8892 results
Cited 14 times since 2017 (1.6 per year)
source: EuropePMC
Atherosclerosis,
Volume 257, 16 3 2017, Pages 186-194
Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.
Simic B, Mocharla P, Crucet M, Osto E, Kratzer A, Stivala S, Kühnast S, Speer T, Doycheva P, Princen HM, van der Hoorn JW, Jukema JW, Giral H, Tailleux A, Landmesser U, Staels B, Lüscher TF
Background and aims: High-density lipoprotein cholesterol (HDL-C) is inversely related to cardiovascular risk. HDL-C raising ester transfer protein (CETP) inhibitors, are novel therapeutics. We studied the effects of CETP inhibitors anacetrapib and evacetrapib on triglycerides, cholesterol and lipoproteins, cholesterol efflux, paraoxonase activity (PON-1), reactive oxygen species (ROS), and endothelial function in E3L and E3L.CETP mice. Methods: Triglycerides and cholesterol were measured at wee...
Abstract
Cited 100 times since 2017 (11.4 per year)
source: EuropePMC
The Cochrane database of systematic reviews,
Volume 1, 13 2 2017, Pages CD010369
Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews.
Oaklander AL, Lunn MP, Hughes RA, van Schaik IN, Frost C, Chalk CH
Background: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic progressive or relapsing and remitting disease that usually causes weakness and sensory loss. The symptoms are due to autoimmune inflammation of peripheral nerves. CIPD affects about 2 to 3 per 100,000 of the population. More than half of affected people cannot walk unaided when symptoms are at their worst. CIDP usually responds to treatments that reduce inflammation, but there is disagreement about which t...
Abstract
Cited 14 times since 2017 (1.6 per year)
source: EuropePMC
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association,
Volume 26, Issue 5, 12 2 2017, Pages 1114-1120
Cardiorespiratory Fitness after Transient Ischemic Attack and Minor Ischemic Stroke: Baseline Data of the MoveIT Study.
Boss HM, Deijle IA, Van Schaik SM, de Melker EC, van den Berg BTJ, Weinstein HC, Geerlings MI, Kappelle LJ, Van den Berg-Vos RM
Background: Cardiorespiratory fitness (CRF) is reduced in patients with stroke. It is unclear whether it is also reduced in patients with a transient ischemic attack (TIA) or minor stroke. We investigated the CRF in patients with a recent TIA or minor stroke and explored which determinants are associated with a lower fitness. Methods: In 113 patients with a recent TIA or minor ischemic stroke (64 (SD = 10) years of age; 49 (IQR 27-86) days post TIA or stroke), the peak oxygen consumption (VO2pea...
Abstract
Cited 31 times since 2017 (3.5 per year)
source: EuropePMC
Scientific reports,
Volume 7, 9 2 2017, Pages 40052
Orientation toward humans predicts cognitive performance in orang-utans.
Damerius LA, Forss SI, Kosonen ZK, Willems EP, Burkart JM, Call J, Galdikas BM, Liebal K, Haun DB, van Schaik CP
Non-human animals sometimes show marked intraspecific variation in their cognitive abilities that may reflect variation in external inputs and experience during the developmental period. We examined variation in exploration and cognitive performance on a problem-solving task in a large sample of captive orang-utans (Pongo abelii &P. pygmaeus, N = 103) that had experienced different rearing and housing conditions during ontogeny, including human exposure. In addition to measuring exploration...
Abstract
Cited 5 times since 2017 (0.6 per year)
source: EuropePMC
The Spanish journal of psychology,
Volume 19, 9 2 2017, Pages E99
The Ecology of Social Learning in Animals and its Link with Intelligence.
van Schaik C, Graber S, Schuppli C, Burkart J
Classical ethology and behavioral ecology did not pay much attention to learning. However, studies of social learning in nature reviewed here reveal the near-ubiquity of reliance on social information for skill acquisition by developing birds and mammals. This conclusion strengthens the plausibility of the cultural intelligence hypothesis for the evolution of intelligence, which assumes that selection on social learning abilities automatically improves individual learning ability. Thus, intellig...
Abstract
Cited 3 times since 2017 (0.3 per year)
source: EuropePMC
American heart journal,
Volume 186, 2 1 2017, Pages 83-90
Right vEntricular Dysfunction in tEtralogy of Fallot: INhibition of the rEnin-angiotensin-aldosterone system (REDEFINE) trial: Rationale and design of a randomized, double-blind, placebo-controlled clinical trial.
Bokma JP, Winter MM, Kornaat EM, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Post MC, Berbee JK, Zwinderman AH, Mulder BJM, Bouma BJ
Renin-angiotensin-aldosterone system (RAAS) inhibition with angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors is beneficial in patients with acquired left ventricular dysfunction. Adult patients with tetralogy of Fallot (TOF) with right ventricular (RV) dysfunction are at high risk for heart failure, arrhythmias, and sudden cardiac death. However, the efficacy of RAAS inhibition has not been established in these patients. Methods: The REDEFINE is an investigator-initia...
Abstract
Cited 34 times since 2017 (3.9 per year)
source: EuropePMC
Current opinion in virology,
Volume 22, 2 1 2017, Pages 64-70
Capturing norovirus transmission.
de Graaf M, Villabruna N, Koopmans MP
Human norovirus is a leading cause of gastroenteritis and is efficiently transmitted between humans and around the globe. The burden of norovirus infections in the global community and in health-care settings warrant the availability of outbreak prevention strategies and control measures that are tailored to the pathogen, outbreak setting and population at risk. A better understanding of viral and host determinants of transmission would aid in developing and fine-tuning such efforts. Here, we de...
Abstract
Cited 20 times since 2017 (2.3 per year)
source: EuropePMC
Journal of Alzheimer's disease : JAD,
Volume 58, Issue 1, 1 1 2017, Pages 275-283
Left Ventricular Hypertrophy and Cognitive Decline in Old Age.
Mahinrad S, Vriend AE, Jukema JW, van Heemst D, Sattar N, Blauw GJ, Macfarlane PW, Clark EN, de Craen AJM, Sabayan B
Background: Patients with advanced heart failure run a greater risk of dementia. Whether early cardiac structural changes also associate with cognitive decline is yet to be determined. Objective: We tested whether left ventricular hypertrophy (LVH) derived from electrocardiogram associates with cognitive decline in older subjects at risk of cardiovascular disease. Methods: We included 4,233 participants (mean age 75.2 years, 47.8% male) from PROSPER (PROspective Study of Pravastatin in the Elder...
Abstract
Cited 87 times since 2017 (9.9 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 4, 1 1 2017, Pages 268-276
Arrhythmogenic anatomical isthmuses identified by electroanatomical mapping are the substrate for ventricular tachycardia in repaired Tetralogy of Fallot.
Kapel GF, Sacher F, Dekkers OM, Watanabe M, Blom NA, Thambo JB, Derval N, Schalij MJ, Jalal Z, Wijnmaalen AP, Zeppenfeld K
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 161, 1 1 2017, Pages D1570
[Pulmonary embolism response teams: what is the added value for patients with acute pulmonary embolism?]
Huisman MV, Montero Cabezas JM, Klok FA
Adequate triaging of patients presenting with acute pulmonary embolism (PE) is essential for appropriate treatment, especially for patients with severe PE. Optimal treatment for this latter group of patients includes pharmaco-mechanical reperfusion treatment for the minority of patients who present with haemodynamic instability, and standard anticoagulation and close monitoring on the ward for the intermediate-high risk patient. In the USA, pulmonary embolism response teams (PERT) have been intr...
Abstract
Cited 16 times since 2017 (1.8 per year)
source: EuropePMC
Emerging infectious diseases,
Volume 23, Issue 1, 1 1 2017, Pages 87-91
Norovirus Infection in Harbor Porpoises.
de Graaf M, Bodewes R, van Elk CE, van de Bildt M, Getu S, Aron GI, Verjans GM, Osterhaus AD, van den Brand JM, Kuiken T, Koopmans MP
A norovirus was detected in harbor porpoises, a previously unknown host for norovirus. This norovirus had low similarity to any known norovirus. Viral RNA was detected primarily in intestinal tissue, and specific serum antibodies were detected in 8 (24%) of 34 harbor porpoises from the North Sea.
Abstract
Nederlands tijdschrift voor geneeskunde,
Volume 161, 1 1 2017, Pages D927
[Assessments during Medical Specialists Training: quantity or quality?]
Hamming JF
Structured assessments form a mandatory part of Dutch Medical Specialist Training, but create administrative workload for both the staff and supervisors. One could argue that the quality of the narrative feedback is more important than the extensive reporting in learning portfolios, and that the focus should be on continuous on-the-job coaching.
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 161, 1 1 2017, Pages D1090
[How we can learn better and more safely from serious incidents; translation of 'Just Culture' and 'Safety-II' into clinical practice].
de Vos MS, den Dijker L, Hamming JF
After a serious incident, all involved expect it will provide an opportunity to learn and that improvements will follow. However, 'safe' learning is often threatened due to a primary focus on accountability. Focus should, instead, be on the needs of both patients and care providers, with the goal of repairing damage and restoring trust in the wider sense - a culture of justice ('Just Culture'). Common daily practice is a more realistic focus for further investigation, with ac...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 161, 1 1 2017, Pages D999
[How does a surgeon decide that surgery is the best option?Assessing whether or not to operate].
Hamming JF, Marang-van de Mheen PJ
All abdominal surgical procedures have a certain risk/benefit ratio. Recently, the way surgeons come to a decision whether to operate, or not, was discussed in the Annals of Surgery. First, the assessment of the decision for an operative versus a non-operative strategy was addressed on the basis of clinical vignettes. The perceptions concerning risk/benefit balance varied considerably between surgeons and these perceptions predicted the decision to operate. In a second paper, surgeons were rando...
Abstract
Cited 11 times since 2017 (1.3 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 12, Issue 13, 1 1 2017, Pages 1660-1666
Left bundle branch block after sutureless, transcatheter, and stented biological aortic valve replacement for aortic stenosis.
Regeer MV, Merkestein LR, de Weger A, Kamperidis V, van der Kley F, van Rosendael PJ, Marsan NA, Klautz RJ, Schalij MJ, Bax JJ, Delgado V
Aims: Conventional aortic valve replacement (AVR), sutureless AVR (su-AVR) and transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) are associated with conduction abnormalities. The aim of the present study was to assess the incidence of left bundle branch block (LBBB) after su-AVR and TAVI, in comparison to conventional AVR. Methods and results: A total of 501 patients (mean age 74±8 years, 53% male) without preoperative cardiac conduction disturbances who underwent AV...
Abstract
Cited 9 times since 2017 (1 per year)
source: EuropePMC
The Turkish journal of pediatrics,
Volume 59, Issue 6, 1 1 2017, Pages 642-647
Cerebral oxygen saturation monitoring in pediatric cardiopulmonary resuscitation patients in the emergency settings: A small descriptive study.
Çağlar A, Er A, Ulusoy E, Akgül F, Çitlenbik H, Yılmaz D, Duman M
Çağlar A, Er A, Ulusoy E, Akgül F, Çitlenbik H, Yılmaz D, Duman M. Cerebral oxygen saturation monitoring in pediatric cardiopulmonary resuscitation patients in the emergency settings: A small descriptive study. Turk J Pediatr 2017; 59: 642-647. Near infrared spectroscopy (NIRS) is a new technology for monitoring cardiopulmonary resuscitation (CPR). The use of NIRS has advantages in monitoring cerebral oxygenation in cardiac arrest patients. The aim of this study was to describe cerebral regional...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
The Turkish journal of pediatrics,
Volume 59, Issue 3, 1 1 2017, Pages 281-287
Are cytokines and cortisol important predictors for the severity of pediatric croup: A case control study.
Üzüm Ö, Çağlar A, Küme T, Sayıner A, Er A, Akgül F, Ulusoy E, Yılmaz D, Duman M
Üzüm Ö, Çağlar A, Küme T, Sayıner A, Er A, Akgül F, Ulusoy E, Yılmaz D, Duman M. Are cytokines and cortisol important predictors for the severity of pediatric croup: A case control study. Turk J Pediatr 2017; 59: 281-287. The aim of this study is to investigate the role of cytokines (TNF-α, IL-6, IL-10, and PAF), cortisol, and IgE in the pathogenesis of croup and the factors determining its clinical severity. Patients diagnosed with croup at the Pediatric Emergency Department were included and t...
Abstract
Cited 16 times since 2017 (1.8 per year)
source: EuropePMC
Current health sciences journal,
Volume 43, Issue 1, 1 1 2017, Pages 20-24
Research on Sleep Quality and the Factors Affecting the Sleep Quality of the Nursing Students.
Yilmaz D, Tanrikulu F, Dikmen Y
Purpose: This research has been conducted in order to examine the quality of sleep and the factors affecting the sleep quality. Material/methods: The sample of this descriptive research is comprised of 223 volunteer students studying at Uludağ University Faculty of Health Sciences Department of Nursing. Research datas have been collected through personal features survey and Pittsburg Sleep Quality Index(PSQI). Results: The average result derived from the sample is 6.52±3.17. To briefly explain t...
Abstract
Cited 9 times since 2017 (1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 19, Issue 1, 1 1 2017, Pages 72-80
Application and comparison of the FADES, MADIT, and SHFM-D risk models for risk stratification of prophylactic implantable cardioverter-defibrillator treatment.
van der Heijden AC, van Rees JB, Levy WC, van der Bom JG, Cannegieter SC, de Bie MK, van Erven L, Schalij MJ, Borleffs CJ
Aims: Implantable cardioverter-defibrillator (ICD) treatment is beneficial in selected patients. However, it remains difficult to accurately predict which patients benefit most from ICD implantation. For this purpose, different risk models have been developed. The aim was to validate and compare the FADES, MADIT, and SHFM-D models. Methods and results: All patients receiving a prophylactic ICD at the Leiden University Medical Center were evaluated. Individual model performance was evaluated by C...
Abstract
Cited 2 times since 2017 (0.2 per year)
source: EuropePMC
The Behavioral and brain sciences,
Volume 40, 1 1 2017, Pages e224
Future directions for studying the evolution of general intelligence.
Burkart JM, Schubiger MN, van Schaik CP
The goal of our target article was to lay out current evidence relevant to the question of whether general intelligence can be found in nonhuman animals in order to better understand its evolution in humans. The topic is a controversial one, as evident from the broad range of partly incompatible comments it has elicited. The main goal of our response is to translate these issues into testable empirical predictions, which together can provide the basis for a broad research agenda.
Abstract
