6173 results
JVS-vascular science,
Volume 5, 1 1 2024, Pages 100210
Basic Vascular Science 2024 Meeting.
Sluiter TJ, Cruddas L, Ninno F, Schmitz-Rixen T, Tsui J, de Vries MR
The Basic Vascular Science (BVS) meeting was set up to provide a forum for researchers and clinicians in the field to exchange knowledge and ideas and to foster cross-disciplinary collaborations. The BVS 2024 meeting was held in Berlin. Attended by vascular surgeons and physicians, interventional radiologists, basic science researchers, and engineers, the meeting continues to successfully attract both early career researchers and established clinician-scientists. Here, we report on the scientifi...
Abstract
Cited 2 times since 2024 (2.3 per year)
source: EuropePMC
Diabetes care,
Volume 47, Issue 6, 1 1 2024, Pages 1042-1047
Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.
Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
Objective: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). Research design and methods: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. Results: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18.2%). We identified three novel genetic loc...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
JMIR human factors,
Volume 11, 31 5 2024, Pages e45055
Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study.
de Frel DL, Schroijen MA, Aardoom JJ, van Gils W, Huisman SD, Janssen VR, Versluis A, Kleinsmann MS, Atsma DE, Pijl H
Background: Type 2 diabetes (T2D) tremendously affects patient health and health care globally. Changing lifestyle behaviors can help curb the burden of T2D. However, health behavior change is a complex interplay of medical, behavioral, and psychological factors. Personalized lifestyle advice and promotion of self-management can help patients change their health behavior and improve glucose regulation. Digital tools are effective in areas of self-management and have great potential to support pa...
Abstract
JTCVS open,
Volume 20, 29 5 2024, Pages 210
Involving the next generation of cardiovascular surgeons.
Sier VQ, Blok JJ, Akca F, Hjortnaes J, van der Vorst JR
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
Chemistry (Weinheim an der Bergstrasse, Germany),
Volume 30, Issue 34, 24 4 2024, Pages e202400283
Understanding the Remarkable Stability of Well-Defined Dinuclear Copper(I) Carbene Complexes.
Bienenmann RLM, de Vries MR, Lutz M, Broere DLJ
The synthesis of a well-defined dicopper carbene complex supported by the PNNP (2,7-bis(di-tert-butylphosphaneyl)methyl-1,8-naphthyridine) expanded pincer ligand is reported. This carbene complex is remarkably stable, even in the presence of air and water. The reactivity of this complex was explored towards typical carbene transfer substrates and its electronic structure was investigated. Using a combination of experiments and DFT calculations, the principles that underly the stability of dinucl...
Abstract
Cited 6 times since 2024 (6.6 per year)
source: EuropePMC
JACC. Advances,
Volume 3, Issue 5, 22 4 2024, Pages 100959
Cardiac Damage Staging Predicts Outcomes in Aortic Valve Stenosis After Aortic Valve Replacement: Meta-Analysis.
Abdelfattah OM, Jacquemyn X, Sá MP, Jneid H, Sultan I, Cohen DJ, Gillam LD, Aron L, Clavel MA, Pibarot P, Bax JJ, Kapadia SR, Leon M, Généreux P
Background: The prognostic value of cardiac damage staging classification based on the extent of extravalvular damage has been proposed in moderate/severe aortic stenosis (AS). Objectives: The purpose of this study was to assess the association of cardiac damage staging with mortality across the spectrum of patients with AS following aortic surgical or transcatheter aortic valve replacement (AVR). Methods: We conducted a pooled meta-analysis of Kaplan-Meier-derived reconstructed time-to-event da...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
ESC heart failure,
Volume 11, Issue 5, 22 4 2024, Pages 2499-2509
In vivo fluid dynamics of the Ventura interatrial shunt device in patients with heart failure.
Pfeiffer M, Boehmer J, Gorcsan J, Eguchi S, Orihara Y, Perl ML, Eigler N, Abraham WT, Villota JN, Lee E, Bayés-Genís A, Moravsky G, Kar S, Zile MR, Holcomb R, Anker SD, Stone GW, Rodés-Cabau J, Lindenfeld J, Bax JJ
Aims: Interatrial shunts are under evaluation as a treatment for heart failure (HF); however, their in vivo flow performance has not been quantitatively studied. We aimed to investigate the fluid dynamics properties of the 0.51 cm orifice diameter Ventura shunt and assess its lumen integrity with serial transesophageal echocardiography (TEE). Methods and results: Computational fluid dynamics (CFD) and bench flow tests were used to establish the flow-pressure relationship of the shunt. Open-label...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 17, Issue 9, 22 4 2024, Pages 1015-1027
Left Atrial Improvement in Patients With Secondary Mitral Regurgitation and Heart Failure: The COAPT Trial.
Pio SM, Medvedofsky D, Delgado V, Stassen J, Weissman NJ, Grayburn PA, Kar S, Lim DS, Redfors B, Snyder C, Zhou Z, Alu MC, Kapadia SR, Lindenfeld J, Abraham WT, Mack MJ, Asch FM, Stone GW, Bax JJ, COAPT Trial Investigators
Background: Functional mitral regurgitation induces adverse effects on the left ventricle and the left atrium. Left atrial (LA) dilatation and reduced LA strain are associated with poor outcomes in heart failure (HF). Transcatheter edge-to-edge repair (TEER) of the mitral valve reduces heart failure hospitalization (HFH) and all-cause death in selected HF patients. Objectives: The aim of this study was to evaluate the impact of LA strain improvement 6 months after TEER on the outcomes of patient...
Abstract
Cited 10 times since 2024 (10.9 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 17, Issue 8, 22 4 2024, Pages 847-860
Diagnostic Value of Aortic Valve Calcification Levels in the Assessment of Low-Gradient Aortic Stenosis.
Adrichem R, Hokken TW, Bouwmeester S, Abdelkarim O, Vogel B, Blusztein DI, Veulemans V, Kuneman JH, Geleijnse ML, Verhemel S, Van den Dorpel MMP, Kardys I, Tonino PAL, Chang SM, Faza NN, Jou S, Ueyama HA, Bartkowiak J, Zeus T, Bax JJ, Bertrand PB, Hahn RT, Kodali SK, Lerakis S, Mehran R, Little SH, Houthuizen P, Van Mieghem NM
Background: In patients with low-gradient aortic stenosis (AS) and low transvalvular flow, dobutamine stress echocardiography (DSE) is recommended to determine AS severity, whereas the degree of aortic valve calcification (AVC) supposedly correlates with AS severity according to current European and American guidelines. Objectives: The purpose of this study was to assess the relationship between AVC and AS severity as determined using echocardiography and DSE in patients with aortic valve area
Abstract
Annals of cardiothoracic surgery,
Volume 13, Issue 3, 20 3 2024, Pages 244-254
Aortic root anatomy: insights into annular and root enlargement techniques.
Jahanyar J, Said SM, de Kerchove L, Lorenz V, de Beco G, Aphram G, Muñoz DE, Mastrobuoni S, Pettinari M, Arabkhani B, El Khoury G
The introduction of the Y(ang)-technique for aortic root enlargement has sparked a renewed interest in annular and root enlargement procedures world-wide. In order to execute these procedures proficiently however, it's important to understand the complex three-dimensional structure of the aortic root and left ventricular outflow tract, and also be familiar with the different enlargement techniques. Herein, we are providing a description of the aortic root anatomy and the most commonly utili...
Abstract
Cited 3 times since 2024 (3.3 per year)
source: EuropePMC
Nature ecology & evolution,
Volume 8, Issue 6, 20 3 2024, Pages 1118-1128
Directed conservation of the world's reef sharks and rays.
Goetze JS, Heithaus MR, MacNeil MA, Harvey E, Simpfendorfer CA, Heupel MR, Meekan M, Wilson S, Bond ME, Speed CW, Currey-Randall LM, Fisher R, Sherman CS, Kiszka JJ, Rees MJ, Udyawer V, Flowers KI, Clementi GM, Asher J, Beaufort O, Bernard ATF, Berumen ML, Bierwagen SL, Boslogo T, Brooks EJ, Brown JJ, Buddo D, Cáceres C, Casareto S, Charloo V, Cinner JE, Clua EEG, Cochran JEM, Cook N, D'Alberto BM, de Graaf M, Dornhege-Lazaroff MC, Fanovich L, Farabaugh NF, Fernando D, Ferreira CEL, Fields CYA, Flam AL, Floros C, Fourqurean V, Barcia LG, Garla R, Gastrich K, George L, Graham R, Hagan V, Hardenstine RS, Heck SM, Heithaus P, Henderson AC, Hertler H, Hueter RE, Johnson M, Jupiter SD, Kaimuddin M, Kasana D, Kelley M, Kessel ST, Kiilu B, Kyne F, Langlois T, Lawe J, Lédée EJI, Lindfield S, Maggs JQ, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Newman SJ, O'Shea OR, Osuka KE, Papastamatiou YP, Perera N, Peterson BJ, Pina-Amargós F, Ponzo A, Prasetyo A, Quam
Many shark populations are in decline around the world, with severe ecological and economic consequences. Fisheries management and marine protected areas (MPAs) have both been heralded as solutions. However, the effectiveness of MPAs alone is questionable, particularly for globally threatened sharks and rays ('elasmobranchs'), with little known about how fisheries management and MPAs interact to conserve these species. Here we use a dedicated global survey of coral reef elasmobranchs t...
Abstract
Cited 3 times since 2024 (3.2 per year)
source: EuropePMC
ESC heart failure,
Volume 11, Issue 5, 16 3 2024, Pages 2825-2834
Cardiac amyloidosis is not a single disease: a multiparametric comparison between the light chain and transthyretin forms.
Neculae G, Adam R, Jercan A, Bădeliță S, Tjahjadi C, Draghici M, Stan C, Bax JJ, Popescu BA, Marsan NA, Coriu D, Jurcuț R
Aims: Systemic amyloidosis represents a heterogeneous group of diseases resulting from amyloid fibre deposition. The purpose of this study is to establish a differential diagnosis algorithm targeted towards the two most frequent subtypes of CA. Methods and results: We prospectively included all consecutive patients with ATTR and AL evaluated between 2018 and 2022 in two centres in a score derivation cohort and a different validation sample. All patients had a complete clinical, biomarker, electr...
Abstract
Cited 7 times since 2024 (7.5 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 17, Issue 12, 16 3 2024, Pages 1485-1495
Prognostic Implications of Residual Tricuspid Regurgitation Grading After Transcatheter Tricuspid Valve Repair.
Dreyfus J, Taramasso M, Kresoja KP, Omran H, Iliadis C, Russo G, Weber M, Nombela-Franco L, Estevez Loureiro R, Hausleiter J, Latib A, Stolz L, Praz F, Windecker S, Zamorano JL, von Bardeleben RS, Tang GHL, Hahn R, Lubos E, Webb J, Schofer J, Fam N, Lauten A, Pedrazzini G, Rodés-Cabau J, Nejjari M, Badano L, Alessandrini H, Himbert D, Sievert H, Piayda K, Donal E, Modine T, Nickenig G, Pfister R, Rudolph V, Bernick J, Wells GA, Bax J, Lurz P, Enriquez-Sarano M, Maisano F, Messika-Zeitoun D, TRIGISTRY Investigators
Background: The safety profile of transcatheter tricuspid valve (TTV) repair techniques is well established, but residual tricuspid regurgitation (TR) remains a concern. Objectives: The authors sought to assess the impact of residual TR severity post-TTV repair on survival. Methods: We evaluated the survival rate at 2 years of 613 patients with severe isolated functional TR who underwent TTV repair in TRIGISTRY according to the severity of residual TR at discharge using a 3-grade (mild, moderate...
Abstract
Clinics (Sao Paulo, Brazil),
Volume 79, 16 3 2024, Pages 100382
The decline in postural balance has a negative impact on the performance of functional tasks in individuals with Parkinson's Disease.
Luna NMS, Bobbio TG, de Graaf M, Greve JMD, Ernandes RC, Dias AS, Lino MHDS, Soares-Junior JM, Baracat EC, Mochizuki L, Brech GC, Alonso AC
Introduction: An accurate assessment of balance problems is critical for decreasing the risk of falling in patients with Parkinson's Disease (PD). Reliable diagnostic tools such as Computerized Dynamic Posturography (CDP) are not feasible for the clinical setting. Therefore, the present study's aim was to assess the correlation between the clinical Balance Evaluation Systems Test (BESTest) and CDP. Methods: 20 male older adults with Parkinson's Disease (PD) were included in this s...
Abstract
Cited 6 times since 2024 (6.4 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 17, Issue 9, 15 3 2024, Pages 1062-1076
Artificial Intelligence-Enabled Quantitative Coronary Plaque and Hemodynamic Analysis for Predicting Acute Coronary Syndrome.
Koo BK, Yang S, Jung JW, Zhang J, Lee K, Hwang D, Lee KS, Doh JH, Nam CW, Kim TH, Shin ES, Chun EJ, Choi SY, Kim HK, Hong YJ, Park HJ, Kim SY, Husic M, Lambrechtsen J, Jensen JM, Nørgaard BL, Andreini D, Maurovich-Horvat P, Merkely B, Penicka M, de Bruyne B, Ihdayhid A, Ko B, Tzimas G, Leipsic J, Sanz J, Rabbat MG, Katchi F, Shah M, Tanaka N, Nakazato R, Asano T, Terashima M, Takashima H, Amano T, Sobue Y, Matsuo H, Otake H, Kubo T, Takahata M, Akasaka T, Kido T, Mochizuki T, Yokoi H, Okonogi T, Kawasaki T, Nakao K, Sakamoto T, Yonetsu T, Kakuta T, Yamauchi Y, Bax JJ, Shaw LJ, Stone PH, Narula J
Background: A lesion-level risk prediction for acute coronary syndrome (ACS) needs better characterization. Objectives: This study sought to investigate the additive value of artificial intelligence-enabled quantitative coronary plaque and hemodynamic analysis (AI-QCPHA). Methods: Among ACS patients who underwent coronary computed tomography angiography (CTA) from 1 month to 3 years before the ACS event, culprit and nonculprit lesions on coronary CTA were adjudicated based on invasive coronary a...
Abstract
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing,
Volume 67, Issue 7, 14 2 2024, Pages 1623-1634
Validation of a prediction model for early reconnection after cryoballoon ablation.
van Waaij K, Keçe F, de Riva M, Alizadeh Dehnavi R, Wijnmaalen AP, Piers SRD, Mertens BJ, Zeppenfeld K, Trines SA
Background: We previously developed an early reconnection/dormant conduction (ERC) prediction model for cryoballoon ablation to avoid a 30-min waiting period with adenosine infusion. We now aimed to validate this model based on time to isolation, number of unsuccessful cryo-applications, and nadir balloon temperature. Methods: Consecutive atrial fibrillation patients who underwent their first cryoballoon ablation in 2018-2019 at the Leiden University Medical Center were included. Model performan...
Abstract
Cited 3 times since 2024 (3.2 per year)
source: EuropePMC
Frontiers in immunology,
Volume 15, 13 2 2024, Pages 1327051
CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization.
Singh A, Kraaijeveld AO, Curaj A, Wichapong K, Hammerich L, de Jager SCA, Bot I, Atamas SP, van Berkel TJC, Jukema JW, Comerford I, McColl SR, Mees B, Heemskerk JWM, Nicolaes GAF, Hackeng T, Liehn EA, Tacke F, Biessen EAL
Introduction: The CC chemokine ligand 18 (CCL18) is a chemokine highly expressed in chronic inflammation in humans. Recent observations of elevated CCL18 plasma levels in patients with acute cardiovascular syndromes prompted an investigation into the role of CCL18 in the pathogenesis of human and mouse atherosclerosis. Methods and results: CCL18 was profoundly upregulated in ruptured human atherosclerotic plaque, particularly within macrophages. Repeated administration of CCL18 in Western-type d...
Abstract
The American journal of cardiology,
Volume 222, 8 2 2024, Pages 78-86
Significant Mitral Regurgitation After Permanent Right Ventricular Pacemaker Implantation: Prognostic Implications.
Nabeta T, Galloo X, Tops L, Stassen J, Marsan NA, van der Bijl P, Bax JJ
The underlying mechanisms leading to the development of mitral regurgitation (MR) after right ventricular (RV) pacemaker (PM) implantation and its prognostic value have yet to be fully understood. The purpose of this study was to evaluate the prevalence and clinical variables associated with the development of MR after RV pacing and its association with outcomes. A total of 451 patients (mean age 69 ± 15 years, 61% male) who underwent de novo RV PM implantation were included. The development of...
Abstract
Research and practice in thrombosis and haemostasis,
Volume 8, Issue 4, 6 1 2024, Pages 102437
Performance of risk scores in predicting major bleeding in left ventricular assist device recipients: a comparative external validation.
van der Horst SFB, de Jong Y, van Rein N, Jukema JW, Palmen M, Janssen E, Bonneville EF, Klok FA, Huisman MV, Tops LF, den Exter PL
Background: Implantation of a left ventricular assist device (LVAD) is a crucial therapeutic option for selected end-stage heart failure patients. However, major bleeding (MB) complications postimplantation are a significant concern. Objectives: We evaluated current risk scores' predictive accuracy for MB in LVAD recipients. Methods: We conducted an observational, single-center study of LVAD recipients (HeartWare or HeartMate-3, November 2010-December 2022) in the Netherlands. The primary o...
Abstract
Trials,
Volume 25, Issue 1, 6 1 2024, Pages 303
Refraining from closed reduction of displaced distal radius fractures in the emergency department-in short: the RECORDED trial.
Derksen BM, Jawahier PA, Wijers O, Knops SP, de Vries MR, van Hooff CCD, Verhofstad MHJ, Schep NWL
Background: With roughly 45,000 adult patients each year, distal radius fractures are one of the most common fractures in the emergency department. Approximately 60% of all these fractures are displaced and require surgery. The current guidelines advise to perform closed reduction of these fractures awaiting surgery, as it may lead to post-reduction pain relief and release tension of the surrounding neurovascular structures. Recent studies have shown that successful reduction does not warrant co...
Abstract
