) remodelling is unknown. The aim of this study was to examine the sex differences in LV remodelling with multidetector row computed tomography (MDCT) and outcome in patients with severe AS undergoing TAVI between 2007 and 2018....
Abstract
Studies in health technology and informatics,
Volume 290, 1 1 2022, Pages 804-808
Expanding Access to CNS-TAP: Design, Development, and Initial Use of a Complex Precision Health Specialty Web App for Neuro-Oncology.
Ravi K, Meng G, Roberts HJ, Schepers A, Franson A, Koschmann C, Marini BL, Flynn A
This paper offers a case study to demonstrate how a complex scoring model tool called CNS-TAP, originally created by a neuro-oncology team at one institution, was upgraded and made accessible to a wider audience. In the Results and Discussion, many issues of web app design, development, and sustainability are covered. Overall, we chart a path to expand access to many unique software tools created and needed by today's medical specialists.
Abstract
Cited 9 times since 2022 (3.1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 62, Issue 1, 1 1 2022, Pages ezab478
Extracardiac conduit adequacy along the respiratory cycle in adolescent Fontan patients.
Rijnberg FM, van der Woude SFS, Hazekamp MG, van den Boogaard PJ, Lamb HJ, Terol Espinosa de Los Monteros C, Kroft LJM, Kenjeres S, Karim T, Jongbloed MRM, Westenberg JJM, Wentzel JJ, Roest AAW
Objectives: Adequacy of 16-20mm extracardiac conduits for adolescent Fontan patients remains unknown. This study aims to evaluate conduit adequacy using the inferior vena cava (IVC)-conduit velocity mismatch factor along the respiratory cycle. Methods: Real-time 2D flow MRI was prospectively acquired in 50 extracardiac (16-20mm conduits) Fontan patients (mean age 16.9 ± 4.5 years) at the subhepatic IVC, conduit and superior vena cava. Hepatic venous flow was determined by subtracting IVC flow fr...
Abstract
Cited 10 times since 2022 (3.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 6, 1 1 2022, Pages 790-799
Moderate aortic stenosis: importance of symptoms and left ventricular ejection fraction.
Stassen J, Ewe SH, Butcher SC, Amanullah MR, Hirasawa K, Singh GK, Sin KYK, Ding ZP, Pio SM, Sia CH, Chew NWS, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Delgado V, Bax JJ
Aims: The aim of this study is to investigate the independent determinants of survival in patients with moderate aortic stenosis (AS), stratified by severity of symptoms and left ventricular ejection fraction (LVEF). Methods and results: Patients with a first diagnosis of moderate AS (aortic valve area >1.0 and ≤1.5 cm2) were identified. Patients were stratified by New York Heart Association (NYHA) functional class (NYHA I, NYHA II, or NYHA III-IV) and LVEF (LVEF ≥60%, LVEF 50-59%, or LVEF...
Abstract
Cited 4 times since 2022 (1.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 11, 1 1 2022, Pages 503-509
Transcatheter aortic valve implantation amid the COVID-19 pandemic: a nationwide analysis of the first COVID-19 wave in the Netherlands.
Rooijakkers MJP, Li WWL, Stens NA, Vis MM, Tonino PAL, Timmers L, Van Mieghem NM, den Heijer P, Kats S, Stella PR, Roolvink V, van der Werf HW, Stoel MG, Schotborgh CE, Amoroso G, Porta F, van der Kley F, van Wely MH, Gehlmann H, van Garsse LAFM, Geuzebroek GSC, Verkroost MWA, Mourisse JM, Medendorp NM, van Royen N
Introduction: The coronavirus disease 2019 (COVID-19) pandemic has put tremendous pressure on healthcare systems. Most transcatheter aortic valve implantation (TAVI) centres have adopted different triage systems and procedural strategies to serve highest-risk patients first and to minimise the burden on hospital logistics and personnel. We therefore assessed the impact of the COVID-19 pandemic on patient selection, type of anaesthesia and outcomes after TAVI. Methods: We used data from the Nethe...
Abstract
Cited 6 times since 2022 (2.1 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 16, Issue 6, 31 5 2022, Pages 491-497
Age related compositional plaque burden by CT in patients with future ACS.
van Rosendael AR, van den Hoogen IJ, Lin FY, Gianni U, Lu Y, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, de Araújo Gonçalves P, Hadamitzky M, Kim YJ, Leipsic JA, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Cho I, Danad I, Gransar H, Budoff MJ, Samady H, Virmani R, Min JK, Narula J, Berman DS, Chang HJ, Shaw LJ, Bax JJ
Background: We examined age differences in whole-heart volumes of non-calcified and calcified atherosclerosis by coronary computed tomography angiography (CCTA) of patients with future ACS. Methods: A total of 234 patients with core-lab adjudicated ACS after baseline CCTA were enrolled. Atherosclerotic plaque was quantified and characterized from the main epicardial vessels and side branches on a 0.5 mm cross-sectional basis. Calcified plaque and non-calcified plaque were defined by above or be...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Artificial organs,
Volume 46, Issue 8, 31 5 2022, Pages 1709-1710
Unexpected negative results for CytoSorb during left ventricular assist device implantation: interpret with caution.
Papazisi O, Arabkhani B, Palmen M
Abstract
