9393 results
Cited 9 times since 2021 (2.1 per year)
source: EuropePMC
Thrombosis journal,
Volume 19, Issue 1, 27 4 2021, Pages 45
Differential effect of statin use on coagulation markers: an active comparative analysis in the NEO study.
Bordbar M, de Mutsert R, Cevval M, Rosendaal FR, Jukema JW, Lijfering WM
Background: Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. This study aimed to compare pro-thrombotic activities of different classes of lipid-lowering drugs in an active comparator design and determine whether there is a relation between statin versus fibrate/niacin use and pro-coagulant factor outcomes. Methods: This is a cross-sectional analysis of participants from the Neth...
Abstract
Cited 11 times since 2021 (2.6 per year)
source: EuropePMC
Journal of neurology,
Volume 269, Issue 2, 26 4 2021, Pages 945-955
Clinical outcome of CIDP one year after start of treatment: a prospective cohort study.
Bus SRM, Broers MC, Lucke IM, Bunschoten C, van Lieverloo GGA, Adrichem ME, van Veen R, Wieske L, Lingsma HF, Goedee HS, van der Pol WL, van Schaik IN, Van Doorn PA, Jacobs BC, Eftimov F, ICOS Consortium
Objective: To assess clinical outcome in treatment-naive patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Methods: We included adult treatment-naive patients participating in the prospective International CIDP Outcome Study (ICOS) that fulfilled the European Federation of Neurological Societies/Peripheral Nerve Society (EFNS/PNS) diagnostic criteria for CIDP. Patients were grouped based on initial treatment with (1) intravenous immunoglobulin (IVIg), (2) corticoste...
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
International journal of cardiology. Heart & vasculature,
Volume 35, 25 4 2021, Pages 100830
Elevated resting heart rate is a marker of subclinical left ventricular dysfunction in hodgkin lymphoma survivors.
Heemelaar JC, Krol ADG, Louwerens M, L M A Beeres S, Holman ER, Schalij MJ, Louisa Antoni M
Background: Thoracic irradiation is one of the cornerstones of Hodgkin lymphoma (HL) treatment, which contributes to high rates of long-term survivorship, but begets a life-long increased risk of heart disease including heart failure. At the cardio-oncology (CO) clinic, persistent sinus tachycardia or elevated resting heart rate (RHR) is frequently observed in these patients. The aim of this study was to evaluate the relation between RHR and left ventricular (LV) dysfunction. Methods: In 75 HL s...
Abstract
Cited 13 times since 2021 (3.1 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 78, 25 4 2021, Pages 281-287
Assessment of Tissue Viability Following Amputation Surgery Using Near-Infrared Fluorescence Imaging With Indocyanine Green.
Van Den Hoven P, Van Den Berg SD, Van Der Valk JP, Van Der Krogt H, Van Doorn LP, Van De Bogt KEA, Van Schaik J, Schepers A, Vahrmeijer AL, Hamming JF, Van Der Vorst JR
Background: Patients with chronic limb threatening ischemia have a risk of undergoing a major amputation within 1 year of nearly 30% with a substantial risk of re-amputation since wound healing is often impaired. Quantitative assessment of regional tissue viability following amputation surgery can identify patients at risk for impaired wound healing. In quantification of regional tissue perfusion, near-infrared (NIR) fluorescence imaging using Indocyanine Green (ICG) seems promising. Methods: Th...
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 24 4 2021, Pages 668503
Computed Tomography Derived Coronary Triangulated Orifice Area-Deduction of a New Parameter for Follow-up After Surgical Correction of Anomalous Aortic Origin of Coronary Arteries and Call for Validation.
Meijer FMM, Kiès P, Verheijen DBH, Vliegen HW, Jongbloed MRM, Hazekamp MG, Lamb HJ, Egorova AD
Introduction: Anomalous aortic origin of a coronary artery (AAOCA) from the opposite sinus of Valsalva is a rare congenital abnormality. Computed tomography angiography (CTA) is primarily used as a diagnostic tool to evaluate the anatomy and identify potentially malignant AAOCA variants. Limited data is available on the role of CTA during postoperative follow-up. We aimed to develop an objective CTA derived parameter for diagnostic evaluation and follow-up after surgical correction of AAOCA and...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 37, Issue 11, 23 4 2021, Pages 3313-3322
Quantification of myocardial ischemia and subtended myocardial mass at adenosine stress cardiac computed tomography: a feasibility study.
van Driest FY, van der Geest RJ, Broersen A, Dijkstra J, El Mahdiui M, Jukema JW, Scholte AJHA
Combination of coronary computed tomography angiography (CCTA) and adenosine stress CT myocardial perfusion (CTP) allows for coronary artery lesion assessment as well as myocardial ischemia. However, myocardial ischemia on CTP is nowadays assessed semi-quantitatively by visual analysis. The aim of this study was to fully quantify myocardial ischemia and the subtended myocardial mass on CTP. We included 33 patients referred for a combined CCTA and adenosine stress CTP protocol, with good or excel...
Abstract
Cited 11 times since 2021 (2.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 153, 22 4 2021, Pages 30-35
Prevalence of Aortic Valve Stenosis in Patients With ST-Segment Elevation Myocardial Infarction and Effect on Long-Term Outcome.
Singh GK, van der Bijl P, Goedemans L, Vollema EM, Abou R, Ajmone Marsan N, Bax JJ, Delgado V
Several studies have shown an association between aortic valve stenosis (AS), atherosclerosis and cardiovascular risk factors. These risk factors are frequently encountered in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the prevalence and the prognostic implications of AS in patients presenting with STEMI. A total of 2041 patients (61 ± 12 years old, 76% male) admitted with STEMI and treated with primary percutaneous coronary interventi...
Abstract
Cited 24 times since 2021 (5.7 per year)
source: EuropePMC
BMC medicine,
Volume 19, Issue 1, 22 4 2021, Pages 139
Association of statin use in older people primary prevention group with risk of cardiovascular events and mortality: a systematic review and meta-analysis of observational studies.
Awad K, Mohammed M, Zaki MM, Abushouk AI, Lip GYH, Blaha MJ, Lavie CJ, Toth PP, Jukema JW, Sattar N, Banach M, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group and the International Lipid Expert Panel (ILEP)
Background: Current evidence from randomized controlled trials on statins for primary prevention of cardiovascular disease (CVD) in older people, especially those aged > 75 years, is still lacking. We conducted a systematic review and meta-analysis of observational studies to extend the current evidence about the association of statin use in older people primary prevention group with risk of CVD and mortality. Methods: PubMed, Scopus, and Embase were searched from inception until March 18, 20...
Abstract
Cited 7 times since 2021 (1.7 per year)
source: EuropePMC
Molecular cancer research : MCR,
Volume 19, Issue 10, 22 4 2021, Pages 1613-1621
Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.
Schepers A, Jochems F, Lieftink C, Wang L, Pogacar Z, Leite de Oliveira R, De Conti G, Beijersbergen RL, Bernards R
Pro-senescence therapies are increasingly being considered for the treatment of cancer. Identifying additional targets to induce senescence in cancer cells could further enable such therapies. However, screening for targets whose suppression induces senescence on a genome-wide scale is challenging, as senescent cells become growth arrested, and senescence-associated features can take 1 to 2 weeks to develop. For a screen with a whole-genome CRISPR library, this would result in billions of undesi...
Abstract
Cited 11 times since 2021 (2.6 per year)
source: EuropePMC
ESC heart failure,
Volume 8, Issue 5, 22 4 2021, Pages 3512-3520
Identification of sex-specific biomarkers predicting new-onset heart failure.
Raafs A, Verdonschot J, Ferreira JP, Wang P, Collier T, Henkens M, Björkman J, Boccanelli A, Clark AL, Delles C, Diez J, González A, Girerd N, Jukema JW, Pinet F, Rossignol P, Thum T, Vodovar N, de Boer RA, van Empel V, Staessen JA, Hazebroek M, Cleland J, Zannad F, Heymans S
Aims: Heart failure (HF) is common in both men and women, yet disease pathophysiology, presentation, and progression differ between sexes. Studies addressing whether biomarkers predict new onset HF sex-specifically are scarce. This study therefore aims to test the sex-specificity of 252 protein biomarkers for new-onset HF. Methods and results: A matched case-control design in patients selected from cohorts within the HOMAGE consortium was used. Cases (new-onset HF, n = 562) and controls (n = 780...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
The Journal of dermatological treatment,
Volume 33, Issue 4, 21 3 2021, Pages 1986-1989
Eczema control and treatment satisfaction in atopic dermatitis patients treated with dupilumab - a cross-sectional study from the BioDay registry.
Oosterhaven JAF, Spekhorst LS, Zhang J, Voorberg AN, Romeijn GLE, Boesjes CM, de Graaf M, de Bruin-Weller MS, Schuttelaar MLA
Background: Eczema control is a new construct to be measured in atopic dermatitis (AD). Objectives: Measuring patient-perceived eczema control and treatment satisfaction in AD patients, treated with dupilumab between 16 and 52 weeks. Methods: Cross-sectional questionnaire study. Patients from the Dutch BioDay registry completed the Atopic Dermatitis Control Test (ADCT), Recap of Atopic Eczema (RECAP) and Treatment Satisfaction Questionnaire for Medication, Version II (TSQM v. II), along with oth...
Abstract
Cited 6 times since 2021 (1.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 152, 20 3 2021, Pages 11-18
Prognostic Value of Multilayer Left Ventricular Global Longitudinal Strain in Patients with ST-segment Elevation Myocardial Infarction with Mildly Reduced Left Ventricular Ejection Fractions.
Abou R, Goedemans L, Montero-Cabezas JM, Prihadi EA, El Mahdiui M, Schalij MJ, Ajmone Marsan N, Bax JJ, Delgado V
Multilayer (epi-, mid- and endocardium) left ventricular (LV) global longitudinal strain (GLS) reflects the extent of myocardial damage after ST-segment myocardial infarction (STEMI). However, the prognostic implications of multilayer LV GLS remain unclear. We studied the association between multilayer LV GLS and prognosis in patients with mildly reduced or preserved LV ejection fraction (EF) after STEMI. Patients with first STEMI and LVEF>45% were evaluated retrospectively. Baseline multilay...
Abstract
Cited 11 times since 2021 (2.6 per year)
source: EuropePMC
Scientific reports,
Volume 11, Issue 1, 18 3 2021, Pages 12899
Lipid biomarkers in statin users with coronary artery disease annotated by coronary computed tomography angiography.
Michelucci E, Giorgi ND, Finamore F, Smit JM, Scholte AJHA, Signore G, Rocchiccioli S
Molecular markers are suggested to improve the diagnostic and prognostic accuracy in patients with coronary artery disease (CAD) beyond current clinical scores based on age, gender, symptoms and traditional risk factors. In this context, plasma lipids are emerging as predictors of both plaque composition and risk of future events. We aim to identify plasma lipid biomarkers associated to CAD indexes of stenosis severity, plaque lipid content and a comprensive score of CAD extent and its risk. We...
Abstract
Cited 61 times since 2021 (14.4 per year)
source: EuropePMC
Nature communications,
Volume 12, Issue 1, 18 3 2021, Pages 3799
Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions.
Schaedel L, Lorenz C, Schepers AV, Klumpp S, Köster S
The cytoskeleton determines cell mechanics and lies at the heart of important cellular functions. Growing evidence suggests that the manifold tasks of the cytoskeleton rely on the interactions between its filamentous components-actin filaments, intermediate filaments, and microtubules. However, the nature of these interactions and their impact on cytoskeletal dynamics are largely unknown. Here, we show in a reconstituted in vitro system that vimentin intermediate filaments stabilize microtubules...
Abstract
Cited 32 times since 2021 (7.5 per year)
source: EuropePMC
Diabetes care,
Volume 44, Issue 8, 18 3 2021, Pages 1757-1765
Serum Magnesium Is Inversely Associated With Heart Failure, Atrial Fibrillation, and Microvascular Complications in Type 2 Diabetes.
Oost LJ, van der Heijden AAWA, Vermeulen EA, Bos C, Elders PJM, Slieker RC, Kurstjens S, van Berkel M, Hoenderop JGJ, Tack CJ, Beulens JWJ, de Baaij JHF
Objective: We investigated whether serum magnesium (Mg2+) was prospectively associated with macro- or microvascular complications and mediated by glycemic control (hemoglobin A1c [HbA1c]), in type 2 diabetes (T2D). Research design and methods: We analyzed in 4,348 participants the association of serum Mg2+ with macrovascular disease and mortality (acute myocardial infarction [AMI], coronary heart disease [CHD], heart failure [HF], cerebrovascular accident [CVA], and peripheral arterial disease [...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
Journal of dairy science,
Volume 104, Issue 9, 17 3 2021, Pages 10217-10231
The effect of new bovine viral diarrhea virus introduction on somatic cell count, calving interval, culling, and calf mortality of dairy herds in the Dutch bovine viral diarrhea virus-free program.
Yue X, van der Voort M, Steeneveld W, van Schaik G, Vernooij JCM, van Duijn L, Hogeveen H
Bovine viral diarrhea virus (BVDV) infection has a major effect on the health of cows and consequently on herd performance. Many countries have implemented control or eradication programs to mitigate BVDV infection and its negative effects. These negative effects of BVDV infection on dairy herds are well documented, but there is much less information about the effects of new introduction of BVDV on dairy herds already participating in a BVDV control program. The objective of our study was to inv...
Abstract
Cited 4 times since 2021 (0.9 per year)
source: EuropePMC
Antimicrobial agents and chemotherapy,
Volume 65, Issue 7, 17 3 2021, Pages e0075421
Erratum for Janssen et al., "Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics".
Janssen AB, Doorduijn DJ, Mills G, Rogers MRC, Bonten MJM, Rooijakkers SHM, Willems RJL, Bengoechea JA, van Schaik W
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
ACS omega,
Volume 6, Issue 25, 16 3 2021, Pages 16649-16660
Comparative Study: Impacts of Ca and Mg Salts on Iron Oxygen Carriers in Chemical Looping Combustion of Biomass.
Yilmaz D, Steenari BM, Leion H
Chemical looping combustion (CLC) is one of the most promising methods for carbon capture and storage (CCS). An oxygen carrier, i.e., a mineral that can be oxidized and reduced, is used to convert the fuel in the process. The produced CO2 is inherently separated from the air components that enables easier CCS. The use of biomass-based fuels is desirable since it can lead to negative CO2 emissions. On the other hand, alkali compounds from the biomass may interact with the oxygen carrier causing p...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
AJR. American journal of roentgenology,
Volume 217, Issue 6, 16 3 2021, Pages 1344-1352
Impact of Dose Reduction Strategies on Image Quality of Coronary CTA in Real-World Clinical Practice: A Subanalysis of PROTECTION VI Registry Data.
Stocker TJ, Nühlen N, Schmermund A, Leipsic J, Grove EL, Deseive S, Bax JJ, Maurovich-Horvat P, Otton J, Hadamitzky M, Chen MY, Naoum C, Andreini D, Rubinshtein R, Massberg S, Hausleiter J
BACKGROUND. Dose reduction strategies for coronary CTA (CCTA) have been underused in clinical practice given concern that the strategies may lower image quality. OBJECTIVE. The purpose of this study was to explore associations between dose reduction strategies and CCTA image quality in real-world clinical practice. METHODS. This subanalysis of the international Prospective Multicenter Registry on Radiation Dose Estimates of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI) study i...
Abstract
Cited 12 times since 2021 (2.8 per year)
source: EuropePMC
Frontiers in public health,
Volume 9, 16 3 2021, Pages 568822
Creating a Social Learning Environment for and by Older Adults in the Use and Adoption of Smartphone Technology to Age in Place.
den Haan M, Brankaert R, Kenning G, Lu Y
Smartphone technologies can support older adults in their daily lives as they age in place at home. However, they may struggle to use these technologies which impacts acceptance, adoption, and sustainable use. Peer to peer community learning has the potential to support older adults to learn using (smartphone) technologies. This paper studies such a learning community approach and how it can support older adults to learn using and adopt the smartphone application GoLivePhone. This technology ass...
Abstract
