Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6143 results
Cited 12 times since 2011 (0.8 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 4, Issue 2, 5 1 2011, Pages 122-129 Intramyocardial bone marrow-derived mononuclear cell injection for chronic myocardial ischemia: the effect on diastolic function. van Ramshorst J, Antoni ML, Beeres SL, Roes SD, Delgado V, Rodrigo SF, de Roos A, Holman ER, Fibbe WE, Lamb HJ, Zwaginga JJ, Boersma E, van der Wall EE, Schalij MJ, Atsma DE, Bax JJ
Background: The present substudy of a recently published randomized trial aimed to investigate the effect of intramyocardial bone marrow cell injection on diastolic function in patients with chronic myocardial ischemia. Methods and results: In a total of 50 patients, diastolic function was evaluated before and 3 months after bone marrow cell injection using standard echocardiography and strain analysis. In addition, MRI-derived transmitral flow measurements were obtained in a subset of 36 patien... Abstract
Cited 58 times since 2011 (4.1 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 13, Issue 3, 5 1 2011, Pages 389-394 Long-term follow-up of primary and secondary prevention implantable cardioverter defibrillator patients. van Welsenes GH, van Rees JB, Borleffs CJ, Cannegieter SC, Bax JJ, van Erven L, Schalij MJ
Aims: The beneficial effects of implantable cardioverter defibrillators (ICDs) in primary and secondary prevention patients are well established. However, data on potential differences between both groups in mortality and ICD therapy rates during long-term follow-up are scarce. The aim of the study was to assess differences in mortality and ICD therapy between secondary and primary prevention ICD recipients. Methods and results: With the exception of patients with congenital monogenetic cardiac... Abstract
Cited 17 times since 2011 (1.2 per year) source: EuropePMC
Heart rhythm, Volume 8, Issue 5, 4 1 2011, Pages 665-671 Reversed polarity of bipolar electrograms for predicting a successful ablation site in focal idiopathic right ventricular outflow tract arrhythmias. van Huls van Taxis CF, Wijnmaalen AP, den Uijl DW, Gawrysiak M, Putter H, Schalij MJ, Zeppenfeld K
Background: Radiofrequency catheter ablation (RFCA) for idiopathic right ventricular outflow tract (RVOT) arrhythmias is typically guided by local activation time (LAT) mapping and unipolar electrogram morphology (QS configuration). However, LAT mapping is limited by the large variation among patients, and the area demonstrating a QS configuration of the unipolar electrogram may be larger than the focal source. Reversed polarity has been proposed as a criterion for guiding RFCA. Objective: The p... Abstract
Cited 11 times since 2011 (0.8 per year) source: EuropePMC
Current problems in cardiology, Volume 36, Issue 1, 1 1 2011, Pages 9-47 Multimodality imaging in diabetic heart disease. Ng AC, Delgado V, Djaberi R, Schuijf JD, Boogers MJ, Auger D, Bertini M, de Roos A, van der Meer RW, Lamb HJ, Bax JJ
Diabetic heart disease is currently defined as left ventricular dysfunction that occurs independently of coronary artery disease and hypertension. Its underlying etiology is likely to be multifactorial, acting synergistically together to cause myocardial dysfunction. Multimodality cardiac imaging, such as echocardiography, nuclear, computed tomography, and magnetic resonance imaging, can provide invaluable insight into different aspects of the disease process, from imaging at the cellular level... Abstract
Cited 55 times since 2011 (3.9 per year) source: EuropePMC
The American journal of cardiology, Volume 107, Issue 2, 1 1 2011, Pages 243-249 Effect of pulmonary vein anatomy and left atrial dimensions on outcome of circumferential radiofrequency catheter ablation for atrial fibrillation. den Uijl DW, Tops LF, Delgado V, Schuijf JD, Kroft LJ, de Roos A, Boersma E, Trines SA, Zeppenfeld K, Schalij MJ, Bax JJ
Multislice computed tomography (MSCT) is commonly acquired before radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) to plan and guide the procedure. MSCT allows accurate measurement of the left atrial (LA) and pulmonary vein (PV) dimensions and classification of the PV anatomy. The aim of the present study was to investigate the effect of LA dimensions, PV dimensions, and PV anatomy on the outcome of circumferential RFCA for AF. A total of 100 consecutive patients undergoing R... Abstract
Cited 24 times since 2011 (1.7 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 91, Issue 1, 1 1 2011, Pages 113-121 Three-dimensional echocardiography for the preoperative assessment of patients with left ventricular aneurysm. Marsan NA, Westenberg JJ, Roes SD, van Bommel RJ, Delgado V, van der Geest RJ, de Roos A, Klautz RJ, Reiber JC, Bax JJ
Background: Surgical ventricular reconstruction has been proposed as a treatment option in heart failure patients with left ventricular (LV) aneurysm. The feasibility of this procedure has some limitations, and extensive preoperative evaluation is necessary to give the correct indication. For this purpose, magnetic resonance imaging (MRI) is currently considered the gold standard, providing accurate quantification of LV shape, size, and global and regional function together with the assessment o... Abstract
Cited 105 times since 2011 (7.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 57, Issue 3, 1 1 2011, Pages 324-331 Left atrial strain predicts reverse remodeling after catheter ablation for atrial fibrillation. Tops LF, Delgado V, Bertini M, Marsan NA, Den Uijl DW, Trines SA, Zeppenfeld K, Holman E, Schalij MJ, Bax JJ
Objectives: The purpose of this study was to assess left atrial (LA) strain during long-term follow-up after catheter ablation for atrial fibrillation and to find predictors for LA reverse remodeling. Background: The association between LA reverse remodeling and improvement in LA strain after catheter ablation has not been investigated thus far. Methods: In 148 patients undergoing catheter ablation for atrial fibrillation, LA volumes and LA strain were assessed with echocardiography at baseline... Abstract
Cited 31 times since 2011 (2.2 per year) source: EuropePMC
American heart journal, Volume 161, Issue 1, 1 1 2011, Pages 197-203 Natriuretic peptide levels predict recurrence of atrial fibrillation after radiofrequency catheter ablation. den Uijl DW, Delgado V, Tops LF, Ng AC, Boersma E, Trines SA, Zeppenfeld K, Schalij MJ, van der Laarse A, Bax JJ
Background: the presence of atrial fibrillation (AF) is related to increased levels of natriuretic peptides. In addition, increased natriuretic peptide levels are predictive of the development of AF. However, the role of natriuretic peptides to predict recurrence of AF after radiofrequency catheter ablation (RFCA) is controversial. Objective: the study aimed to investigate the role of natriuretic peptides in the prediction of AF recurrence after RFCA for AF. Methods: pre-procedural amino-termina... Abstract
Cited 20 times since 2011 (1.4 per year) source: EuropePMC
International review of cell and molecular biology, Volume 290, 1 1 2011, Pages 87-119 Role for primary cilia as flow detectors in the cardiovascular system. Van der Heiden K, Egorova AD, Poelmann RE, Wentzel JJ, Hierck BP
The cardiovascular system is exposed to biochemical and biomechanical signals. Various sensors for these signals have been described and they contribute to cardiovascular development, maintenance of vessel integrity during adult life, and to pathogenesis. In the past 10years, primary cilia, membrane-covered, rod-like cellular protrusions, were discovered on multiple cell types of the cardiovascular system. Primary cilia are sensory organelles involved in several key (developmental) signaling pat... Abstract
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 57, Issue 4, 1 1 2011, Pages 480-514 Highlights of the year in JACC 2010. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Cardiology journal, Volume 18, Issue 3, 1 1 2011, Pages 289-296 Interventional creation of an atrial septal defect and its impact on right ventricular function: an animal study with the pressure-volume conductance system. Uebing A, Fischer G, Schlangen J, Hansen T, Grabitz RG, Becker K, Steendijk P, Kramer HH
Background: The aim of our study was to assess the suitability of different interventional techniques to create an atrial septal defect (ASD) and to evaluate the short-term effects of right ventricular (RV) volume overload on RV contractility in the growing swine. Methods: Thirteen ASD and six control animals were studied. An ASD was created by balloon dilatation (BD) of the fossa ovalis (n = 4) or by implantation of a multi-perforated Amplatzer Septal Occluder (n = 4) or a patch-less nitinol de... Abstract
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Nederlands tijdschrift voor geneeskunde, Volume 155, 1 1 2011, Pages A3158 [Summary of the practice guideline 'Venous leg ulcer' from the Dutch College of General Practitioners]. van Rijn-van Kortenhof NM, Wiersma T, van Hof N, Balak FS, Goudswaard LA
The practice guideline 'Venous leg ulcer' from the Dutch College of General Practitioners provides recommendations for the diagnosis and treatment of venous leg ulcer by the general practitioner. When counseling the patient it is important to make clear that the healing process can take a long time. Compression therapy remains the most important treatment for venous leg ulcer; it also reduces recurrence rates. The choice of wound dressing is dependent on the wound phase, the degree of... Abstract
Cited 6 times since 2011 (0.4 per year) source: EuropePMC
Disease markers, Volume 30, Issue 5, 1 1 2011, Pages 245-252 Asymmetric dimethylarginine (ADMA) levels display a morning peak in patients with acute myocardial infarction. Bergheanu SC, van der Laarse A, van der Bom JG, van der Hoeven BL, le Cessie S, de Jong MG, Liem SS, Schalij MJ, Jukema JW
High Asymmetric Dimethylarginine (ADMA) levels are associated with increased platelet activity, elevated blood pressure, vasoconstriction and impaired vascular relaxation. We hypothesized that the myocardial infarction morning peak of occurrence is closely related to a morning peak of ADMA levels. We performed a cross-sectional study among patients with documented myocardial infarction who had been enrolled in the prospective MISSION! Intervention Study. In total, serum ADMA levels were measured... Abstract
Cited 52 times since 2011 (3.7 per year) source: EuropePMC
Current pharmaceutical design, Volume 17, Issue 19, 1 1 2011, Pages 1890-1910 Clinical applications of the urokinase receptor (uPAR) for cancer patients. Boonstra MC, Verspaget HW, Ganesh S, Kubben FJ, Vahrmeijer AL, van de Velde CJ, Kuppen PJ, Quax PH, Sier CF
Since decades the urokinase plasminogen activator (uPA) system has been associated with the invasion of malignant cells. The receptor of urokinase (uPAR) is one of the key players in this proteolytic cascade, because it focuses uPA's proteolytic activity to the cell surface and in addition functions as a signaling receptor. uPAR is highly expressed in virtually all human cancers, suggesting possible clinical applications as diagnostic marker, predictive tool of survival or clinical response... Abstract
Cited 12 times since 2010 (0.8 per year) source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 41, Issue 3, 30 5 2011, Pages 418-428 T-cell-pre-stimulated monocytes promote neovascularisation in a murine hind limb ischaemia model. Hellingman AA, Zwaginga JJ, van Beem RT, TeRM/Smart Mix Consortium, Hamming JF, Fibbe WE, Quax PH, Geutskens SB
Aim: Monocytes play a significant role in neovascularisation. The stimuli that differentiate monocytes along a pro-angio-/arteriogenic-supporting pathway are currently unclear. We investigated whether pre-stimulation of human monocytes with soluble T-cell-derived factors improves revascularisation in murine hind limb ischaemia as a new option for therapeutic angio- and arteriogenesis. Design: Human monocytes were cultured with or without soluble T-cell-derived factors. Unstimulated and pre-stimu... Abstract
Cited 9 times since 2010 (0.6 per year) source: EuropePMC
Foot (Edinburgh, Scotland), Volume 21, Issue 3, 23 4 2010, Pages 124-128 Foot and ankle fractures at the supination line. Schepers T, van Schie-van der Weert EM, de Vries MR, van der Elst M
Background: The supination line is a fictive line along the foot and ankle, on which over twenty fracture types and approximately ten different ligamentous sprain-injuries have been identified. Objective: The current study was conducted to evaluate the incidence of different types of supination line injuries visible at the initial radiographs at the Emergency Department and to determine the type and percentage of misdiagnosed injuries. Method: Retrospective study of consecutive patients who visi... Abstract
Cited 18 times since 2010 (1.3 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 19, Issue 1, 22 4 2010, Pages 24-30 Improvements in 25 Years of Implantable Cardioverter Defibrillator Therapy. van Welsenes GH, Borleffs CJ, van Rees JB, Atary JZ, Thijssen J, van der Wall EE, Schalij MJ
In 1980, Dr. Michel Mirowski and his team inserted the first implantable cardioverter defibrillator (ICD) in a patient. Initially, ICD therapy was not widely accepted, and many physicians actually considered this therapy unethical. Large secondary and primary prevention trials, demonstrating a beneficial effect of ICD therapy in selected patients not only on arrhythmic death but also on all-cause mortality, stimulated a rapid growth in the number of implants and increased patient's and phys... Abstract
Cited 16 times since 2010 (1.1 per year) source: EuropePMC
The American journal of cardiology, Volume 107, Issue 4, 22 4 2010, Pages 609-614 Usefulness of repeated N-terminal pro-B-type natriuretic peptide measurements as incremental predictor for long-term cardiovascular outcome after vascular surgery. Goei D, van Kuijk JP, Flu WJ, Hoeks SE, Chonchol M, Verhagen HJ, Bax JJ, Poldermans D
Plasma N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) levels improve preoperative cardiac risk stratification in vascular surgery patients. However, single preoperative measurements of NT-pro-BNP cannot take into account the hemodynamic stress caused by anesthesia and surgery. Therefore, the aim of the present study was to assess the incremental predictive value of changes in NT-pro-BNP during the perioperative period for long-term cardiac mortality. Detailed cardiac histories, rest left... Abstract
Cited 7 times since 2010 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 107, Issue 5, 22 4 2010, Pages 736-740 Value of the surface electrocardiogram in detecting right ventricular dilatation in the presence of left bundle branch block. Van Bommel RJ, Marsan NA, Delgado V, van Rijnsoever EP, Schalij MJ, Bax JJ, Wellens HJ
Approximately 20% of patients with heart failure have left bundle branch block (LBBB) on surface electrocardiogram (ECG). In this group of patients, detection of right ventricular (RV) dilatation on standard ECG can be of clinical relevance because RV enlargement is an important prognostic marker. Consequently, the aim of this study was to evaluate diagnostic accuracy for several electrocardiographic criteria in determining significant RV dilatation in these patients. Standard 12-lead ECGs were... Abstract
Cited 170 times since 2010 (11.9 per year) source: EuropePMC
Circulation, Volume 123, Issue 1, 20 3 2010, Pages 70-78 Relative merits of left ventricular dyssynchrony, left ventricular lead position, and myocardial scar to predict long-term survival of ischemic heart failure patients undergoing cardiac resynchronization therapy. Delgado V, van Bommel RJ, Bertini M, Borleffs CJ, Marsan NA, Arnold CT, Nucifora G, van de Veire NR, Ypenburg C, Boersma E, Holman ER, Schalij MJ, Bax JJ
Background: The relative merits of left ventricular (LV) dyssynchrony, LV lead position, and myocardial scar to predict long-term outcome after cardiac resynchronization therapy remain unknown and were evaluated in the present study. Methods and results: In 397 ischemic heart failure patients, 2-dimensional speckle tracking imaging was performed, with comprehensive assessment of LV radial dyssynchrony, identification of the segment with latest mechanical activation, and detection of myocardial s... Abstract