Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 12 times since 2017 (1.5 per year) source: EuropePMC
Journal of clinical research in pediatric endocrinology, Volume 9, Issue 4, 7 1 2017, Pages 366-370 Successful Growth Hormone Therapy in Cornelia de Lange Syndrome. de Graaf M, Kant SG, Wit JM, Willem Redeker EJ, Eduard Santen GW, Henriëtta Verkerk AJM, Uitterlinden AG, Losekoot M, Oostdijk W
Cornelia de Lange syndrome (CdLS) is a both clinically and genetically heterogeneous syndrome. In its classical form, it is characterised by distinctive facial features, intra-uterine growth retardation, short stature, developmental delay, and anomalies in multiple organ systems. NIPBL, SMC1A, SMC3, RAD21 and HDAC8, all involved in the cohesin pathway, have been identified to cause CdLS. Growth hormone (GH) secretion has been reported as normal, and to our knowledge, there are no reports on the... Abstract
Cited 8 times since 2017 (1 per year) source: EuropePMC
Pain management nursing : official journal of the American Society of Pain Management Nurses, Volume 18, Issue 4, 7 1 2017, Pages 260-267 Effect of the Use of Buzzy<sup>®</sup> during Phlebotomy on Pain and Individual Satisfaction in Blood Donors. Yılmaz D, Heper Y, Gözler L
Phlebotomy causes pain and discomfort to adults. The objective of this study was to investigate the effect of the use of Buzzy® on phlebotomy satisfaction and pain relating to the phlebotomy process in healthy adult blood donors voluntarily donating blood. This was a prospective, randomized, controlled experimental study. The research sample was made up of 90 healthy adult men. These individuals were randomly assigned to an experimental group (Buzzy group), a placebo control group, and a noninte... Abstract
Cited 54 times since 2017 (6.6 per year) source: EuropePMC
BMJ open, Volume 7, Issue 5, 6 1 2017, Pages e015599 The Hoorn Diabetes Care System (DCS) cohort. A prospective cohort of persons with type 2 diabetes treated in primary care in the Netherlands. van der Heijden AA, Rauh SP, Dekker JM, Beulens JW, Elders P, 't Hart LM, Rutters F, van Leeuwen N, Nijpels G
Purpose: People with type 2 diabetes (T2D) have a doubled morbidity and mortality risk compared with persons with normal glucose tolerance. Despite treatment, clinical targets for cardiovascular risk factors are not achieved. The Hoorn Diabetes Care System cohort (DCS) is a prospective cohort representing a comprehensive dataset on the natural course of T2D, with repeated clinical measures and outcomes. In this paper, we describe the design of the DCS cohort. Participants: The DCS consists of pe... Abstract
Cited 7 times since 2017 (0.9 per year) source: EuropePMC
International journal of cardiology, Volume 243, 2 1 2017, Pages 191-193 Clinical course of tricuspid regurgitation in repaired tetralogy of Fallot. Woudstra OI, Bokma JP, Winter MM, Kiès P, Jongbloed MRM, Vliegen HW, Groenink M, Meijboom FJ, Mulder BJM, Bouma BJ
Background: Little is known on the clinical course of tricuspid regurgitation (TR) in patients with repaired tetralogy of Fallot (rTOF) and which patients are at particular risk. This study aims to determine TR course, characteristics associated with TR progression, and the prognostic relevance of TR in rTOF patients. Methods: In this dualcenter cohort study, rTOF patients from a prospective national registry with ≥1 cardiac magnetic resonance imaging study and ≥2 echocardiograms available were... Abstract
Cited 42 times since 2017 (5.1 per year) source: EuropePMC
JAMA cardiology, Volume 2, Issue 6, 1 1 2017, Pages 678-683 Value of Cardiovascular Magnetic Resonance Imaging in Noninvasive Risk Stratification in Tetralogy of Fallot. Bokma JP, de Wilde KC, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Zwinderman AH, Groenink M, Mulder BJM, Bouma BJ
Importance: Adults late after total correction of tetralogy of Fallot (TOF) are at risk for major complications. Cardiovascular magnetic resonance (CMR) imaging is recommended to quantify right ventricular (RV) and left ventricular (LV) function. However, a commonly used risk model by Khairy et al requires invasive investigations and lacks CMR imaging to identify high-risk patients. Objective: To implement CMR imaging in noninvasive risk stratification to predict major adverse clinical outcomes.... Abstract
Cited 28 times since 2017 (3.4 per year) source: EuropePMC
Human molecular genetics, Volume 26, Issue 12, 1 1 2017, Pages 2346-2363 Discovery of novel heart rate-associated loci using the Exome Chip. van den Berg ME, Warren HR, Cabrera CP, Verweij N, Mifsud B, Haessler J, Bihlmeyer NA, Fu YP, Weiss S, Lin HJ, Grarup N, Li-Gao R, Pistis G, Shah N, Brody JA, Müller-Nurasyid M, Lin H, Mei H, Smith AV, Lyytikäinen LP, Hall LM, van Setten J, Trompet S, Prins BP, Isaacs A, Radmanesh F, Marten J, Entwistle A, Kors JA, Silva CT, Alonso A, Bis JC, de Boer R, de Haan HG, de Mutsert R, Dedoussis G, Dominiczak AF, Doney ASF, Ellinor PT, Eppinga RN, Felix SB, Guo X, Hagemeijer Y, Hansen T, Harris TB, Heckbert SR, Huang PL, Hwang SJ, Kähönen M, Kanters JK, Kolcic I, Launer LJ, Li M, Yao J, Linneberg A, Liu S, Macfarlane PW, Mangino M, Morris AD, Mulas A, Murray AD, Nelson CP, Orrú M, Padmanabhan S, Peters A, Porteous DJ, Poulter N, Psaty BM, Qi L, Raitakari OT, Rivadeneira F, Roselli C, Rudan I, Sattar N, Sever P, Sinner MF, Soliman EZ, Spector TD, Stanton AV, Stirrups KE, Taylor KD, Tobin MD, Uitterlinden A, Vaartjes I, Hoes AW, van der Meer P, Völker U, Waldenberger M, Xie Z, Zoledziewska M, Tinker A, Polasek O, Rosa
Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explained 0.9% of the variation. This study aims to discover new genetic loci associated with heart rate from Exome Chip meta-analyses.Heart rate was measured from either elecrtrocardiograms or pulse recordings. We meta-analysed heart rate association resul... Abstract
Cited 10 times since 2017 (1.2 per year) source: EuropePMC
Acta dermato-venereologica, Volume 97, Issue 6, 1 1 2017, Pages 724-730 Risk of Non-melanoma Skin Cancer in Patients with Atopic Dermatitis Treated with Oral Immunosuppressive Drugs. Garritsen FM, van der Schaft J, van den Reek JM, Politiek K, van Os-Medendorp H, van Dijk M, Hijnen DJ, de Graaf M, Bruijnzeel-Koomen CA, de Jong EM, Schuttelaar MA, Bruin-Weller MS
There is uncertainty about the risk of developing non-melanoma skin cancer (NMSC), including basal cell carcinoma and squamous cell carcinoma (SCC), in patients with atopic dermatitis (AD) treated with oral immunosuppressive drugs. A total of 557 patients with AD treated with these drugs in the University Medical Center Utrecht and Groningen, the Netherlands, were analysed. NMSC after oral immunosuppressive treatment was reported in 18 patients (3.2%). The standardized incidence ratio for develo... Abstract
Cited 44 times since 2017 (5.4 per year) source: EuropePMC
Critical care medicine, Volume 45, Issue 6, 1 1 2017, Pages 972-979 Increased Early Systemic Inflammation in ICU-Acquired Weakness; A Prospective Observational Cohort Study. Witteveen E, Wieske L, van der Poll T, van der Schaaf M, van Schaik IN, Schultz MJ, Verhamme C, Horn J, Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium
Objectives: To investigate whether patients who develop ICU-acquired weakness have a different pattern of systemic inflammatory markers compared with critically ill patients who do not develop ICU-acquired weakness. Design: Prospective observational cohort study. Setting: Mixed medical-surgical ICU of a tertiary care hospital in the Netherlands. Patients: Newly admitted critically ill patients, greater than or equal to 48 hours on mechanical ventilation with a nonneurologic ICU admission diagnos... Abstract
Diagnosis (Berlin, Germany), Volume 4, Issue 2, 1 1 2017, Pages 93-99 Identifying error types in visual diagnostic skill assessment. Ravesloot CJ, van der Gijp A, van der Schaaf MF, Huige JCBM, Ten Cate O, Vincken KL, Mol CP, van Schaik JPJ
Background: Misinterpretation of medical images is an important source of diagnostic error. Errors can occur in different phases of the diagnostic process. Insight in the error types made by learners is crucial for training and giving effective feedback. Most diagnostic skill tests however penalize diagnostic mistakes without an eye for the diagnostic process and the type of error. A radiology test with stepwise reasoning questions was used to distinguish error types in the visual diagnostic pro... Abstract
Cited 12 times since 2017 (1.5 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 51, Issue 6, 1 1 2017, Pages 1100-1107 Extensive infective endocarditis of the aortic root and the aortic-mitral continuity: a mitral valve sparing approach†. Tomšic A, Schneider AW, Palmen M, van Brakel TJ, Versteegh MIM, Klautz RJM
Objectives: Severe cases of infective endocarditis (IE) of the aortic valve can cause aortic root destruction and affect the surrounding structures, including the aortic-mitral continuity, the anterior mitral valve leaflet and the roof of the left atrium. Reconstruction after resection of all infected tissue remains challenging. We describe our surgical approach and the mid-term results. Methods: Between January 2004 and December 2015, 35 patients underwent surgery for extensive IE of the aortic... Abstract
Cited 15 times since 2017 (1.8 per year) source: EuropePMC
European heart journal, Volume 38, Issue 21, 1 1 2017, Pages 1632-1637 Improving public health by improving clinical trial guidelines and their application. Landray MJ, Bax JJ, Alliot L, Buyse M, Cohen A, Collins R, Hindricks G, James SK, Lane S, Maggioni AP, Meeker-O'Connell A, Olsson G, Pocock SJ, Rawlins M, Sellors J, Shinagawa K, Sipido KR, Smeeth L, Stephens R, Stewart MW, Stough WG, Sweeney F, Van de Werf F, Woods K, Casadei B
Evidence generated from randomized controlled trials forms the foundation of cardiovascular therapeutics and has led to the adoption of numerous drugs and devices that prolong survival and reduce morbidity, as well as the avoidance of interventions that have been shown to be ineffective or even unsafe. Many aspects of cardiovascular research have evolved considerably since the first randomized trials in cardiology were conducted. In order to be large enough to provide reliable evidence about eff... Abstract
Cited 1 times since 2017 (0.1 per year) source: EuropePMC
Radiology, Volume 285, Issue 1, 29 5 2017, Pages 73-82 Is Hepatic Triglyceride Content Associated with Aortic Pulse Wave Velocity and Carotid Intima-Media Thickness? The Netherlands Epidemiology of Obesity Study. Widya RL, de Mutsert R, Westenberg JJM, Gast KB, den Heijer M, le Cessie S, Smit JWA, Jukema JW, Rosendaal FR, de Roos A, Lamb HJ, NEO Study Group
Purpose To test the hypothesis that hepatic triglyceride content is associated with subclinical vascular impairment and is not confounded by various cardiometabolic risk factors. Materials and Methods This study was approved by the institutional review board, and all participants gave written informed consent. In this cross-sectional analysis of baseline measurements of the Netherlands Epidemiology of Obesity study, a population-based cohort study, 1899 participants (52% men; mean age, 55 years... Abstract
Cited 69 times since 2017 (8.4 per year) source: EuropePMC
The lancet. Diabetes & endocrinology, Volume 5, Issue 7, 26 4 2017, Pages 534-543 Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, Laufs U, Werner C, Koenig W, Rothenbacher D, Mons U, Breitling LP, Brenner H, Jennings RT, Petrakis I, Triem S, Klug M, Filips A, Blankenberg S, Waldeyer C, Sinning C, Schnabel RB, Lackner KJ, Vlachopoulou E, Nygård O, Svingen GFT, Pedersen ER, Tell GS, Sinisalo J, Nieminen MS, Laaksonen R, Trompet S, Smit RAJ, Sattar N, Jukema JW, Groesdonk HV, Delgado G, Stojakovic T, Pilbrow AP, Cameron VA, Richards AM, Doughty RN, Gong Y, Cooper-DeHoff R, Johnson J, Scholz M, Beutner F, Thiery J, Smith JG, Vilmundarson RO, McPherson R, Stewart AFR, Cresci S, Lenzini PA, Spertus JA, Olivieri O, Girelli D, Martinelli NI, Leiherer A, Saely CH, Drexel H, Mündlein A, Braund PS, Nelson CP, Samani NJ, Kofink D, Hoefer IE, Pasterkamp G, Quyyumi AA, Ko YA, Hartiala JA, Allayee H, Tang WHW, Hazen SL, Eriksson N, Held C, Hagström E, Wallentin L, Åkerblom A, Siegbahn A, Karp I, Labos C, Pilote L, Engert JC, Brophy JM, Thanassoulis G, Bogaty P, Szczeklik W, Kaczor M,
Background: Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coronary heart disease remains less clear. Methods: We obtained data from 3313 patients with established coronary heart disease in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. We tested associations of tertiles of lipoprotein(a) concentration i... Abstract
Cited 3 times since 2017 (0.4 per year) source: EuropePMC
Trials, Volume 18, Issue 1, 26 4 2017, Pages 243 The effects of a psychological intervention directed at optimizing immune function: study protocol for a randomized controlled trial. Schakel L, Veldhuijzen DS, van Middendorp H, Prins C, Joosten SA, Ottenhoff THM, Visser LG, Evers AWM
Background: Previous research has provided evidence for the link between psychological processes and psychophysiological health outcomes. Psychological interventions, such as face-to-face or online cognitive behavioral therapy (CBT) and serious games aimed at improving health, have shown promising results in promoting health outcomes. Few studies so far, however, have examined whether Internet-based CBT combined with serious gaming elements is effective in modulating health outcomes. Moreover, s... Abstract
Cited 11 times since 2017 (1.3 per year) source: EuropePMC
European journal of preventive cardiology, Volume 24, Issue 12, 25 4 2017, Pages 1319-1327 Chance of surgery in adult congenital heart disease. Verheugt CL, Uiterwaal CS, Vaartjes I, van der Velde ET, Zomer AC, Meijboom FJ, Pieper PG, Post MC, Vliegen HW, Hazekamp MG, Grobbee DE, Mulder BJ
Background Young patients with congenital heart disease reaching adulthood face mandatory transition to adult cardiology. Their new cardiologist needs to assess the chances of major future events such as surgery. Using a large national registry, we assessed if patient characteristics at the age of 18 years could predict the chance of congenital heart surgery in adulthood. Design and methods Of 10,300 patients from the CONCOR national registry, we used general patient characteristics at age 18 ye... Abstract
Cited 20 times since 2017 (2.4 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 33, Issue 11, 25 4 2017, Pages 1753-1759 Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping. van Dijk R, Kuijpers D, Kaandorp TAM, van Dijkman PRM, Vliegenthart R, van der Harst P, Oudkerk M
The antagonistic effects of caffeine on adenosine receptors are a possible cause of false-negative stress perfusion imaging. The purpose of this study was to determine the effects of coffee intake Abstract
Cited 9 times since 2017 (1.1 per year) source: EuropePMC
Frontiers in psychology, Volume 8, 24 4 2017, Pages 808 Commentary: The Social Dilemma of Autonomous Vehicles. Martin R, Kusev I, Cooke AJ, Baranova V, Van Schaik P, Kusev P
Cited 8 times since 2017 (1 per year) source: EuropePMC
Diabetology & metabolic syndrome, Volume 9, 22 4 2017, Pages 40 Association of metabolic syndrome and electrocardiographic markers of subclinical cardiovascular disease. Elffers TW, de Mutsert R, Lamb HJ, Maan AC, Macfarlane PW, Willems van Dijk K, Rosendaal FR, Jukema JW, Trompet S
Background: The metabolic syndrome (MetS) and its components are well-established risk factors for cardiovascular diseases (CVD). It is inconclusive whether MetS and MetS score are associated with electrocardiographic markers of subclinical CVD, therefore we investigated this in a population without pre-existing CVD. Methods: We performed a cross-sectional analysis in the Netherlands Epidemiology of Obesity study, a population-based cohort including 6671 participants aged 45-65. We excluded part... Abstract
Cited 15 times since 2017 (1.8 per year) source: EuropePMC
Clinical and experimental dermatology, Volume 42, Issue 5, 22 4 2017, Pages 536-538 Guttate psoriasis triggered by perianal streptococcal infection. Garritsen FM, Kraag DE, de Graaf M
The association of guttate psoriasis (GP) with streptococcal pharyngitis is well accepted. However, less is known about the association with perianal streptococcal infection. We report a case of a 19-month-old boy with GP after a preceding perianal streptococcal dermatitis, with no clinical signs of a streptococcal pharyngitis. Treatment with phenethicillin was given together with mometasone ointment. After 4 weeks, the perianal redness was reduced and the psoriasis had improved significantly. A... Abstract
Cited 4 times since 2017 (0.5 per year) source: EuropePMC
Child development, Volume 89, Issue 3, 19 3 2017, Pages 897-913 Using a Group-Centered Approach to Observe Interactions in Early Childhood Education. van Schaik SDM, Leseman PPM, de Haan M
This study examined the value of using a group-centered approach to evaluate process quality of early childhood education and care (ECEC). Is observed support of group processes a different aspect of classroom quality, and does it predict children's collaborative play in ECEC in the Netherlands? In two play situations, 37 teachers and 120 two- to four-year-old children were observed with the Classroom Assessment Scoring System (CLASS) Toddler and two new measures. In a two-level structural... Abstract