7301 results
Cited 18 times since 2002 (0.8 per year)
source: EuropePMC
The New England journal of medicine,
Volume 347, Issue 22, 1 1 2002, Pages 1803-4; author reply 1803-4
Cardiac resynchronization therapy for heart failure.
Bax JJ, Van der Wall EE, Schalij MJ
Abstract
Cited 38 times since 2002 (1.7 per year)
source: EuropePMC
Journal of virology,
Volume 76, Issue 21, 1 1 2002, Pages 10829-10840
Characterization of two new structural glycoproteins, GP(3) and GP(4), of equine arteritis virus.
Wieringa R, de Vries AA, Raamsman MJ, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-stranded RNA virus belonging to the family Arteriviridae of the order Nidovirales. Four envelope proteins have hitherto been identified in EAV particles: the predominant membrane proteins M and G(L), the unglycosylated small envelope protein E, and the nonabundant membrane glycoprotein G(S). In this study, we established that the products of EAV open reading frame 3 (ORF3) and ORF4 (designated GP(3) and GP(4), respectively) are also minor st...
Abstract
Cited 27 times since 2002 (1.2 per year)
source: EuropePMC
American heart journal,
Volume 144, Issue 5, 1 1 2002, Pages 865-869
Assessment of residual myocardial viability in regions with chronic electrocardiographic Q-wave infarction.
Schinkel AF, Bax JJ, Boersma E, Elhendy A, Vourvouri EC, Roelandt JR, Poldermans D
Background: Q waves on the electrocardiogram are often considered to be reflective of irreversibly scarred myocardium due to antecedent transmural myocardial infarction. However, there are some indications that residual viable tissue may be present in Q-wave-infarcted regions. It is clinically relevant to know how many Q-wave regions contain viable tissue because these patients may benefit from revascularization in terms of improvement of function and long-term survival. Methods: Patients (n = 1...
Abstract
Cited 20 times since 2002 (0.9 per year)
source: EuropePMC
Journal of virology,
Volume 76, Issue 21, 1 1 2002, Pages 10734-10744
Efficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors.
Gonçalves MA, van der Velde I, Janssen JM, Maassen BT, Heemskerk EH, Opstelten DJ, Knaän-Shanzer S, Valerio D, de Vries AA
Effective gene therapy is dependent on safe gene delivery vehicles that can achieve efficient transduction and sustained transgene expression. We are developing a hybrid viral vector system that combines in a single particle the large cloning capacity and efficient cell cycle-independent nuclear gene delivery of adenovirus (Ad) vectors with the long-term transgene expression and lack of viral genes of adeno-associated virus (AAV) vectors. The strategy being pursued relies on coupling the AAV DNA...
Abstract
Cited 5 times since 2002 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 9, Issue 6, 1 1 2002, Pages 587-593
Safety and feasibility of cardiac FDG SPECT following oral administration of Acipimox, a nicotinic acid derivative: Comparison of image quality with hyperinsulinemic euglycemic clamping in nondiabetic patients.
Bax JJ, Visser FC, Poldermans D, Van Lingen A, Elhendy A, Boersma E, Sloof GW, Visser CA
Background: Image quality of cardiac fluorine-18-deoxyglucose (FDG) studies is highly dependent on the metabolic conditions during the study; hyperinsulinemic euglycemic clamping ensures adequate image quality. However, the approach is time-consuming. Data in a small number of patients suggest that oral administration of a nicotinic acid derivative (Acipimox, 250 mg; Byk, The Netherlands) results in good image quality. Methods and results: The safety and image quality of cardiac FDG single photo...
Abstract
Cited 4 times since 2002 (0.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 22, Issue 5, 1 1 2002, Pages 802-807
Structural degeneration of pulmonary homografts used as aortic valve substitute underlines early graft failure.
Koolbergen DR, Hazekamp MG, de Heer E, van Hoorn F, Huysmans HA, Bruijn JA, Dion RA
Objectives: The limited availability of donor valves and experimental evidence that pulmonary valves can withstand systemic pressure made us use cryopreserved pulmonary homografts as aortic valve substitutes. We observed a high incidence of early reoperation because of severe graft insufficiency due to cuspal tears. The mid-term results are evaluated in this study and histological analysis of explanted homografts is performed to investigate the cause of graft failure. Methods: From December 1991...
Abstract
Cited 75 times since 2002 (3.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 90, Issue 10, 1 1 2002, Pages 1157-1160
Usefulness of dynamic multislice computed tomography of left ventricular function in unstable angina pectoris and comparison with echocardiography.
Dirksen MS, Bax JJ, de Roos A, Jukema JW, van der Geest RJ, Geleijns K, Boersma E, van der Wall EE, Lamb HJ
Abstract
Cited 49 times since 2002 (2.2 per year)
source: EuropePMC
Circulation research,
Volume 91, Issue 7, 1 1 2002, Pages 577-584
Accelerated atherosclerosis and calcification in vein grafts: a study in APOE*3 Leiden transgenic mice.
Lardenoye JH, de Vries MR, Löwik CW, Xu Q, Dhore CR, Cleutjens JP, van Hinsbergh VW, van Bockel JH, Quax PH
Vein grafts fail due to development of intimal hyperplasia and accelerated atherosclerosis. Many murine genetic models in which genes are overexpressed, deleted, or mutated have been introduced recently. Therefore, mouse models are very well suited to dissect the relative contribution of different genes in the development of accelerated atherosclerosis. In the present study, we evaluated whether accelerated atherosclerosis in human vein grafts could be mimicked in hypercholesterolemic APOE*3 Lei...
Abstract
Cited 4 times since 2002 (0.2 per year)
source: EuropePMC
Circulation,
Volume 106, Issue 14, 1 1 2002, Pages 1881-1882
Images in cardiovascular medicine. Malignant right coronary artery anomaly detected by magnetic resonance coronary angiography.
Dirksen MS, Langerak SE, de Roos A, Vliegen HW, Jukema JW, Bax JJ, Wielopolski PA, van der Wall EE, Lamb HJ
Abstract
Cited 52 times since 2002 (2.3 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 124, Issue 4, 1 1 2002, Pages 689-697
The pathology of fresh and cryopreserved homograft heart valves: an analysis of forty explanted homograft valves.
Koolbergen DR, Hazekamp MG, de Heer E, Bruggemans EF, Huysmans HA, Dion RA, Bruijn JA
Objective: Tissue degeneration reduces the durability of aortic and pulmonary homograft heart valves. Homograft valves can evoke cellular and humoral immune responses that might be detrimental to the valve tissue. Analyzing explanted homograft valves helps in understanding the different factors that eventually lead to tissue degeneration. Methods: A total of 40 homografts was acquired from patients whose grafts had been explanted because of stenosis (n = 22), insufficiency (n = 8), paravalvular...
Abstract
Cited 6 times since 2002 (0.3 per year)
source: EuropePMC
Cardiology in the young,
Volume 12, Issue 5, 1 1 2002, Pages 474-478
The need for cardiac follow-up in adults with mild congenital cardiac disease.
Kamphuis M, Vliegen HW, Vogels T, Zwinderman KH, van der Wall EE, Verloove-Vanhorick SP, Ottenkamp J
Objective: To discuss the need for continuing cardiac surveillance in adults with hemodynamically insignificant congenital cardiac disease. Methods: In 82 patients with mild congenital cardiac malformations, aged from 17 to 32 years, we investigated the subjective health status, the health-related quality of life, any difficulties encountered in daily life, the regularity of follow-up, current diagnosis, and antibiotic prophylaxis. Results: The subjective health status, and the health-related qu...
Abstract
Cited 167 times since 2002 (7.4 per year)
source: EuropePMC
Circulation,
Volume 106, Issue 15, 1 1 2002, Pages 1985-1990
In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions.
Vink A, Schoneveld AH, van der Meer JJ, van Middelaar BJ, Sluijter JP, Smeets MB, Quax PH, Lim SK, Borst C, Pasterkamp G, de Kleijn DP
Background: Inflammation plays an important role in atherogenesis. The toll-like receptor 4 (TLR4) is the receptor for bacterial lipopolysaccharides and also recognizes cellular fibronectin and heat shock protein 60, endogenous peptides that are produced in response to tissue injury. To explore a possible role for this receptor in arterial obstructive disease, we determined the expression of TLR4 in the atherosclerotic arterial wall, including adventitia, and studied the effect of adventitial TL...
Abstract
The international journal of cardiovascular imaging,
Volume 18, Issue 5, 1 1 2002, Pages 353-355
The cavity-to-myocardial count ratio as a marker of left ventricular function.
Bax JJ, Lamb HJ, van der Wall EE
Abstract
Cited 3 times since 2002 (0.1 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 15, Issue 10 Pt 2, 1 1 2002, Pages 1285-1289
Stress echocardiography for risk stratification of patients with chest pain and normal or slightly narrowed coronary arteries.
Bigi R, Cortigiani L, Bax JJ, Colombo P, Desideri A, Sponzilli C, Fiorentini C
One hundred twenty-five patients (60 +/- 10 years old, 60 women) with known (35, previous myocardial infarction) or suspected (90) coronary artery disease (CAD) and no more than 50% coronary stenoses underwent pharmacologic (48 dipyridamole and 77 dobutamine) stress echocardiography (SE) and prospective follow-up (36 +/- 22 months) for cardiac death, nonfatal infarction, and unstable angina. The ability of clinical and SE variables to predict the outcome was assessed by the Cox model. A signific...
Abstract
Cited 96 times since 2002 (4.2 per year)
source: EuropePMC
Blood,
Volume 101, Issue 5, 19 3 2002, Pages 1810-1817
Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
Collen A, Hanemaaijer R, Lupu F, Quax PH, van Lent N, Grimbergen J, Peters E, Koolwijk P, van Hinsbergh VW
Adult angiogenesis, associated with pathologic conditions, is often accompanied by the formation of a fibrinous exudate. This temporary matrix consists mainly of fibrin but is intermingled with plasma proteins and collagen fibers. The formation of capillary structures in a fibrinous matrix in vivo was mimicked by an in vitro model, in which human microvascular endothelial cells (hMVECs) seeded on top of a fibrin-10% collagen matrix form capillarylike tubular structures after stimulation with bas...
Abstract
Cited 32 times since 2002 (1.4 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 284, Issue 1, 12 2 2002, Pages H350-7
Impact of pericardial restraint on right atrial mechanics during acute right ventricular pressure load.
Maniar HS, Prasad SM, Gaynor SL, Chu CM, Steendijk P, Moon MR
Optimization of right atrial (RA) mechanics is important for maintaining right ventricular (RV) filling and global cardiac output. However, the impact of pericardial restraint on RA function and the compensatory role of the right atrium to changes in RV afterload remain poorly characterized. In eight open-chest sheep, RA elastance (contractility) and chamber stiffness were measured (RA pressure-volume relations) at baseline and during partial pulmonary artery (PA) occlusion. Data were collected...
Abstract
Cited 17 times since 2002 (0.7 per year)
source: EuropePMC
Atherosclerosis,
Volume 164, Issue 1, 1 1 2002, Pages 65-71
Raman spectroscopic investigation of atorvastatin, amlodipine, and both on atherosclerotic plaque development in APOE*3 Leiden transgenic mice.
van de Poll SW, Delsing DJ, Jukema JW, Princen HM, Havekes LM, Puppels GJ, van der Laarse A
Raman spectroscopy allows quantitative, non-destructive evaluation of entire, intact atherosclerotic plaques. We quantified the anti-atherosclerotic effects of atorvastatin and amlodipine on progression of atherosclerosis using post-mortem Raman spectroscopic plaque imaging in 28 APOE*3 Leiden transgenic mice who were fed a high fat/high cholesterol diet for 28 weeks. Mice were assigned to a control group receiving the diet alone or to groups that received the diet with either 0.01% w/w atorvast...
Abstract
Cited 36 times since 2002 (1.6 per year)
source: EuropePMC
Cardiovascular research,
Volume 55, Issue 4, 1 1 2002, Pages 768-777
Angiogenesis-independent cardioprotection in FGF-1 transgenic mice.
Buehler A, Martire A, Strohm C, Wolfram S, Fernandez B, Palmen M, Wehrens XH, Doevendans PA, Franz WM, Schaper W, Zimmermann R
Objective: This study was performed to evaluate the cardioprotective role of acidic fibroblast growth factor-1 (FGF-1) in transgenic mice with cardiac-specific overexpression of human FGF-1. Methods: Mice were subjected to coronary artery occlusion for 15-75 min with a continuously recorded 3-lead electrocardiogram (ECG). Infarct size was measured and ERK-1 and -2 activity was assessed by Western blot analysis. Creatine kinase and lactate dehydrogenase activity as marker for cell viability were...
Abstract
Cited 26 times since 2002 (1.1 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 22, Issue 9, 1 1 2002, Pages 1433-1438
Inhibition of accelerated atherosclerosis in vein grafts by placement of external stent in apoE*3-Leiden transgenic mice.
Lardenoye JH, De Vries MR, Grimbergen JM, Havekes LM, Knaapen MW, Kockx MM, van Hinsbergh VW, van Bockel JH, Quax PH
Objective: Vein grafts fail because of the development of intimal hyperplasia and accelerated atherosclerosis. Placement of an external stent around vein grafts resulted in an inhibition of intimal hyperplasia in several animal studies. Here, we assess the effects of external stenting on accelerated atherosclerosis in early vein grafts in carotid arteries in hypercholesterolemic apolipoprotein E*3-Leiden transgenic mice. Methods and results: Venous interposition grafting was performed in apolipo...
Abstract
Cited 20 times since 2002 (0.9 per year)
source: EuropePMC
Diabetes care,
Volume 25, Issue 9, 1 1 2002, Pages 1637-1643
Prognostic value of dobutamine-atropine stress myocardial perfusion imaging in patients with diabetes.
Schinkel AF, Elhendy A, van Domburg RT, Bax JJ, Vourvouri EC, Sozzi FB, Valkema R, Roelandt JR, Poldermans D
Objective: Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. Research design and methods: A total of 207 consecutive diabetic patients who were unable to undergo exercise stress testing underwent dobutamine-atropine stress myocardial perfusion imaging. Follow-up was successful in 206 of 207 (99.5...
Abstract
