Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6173 results
Cited 17 times since 2022 (6.4 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 15, Issue 17, 1 1 2022, Pages 1711-1722 Outcomes After Transcatheter Edge-to-Edge Mitral Valve Repair According to Mitral Regurgitation Etiology and Cardiac Remodeling. Yoon SH, Makar M, Kar S, Chakravarty T, Oakley L, Sekhon N, Koseki K, Nakamura M, Hamilton M, Patel JK, Singh S, Skaf S, Siegel RJ, Bax JJ, Makkar RR
Background: Transcatheter edge-to-edge repair (TEER) has been increasingly used for selected patients with mitral regurgitation (MR), but limited data are available regarding clinical outcomes in patients with varied etiology and mechanism of MR. Objectives: The aim of this study was to evaluate the outcomes of TEER according to etiology and left ventricular (LV) and left atrial remodeling. Methods: Consecutive patients who underwent TEER between 2007 and 2020 were included in the analysis. Amon... Abstract
Cited 1 times since 2022 (0.4 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 10, 1 1 2022, Pages 1302-1303 Echocardiography to identify cardiac amyloidosis in patients with calcific aortic stenosis. van der Bijl P, Stassen J, Bax JJ
Cited 5 times since 2022 (1.9 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 35, Issue 4, 1 1 2022, Pages ivac108 Robotic coronary revascularization in Europe, state of art and future of EACTS-endorsed Robotic Cardiothoracic Surgery Taskforce. Pettinari M, Gianoli M, Palmen M, Cerny S, Onan B, Singh S, Segers P, Bolcal C, Alhan C, Navarra E, De Praetere H, Vojacek J, Cebotaru T, Modi P, Doguet F, Franke U, Ouda A, Melly L, Malapert G, Labrousse L, Agnino A, Philipsen T, Jansens JL, Folliguet T, Pereda D, Musumeci F, Suwalski P, Cathenis K, Van Praet F, Bonatti J, Oosterlinck W, European Robotic CardioThoracic Surgeons (ERCTS)
Cited 9 times since 2022 (3.4 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 24, Issue 8, 1 1 2022, Pages 1291-1299 Tricuspid regurgitation after cardiac resynchronization therapy: evolution and prognostic significance. Stassen J, Galloo X, Hirasawa K, Marsan NA, van der Bijl P, Delgado V, Bax JJ
Aims: Tricuspid regurgitation (TR) is common in patients with heart failure (HF) and is associated with worse outcome. This study investigated the effect of cardiac resynchronization therapy (CRT) on TR severity and long-term outcome. Methods and results: Tricuspid regurgitation severity was assessed at baseline and 6 months after CRT implantation, using a multiparametric approach. Patients were divided into four groups: (i) no or mild TR without progression; (ii) no or mild TR with progression... Abstract
Cited 12 times since 2022 (4.5 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 10, 1 1 2022, Pages 1326-1335 Left ventricular remodelling patterns in patients with moderate aortic stenosis. Stassen J, Ewe SH, Hirasawa K, Butcher SC, Singh GK, Amanullah MR, Sin KYK, Ding ZP, Pio SM, Chew NWS, Sia CH, Kong WKF, Poh KK, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Aims: Moderate aortic stenosis (AS) is associated with an increased risk of adverse events. Because outcomes in patients with AS are ultimately driven by the condition of the left ventricle (LV) and not by the valve, assessment of LV remodelling seems important for risk stratification. This study evaluated the association between different LV remodelling patterns and outcomes in patients with moderate AS. Methods and results: Patients with moderate AS (aortic valve area 1.0-1.5 cm2) were identif... Abstract
Cited 11 times since 2022 (4.2 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 24, Issue 8, 1 1 2022, Pages 1223-1228 Association between left atrial epicardial fat, left atrial volume, and the severity of atrial fibrillation. van Rosendael AR, Smit JM, El'Mahdiui M, van Rosendael PJ, Leung M, Delgado V, Bax JJ
Aims: Left atrial (LA) volume and LA epicardial fat are both substrates for atrial fibrillation (AF), but may relate with AF at different (early vs. late) stages in the AF disease process. We evaluated associations between LA epicardial fat and LA volume in patients with sinus rhythm (SR), paroxysmal AF (PAF), and persistent/permanent AF. Methods and results: In total, 300 patients (100 with SR, 100 with PAF, and 100 with persistent/permanent AF) who underwent cardiac computed tomography angiogr... Abstract
Cited 24 times since 2022 (9.1 per year) source: EuropePMC
Nature communications, Volume 13, Issue 1, 1 1 2022, Pages 5144 Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Young WJ, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody JA, Salman R, Noordam R, Benjamins JW, Haessler J, Lyytikäinen LP, Repetto L, Concas MP, van den Berg ME, Weiss S, Baldassari AR, Bartz TM, Cook JP, Evans DS, Freudling R, Hines O, Isaksen JL, Lin H, Mei H, Moscati A, Müller-Nurasyid M, Nursyifa C, Qian Y, Richmond A, Roselli C, Ryan KA, Tarazona-Santos E, Thériault S, van Duijvenboden S, Warren HR, Yao J, Raza D, Aeschbacher S, Ahlberg G, Alonso A, Andreasen L, Bis JC, Boerwinkle E, Campbell A, Catamo E, Cocca M, Cutler MJ, Darbar D, De Grandi A, De Luca A, Ding J, Ellervik C, Ellinor PT, Felix SB, Froguel P, Fuchsberger C, Gögele M, Graff C, Graff M, Guo X, Hansen T, Heckbert SR, Huang PL, Huikuri HV, Hutri-Kähönen N, Ikram MA, Jackson RD, Junttila J, Kavousi M, Kors JA, Leal TP, Lemaitre RN, Lin HJ, Lind L, Linneberg A, Liu S, MacFarlane PW, Mangino M, Meitinger T, Mezzavilla M, Mishra PP, Mitchell RN, Mononen N, Montasser ME, Morrison AC, Nauck M, Nauffal V, Navarro P, Nikus K, Pare G, Patto
The QT interval is an electrocardiographic measure representing the sum of ventricular depolarization and repolarization, estimated by QRS duration and JT interval, respectively. QT interval abnormalities are associated with potentially fatal ventricular arrhythmia. Using genome-wide multi-ancestry analyses (>250,000 individuals) we identify 177, 156 and 121 independent loci for QT, JT and QRS, respectively, including a male-specific X-chromosome locus. Using gene-based rare-variant methods,... Abstract
Cited 21 times since 2022 (8 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 80, Issue 11, 1 1 2022, Pages 1045-1056 Clinical Outcomes in Patients With Dilated Cardiomyopathy and Ventricular Tachycardia. Zeppenfeld K, Wijnmaalen AP, Ebert M, Baldinger SH, Berruezo A, Catto V, Vaseghi M, Arya A, Kumar S, de Riva M, Deneke T, Gaspar T, Soejima K, van Rein N, Tedrow UB, Piorkowski C, Shivkumar K, Carbucicchio C, Hindricks G, Stevenson WG
Background: Recurrent ventricular tachycardia (VT) due to dilated cardiomyopathy (DCM) is difficult to treat, and long-term outcome data are limited. Objectives: The aim of this study was to identify predictors of mortality or heart transplantation (HTx) and VT recurrence. Methods: Consecutive patients with DCM accepted for radiofrequency catheter ablation (RFCA) of VT at 9 centers were prospectively enrolled and followed. Results: Of 281 consecutive patients (mean age 60 ± 13 years, 85% men, me... Abstract
Cited 12 times since 2022 (4.5 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 80, Issue 11, 1 1 2022, Pages 1071-1084 Impact of Left Ventricular Ejection Fraction on Clinical Outcomes in Bicuspid Aortic Valve Disease. Hecht S, Butcher SC, Pio SM, Kong WKF, Singh GK, Ng ACT, Perry R, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Gay LG, Fijałkowski M, Liang M, Tay E, Marsan NA, Selvanayagam J, Pinto F, Zamorano JL, Evangelista A, Delgado V, Bax JJ, Pibarot P
Background: The prognostic impact of left ventricular ejection fraction (LVEF) in patients with bicuspid aortic valve (BAV) disease has not been previously studied. Objectives: The purpose of this study was to determine the prognostic impact of LVEF in BAV patients according to the type of aortic valve dysfunction. Methods: We retrospectively analyzed the data collected in 2,672 patients included in an international registry of patients with BAV. Patients were classified according to the type of... Abstract
Cited 6 times since 2022 (2.3 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 10, 1 1 2022, Pages 1273-1276 How to assess severe tricuspid regurgitation by echocardiography? Sade LE, Muraru D, Marsan NA, Agricola E, Stankovic I, Stankovic I, Donal E
Cited 2 times since 2022 (0.8 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 10, 1 1 2022, Pages 1314-1323 Early versus late acute coronary syndrome risk patterns of coronary atherosclerotic plaque. van den Hoogen IJ, Stuijfzand WJ, Gianni U, van Rosendael AR, Bax AM, Lu Y, Tantawy SW, Hollenberg EJ, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Gonçalves PA, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Danad I, Gransar H, Budoff MJ, Samady H, Virmani R, Berman DS, Chang HJ, Narula J, Min JK, Bax JJ, Lin FY, Shaw LJ, ICONIC Investigators
Aims: The temporal instability of coronary atherosclerotic plaque preceding an incident acute coronary syndrome (ACS) is not well defined. We sought to examine differences in the volume and composition of coronary atherosclerosis between patients experiencing an early (≤90 days) versus late ACS (>90 days) after baseline coronary computed tomography angiography (CCTA). Methods and results: From a multicenter study, we enrolled patients who underwent a clinically indicated baseline CCTA and exp... Abstract
Cited 16 times since 2022 (6.1 per year) source: EuropePMC
JAMA dermatology, Volume 158, Issue 9, 1 1 2022, Pages 1048-1056 Dupilumab Drug Survival and Associated Predictors in Patients With Moderate to Severe Atopic Dermatitis: Long-term Results From the Daily Practice BioDay Registry. Spekhorst LS, de Graaf M, Zuithoff NPA, van den Reek JMPA, Kamsteeg M, Boesjes CM, Romeijn GLE, Loman L, Haeck I, Oosting AJ, de Boer-Brand A, Touwslager WRH, Flinterman A, van Lynden-van Nes AMT, Gostynski AH, de Bruin-Weller MS, Schuttelaar ML
Importance: Long-term data on dupilumab drug survival in patients with atopic dermatitis (AD) are scarce. Furthermore, little is known about the factors associated with drug survival of dupilumab in AD. Objective: To describe the drug survival of dupilumab in patients with AD and to identify associated predictors. Design, setting, and participants: This cohort study was based on data from the multicenter prospective daily practice BioDay registry, in which 4 university and 10 nonuniversity hospi... Abstract
Cited 1 times since 2022 (0.4 per year) source: EuropePMC
The American journal of cardiology, Volume 182, 30 5 2022, Pages 83-88 Comparison of the Quantity of Calcium in the Aortic Valve and the Coronary Arteries in Men Versus Women Who Underwent Transcatheter Aortic Valve Implantation. Singh GK, Vollema EM, Stassen J, van Rosendael A, Gegenava T, van der Kley F, Knuuti J, Marsan NA, Delgado V, Bax JJ
Several studies have shown an association between aortic stenosis (AS) and coronary atherosclerosis. This study aimed to evaluate the gender differences in aortic valve calcium (AVC) and coronary artery calcium (CAC) and the association between CAC and all-cause mortality in patients with severe AS. A total of 260 patients (80 ± 7 years, 39% men) with severe AS who were scheduled for transcatheter aortic valve implantation (TAVI) were included. AVC and CAC before TAVI were assessed by noncontras... Abstract
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Volume 168, 29 5 2022, Pages 113393 The role of diet in genotoxicity of fecal water derived from IBD patients and healthy controls. Wang S, Godschalk R, Spooren C, de Graaf M, Jonkers D, van Schooten FJ
Certain dietary factors with anti-inflammatory and/or anti-cancer properties would be a promising preventive strategy for inflammatory bowel disease (IBD) patients against developing colitis-associated colorectal cancer (CAC). In this study, fecal water (FW) was obtained from 80 IBD patients and 20 healthy controls (HCs). The comet assay was applied to determine the DNA damage induced by FW, and the protective potential of FW against hydrogen peroxide (H2O2) induced DNA damage in Caco-2 cells. I... Abstract
Cited 2 times since 2022 (0.8 per year) source: EuropePMC
Journal of electrocardiology, Volume 74, 27 4 2022, Pages 94-100 Diagnostic efficacy of ECG-derived ventricular gradient for the detection of chronic thromboembolic pulmonary hypertension in patients with acute pulmonary embolism. Luijten D, Meijer FMM, Boon GJAM, Ende-Verhaar YM, Bavalia R, El Bouazzaoui LH, Delcroix M, Huisman MV, Mairuhu ATA, Middeldorp S, Pruszcyk P, Ruigrok D, Verhamme P, Vonk Noordegraaf A, Vriend JWJ, Vliegen HW, Klok FA
Introduction: Application of the chronic thromboembolic pulmonary hypertension (CTEPH) rule out criteria (manual electrocardiogram [ECG] reading and N-terminal pro-brain natriuretic peptide [NTproBNP] test) can rule out CTEPH in pulmonary embolism (PE) patients with persistent dyspnea (InShape II algorithm). Increased pulmonary pressure may also be identified using automated ECG-derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO). Method: A predefined analysi... Abstract
Cited 13 times since 2022 (4.9 per year) source: EuropePMC
Hepatology communications, Volume 6, Issue 11, 27 4 2022, Pages 3163-3174 Left atrial dysfunction is an independent predictor of mortality in patients with cirrhosis treated by transjugular intrahepatic portosystemic shunt. Meucci MC, Hoogerduijn Strating MM, Butcher SC, van Rijswijk CSP, Van Hoek B, Van Hoek B, Delgado V, Bax JJ, Tushuizen ME, Marsan NA
The present study aimed to investigate (1) the association between left ventricular diastolic dysfunction (LVDD), graded according to the algorithm proposed by the Cirrhotic Cardiomyopathy Consortium, and long-term survival in patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt (TIPS) and (2) the additive prognostic value of left atrial (LA) function, as assessed by LA reservoir strain, using two-dimensional speckle-tracking echocardiography (2D-STE). A total of 129... Abstract
Cited 27 times since 2022 (10.1 per year) source: EuropePMC
Journal of medical Internet research, Volume 24, Issue 8, 24 4 2022, Pages e34229 The Barriers and Facilitators of eHealth-Based Lifestyle Intervention Programs for People With a Low Socioeconomic Status: Scoping Review. Al-Dhahir I, Reijnders T, Faber JS, van den Berg-Emons RJ, Janssen VR, Kraaijenhagen RA, Visch VT, Chavannes NH, Evers AWM
Background: Promoting health behaviors and preventing chronic diseases through a healthy lifestyle among those with a low socioeconomic status (SES) remain major challenges. eHealth interventions are a promising approach to change unhealthy behaviors in this target group. Objective: This review aims to identify key components, barriers, and facilitators in the development, reach, use, evaluation, and implementation of eHealth lifestyle interventions for people with a low SES. This review provide... Abstract
Cited 3 times since 2022 (1.1 per year) source: EuropePMC
American journal of medical genetics. Part A, Volume 188, Issue 12, 24 4 2022, Pages 3510-3515 Sacral abnormalities including caudal appendage, skeletal dysplasia, and prenatal cardiomyopathy associated with a pathogenic TAB2 variant in a 3-generation family. Koene S, Klerx-Melis F, Roest AAW, Kleijwegt MC, Bootsma M, Haak MC, van Haeringen MH, Ruivenkamp CAL, Nibbeling EAR, van Haeringen A
Haplo-insufficiency of the TGFβ-activated kinase 1 binding protein 2 (TAB2) gene is associated with short stature, facial dysmorphisms, connective tissue abnormalities, hearing loss, and cardiac disease. Skeletal dysplasia and sacral dimples are also found in a minority of patients. Here, we describe a 3-generation family with caudal appendage, other sacral anomalies, and skeletal abnormalities including hypoplasia of the iliac wings and scapulae, fusion of the carpal bones and stenosis of the s... Abstract
Cited 8 times since 2022 (3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 38, Issue 12, 24 4 2022, Pages 2781-2789 Vessel and sex differences in pericoronary adipose tissue attenuation obtained with coronary CT in individuals without coronary atherosclerosis. van Rosendael SE, Kuneman JH, van den Hoogen IJ, Kitslaar PH, van Rosendael AR, van der Bijl P, Reiber JHC, Ajmone Marsan N, Jukema JW, Knuuti J, Bax JJ
Pericoronary adipose tissue (PCAT) attenuation, derived from coronary computed tomography angiography (CCTA), is associated with coronary artery inflammation. Values for PCAT attenuation in men and women without atherosclerosis on CCTA are lacking. The aim of the current study was to assess the mean PCAT attenuation in individuals without coronary artery atherosclerosis on CCTA. Data on PCAT attenuation in men and women without coronary artery atherosclerosis on CCTA were included in this retros... Abstract
Journal of clinical lipidology, Volume 16, Issue 5, 23 4 2022, Pages 747-756 Relation of red blood cell distribution width to risk of major adverse cardiovascular events, death, and effect of alirocumab after acute coronary syndromes. Moriarty PM, Steg PG, McGinniss J, Zeiher AM, White HD, Manvelian G, Pordy R, Loy M, Jukema JW, Harrington RA, Gray JV, Gorby LK, Goodman SG, Diaz R, Bittner VA, Bhatt DL, Szarek M, Schwartz GG, ODYSSEY OUTCOMES Investigators
Elevated red blood cell distribution width (RDW) is associated with increased risk for major adverse cardiovascular events (MACE) and death in patients with cardiovascular disease. The ODYSSEY OUTCOMES trial compared alirocumab with placebo in 18,924 patients with recent acute coronary syndrome (ACS) and elevated atherogenic lipoproteins despite optimized statin treatment. This post hoc analysis determined whether RDW independently predicts risk of MACE and death in patients after recent ACS, wh... Abstract