Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7429 results
Cited 21 times since 2011 (1.5 per year) source: EuropePMC
Cardiovascular diabetology, Volume 10, 19 3 2011, Pages 67 Association of plasma osteoprotegerin and adiponectin with arterial function, cardiac function and metabolism in asymptomatic type 2 diabetic men. Chen WJ, Rijzewijk LJ, van der Meer RW, Heymans MW, van Duinkerken E, Lubberink M, Lammertsma AA, Lamb HJ, de Roos A, Romijn JA, Smit JW, Bax JJ, Bjerre M, Frystyk J, Flyvbjerg A, Diamant M
Background: Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor receptor superfamily, is linked to cardiovascular disease. Negative associations exist between circulating OPG and cardiac function. The adipocytokine adiponectin (ADPN) is downregulated in type 2 diabetes mellitus (T2DM) and coronary artery disease and shows an inverse correlation with insulin sensitivity and cardiovascular disease risk. We assessed the relationship of plasma OPG and ADPN and arterial function, car... Abstract
Cited 51 times since 2011 (3.7 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 31, Issue 10, 14 2 2011, Pages 2338-2344 Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Welsh P, Murray HM, Ford I, Trompet S, de Craen AJ, Jukema JW, Stott DJ, McInnes IB, Packard CJ, Westendorp RG, Sattar N, PROSPER Study Group
Objective: The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD). Methods and results: In the PROSPER (PROspective Study of Pravastatin in the Elderly at Risk) cohort, we related baseline concentrations of circulating IL-10 to risk of CVD events in a nested case (n=819)-control (n=1618) study of 3.2 years of follow-up. Circulating IL-10 showed few strong associations with classical risk factors but was posit... Abstract
Cited 33 times since 2011 (2.4 per year) source: EuropePMC
Journal of magnetic resonance imaging : JMRI, Volume 34, Issue 3, 14 2 2011, Pages 526-531 Age-related and regional changes of aortic stiffness in the Marfan syndrome: assessment with velocity-encoded MRI. Westenberg JJ, Scholte AJ, Vaskova Z, van der Geest RJ, Groenink M, Labadie G, van den Boogaard PJ, Radonic T, Hilhorst-Hofstee Y, Mulder BJ, Kroft LJ, Reiber JH, de Roos A
Purpose: To study age-related change in aortic stiffness in patients with Marfan syndrome (MFS) versus healthy volunteers using velocity-encoded (VE) MRI. Materials and methods: Twenty-five MFS patients (age range, 18-63 years; mean age 36 ± 14 years, 13 men) and 25 age-/gender-matched healthy volunteers were examined with VE-MRI. Aortic stiffness was expressed by pulse wave velocity (PWV), assessed in the proximal and distal part of the aorta and in the total aorta. PWV was compared between pat... Abstract
Cited 22 times since 2011 (1.6 per year) source: EuropePMC
European radiology, Volume 21, Issue 11, 7 1 2011, Pages 2285-2296 Diagnostic performance of 320-slice multidetector computed tomography coronary angiography in patients after coronary artery bypass grafting. de Graaf FR, van Velzen JE, Witkowska AJ, Schuijf JD, van der Bijl N, Kroft LJ, de Roos A, Reiber JH, Bax JJ, de Grooth GJ, Jukema JW, van der Wall EE
Objectives: To evaluate the diagnostic performance of 320-slice computed tomography coronary angiography (CTA) in the evaluation of patients with prior coronary artery bypass grafting (CABG). Invasive coronary angiography (ICA) served as the standard of reference, using a quantitative approach. Methods: CTA studies were performed using CT equipment with 320 detector-rows, each 0.5 mm wide, and a gantry rotation time of 0.35 s. All grafts, recipient and nongrafted vessels were deemed interpretabl... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
Heart failure reviews, Volume 16, Issue 4, 1 1 2011, Pages 411-423 The role of nuclear imaging in the failing heart: myocardial blood flow, sympathetic innervation, and future applications. Boogers MJ, Fukushima K, Bengel FM, Bax JJ
Heart failure represents a common disease affecting approximately 5 million patients in the United States. Several conditions play an important role in the development and progression of heart failure, including abnormalities in myocardial blood flow and sympathetic innervation. Nuclear imaging represents the only imaging modality with sufficient sensitivity to assess myocardial blood flow and sympathetic innervation of the failing heart. Although nuclear imaging with single-photon emission comp... Abstract
Cited 11 times since 2011 (0.8 per year) source: EuropePMC
Journal of electrocardiology, Volume 44, Issue 4, 1 1 2011, Pages 453-459 Predictive power of T-wave alternans and of ventricular gradient hysteresis for the occurrence of ventricular arrhythmias in primary prevention cardioverter-defibrillator patients. Man S, De Winter PV, Maan AC, Thijssen J, Borleffs CJ, van Meerwijk WP, Bootsma M, van Erven L, van der Wall EE, Schalij MJ, Burattini L, Burattini R, Swenne CA
Background and purpose: Left ventricular ejection fraction lacks specificity to predict sudden cardiac death in heart failure. T-wave alternans (TWA; beat-to-beat T-wave instability, often measured during exercise) is deemed a promising noninvasive predictor of major cardiac arrhythmic event. Recently, it was demonstrated that TWA during recovery from exercise has additional predictive value. Another mechanism that potentially contributes to arrhythmogeneity is exercise-recovery hysteresis in ac... Abstract
Cited 3 times since 2011 (0.2 per year) source: EuropePMC
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, Volume 19, Issue 7, 1 1 2011, Pages 678-679 Successful electroconvulsive therapy in a 95-year-old man with a cardiac pacemaker--a case report. Gosselink MJ, Schenkeveld KW, Trines SA, van Vliet IM
Cited 2 times since 2011 (0.1 per year) source: EuropePMC
Pediatric research, Volume 70, Issue 1, 1 1 2011, Pages 37-43 Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias. Hahurij ND, Kolditz DP, Bökenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-De Groot AC, Blom NA
Atrioventricular reentry tachycardia (AVRT) requiring an accessory atrioventricular pathway (AP) is the most common type of arrhythmia in the perinatal period. The etiology of these arrhythmias is not fully understood as well as their capability to dissipate spontaneously in the first year of life. Temporary presence of APs during annulus fibrosus development might cause this specific type of arrhythmias. To study the presence of APs, electrophysiological recordings of ventricular activation pat... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
Journal of electrocardiology, Volume 44, Issue 4, 1 1 2011, Pages 410-415 Influence of the vectorcardiogram synthesis matrix on the power of the electrocardiogram-derived spatial QRS-T angle to predict arrhythmias in patients with ischemic heart disease and systolic left ventricular dysfunction. Man S, Algra AM, Schreurs CA, Borleffs CJ, Scherptong RW, van Erven L, van der Wall EE, Cannegieter SC, Schalij MJ, Swenne CA
Background and purpose: Several studies have demonstrated that the spatial mean QRS-T angle (SA) predicts cardiac events and mortality. Spatial mean QRS-T angle is a vectorcardiographic variable. Because in clinical practice, 12-lead standard electrocardiograms (ECGs) are recorded rather than vectorcardiograms (VCGs) according to Frank, VCGs are commonly obtained by synthesizing them from 12-lead ECGs, by using a VCG synthesis matrix. Hence, the thus computed SA is an estimate of the real SA mea... Abstract
The Annals of thoracic surgery, Volume 92, Issue 1, 1 1 2011, Pages 166 Invited commentary. Hazekamp MG
Cited 39 times since 2011 (2.9 per year) source: EuropePMC
Journal of dairy science, Volume 94, Issue 7, 1 1 2011, Pages 3213-3228 Invited review: associations between variables of routine herd data and dairy cattle welfare indicators. de Vries M, Bokkers EA, Dijkstra T, van Schaik G, de Boer IJ
As farm animal welfare is high on the political and societal agendas of many countries, considerable pressure exists to establish audit programs in which farm animal welfare is routinely monitored. On-farm assessment of animal welfare, however, is time-consuming and costly. A promising strategy to monitor animal welfare more efficiently is to first estimate the level of animal welfare on a farm based on routine herd data that are available in national databases. It is not currently known which v... Abstract
Cited 52 times since 2011 (3.8 per year) source: EuropePMC
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, Volume 47, Issue 2, 30 5 2011, Pages 90-97 Near-infrared fluorescence imaging in patients undergoing pancreaticoduodenectomy. Hutteman M, van der Vorst JR, Mieog JS, Bonsing BA, Hartgrink HH, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL
Background: Intraoperative visualization of pancreatic tumors has the potential to improve radical resection rates. Intraoperative visualization of the common bile duct and bile duct anastomoses could be of added value. In this study, we explored the use of indocyanine green (ICG) for these applications and attempted to optimize injection timing and dose. Methods: Eight patients undergoing a pancreaticoduodenectomy were injected intravenously with 5 or 10 mg ICG. During and after injection, the... Abstract
Cited 27 times since 2011 (2 per year) source: EuropePMC
Stroke research and treatment, Volume 2011, 30 5 2011, Pages 424759 Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality. Trompet S, Pons D, Kanse SM, de Craen AJ, Ikram MA, Verschuren JJ, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, Slagboom PE, Westendorp RG, Jukema JW
Introduction. The FSAP-Marburg I polymorphism (1704G > A), which reduces FSAP activity, is associated with late complications of carotid stenosis in humans. Therefore, this study examines the influence of the Marburg I polymorphism and the closely linked Marburg II polymorphism (1280G > C) on various cardiovascular outcomes in two large independent study populations. Methods. The two Marburg polymorphisms in the HABP2 gene encoding FSAP were genotyped in a large population of elderly patie... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 5, 28 4 2011, Pages 711-717 Prediction of response to cardiac resynchronization therapy combining two different three-dimensional analyses of left ventricular dyssynchrony. Auger D, Bertini M, Marsan NA, Hoke U, Ewe SH, Thijssen J, Witkowski TG, Yiu KH, Ng AC, van der Wall EE, Schalij MJ, Bax JJ, Delgado V
Triplane tissue synchronization imaging (TSI) and real-time 3-dimensional echocardiography (RT3DE) provide different characterizations of left ventricular (LV) mechanics and dyssynchrony. Triplane TSI assesses differences in time to peak systolic segmental myocardial tissue velocities, whereas RT3DE evaluates differences in time to minimum end-systolic regional volumes. Whether an approach using the 2 3D techniques predicts better significant reverse remodeling after cardiac resynchronization th... Abstract
Cited 51 times since 2011 (3.7 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 13, Issue 11, 28 4 2011, Pages 1533-1540 Prognostic value of total atrial conduction time estimated with tissue Doppler imaging to predict the recurrence of atrial fibrillation after radiofrequency catheter ablation. den Uijl DW, Gawrysiak M, Tops LF, Trines SA, Zeppenfeld K, Schalij MJ, Bax JJ, Delgado V
Aims: Total atrial activation time has been identified as an independent predictor of new-onset atrial fibrillation (AF). Echocardiographic assessment of PA-TDI duration provides an estimation of total atrial conduction time. The aim of this study was to investigate the prognostic value of total atrial conduction time to predict AF recurrence after radiofrequency catheter ablation (RFCA). Methods and results: In 213 patients undergoing RFCA for symptomatic drug-refractory paroxysmal AF, the tota... Abstract
Cited 23 times since 2011 (1.7 per year) source: EuropePMC
Acta physiologica (Oxford, England), Volume 203, Issue 4, 27 4 2011, Pages 409-418 The induction of mild hypothermia improves systolic function of the resuscitated porcine heart at no further sympathetic activation. Schwarzl M, Steendijk P, Huber S, Truschnig-Wilders M, Obermayer-Pietsch B, Maechler H, Pieske B, Post H
Aim: Mild hypothermia (MH) after cardiac arrest attenuates hypoxic brain injury and improves survival. As MH increases contractility in normal hearts, we hypothesized that MH improves cardiovascular function after cardiac arrest. Methods: In 16 anaesthetized pigs (64 ± 2 kg), ventricular fibrillation was induced electrically for 5 min. At 10 min after resuscitation and return of spontaneous circulation (ROSC), pigs were assigned to normothermia (NT, 38°C, n = 8) or MH (33°C, n = 8, intravascular... Abstract
Cited 25 times since 2011 (1.8 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 5, 22 4 2011, Pages 658-664 Comparison of the relation between the calcium score and plaque characteristics in patients with acute coronary syndrome versus patients with stable coronary artery disease, assessed by computed tomography angiography and virtual histology intravascular ultrasound. van Velzen JE, de Graaf FR, Jukema JW, de Grooth GJ, Pundziute G, Kroft LJ, de Roos A, Reiber JH, Bax JJ, Schalij MJ, Schuijf JD, van der Wall EE
A considerable number of patients with an acute coronary syndrome (ACS) who present with a 0 or low calcium score (CS) still demonstrate coronary artery disease (CAD) and significant stenosis. The aim of the present study was to evaluate the relation between the CS and the degree and character of atherosclerosis in patients with suspected ACS versus patients with stable CAD obtained by computed tomography angiography and virtual histology intravascular ultrasound (VH IVUS). Overall 112 patients... Abstract
Cited 9 times since 2011 (0.7 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 38, Issue 10, 21 3 2011, Pages 1899-1907 Impaired cardiac sympathetic innervation in symptomatic patients with long QT syndrome. Kies P, Paul M, Gerss J, Stegger L, Mönnig G, Schober O, Wichter T, Schäfers M, Schulze-Bahr E
Purpose: Increased sympathetic activation is a key modifier for arrhythmogenesis in patients with long QT syndrome (LQTS), a congenital channelopathy. Therefore, we investigated cardiac sympathetic function using 123I-metaiodobenzylguanidine (MIBG) single photon emission computed tomography (SPECT) in a cohort of symptomatic LQTS patients and correlated these findings with the underlying genotype. Methods: [123I]MIBG SPECT was performed in 28 LQTS patients. Among these, 18 patients (64%) had a p... Abstract
Cited 1 times since 2011 (0.1 per year) source: EuropePMC
Nurse education today, Volume 32, Issue 4, 17 3 2011, Pages 373-377 Student nurses' perceptions of mental health care: validation of a questionnaire. van der Heijden A, van der Bijl J, Latour CH, Hoekstra H, van Meijel B
Aim: This article describes the results of a study into the psychometric properties of a questionnaire about student nurses' perceptions of mental health care. The questionnaire was constructed in 2008, but has not yet been tested in terms of construct validity and reliability. A validated questionnaire is essential as a standardized method of analyzing student nurses' perceptions of mental health care. Method: To investigate the construct validity, an exploratory factor analysis was p... Abstract
Cited 33 times since 2011 (2.4 per year) source: EuropePMC
Metabolic engineering, Volume 13, Issue 5, 17 3 2011, Pages 518-526 Increasing free-energy (ATP) conservation in maltose-grown Saccharomyces cerevisiae by expression of a heterologous maltose phosphorylase. de Kok S, Yilmaz D, Suir E, Pronk JT, Daran JM, van Maris AJ
Increasing free-energy conservation from the conversion of substrate into product is crucial for further development of many biotechnological processes. In theory, replacing the hydrolysis of disaccharides by a phosphorolytic cleavage reaction provides an opportunity to increase the ATP yield on the disaccharide. To test this concept, we first deleted the native maltose metabolism genes in Saccharomyces cerevisiae. The knockout strain showed no maltose-transport activity and a very low residual... Abstract