Research

Publications

Below you can find a list of our published research.

6125 results

Cited 35 times since 2003 (1.6 per year) source: EuropePMC

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 60, Issue 4, 1 1 2003, Pages 452-457 Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the Venestent study. Hanekamp CE, Koolen JJ, Den Heijer P, Schalij MJ, Piek JJ, Bär FW, De Scheerder I, Bonnier HJ, Pijls NH, Venestent Study Group

The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vesse... Abstract

The international journal of cardiovascular imaging, Volume 19, Issue 6, 1 1 2003, Pages 549-552 MR imaging in arrhythmogenic right ventricular dysplasia/cardiomyopathy. van der Wall EE, Schalij MJ

Abstract

Cited 57 times since 2003 (2.7 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 126, Issue 6, 1 1 2003, Pages 2003-2010 Decellularization of rat aortic valve allografts reduces leaflet destruction and extracellular matrix remodeling. Grauss RW, Hazekamp MG, van Vliet S, Gittenberger-de Groot AC, DeRuiter MC

Objectives: Decellularization of aortic valve allografts in advance of transplantation is a promising approach to overcome immune-induced early graft failure. In this study the effects of in vitro cell extraction on extracellular matrix molecules and in vivo remodeling of decellularized aortic valves were investigated in a heterotopic aortic valve rat implantation model. Methods: Rat aortic valve conduits were decellularized by a 2-step detergent-enzymatic extraction method involving sodium dode... Abstract

Cited 27 times since 2003 (1.3 per year) source: EuropePMC

Journal of virology, Volume 77, Issue 24, 1 1 2003, Pages 12996-13004 Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity. Wieringa R, De Vries AA, Post SM, Rottier PJ

Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles... Abstract

Minerva cardioangiologica, Volume 51, Issue 6, 1 1 2003, Pages 667-676 Myocardial tissue Doppler echocardiography and cardiac resynchronization therapy. Molhoek SG, Schalij MJ, Van Der Wall EE, Bax JJ

Cardiac resynchronization therapy (CRT) is a promising technique for patients with end-stage, drug-refractory heart failure. Still 20-30% of the patients treated with CRT do not respond. Accordingly, the current selection criteria need to be refined, and it appears that demonstration of left ventricular dyssynchrony may be mandatory for response to CRT. Novel echocardiographic methods are currently investigated to detect left ventricular dyssynchrony and thereby improve the selection of candidat... Abstract

Cited 24 times since 2003 (1.1 per year) source: EuropePMC

The American journal of cardiology, Volume 92, Issue 11, 1 1 2003, Pages 1267-1270 Long-term prognosis after normal dobutamine stress echocardiography. Sozzi FB, Elhendy A, Roelandt JR, van Domburg RT, Schinkel AF, Vourvouri EC, Bax JJ, Rizzello V, Poldermans D

Patients with normal dobutamine stress echocardiography (DSE) were shown to have a favorable outcome at an intermediate-term follow-up. However, there are scarce data regarding long-term survival after normal DSE. This study sought to assess the long-term outcome after normal DSE. We studied 401 patients (age 62 +/- 10 years, 264 men) who had a normal echocardiogram at rest and with high-dose dobutamine stress. End points during a mean follow-up of 5 +/- 1.7 years (minimum 3.5) were all-cause mo... Abstract

Cited 4 times since 2003 (0.2 per year) source: EuropePMC

Pediatric nephrology (Berlin, Germany), Volume 19, Issue 2, 25 4 2003, Pages 237-239 Fulminant meningococcemia and acute renal failure in a 3-year-old boy. Akil I, Yüksel H, Coskun S, Yilmaz D, Onag A

Acute renal failure is a common occurrence in sepsis, but is rarely reported in meningococcemia. We present a young child diagnosed with fulminant meningococcemia who had several poor prognostic factors, including hypotension, thrombocytopenia, purpura fulminans, seizures, the absence of meningitis with meningococcemia, and acute renal failure, which was successfully treated with peritoneal dialysis. Peritoneal dialysis was started on the 5th day because the patient had been anuric for 48 h. At... Abstract

Cited 49 times since 2003 (2.3 per year) source: EuropePMC

Molecular biology of the cell, Volume 15, Issue 2, 14 2 2003, Pages 611-624 Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes. Fouraux MA, Deneka M, Ivan V, van der Heijden A, Raymackers J, van Suylekom D, van Venrooij WJ, van der Sluijs P, Pruijn GJ

We describe the characterization of an 80-kDa protein cross-reacting with a monoclonal antibody against the human La autoantigen. The 80-kDa protein is a variant of rabip4 with an N-terminal extension of 108 amino acids and is expressed in the same cells. For this reason, we named it rabip4'. rabip4' is a peripheral membrane protein, which colocalized with internalized transferrin and EEA1 on early endosomes. Membrane association required the presence of the FYVE domain and was perturb... Abstract

Cited 9 times since 2003 (0.4 per year) source: EuropePMC

The American journal of cardiology, Volume 92, Issue 10, 1 1 2003, Pages 1165-1170 Prognostic significance of fixed perfusion abnormalities on stress technetium-99m sestamibi single-photon emission computed tomography in patients without known coronary artery disease. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Poldermans D

Fixed perfusion abnormalities in patients with known coronary artery disease (CAD) are associated with myocardial damage and adverse outcomes. However, the significance of these abnormalities in patients without known CAD is unclear. The aim of this study was to assess the prognostic significance of fixed versus reversible perfusion abnormalities in patients without known CAD. We studied 327 patients (58 +/- 11 years of age; 215 men) with no history of myocardial infarction or revascularization,... Abstract

Cited 1 times since 2003 (0 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 76, Issue 5, 1 1 2003, Pages 1748 Evaluation of rerouting surgery of a coronary artery anomaly by magnetic resonance angiography. Salm LP, Bax JJ, Lamb HJ, Hazekamp MG, de Roos A, van der Wall EE, Vliegen HW

Abstract

Cited 57 times since 2003 (2.7 per year) source: EuropePMC

AJR. American journal of roentgenology, Volume 181, Issue 5, 1 1 2003, Pages 1355-1359 Comparison of CT and sonography in the diagnosis of acute appendicitis: a blinded prospective study. Poortman P, Lohle PN, Schoemaker CM, Oostvogel HJ, Teepen HJ, Zwinderman KA, Hamming JF

Objective: Our objective was to compare the accuracy of CT and sonography in a general community teaching hospital for the diagnosis of acute appendicitis in patients with suspected acute appendicitis. SUBJECTS AND METHODS. In this prospective study, 199 consecutive patients with clinical signs and symptoms of acute appendicitis were examined with sonography (graded compression technique) and CT (focused unenhanced single-detector helical CT [5-mm section thickness]. CT was performed from the L2... Abstract

Cited 1 times since 2003 (0 per year) source: EuropePMC

Perfusion, Volume 18, Issue 6, 1 1 2003, Pages 357-362 Increasing the antioxidative capacity of neonatal cardiopulmonary bypass prime solution: an in vitro study. Draaisma AM, Molicki JS, Verbeet N, Munneke R, Huysmans HA, Berger HM, Hazekamp MG

Inflammation and oxidative damage are believed to play an important role in the postoperative complications after cardiopulmonary bypass (CPB) in neonates. During the preparation of the prime, red blood cells (RBCs) release non-protein-bound iron (NPBI) and free haemoglobin/haem (Hb/haem). The presence of these prooxidants in the prime solution may increase oxidative stress in neonates undergoing CPB. The solution used as the basis of the prime solution may influence the degree of this oxidative... Abstract

Cited 57 times since 2003 (2.7 per year) source: EuropePMC

Archives of otolaryngology--head & neck surgery, Volume 129, Issue 11, 1 1 2003, Pages 1225-1229 Detection of Helicobacter pylori and its CagA gene in tonsil and adenoid tissues by PCR. Cirak MY, Ozdek A, Yilmaz D, Bayiz U, Samim E, Turet S

Objective: To determine the presence of Helicobacter pylori and, if detected, the prevalence of the CagA gene in adenotonsillectomy specimens by polymerase chain reaction (PCR). Design: A prospective clinical trial. Setting: Tertiary referral center. Patients and methods: The study population comprised 23 patients who had undergone adenoidectomy, tonsillectomy, or adenotonsillectomy under local or general anesthesia. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples obtaine... Abstract

Cited 288 times since 2003 (13.5 per year) source: EuropePMC

The American journal of cardiology, Volume 92, Issue 10, 1 1 2003, Pages 1238-1240 Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation. Bax JJ, Marwick TH, Molhoek SG, Bleeker GB, van Erven L, Boersma E, Steendijk P, van der Wall EE, Schalij MJ

We evaluated patients with end-stage heart failure who have a high likelihood of response to cardiac resynchronization therapy (biventricular pacing). It appears that 20% of patients do not respond to this expensive therapy despite the use of selection criteria (dilated cardiomyopathy, heart failure, New York Heart Association class II or IV, left ventricular ejection fraction 120 ms). The presence of left ventricular dyssynchrony is needed to result in improvement after cardiac resynchronizatio... Abstract

Cited 13 times since 2003 (0.6 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 10, Issue 6, 1 1 2003, Pages 615-622 Risk stratification of patients after myocardial revascularization by stress Tc-99m tetrofosmin myocardial perfusion tomography. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Poldermans D

Background: The aim of this study was to assess the incremental prognostic value of stress technetium 99m tetrofosmin imaging after myocardial revascularization. Methods and results: We studied 381 patients (aged 60 +/- 10 years, 270 men), 4.5 +/- 3.2 years after myocardial revascularization (coronary artery bypass grafting in 201 patients and percutaneous coronary intervention in 180 patients), who underwent exercise or dobutamine stress tetrofosmin single photon emission computed tomography. E... Abstract

Cited 134 times since 2003 (6.3 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 42, Issue 10, 1 1 2003, Pages 1818-1825 Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT. Abidov A, Bax JJ, Hayes SW, Hachamovitch R, Cohen I, Gerlach J, Kang X, Friedman JD, Germano G, Berman DS

Objectives: This study evaluated the prognostic value of transient ischemic dilation (TID) of the left ventricle (LV) in patients with normal stress myocardial perfusion single photon emission computed tomography (MPS). Background: The prognostic value of TID in patients with an otherwise normal MPS has not been defined. Methods: We identified 1,560 patients who had normal stress MPS (436 vasodilator and 1,124 exercise stress), and no rest LV enlargement (Population 1) and followed up for 2.30 +... Abstract

Cited 45 times since 2003 (2.1 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 286, Issue 2, 9 2 2003, Pages H723-30 Quantification of left ventricular mechanical dyssynchrony by conductance catheter in heart failure patients. Steendijk P, Tulner SA, Schreuder JJ, Bax JJ, van Erven L, van der Wall EE, Dion RA, Schalij MJ, Baan J

Mechanical dyssynchrony is an important codeterminant of cardiac dysfunction in heart failure. Treatment, either medical, surgical, or by pacing, may improve cardiac function partly by improving mechanical synchrony. Consequently, the quantification of ventricular mechanical (dys)synchrony may have important diagnostic and prognostic value and may help to determine optimal therapy. Therefore, we introduced new indexes to quantify temporal and spatial aspects of mechanical dyssynchrony derived fr... Abstract

Cited 63 times since 2003 (2.9 per year) source: EuropePMC

Circulation, Volume 108, Issue 16, 6 1 2003, Pages 1954-1959 Impact of viability, ischemia, scar tissue, and revascularization on outcome after aborted sudden death. van der Burg AE, Bax JJ, Boersma E, Pauwels EK, van der Wall EE, Schalij MJ

Background: Survivors of aborted sudden death attributable to ventricular arrhythmias in the presence of coronary artery disease are at risk for recurrences. The substrate underlying these arrhythmias is not clear, and therefore the relation between ischemia, viability, scar tissue (and revascularization), and the incidence of ventricular arrhythmias (and survival) was studied over up to 3 years. Methods and results: One hundred fifty-three survivors of sudden death underwent stress-rest perfusi... Abstract

Cited 25 times since 2003 (1.2 per year) source: EuropePMC

Radiology, Volume 229, Issue 2, 2 1 2003, Pages 513-519 Real-time MR imaging of aortic flow: influence of breathing on left ventricular stroke volume in chronic obstructive pulmonary disease. van den Hout RJ, Lamb HJ, van den Aardweg JG, Schot R, Steendijk P, van der Wall EE, Bax JJ, de Roos A

Purpose: To assess real-time changes of left ventricular stroke volume (SV) in relation to the breathing pattern in healthy subjects and in patients with chronic obstructive pulmonary disease (COPD). Materials and methods: Real-time magnetic resonance (MR) imaging flow measurements were performed in the ascending aorta of 10 healthy volunteers and nine patients with severe COPD. Breathing maneuvers were registered with an abdominal pressure belt, which was synchronized to the electrocardiographi... Abstract

Cited 29 times since 2003 (1.4 per year) source: EuropePMC

Archives of internal medicine, Volume 163, Issue 18, 1 1 2003, Pages 2230-2235 Optimizing long-term cardiac management after major vascular surgery: Role of beta-blocker therapy, clinical characteristics, and dobutamine stress echocardiography to optimize long-term cardiac management after major vascular surgery. Kertai MD, Boersma E, Bax JJ, Thomson IR, Cramer MJ, van de Ven LL, Scheffer MG, Trocino G, Vigna C, Baars HF, van Urk H, Roelandt JR, Poldermans D, Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography (DECREASE) Study Group

Background: Survivors of major vascular surgery are at increased risk of late cardiac complications. Objective: To examine the cardioprotective effect of beta-blockers. Methods: A follow-up study was conducted in 1286 patients who survived surgery for at least 30 days. Patients were screened for cardiac risk factors and dobutamine stress echocardiography (DSE) results; 1034 patients (80%) underwent preoperative DSE, and 370 (29%) received beta-blockers. The main outcome measure was late cardiac... Abstract