Publications
Below you can find a list of our published research.
Op korte termijn komt deze Hart Long Centrum website te vervallen. Alle informatie kunt u vanaf heden vinden op https://www.lumc.nl/patientenzorg/specialistische-centra/hart-long-centrum/voor-patienten/
Below you can find a list of our published research.
6190 results
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 7 1 2024, Pages 15266028241301278 Ultrasound-Guided vs Non-Ultrasound-Guided Angio-Seal Vascular Hemosasis After Endovascular Treatment for Peripheral Artery Disease: An Observational Study. Groenewegen FA, Charehbili A, Panfilov IA, Engels C, De Jong WJ, Burgmans M, Van der Bogt KEA, Eefting D, Van der Steenhoven TJ, Van der Linden E, Urlings T
Clinical impact: Ultrasound visualization of vascular closure devices during endovascular access closure leads to a significant decrease in overall and major post interventional access site complications. This non-invasive and often readily available imaging technique could therefore lead to an important decrease in morbidity and subsequent overall health care costs when added to the standard intervention protocol. With the increasing use of endovascular techniques to treat peripheral artery dis... Abstract
Cited 1 times since 2024 (2.5 per year) source: EuropePMC
European journal of clinical investigation, Volume 55, Issue 3, 5 1 2024, Pages e14368 Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment. Theel WB, de Jong VD, Castro Cabezas M, Grobbee DE, Jukema JW, Trompet S
Background: Liver fibrosis progression is influenced by older age and cardiometabolic risk factors such as obesity and is associated with an increased risk of cardiovascular events. While statins may protect against cardiovascular complications, their effects in elderly individuals with obesity and liver fibrosis are unclear. Method: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) database was used to evaluate the effect of pravastatin on major adverse cardiovascular events... Abstract
Stem cell reports, Volume 20, Issue 1, 5 1 2024, Pages 102371 Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling. Yuan Q, Verbueken D, Dinani R, Kim R, Schoger E, Morsink CD, Simkooei SA, Kemna LJM, Hjortnaes J, Kuster DWD, Boon RA, Zelarayan LC, van der Velden J, Buikema JW
Embryonic signaling pathways exert stage-specific effects during cardiac development, yet the precise signals for proliferation or maturation remain elusive. To uncover the cues for proliferation, we performed a combinatory cell-cycle screen for insulin and glycogen synthase kinase-3 (GSK3) inhibition in spontaneously beating human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Our analysis for proliferation, and subsequential downstream sarcomere development, gene expression... Abstract
JTCVS open, Volume 23, 4 1 2024, Pages 69-80 Total aortic arch replacement versus proximal aortic repair for acute type a aortic dissection: A single-center 30-year experience. de Oliveira Marreiros DJ, Arabkhani B, Verhoef JL, Keekstra N, van der Vorst JR, van Schaik J, Braun J, Klautz RJM, Groenwold RHH, Hjortnaes J
Objective: Optimal surgical management of the aortic arch for acute type A aortic dissection remains contentious. We assessed clinical outcomes after total arch replacement and proximal aortic repair (ascending aortic ± hemiarch replacement) for acute type A aortic dissection. Methods: All patients surgically treated for acute type A aortic dissection at our institution between 1992 and 2021 were included. Study end points included all-cause mortality, distal aortic reintervention, stroke, and m... Abstract
European heart journal. Cardiovascular Imaging, Volume 26, Issue 1, 1 1 2024, Pages 173-174 Mural thickening of the coronary arteries in a COVID-19 patient. Groen RA, de Graaf MA, Stöger JL, van der Woude D, Antoni ML
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 26, Issue 12, 1 1 2024, Pages euae283 Ventricular septal defect characteristics influence presence of septal anatomical isthmuses in patients with repaired tetralogy of Fallot. Wallet J, Kimura Y, Blom NA, Hazekamp MG, Bartelings MM, Jongbloed MRM, Zeppenfeld K
Aims: In repaired tetralogy of Fallot (rTOF), the septal anatomical isthmuses (AI), AI 3, between the ventricular septal defect (VSD) and pulmonary annulus, and AI 4, between the VSD and tricuspid annulus, are important ventricular tachycardia (VT) substrates when slow conducting. Our aim was to assess the influence of VSD characteristics, specifically the presence of muscular or fibrous tissue at its border, on the presence or absence of septal AIs, potentially related to VT. Methods and result... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Current protocols, Volume 4, Issue 12, 1 1 2024, Pages e70068 Cryopreservation of Human Adult Ventricular Tissue for the Preparation of Viable Myocardial Slices. Lodrini AM, Groeneveld EJ, Palmen M, Hjortnaes J, Smits AM, Goumans MJ
Living myocardial slices (LMS) are ultrathin sections of adult myocardium that can be maintained in culture. These slices provide a unique platform for studying interactions between cardiomyocytes (CMs), other cardiac cell types, and the extracellular matrix while maintaining the cytoarchitecture and electrical phenotype of CMs over extended periods. Despite their advantages over other cardiac models, LMS have limitations, particularly their reliance on slice quality. The primary factor influenc... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 27, Issue 1, 1 1 2024, Pages euae300 Monitoring and modulating cardiac bioelectricity: from Einthoven to end-user. De Coster T, Nobacht A, Oostendorp T, de Vries AAF, Coronel R, Pijnappels DA
In 2024, we celebrate the 100th anniversary of Willem Einthoven receiving the Nobel Prize for his discovery of the mechanism of the electrocardiogram (ECG). Building on Einthoven's legacy, electrocardiography allows the monitoring of cardiac bioelectricity through solutions to the so-called forward and inverse problems. These solutions link local cardiac electrical signals with the morphology of the ECG, offering a reversible connection between the heart's electrical activity and its r... Abstract
Interdisciplinary cardiovascular and thoracic surgery, Volume 40, Issue 1, 1 1 2024, Pages ivae227 Examining the learning curves in robotic cardiac surgery wet lab simulation training. Atroshchenko GV, Navarra E, Valdis M, Sandoval E, Hashemi N, Cerny S, Pereda D, Palmen M, Bjerrum F, Bruun NH, Tolsgaard MG
Background: Simulation-based training has gained distinction in cardiothoracic surgery as robotic-assisted cardiac procedures evolve. Despite the increasing use of wet lab simulators, the effectiveness of these training methods and skill acquisition rates remain poorly understood. Objectives: This study aimed to compare learning curves and assess the robotic cardiac surgical skill acquisition rate for cardiac and noncardiac surgeons who had no robotic experience in a wet lab simulation setting.... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
The Journal of cardiovascular surgery, Volume 66, Issue 1, 29 5 2024, Pages 3-16 Hemodynamic considerations in arteriovenous vascular access modalities for hemodialysis. White NA, Xiao Z, De Winter EP, Li M, De Vries MR, Van Der Bogt KE, Rotmans JI
Arteriovenous fistulas and arteriovenous grafts are the most commonly used vascular access for hemodialysis in patients with end-stage chronic kidney disease. However, both methods face significant challenges due to the hemodynamic disturbances induced by the arteriovenous anastomosis. This causes changes in vascular structure and blood flow velocity near the anastomosis site after the fistula/graft surgery, and introduces abnormal wall shear stress and cyclic stretch. This leads to endothelial... Abstract
Cited 1 times since 2024 (2.4 per year) source: EuropePMC
Talanta, Volume 285, 29 5 2024, Pages 127293 Flexible 3D nanofiber-based SERS biosensor for detection of miRNA-223-3p in early Laryngeal Cancer diagnosis. Martino S, Yilmaz D, Tammaro C, Misso G, Esposito A, Falco M, Cossu AM, Lombardi A, Amler E, Divin R, Giannetti A, Scrima M, Dardano P, De Stefano L, Rea I, De Luca AC, Caraglia M
MicroRNAs (miRNAs) are small non-coding RNAs (18-22 nucleotides) that regulate gene expression and are associated with various diseases, including Laryngeal Cancer (LCa), which has a high mortality rate due to late diagnosis. Traditional methods for miRNA detection present several drawbacks (time-consuming steps, high cost and high false positive rate). Early-stage diagnosis and selective detection of miRNAs remain challenging. This study proposes a 3D flexible biosensor that combines nanofibers... Abstract
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Volume 44, Issue 2, 29 5 2024, Pages 333-342 Overview of Pediatric Respiratory Syncytial Virus (RSV) infections: has risk perception for RSV changed in children with comorbid conditions? Yilmaz D, Tasar S, Tuz AE, Eroz NA, Oncel EK, Aksay AK, Yilmaz N
Objective: Respiratory syncytial virus (RSV) is the primary etiology of lower respiratory tract infection in children. The fluctuating incidence of RSV, particularly in light of the COVID-19 pandemic, has shifted the spotlight onto preventive strategies. Our study aims to investigate both the risk factors and clinical symptoms of RSV. Materials and methods: From February 2015 to February 2023, samples were analyzed during all seasons to identify viral respiratory infections. RSV was identified i... Abstract
Cited 1 times since 2024 (2.3 per year) source: EuropePMC
Scientific reports, Volume 14, Issue 1, 26 4 2024, Pages 29256 Severe and post-COVID-19 are associated with high expression of vimentin and reduced expression of N-cadherin. Yilmaz E, Yilmaz D, Cacan E
SARS-CoV-2 penetrates human cells via its spike protein, which mainly interacts with ACE2 receptors, triggering viral replication and an exacerbated immune response characterized by a cytokine storm. Vimentin III, an intermediate filament protein predominantly found in mesenchymal cells, has garnered considerable attention in recent research due to its multifaceted biological roles and significance in the endothelial-mesenchymal transition (EndMT) during various fibrotic processes. However, the... Abstract
Cited 1 times since 2024 (2.3 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 105, Issue 2, 24 4 2024, Pages 385-393 Intravascular Lithotripsy in Acute Coronary Syndromes: Procedural and One-Year Clinical Outcomes From the BENELUX-IVL Registry. Oliveri F, van Oort MJH, Al Amri I, Bingen BO, Claessen BE, Dimitriu-Leen AC, Kefer J, Girgis H, Vossenberg T, van der Van der Kley F, Jukema JW, Montero-Cabezas JM
Background: Despite the excellent success and safety of intravascular lithotripsy (IVL) in heavily calcified lesions, evidence in acute coronary syndromes (ACS) remains limited. Aims: This study aimed to evaluate the procedural and clinical outcomes of IVL in heavily calcified ACS. Methods: Patients who underwent IVL between 2019 and 2024 from the ongoing prospective BENELUX registry were eligible for inclusion. Patients were therefore classified in ACS and chronic coronary syndrome (CCS) groups... Abstract
Annals of vascular surgery, Volume 111, 23 4 2024, Pages 203-211 A Diagnostic Comparison Study between Maximal Systolic Acceleration and Acceleration Time to Detect Peripheral Arterial Disease. Willems SA, van Bennekom OO, Schepers A, van Schaik J, van der Vorst JR, Hamming JF, Brouwers JJWM
Background: Detecting peripheral arterial disease (PAD) can be particularly challenging in patients with diabetes mellitus (DM) or chronic kidney disease (CKD) due to medial arterial calcification (MAC). Current bedside tests, such as the ankle-brachial index, are less accurate in these patient groups. The primary aim of this study is to evaluate the diagnostic accuracy of point-of-care duplex ultrasound parameters maximal systolic acceleration (ACCmax) and acceleration time (AT) to detect PAD,... Abstract
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Volume 134, Issue 2, 19 3 2024, Pages 223-230 Behavioral feeding problems and parenting stress in toddlers with food protein-induced allergic proctocolitis. Celik P, Yilmaz D, Yuksel F, Akpinar F, Karabag K, Uzun AK, Dibek Misirlioglu E
Background: Food protein-induced allergic proctocolitis (FPIAP) typically develops in infancy, a critical period for taste preference and feeding skill development. Eliminating culprit foods, along with limited food options and the child's distressing symptoms, can significantly impact the mothers' parenting roles. However, research on behavioral feeding problems and parenting stress in toddlers with FPIAP is lacking. Objective: To assess feeding behaviors and parenting stress levels i... Abstract
Annals of medicine and surgery (2012), Volume 87, Issue 3, 18 3 2024, Pages 1351-1359 The safety of indocyanine green in patients with advanced chronic kidney disease or kidney transplantation: a scoping review. Kruiswijk MW, Nguyen Dinh HL, Tange FP, Koning S, van den Hoven P, Peul RC, Rotmans JI, Huurman VAL, Alwayn IPJ, Hamming JF, Vahrmeijer AL, van der Vorst JR
Near-infrared fluorescence imaging with indocyanine green (ICG) is increasingly being used in the field of image-guided surgery. Although ICG is considered non-nephrotoxic in current literature, caution is advised for the use of ICG in patients with advanced chronic kidney disease (CKD), including kidney transplant recipients. Therefore, a scoping review was performed to assess the safety of ICG in patients with advanced CKD or a renal allograft. This scoping review was guided by the PRISMA-ScR... Abstract
International journal of cardiology, Volume 420, 15 3 2024, Pages 132712 Unilateral-access vs. bilateral-access in transfemoral transcatheter aortic valve replacement: A slim fit approach. Pereira AR, Al Jaff AAM, Montero-Cabezas J, de Weger A, Candura D, Jukema JW, Arslan F, Regeer MV, Ajmone Marsan N, van-der-Kley F
Background: Vascular complications remain prevalent on transfemoral transcatheter aortic valve replacement (TF-TAVR) with a significant proportion related to the secondary arterial access. We hypothesized that placing the second sheath ipsilateral and distal to the delivery sheath could reduce vascular complications with similar safety and efficacy. Objectives: Comparing vascular complications and clinical outcomes when placing the secondary arterial sheath in the ipsilateral (unilateral-access)... Abstract
Turkish journal of medical sciences, Volume 55, Issue 1, 13 2 2024, Pages 237-241 Inflammatory changes in the prepuce and clinical findings according to the stages of phimosis. Doğan G, Yilmaz D, Ipek H, Metin M, Kahraman H, Afşarlar ÇE
Background/aim: Circumcision refers to the surgical removal of all or part of the prepuce. Circumcision is commonly performed on males in childhood to prevent urinary tract infections and for religious reasons. This study was designed to investigate the inflammatory processes in the prepuce according to the degree of phimosis in patients who underwent circumcision. Materials and methods: We conducted a prospective study on 173 male children under the age of 18 who underwent circumcision between... Abstract
The American journal of cardiology, Volume 236, 12 2 2024, Pages 49-55 Sex Differences in a Real-World Registry Examining Coronary Lithotripsy for Calcified Lesions. van Oort MJH, Oliveri F, Ibtihal AA, Bingen BO, Claessen BEPM, Dimitriu-Leen AC, Vossenberg TN, Kefer J, Girgis H, van der Kley F, Jukema JW, Montero-Cabezas JM
Intravascular lithotripsy (IVL) has been established as a safe and effective treatment for coronary artery calcification (CAC). This study aimed to evaluate sex-related differences in the treatment with IVL in a real-world, all-comers international registry. Patients who underwent IVL between May 2019 and February 2024 were enrolled from the BENELUX-IVL registry. Patients were divided into men and women groups. Efficacy end points included device success (delivery of the IVL balloon across the t... Abstract