8892 results
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
Volume 25, Issue 6, 24 4 2017, Pages 644-645
Identification of Childhood Abuse in Patients with Late-Life Depression May Help to Optimize Treatment.
Schramm E, van Schaik A
Abstract
Cited 27 times since 2017 (3.1 per year)
source: EuropePMC
RNA biology,
Volume 14, Issue 9, 23 4 2017, Pages 1089-1098
Antibodies specific for nucleic acid modifications.
Feederle R, Schepers A
Nucleotide modifications constitute marks in RNA and DNA that contribute to gene regulation, development and other cellular processes. The understanding of their intricate molecular roles has been hampered by the high number of different modifications, the lack of effective methods and tools for their detection and quantification as well as by their complex structure-function relationship. The recent development of RNA and DNA immunoprecipitation followed by high-throughput sequencing (RIP- and...
Abstract
Cited 13 times since 2017 (1.5 per year)
source: EuropePMC
Annals of intensive care,
Volume 7, Issue 1, 23 4 2017, Pages 20
Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting.
Helmerhorst HJF, de Wilde RBP, Lee DH, Palmen M, Jansen JRC, van Westerloo DJ, de Jonge E
Background: Although oxygen is generally administered in a liberal manner in the perioperative setting, the effects of oxygen administration on dynamic cardiovascular parameters, filling status and cerebral perfusion have not been fully unraveled. Our aim was to study the acute hemodynamic and microcirculatory changes before, during and after arterial hyperoxia in mechanically ventilated patients after coronary artery bypass grafting (CABG) surgery. Methods: This was a single-center physiologica...
Abstract
Cited 45 times since 2017 (5.2 per year)
source: EuropePMC
Circulation. Cardiovascular quality and outcomes,
Volume 10, Issue 2, 22 4 2017, Pages e003178
Does the Use of a Decision Aid Improve Decision Making in Prosthetic Heart Valve Selection? A Multicenter Randomized Trial.
Korteland NM, Ahmed Y, Koolbergen DR, Brouwer M, de Heer F, Kluin J, Bruggemans EF, Klautz RJ, Stiggelbout AM, Bucx JJ, Roos-Hesselink JW, Polak P, Markou T, van den Broek I, Ligthart R, Bogers AJ, Takkenberg JJ
Background: A Dutch online patient decision aid to support prosthetic heart valve selection was recently developed. A multicenter randomized controlled trial was conducted to assess whether use of the patient decision aid results in optimization of shared decision making in prosthetic heart valve selection. Methods and results: In a 5-center randomized controlled trial, patients were allocated to receive either standard preoperative care (control group) or additional access to the patient decisi...
Abstract
Cardiovascular revascularization medicine : including molecular interventions,
Volume 18, Issue 6 Suppl 1, 20 3 2017, Pages 48-51
Microcatheters: A valuable tool in the presence of a challenging coronary anatomy in the setting of acute coronary interventions. Case report and mini review.
Karalis I, Andreou C, Montero Cabezas JM, Schalij MJ
Popularity of microcatheters (MCs) is growing among interventional cardiologists, especially when complex coronary anatomy is involved. However, MCs are still considered by many as a niche tool and their value in common clinical practice and in the setting of acute coronary interventions has not been fully appreciated. This case report highlights the decisive role of MC use in the successful completion of a primary percutaneous coronary intervention. Characteristics and indications of the most c...
Abstract
Cited 16 times since 2017 (1.8 per year)
source: EuropePMC
Archives of cardiovascular diseases,
Volume 110, Issue 5, 17 3 2017, Pages 354-362
Ventricular arrhythmias and sudden death in tetralogy of Fallot.
Maury P, Sacher F, Rollin A, Mondoly P, Duparc A, Zeppenfeld K, Hascoet S, Réseau francophone de rythmologie pédiatrique et congénitale
Malignant ventricular arrhythmias and sudden cardiac death may late happen in repaired tetralogy of Fallot, although probably less frequently than previously thought, especially with the advent of new surgical techniques/management. Ventricular tachycardias are caused by reentry around the surgical scars/patches and valves. Many predictive factors have been proposed, which suffer from poor accuracy. There is currently no recommended indication for prophylactic implantable cardioverter defibrilla...
Abstract
Cited 3 times since 2017 (0.3 per year)
source: EuropePMC
PloS one,
Volume 12, Issue 2, 16 3 2017, Pages e0172595
Correction: A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics.
Mizzi C, Dalabira E, Kumuthini J, Dzimiri N, Balogh I, Başak N, Böhm R, Borg J, Borgiani P, Bozina N, Bruckmueller H, Burzynska B, Carracedo A, Cascorbi I, Deltas C, Dolzan V, Fenech A, Grech G, Kasiulevicius V, Kádaši Ľ, Kučinskas V, Khusnutdinova E, Loukas YL, Macek M, Makukh H, Mathijssen R, Mitropoulos K, Mitropoulou C, Novelli G, Papantoni I, Pavlovic S, Saglio G, Sertić J, Stojiljkovic M, Stubbs AP, Squassina A, Torres M, Turnovec M, van Schaik RH, Voskarides K, Wakil SM, Werk A, Del Zompo M, Zukic B, Katsila T, Lee MT, Motsinger-Rief A, Mc Leod HL, van der Spek PJ, Patrinos GP
[This corrects the article DOI: 10.1371/journal.pone.0162866.].
Abstract
Cited 11 times since 2017 (1.3 per year)
source: EuropePMC
Journal of visualized experiments : JoVE,
Issue 120, 15 3 2017
Prolonged Incubation of Acute Neuronal Tissue for Electrophysiology and Calcium-imaging.
Cameron MA, Kekesi O, Morley JW, Bellot-Saez A, Kueh S, Breen P, van Schaik A, Tapson J, Buskila Y
Acute neuronal tissue preparations, brain slices and retinal wholemount, can usually only be maintained for 6 - 8 h following dissection. This limits the experimental time, and increases the number of animals that are utilized per study. This limitation specifically impacts protocols such as calcium imaging that require prolonged pre-incubation with bath-applied dyes. Exponential bacterial growth within 3 - 4 h after slicing is tightly correlated with a decrease in tissue health. This study desc...
Abstract
Cited 13 times since 2017 (1.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 119, Issue 9, 9 2 2017, Pages 1456-1462
Relation of Myocardial Contrast-Enhanced T<sub>1</sub> Mapping by Cardiac Magnetic Resonance to Left Ventricular Reverse Remodeling After Cardiac Resynchronization Therapy in Patients With Nonischemic Cardiomyopathy.
Höke U, Khidir MJ, van der Geest RJ, Schalij MJ, Bax JJ, Delgado V, Ajmone Marsan N
Myocardial scar is known to be associated with limited left ventricular (LV) reverse remodeling after cardiac resynchronization therapy (CRT). However, the impact of diffuse myocardial interstitial fibrosis, as assessed with myocardial T1 mapping cardiac magnetic resonance (CMR), has not been studied in patients with CRT. Therefore, we aimed at evaluating the association between diffuse myocardial interstitial fibrosis, in nonischemic cardiomyopathy patients, and LV reverse remodeling after CRT....
Abstract
Cited 17 times since 2017 (2 per year)
source: EuropePMC
European journal of heart failure,
Volume 19, Issue 9, 8 2 2017, Pages 1145-1151
Impact of QRS complex duration and morphology on left ventricular reverse remodelling and left ventricular function improvement after cardiac resynchronization therapy.
van der Bijl P, Khidir M, Leung M, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Aims: To evaluate the impact of the interaction of QRS duration and morphology on left ventricular (LV) reverse remodelling and LV functional improvement in heart failure (HF) patients treated with cardiac resynchronization therapy (CRT). Methods and results: From an ongoing registry of HF patients treated with CRT according to contemporary guidelines, demographic, clinical, electrocardiographic (ECG) and echocardiographic characteristics were analysed. Patients were divided according to QRS dur...
Abstract
Cited 2 times since 2017 (0.2 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 41, 3 1 2017, Pages 259-264
Arterial Blood Pressure Induces Transient C4b-Binding Protein in Human Saphenous Vein Grafts.
Kupreishvili K, Meischl C, Vonk ABA, Stooker W, Eijsman L, Blom AM, Quax PHA, van Hinsbergh VWM, Niessen HWM, Krijnen PAJ
Background: Complement is an important mediator in arterial blood pressure-induced vein graft failure. Previously, we noted activation of cell protective mechanisms in human saphenous veins too. Here we have analyzed whether C4b-binding protein (C4bp), an endogenous complement inhibitor, is present in the vein wall. Methods: Human saphenous vein segments obtained from patients undergoing coronary artery bypass grafting (n = 55) were perfused in vitro at arterial blood pressure with either autolo...
Abstract
Cited 34 times since 2017 (3.9 per year)
source: EuropePMC
Frontiers in cellular and infection microbiology,
Volume 7, 3 1 2017, Pages 25
The SCID Mouse Model for Identifying Virulence Determinants in <i>Coxiella burnetii</i>.
van Schaik EJ, Case ED, Martinez E, Bonazzi M, Samuel JE
Coxiella burnetii is an intracellular, zoonotic pathogen that is the causative agent of Q fever. Infection most frequently occurs after inhalation of contaminated aerosols, which can lead to acute, self-limiting febrile illness or more serve chronic infections such as hepatitis or endocarditis. Macrophages are the principal target cells during infection where C. burnetii resides and replicates within a unique phagolysosome-like compartment, the Coxiella-containing vacuole (CCV). The first virule...
Abstract
Cited 30 times since 2017 (3.4 per year)
source: EuropePMC
BMC endocrine disorders,
Volume 17, Issue 1, 3 1 2017, Pages 6
Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST).
Stott DJ, Gussekloo J, Kearney PM, Rodondi N, Westendorp RG, Mooijaart S, Kean S, Quinn TJ, Sattar N, Hendry K, Du Puy R, Den Elzen WP, Poortvliet RK, Smit JW, Jukema JW, Dekkers OM, Blum M, Collet TH, McCarthy V, Hurley C, Byrne S, Browne J, Watt T, Bauer D, Ford I
Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4). Evidence is lacking about the effect of thyroid hormone treatment. We describe the protocol of a large randomised controlled trial (RCT) of Levothyroxine treatment for SCH. Methods: Participants are community-dwelling subjects aged ≥65 years with SCH, diagnosed by elevated TSH levels (≥4.6 and ≤19.9 mU/L) o...
Abstract
Cited 70 times since 2017 (8 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 101, Issue 6, 3 1 2017, Pages 763-772
Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis.
Dujic T, Zhou K, Yee SW, van Leeuwen N, de Keyser CE, Javorský M, Goswami S, Zaharenko L, Hougaard Christensen MM, Out M, Tavendale R, Kubo M, Hedderson MM, van der Heijden AA, Klimčáková L, Pirags V, Kooy A, Brøsen K, Klovins J, Semiz S, Tkáč I, Stricker BH, Palmer C, 't Hart LM, Giacomini KM, Pearson ER
Therapeutic response to metformin, a first-line drug for type 2 diabetes (T2D), is highly variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies have mainly focused on the impact of variants in metformin transporter genes, with inconsistent results. To clarify the significance of these variants in glycemic response to metformin in T2D, we performed a large-scale meta-analysis across the cohorts of the Metformin Genetics Consortium (MetGen). Nine candidate pol...
Abstract
Cited 46 times since 2017 (5.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 69, Issue 5, 1 1 2017, Pages 497-507
Isolated Subepicardial Right Ventricular Outflow Tract Scar in Athletes With Ventricular Tachycardia.
Venlet J, Piers SR, Jongbloed JD, Androulakis AF, Naruse Y, den Uijl DW, Kapel GF, de Riva M, van Tintelen JP, Barge-Schaapveld DQ, Schalij MJ, Zeppenfeld K
Background: High-level endurance training has been associated with right ventricular pathological remodeling and ventricular tachycardia (VT). Although overlap with arrhythmogenic right ventricular cardiomyopathy (ARVC) has been suggested, the arrhythmogenic substrate for VTs in athletes is unknown. Objectives: The goal of this study was to evaluate whether electroanatomic scar patterns related to sustained VT can distinguish exercise-induced arrhythmogenic remodeling from ARVC and post-inflamma...
Abstract
Cited 18 times since 2017 (2.1 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 10, Issue 4, 1 1 2017, Pages 388-390
Bioprosthetic Heart Valves, Thrombosis, Anticoagulation, and Imaging Surveillance.
Bax JJ, Delgado V
Abstract
Cited 34 times since 2017 (3.9 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 10, Issue 2, 1 1 2017, Pages e004614
Association Between Posterior Left Atrial Adipose Tissue Mass and Atrial Fibrillation.
van Rosendael AR, Dimitriu-Leen AC, van Rosendael PJ, Leung M, Smit JM, Saraste A, Knuuti J, van der Geest RJ, van der Arend BW, van Zwet EW, Scholte AJ, Delgado V, Bax JJ
Background: Epicardial adipose tissue located close to the atrial wall can change the electric conduction of the left atrium, potentially leading to atrial fibrillation (AF). The aim of this study was to assess whether an increased atrial adipose tissue mass posterior to the left atrium is related to AF independent of demographical and cardiovascular risk factors. Methods and results: Two hundred patients with AF and 200 patients without AF who underwent computed tomographic angiography were inc...
Abstract
Cited 3 times since 2017 (0.3 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 6, 1 1 2017, Pages 390-399
The year in cardiology 2016: imaging.
Delgado V, Gaemperli O, Lombardi M, Kaufmann PA, Bax JJ
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 24, Issue 1, 1 1 2017, Pages 180-187
Multimodality imaging: Bird's eye view from The European Society of Cardiology Congress 2016 : Rome, August 27-31, 2016.
Bax JJ, Delgado V, Achenbach S, Plein S, Kaufmann PA
Abstract
Cited 2 times since 2017 (0.2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 2, 1 1 2017, Pages 63-64
Guidance of interventions in structural heart disease; three-dimensional techniques are here to stay.
Voskuil M, Sievert H, Arslan F
Abstract
