6173 results
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
International journal of cardiology. Congenital heart disease,
Volume 9, 12 2 2022, Pages 100373
Strategies for low-molecular-weight heparin management in pregnant women with mechanical prosthetic heart valves: A nationwide survey of Dutch practice.
Voortman M, Roos JW, Slomp J, van Dijk APJ, Bouma BJ, Sieswerda GTJ, Kiès P, Boer A, Waskowsky WM, von Birgelen C, Wagenaar LJ
Background: In this study we investigated current Dutch practice of low molecular weight heparin (LMWH) treatment in pregnant women with mechanical prosthetic heart valves (MPHV) in order to evaluate how management can be optimized. Methods: Between December 2020 and February 2021, we conducted a survey among Dutch congenital cardiologists of tertiary centers in the Netherlands. We collected and analyzed written, unstructured, open questionnaires that were send to all 8 specialized pregnancy hea...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
JACC. Asia,
Volume 2, Issue 3, 12 2 2022, Pages 311-319
Longitudinal Quantitative Assessment of Coronary Atherosclerotic Plaque Burden Related to Serum Hemoglobin Levels.
Won KB, Lee BK, Heo R, Park HB, Lin FY, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, de Araújo Gonçalves P, Leipsic JA, Lee SE, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Berman DS, Narula J, Bax JJ, Min JK, Chang HJ
Background: Despite a potential role of hemoglobin in atherosclerosis, data on coronary plaque volume changes (PVC) related to serum hemoglobin levels are limited. Objectives: The authors sought to evaluate coronary atherosclerotic plaque burden changes related to serum hemoglobin levels using serial coronary computed tomographic angiography (CCTA). Methods: A total of 830 subjects (age 61 ± 10 years, 51.9% male) who underwent serial CCTA were analyzed. The median interscan period was 3.2 (IQR:...
Abstract
Cited 7 times since 2022 (2.3 per year)
source: EuropePMC
Journal of ultrasound,
Volume 25, Issue 4, 8 2 2022, Pages 957-963
The role of sonographic optic nerve sheath diameter measurements in pediatric head trauma.
Şık N, Ulusoy E, Çitlenbik H, Öztürk A, Er A, Yılmaz D, Duman M
Purpose: To determine the accuracy of bedside sonographic measurements of optic nerve sheath diameter (ONSD) and ONSD/eyeball transverse (ETD) diameter ratios to predict space-occupying lesions (SOLs) or elevated intracranial pressure (ICP) in pediatric head trauma. Methods: Children who presented to the emergency department with head trauma and underwent cranial computed tomography (CT) were enrolled and examined by ocular ultrasonography (US), and the ONSD was measured at 3 mm posterior to the...
Abstract
Cited 11 times since 2022 (3.6 per year)
source: EuropePMC
Bone research,
Volume 10, Issue 1, 6 1 2022, Pages 33
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing.
Ahmad M, Krüger BT, Kroll T, Vettorazzi S, Dorn AK, Mengele F, Lee S, Nandi S, Yilmaz D, Stolz M, Tangudu NK, Vázquez DC, Pachmayr J, Cirstea IC, Spasic MV, Ploubidou A, Ignatius A, Tuckermann J
Identification of regulators of osteoblastogenesis that can be pharmacologically targeted is a major goal in combating osteoporosis, a common disease of the elderly population. Here, unbiased kinome RNAi screening in primary murine osteoblasts identified cyclin-dependent kinase 5 (Cdk5) as a suppressor of osteoblast differentiation in both murine and human preosteoblastic cells. Cdk5 knockdown by siRNA, genetic deletion using the Cre-loxP system, or inhibition with the small molecule roscovitine...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
European stroke journal,
Volume 7, Issue 2, 6 1 2022, Pages 180-187
Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients - study rationale and protocol of the CORONIS study: A multicentre prospective cohort study.
van Lith TJ, Sluis WM, Wijers NT, Meijer FJ, Kamphuis-van Ulzen K, de Bresser J, Dankbaar JW, van den Heuvel FM, Antoni ML, Mulders-Manders CM, de Mast Q, van de Veerdonk FL, Klok FA, Tuladhar AM, Cannegieter SC, Wermer MJ, van der Worp HB, Huisman MV, de Leeuw FE
Background: COVID-19 is often complicated by thrombo-embolic events including ischemic stroke. The underlying mechanisms of COVID-19-associated ischemic stroke, the incidence and risk factors of silent cerebral ischemia, and the long-term functional outcome in these patients are currently unknown. Patients and methods: CORONavirus and Ischemic Stroke (CORONIS) is a multicentre prospective cohort study investigating the prevalence, risk factors and long-term incidence of (silent) cerebral ischemi...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 5, 1 1 2022, Pages 590-597
EACVI survey on hypertrophic cardiomyopathy.
Podlesnikar T, Cardim N, Ajmone Marsan N, D'Andrea A, Cameli M, Popescu BA, Schulz-Menger J, Stankovic I, Toplisek J, Maurer G, Haugaa KH, Dweck MR
Aims: The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey to evaluate current practice for the assessment and management of patients with hypertrophic cardiomyopathy (HCM). Methods and results: A total of 213 centres from 38 different countries (87% European) responded to the survey. One hundred twenty-one (57%) centres followed HCM patients in a general cardiology outpatient clinic and 85 (40%) centres in a specialized HCM/cardio...
Abstract
Cited 20 times since 2022 (6.5 per year)
source: EuropePMC
The lancet. Diabetes & endocrinology,
Volume 10, Issue 5, 1 1 2022, Pages 330-340
Metabolic risk factors and effect of alirocumab on cardiovascular events after acute coronary syndrome: a post-hoc analysis of the ODYSSEY OUTCOMES randomised controlled trial.
Ostadal P, Steg PG, Poulouin Y, Bhatt DL, Bittner VA, Chua T, Diaz R, Goodman SG, Huo Y, Jukema JW, Karpov Y, Pordy R, Scemama M, Szarek M, White HD, Schwartz GG, ODYSSEY OUTCOMES Investigators
Background: Many patients with acute coronary syndrome have concurrent metabolic risk factors that affect risk of major adverse cardiovascular events (MACE). We aimed to assess the effects of the PCSK9 inhibitor alirocumab compared with placebo on MACE according to baseline metabolic risk factors. Methods: We performed a post-hoc analysis of the ODYSSEY OUTCOMES trial, which was a multicentre, double-blind, randomised controlled trial done in 1315 hospitals and outpatient clinics in 57 countries...
Abstract
Cited 8 times since 2022 (2.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 5, 1 1 2022, Pages 699-707
Prognostic implications of left ventricular myocardial work index in patients with ST-segment elevation myocardial infarction and reduced left ventricular ejection fraction.
Butcher SC, Lustosa RP, Abou R, Marsan NA, Bax JJ, Delgado V
Aims: This study aimed to determine whether lower values of left ventricular (LV) global work index (GWI) at baseline were associated with a reduction in LV functional recovery and poorer long-term prognosis in patients with reduced LV ejection fraction (LVEF ≤40%) following ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 197 individuals (62 ± 12 years, 75% male) with STEMI treated with primary percutaneous coronary intervention and reduced LVEF were evaluated...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 173, 1 1 2022, Pages 48-55
Meta-Analysis of Bilateral Versus Single Internal Thoracic Artery Grafting in Patients ≥70 Years of Age.
Mulder BS, Candura D, Schoones JW, Etnel JRG, Schouten GN, de Weger A, Tomšič A, Klautz RJM
The optimal choice of graft material in patients ≥70 years of age undergoing coronary artery bypass grafting remains unknown. A systematic review of literature was conducted by searching PubMed, Embase, Web of Science, and Cochrane Library databases for original publications that compared bilateral internal thoracic artery (BITA) grafting with single internal thoracic artery grafting in patients ≥70 years of age. Data were extracted by 2 independent investigators and meta-analyzed with the use o...
Abstract
Cited 15 times since 2022 (4.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 173, 1 1 2022, Pages 120-127
Prognostic Implications of Right Ventricular Systolic Dysfunction in Cardiac Amyloidosis.
Tjahjadi C, Fortuni F, Stassen J, Debonnaire P, Lustosa RP, Marsan NA, Delgado V, Bax JJ
Left ventricular (LV) systolic dysfunction in cardiac amyloidosis (CA) is associated with poor prognosis. This study aimed to investigate the prognostic implications of right ventricular (RV) systolic dysfunction in CA. A total of 93 patients diagnosed with CA who underwent standard and speckle-tracking echocardiography were included. During a median follow-up of 17 (5 to 38) months, 42 patients (45%) died. Nonsurvivors were more likely to present with immunoglobulin light-chain amyloidosis and...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
Current health sciences journal,
Volume 48, Issue 2, 1 1 2022, Pages 169-175
Determining Covid-19 Vaccine Literacy Levels of Nursing Students.
Yilmaz D, Yilmaz DU, Yönt GH
This study aimed to determine nursing students' levels of COVID-19 vaccine literacy and the affecting variables. This descriptive research was carried out on 391 students receiving education at Bursa Uludağ University Nursing Department between January and March 2022. Research data were collected using a "Student Introduction Form" and the "COVID-19 Vaccine Literacy Scale". The mean total score of the nursing students included in the study on the COVID-19 Vaccine Literac...
Abstract
Cited 13 times since 2022 (4.2 per year)
source: EuropePMC
European heart journal,
Volume 43, Issue 16, 1 1 2022, Pages 1554-1565
Alirocumab after acute coronary syndrome in patients with a history of heart failure.
White HD, Schwartz GG, Szarek M, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Goodman SG, Jukema JW, Loy M, Pagidipati N, Pordy R, Ristić AD, Zeiher AM, Wojdyla DM, Steg PG, ODYSSEY OUTCOMES Investigators
Aims: Patients with heart failure (HF) have not been shown to benefit from statins. In a post hoc analysis, we evaluated outcomes in ODYSSEY OUTCOMES in patients with vs. without a history of HF randomized to the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor alirocumab or placebo. Methods and results: Among 18 924 patients with recent acute coronary syndrome (ACS) receiving intensive or maximum-tolerated statin treatment, the primary outcome of major adverse cardiovascular even...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
European journal of radiology open,
Volume 9, 31 5 2022, Pages 100417
Correlation between quantification of myocardial area at risk and ischemic burden at cardiac computed tomography.
van Driest FY, Bijns CM, van der Geest RJ, Broersen A, Dijkstra J, Jukema JW, Scholte AJHA
Purpose: This study aims to investigate the correlation between myocardial area at risk at coronary computed tomography angiography (CCTA) and the ischemic burden derived from myocardial computed tomography perfusion (CTP) by using the 17-segment model. Methods: Forty-two patients with chest pain complaints who underwent a combined CCTA and CTP protocol were identified. Patients with reversible ischemia at CTP and at least one stenosis of ≥ 50% at CCTA were selected. Myocardial area at risk was...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 30, Issue 1, 30 5 2022, Pages 321-323
Application of a deep learning algorithm to calcium scoring in myocardial perfusion imaging.
van der Bijl P, Stassen J, Bax JJ
Abstract
Cited 16 times since 2022 (5.2 per year)
source: EuropePMC
ESC heart failure,
Volume 9, Issue 3, 30 5 2022, Pages 2007-2012
The first experience with sodium-glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure.
Egorova AD, Nederend M, Tops LF, Vliegen HW, Jongbloed MRM, Kiès P
In congenitally corrected transposition of the great arteries, the morphological right ventricle supports the systemic circulation. This chronic exposure to pressure overload ultimately leads to systemic right ventricular (sRV) dysfunction and heart failure. Pharmacological options for the treatment of sRV failure are poorly defined and no solid recommendations are made in the most recent guidelines. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a new class of antihyperglycaemic drugs t...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
European heart journal open,
Volume 2, Issue 3, 29 5 2022, Pages oeac022
Determinants of label non-adherence to non-vitamin K oral anticoagulants in patients with newly diagnosed atrial fibrillation.
Seelig J, Trinks-Roerdink EM, Chu G, Pisters R, Theunissen LJHJ, Trines SA, Pos L, Kirchhof CJHJ, de Jong SFAMS, den Hartog FR, van Alem AP, Polak PE, Tieleman RG, van der Voort PH, Lenderink T, Otten AM, de Jong JSSG, Gu YL, Luermans JGLM, Kruip MJHA, Timmer SAJ, de Vries TAC, Cate HT, Geersing GJ, Rutten FH, Huisman MV, Hemels MEW
Aims: To evaluate the extent and determinants of off-label non-vitamin K oral anticoagulant (NOAC) dosing in newly diagnosed Dutch AF patients. Methods and results: In the DUTCH-AF registry, patients with newly diagnosed AF (
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 10, 29 5 2022, Pages 481-485
Percutaneous left atrial appendage closure reduces cost of care independent of the institutional cumulative caseload in patients with non-valvular atrial fibrillation.
D'Ancona G, Arslan F, Safak E, Weber D, Ince H
Background: Data on the impact of the cumulative percutaneous left atrial appendage closure (LAAC) caseload on cardiovascular outpatient and hospitalisation costs are limited. Methods: The present single-institution analysis includes patients treated consecutively from the beginning of our LAAC experience in January 2012 until December 2016. Pre- and post-LAAC costs for hospitalisation and ambulatory visits were included. Results: A total of 676 patients underwent percutaneous LAAC (using the Wa...
Abstract
Cited 17 times since 2022 (5.5 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 16, Issue 5, 28 4 2022, Pages 415-422
Coronary CTA plaque volume severity stages according to invasive coronary angiography and FFR.
Min JK, Chang HJ, Andreini D, Pontone G, Guglielmo M, Bax JJ, Knaapen P, Raman SV, Chazal RA, Freeman AM, Crabtree T, Earls JP
Background: Atherosclerotic plaque characterization by coronary computed tomography angiography (CCTA) enables quantification of coronary artery disease (CAD) burden and type, which has been demonstrated as the strongest discriminant of future risk of major adverse cardiac events (MACE). To date, there are no clinically useful thresholds to assist with understanding a patient's disease burden and guide diagnosis and management, as there exists with coronary artery calcium (CAC) scoring. The...
Abstract
Cited 23 times since 2022 (7.5 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 24, Issue 1, 28 4 2022, Pages 21
4D flow cardiovascular magnetic resonance derived energetics in the Fontan circulation correlate with exercise capacity and CMR-derived liver fibrosis/congestion.
Rijnberg FM, Westenberg JJM, van Assen HC, Juffermans JF, Kroft LJM, van den Boogaard PJ, Terol Espinosa de Los Monteros C, Warmerdam EG, Leiner T, Grotenhuis HB, Jongbloed MRM, Hazekamp MG, Roest AAW, Lamb HJ
Aim: This study explores the relationship between in vivo 4D flow cardiovascular magnetic resonance (CMR) derived blood flow energetics in the total cavopulmonary connection (TCPC), exercise capacity and CMR-derived liver fibrosis/congestion. Background: The Fontan circulation, in which both caval veins are directly connected with the pulmonary arteries (i.e. the TCPC) is the palliative approach for single ventricle patients. Blood flow efficiency in the TCPC has been associated with exercise ca...
Abstract
Radiology case reports,
Volume 17, Issue 5, 24 4 2022, Pages 1734-1736
Transmural ischemia visualized using routine Chest CTA.
van Driest FY, Hertgers O, Scholte AJHA, Jukema JW, de Graaf MA
Chest computed tomography (CT) is not routinely used for the diagnosis of myocardial infarction. However, there have been some reports of patients undergoing chest CT for other indications in which ultimately MI was diagnosed due to the presence of areas of myocardial hypoperfusion. The authors present the case of a 60-years old male who is referred due to acute chest pain radiating between the scapulae. Thoracic computed tomography angiography to rule out an aortic dissection revealed an occlus...
Abstract
