8892 results
Cited 13 times since 2016 (1.5 per year)
source: EuropePMC
Parasitology research,
Volume 116, Issue 2, 18 3 2016, Pages 589-599
Host social organization and mating system shape parasite transmission opportunities in three European bat species.
van Schaik J, Kerth G
For non-mobile parasites living on social hosts, infection dynamics are strongly influenced by host life history and social system. We explore the impact of host social systems on parasite population dynamics by comparing the infection intensity and transmission opportunities of three mite species of the genus Spinturnix across their three European bat hosts (Myotis daubentonii, Myotis myotis, Myotis nattereri) during the bats' autumn mating season. Mites mainly reproduce in host maternity...
Abstract
Cited 32 times since 2016 (3.6 per year)
source: EuropePMC
Journal of dairy science,
Volume 100, Issue 1, 17 3 2016, Pages 562-571
Prevalence and risk factors for extended-spectrum β-lactamase or AmpC-producing Escherichia coli in organic dairy herds in the Netherlands.
Santman-Berends IMGA, Gonggrijp MA, Hage JJ, Heuvelink AE, Velthuis A, Lam TJGM, van Schaik G
Extended-spectrum β-lactamase and AmpC-producing Escherichia coli (ESBL/AmpC) are an emerging problem and are hypothesized to be associated with antimicrobial use (AMU), and more specifically with the use of third- and fourth-generation cephalosporins. Whether ESBL/AmpC also occur in organic dairy herds, which have restricted AMU, is not known. Additionally, it is unknown whether, in addition to restricted AMU, other factors in organic herd management are associated with ESBL/AmpC herd status. T...
Abstract
Cited 56 times since 2016 (6.3 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 30, Issue 1, 11 2 2016, Pages 71-79.e1
Left Atrial Dysfunction in the Pathogenesis of Cryptogenic Stroke: Novel Insights from Speckle-Tracking Echocardiography.
Leong DP, Joyce E, Debonnaire P, Katsanos S, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Background: Myocardial strain analysis by speckle-tracking echocardiography, which can detect subtle abnormalities in left atrial (LA) function, may offer unique insights into LA pathophysiology in patients with cryptogenic stroke (CS). The aim of this study was to investigate whether LA reservoir strain by speckle-tracking echocardiography, as a measure of LA compliance, is impaired in patients with CS and no history of atrial fibrillation. Methods: A retrospective case-control study of 742 pat...
Abstract
Cited 6 times since 2016 (0.7 per year)
source: EuropePMC
European journal of heart failure,
Volume 19, Issue 1, 11 2 2016, Pages 80-87
Effect of cardiac resynchronization therapy in patients with diabetes randomized in EchoCRT.
Nägele MP, Steffel J, Robertson M, Singh JP, Flammer AJ, Bax JJ, Borer JS, Dickstein K, Ford I, Gorcsan J, Gras D, Krum H, Sogaard P, Holzmeister J, Abraham WT, Brugada J, Ruschitzka F
Aims: As patients with heart failure (HF) and concomitant diabetes carry a poor prognosis, this post-hoc subgroup analysis aimed to compare the outcomes of patients with and without diabetes randomized in the Echocardiography Guided Cardiac Resynchronization Therapy (EchoCRT) study. Methods and results: EchoCRT randomized patients with a QRS duration
Abstract
Cited 5 times since 2016 (0.6 per year)
source: EuropePMC
PloS one,
Volume 11, Issue 11, 11 2 2016, Pages e0166161
Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans.
Neis EP, Bloemen JG, Rensen SS, van der Vorst JR, van den Broek MA, Venema K, Buurman WA, Dejong CH
Aim: To determine whether acute loss of liver tissue affects hepatic short-chain fatty acid (SCFA) clearance. Methods: Blood was sampled from the radial artery, portal vein, and hepatic vein before and after hepatic resection in 30 patients undergoing partial liver resection. Plasma SCFA levels were measured by liquid chromatography-mass spectrometry. SCFA exchange across gut and liver was calculated from arteriovenous differences and plasma flow. Liver volume was estimated by CT liver volumetry...
Abstract
Cited 11 times since 2016 (1.2 per year)
source: EuropePMC
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry,
Volume 22, Issue 1, 10 2 2016, Pages 61-85
Synthesis and crystal structures of novel copper(II) complexes with glycine and substituted phenanthrolines: reactivity towards DNA/BSA and in vitro cytotoxic and antimicrobial evaluation.
İnci D, Aydın R, Vatan Ö, Sevgi T, Yılmaz D, Zorlu Y, Yerli Y, Çoşut B, Demirkan E, Çinkılıç N
New copper(II) complexes-dimeric-[Cu(nphen)(gly)(H2O)]+ (1) and [Cu(dmphen)(gly)(NO3)(H2O)] (2) (nphen = 5-nitro-1,10-phenanthroline, dmphen = 4,7-dimethyl-1,10-phenanthroline, and gly = glycine)-have been synthesized and characterized by CHN analysis, single-crystal X-ray diffraction techniques, FTIR, EPR spectroscopy, and cyclic voltammetry. The CT-DNA-binding properties of these complexes have been investigated by thermal denaturation measurements and both absorption and emission spectroscopy...
Abstract
Cited 35 times since 2016 (3.9 per year)
source: EuropePMC
BMC medicine,
Volume 14, Issue 1, 10 2 2016, Pages 181
Renal function estimation and Cockroft-Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart 'OMics' in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives.
Ferreira JP, Girerd N, Pellicori P, Duarte K, Girerd S, Pfeffer MA, McMurray JJ, Pitt B, Dickstein K, Jacobs L, Staessen JA, Butler J, Latini R, Masson S, Mebazaa A, Rocca HP, Delles C, Heymans S, Sattar N, Jukema JW, Cleland JG, Zannad F, Rossignol P, Heart ‘OMics’ in AGEing (HOMAGE) initiative and the High-Risk Myocardial Infarction database initiative
Background: Renal impairment is a major risk factor for mortality in various populations. Three formulas are frequently used to assess both glomerular filtration rate (eGFR) or creatinine clearance (CrCl) and mortality prediction: body surface area adjusted-Cockcroft-Gault (CG-BSA), Modification of Diet in Renal Disease Study (MDRD4), and the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. The CKD-EPI is the most accurate eGFR estimator as compared to a "gold-standard&...
Abstract
Cited 41 times since 2016 (4.6 per year)
source: EuropePMC
PloS one,
Volume 11, Issue 11, 10 2 2016, Pages e0166041
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments.
Kohajda Z, Farkas-Morvay N, Jost N, Nagy N, Geramipour A, Horváth A, Varga RS, Hornyik T, Corici C, Acsai K, Horváth B, Prorok J, Ördög B, Déri S, Tóth D, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Baczkó I, Leprán I, Nánási PP, Papp JG, Varró A, Virág L
Background: In this study the effects of a new, highly selective sodium-calcium exchanger (NCX) inhibitor, ORM-10962 were investigated on cardiac NCX current, Ca2+ transients, cell shortening and in experimental arrhythmias. The level of selectivity of the novel inhibitor on several major transmembrane ion currents (L-type Ca2+ current, major repolarizing K+ currents, late Na+ current, Na+/K+ pump current) was also determined. Methods: Ion currents in single dog ventricular cells (cardiac myocyt...
Abstract
Cited 11 times since 2016 (1.2 per year)
source: EuropePMC
Case reports in surgery,
Volume 2016, 9 2 2016, Pages 9306262
Xiphoidectomy: A Surgical Intervention for an Underdocumented Disorder.
Hogerzeil DP, Hartholt KA, de Vries MR
Two patients who presented with nonspecific thoracic and upper abdominal symptoms and tenderness of the xiphoid process are discussed. Both patients had undergone extensive examinations, but no source for their symptoms could be found. Plain chest radiographs revealed an anterior displacement of the xiphoid process in both patients. Physical examination confirmed this to be the primary source of discomfort. Anterior displacement of the xiphoid process may be the result of significant weight gain...
Abstract
Cited 25 times since 2016 (2.8 per year)
source: EuropePMC
Journal of clinical pharmacology,
Volume 57, Issue 4, 9 2 2016, Pages 440-451
Safety and Tolerability of Neladenoson Bialanate, a Novel Oral Partial Adenosine A1 Receptor Agonist, in Patients With Chronic Heart Failure.
Voors AA, Düngen HD, Senni M, Nodari S, Agostoni P, Ponikowski P, Bax JJ, Butler J, Kim RJ, Dorhout B, Dinh W, Gheorghiade M
We studied safety and tolerability of neladenoson bialanate, a novel oral selective partial adenosine A1 receptor agonist that maintains the cardioprotective effects of adenosine without the undesired side effects of a full agonist, in 2 pilot studies in patients with heart failure with reduced ejection fraction (HFrEF). The β-blocker interaction study was a single-blind, placebo-controlled study on the effects of a 30-mg single dose of neladenoson bialanate on atrioventricular (AV) conduction i...
Abstract
Cited 13 times since 2016 (1.5 per year)
source: EuropePMC
Scientific reports,
Volume 6, 8 2 2016, Pages 35371
Gene-gene Interaction Analyses for Atrial Fibrillation.
Lin H, Mueller-Nurasyid M, Smith AV, Arking DE, Barnard J, Bartz TM, Lunetta KL, Lohman K, Kleber ME, Lubitz SA, Geelhoed B, Trompet S, Niemeijer MN, Kacprowski T, Chasman DI, Klarin D, Sinner MF, Waldenberger M, Meitinger T, Harris TB, Launer LJ, Soliman EZ, Chen LY, Smith JD, Van Wagoner DR, Rotter JI, Psaty BM, Xie Z, Hendricks AE, Ding J, Delgado GE, Verweij N, van der Harst P, Macfarlane PW, Ford I, Hofman A, Uitterlinden A, Heeringa J, Franco OH, Kors JA, Weiss S, Völzke H, Rose LM, Natarajan P, Kathiresan S, Kääb S, Gudnason V, Alonso A, Chung MK, Heckbert SR, Benjamin EJ, Liu Y, März W, Rienstra M, Jukema JW, Stricker BH, Dörr M, Albert CM, Ellinor PT
Atrial fibrillation (AF) is a heritable disease that affects more than thirty million individuals worldwide. Extensive efforts have been devoted to the study of genetic determinants of AF. The objective of our study is to examine the effect of gene-gene interaction on AF susceptibility. We performed a large-scale association analysis of gene-gene interactions with AF in 8,173 AF cases, and 65,237 AF-free referents collected from 15 studies for discovery. We examined putative interactions between...
Abstract
Cited 17 times since 2016 (1.9 per year)
source: EuropePMC
BMC geriatrics,
Volume 16, Issue 1, 4 1 2016, Pages 179
Cost-utility of medication withdrawal in older fallers: results from the improving medication prescribing to reduce risk of FALLs (IMPROveFALL) trial.
Polinder S, Boyé ND, Mattace-Raso FU, Van der Velde N, Hartholt KA, De Vries OJ, Lips P, Van der Cammen TJ, Patka P, Van Beeck EF, Van Lieshout EM, IMPROveFALL trial collaborators
Background: The use of Fall-Risk-Increasing-Drugs (FRIDs) has been associated with increased risk of falls and associated injuries. This study investigates the effect of withdrawal of FRIDs versus 'care as usual' on health-related quality of life (HRQoL), costs, and cost-utility in community-dwelling older fallers. Methods: In a prospective multicenter randomized controlled trial FRIDs assessment combined with FRIDs-withdrawal or modification was compared with 'care as usual'...
Abstract
Cited 69 times since 2016 (7.7 per year)
source: EuropePMC
Circulation,
Volume 135, Issue 3, 3 1 2016, Pages 264-279
Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide, Troponin-T, and Growth-Differentiation Factor 15 in Adult Congenital Heart Disease.
Baggen VJ, van den Bosch AE, Eindhoven JA, Schut AW, Cuypers JA, Witsenburg M, de Waart M, van Schaik RH, Zijlstra F, Boersma E, Roos-Hesselink JW
Background: The number of patients with adult congenital heart disease (ACHD) is rapidly increasing. To optimize patient management, there is a great need to accurately identify high-risk patients. Still, no biomarker has been firmly established as a clinically useful prognostic tool in this group. We studied the association of N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitive troponin-T, and growth-differentiation factor 15 with cardiovascular events in ACHD. Methods: Clinic...
Abstract
Cited 43 times since 2016 (4.8 per year)
source: EuropePMC
Proceedings. Biological sciences,
Volume 283, Issue 1843, 1 1 2016, Pages 20161817
Female monkeys use both the carrot and the stick to promote male participation in intergroup fights.
Arseneau-Robar TJ, Taucher AL, Müller E, van Schaik C, Bshary R, Willems EP
Group-level cooperation often poses a social dilemma in which joint action may be difficult to achieve. Theoretical models and experimental work on humans show that social incentives, such as punishment of defectors and rewarding of cooperators, can promote cooperation in groups of unrelated individuals. Here, we demonstrate that these processes can operate in a non-human animal species, and be used to effectively promote the production of a public good. We took advantage of the fact that interg...
Abstract
Cited 11 times since 2016 (1.2 per year)
source: EuropePMC
Physiology (Bethesda, Md.),
Volume 31, Issue 6, 1 1 2016, Pages 392-397
Evolutionary Medicine: The Ongoing Evolution of Human Physiology and Metabolism.
Rühli F, van Schaik K, Henneberg M
The field of evolutionary medicine uses evolutionary principles to understand changes in human anatomy and physiology that have occurred over time in response to environmental changes. Through this evolutionary-based approach, we can understand disease as a consequence of anatomical and physiological "trade-offs" that develop to facilitate survival and reproduction. We demonstrate how diachronic study of human anatomy and physiology is fundamental for an increased understanding of huma...
Abstract
Cited 202 times since 2016 (22.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 68, Issue 21, 1 1 2016, Pages 2299-2307
Long-Term Arrhythmic and Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers.
Kumar S, Baldinger SH, Gandjbakhch E, Maury P, Sellal JM, Androulakis AF, Waintraub X, Charron P, Rollin A, Richard P, Stevenson WG, Macintyre CJ, Ho CY, Thompson T, Vohra JK, Kalman JM, Zeppenfeld K, Sacher F, Tedrow UB, Lakdawala NK
Background: Mutations in LMNA are variably expressed and may cause cardiomyopathy, atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA). Detailed natural history studies of LMNA-associated arrhythmic and nonarrhythmic outcomes are limited, and the prognostic significance of the index cardiac phenotype remains uncertain. Objectives: This study sought to describe the arrhythmic and nonarrhythmic outcomes of LMNA mutation carriers and to assess the prognostic s...
Abstract
Cited 7 times since 2016 (0.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 24, Issue 11, 1 1 2016, Pages 675-681
The effect of losartan therapy on ventricular function in Marfan patients with haploinsufficient or dominant negative FBN1 mutations.
den Hartog AW, Franken R, van den Berg MP, Zwinderman AH, Timmermans J, Scholte AJ, de Waard V, Spijkerboer AM, Pals G, Mulder BJ, Groenink M
Background: Mild biventricular dysfunction is often present in patients with Marfan syndrome. Losartan has been shown to reduce aortic dilatation in patients with Marfan syndrome. This study assesses the effect of losartan on ventricular volume and function in genetically classified subgroups of asymptomatic Marfan patients without significant valvular regurgitation. Methods: In this predefined substudy of the COMPARE study, Marfan patients were classified based on the effect of their FBN1 mutat...
Abstract
Cited 119 times since 2016 (13.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 68, Issue 19, 1 1 2016, Pages 2047-2055
Long-Term Clinical Outcomes of Subcutaneous Versus Transvenous Implantable Defibrillator Therapy.
Brouwer TF, Yilmaz D, Lindeboom R, Buiten MS, Olde Nordkamp LR, Schalij MJ, Wilde AA, van Erven L, Knops RE
Background: Transvenous implantable cardioverter-defibrillators (TV-ICDs) improve survival in patients at risk for sudden cardiac death, but complications remain an important drawback. The subcutaneous ICD (S-ICD) was developed to overcome lead-related complications. Comparison of clinical outcomes of both device types in previous studies was hampered by dissimilar patient characteristics. Objectives: This retrospective study compares long-term clinical outcomes of S-ICD and TV-ICD therapy in a...
Abstract
Cited 56 times since 2016 (6.2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 103, Issue 9, 1 1 2016, Pages 666-671
QRS fragmentation is superior to QRS duration in predicting mortality in adults with tetralogy of Fallot.
Bokma JP, Winter MM, Vehmeijer JT, Vliegen HW, van Dijk AP, van Melle JP, Meijboom FJ, Post MC, Zwinderman AH, Mulder BJ, Bouma BJ
Background: Although QRS duration >180 ms has prognostic value in adults with tetralogy of Fallot (TOF), its sensitivity to predict mortality is low. Fragmented QRS complexes, a simple measurement on ECG, are related to myocardial fibrosis and dysfunction in patients with TOF. Our objective was to determine whether QRS fragmentation predicts major outcomes in TOF. Methods: This multicentre study included adult patients with TOF from a prospective registry. Notches in the QRS complex in ≥2 con...
Abstract
Cited 14 times since 2016 (1.6 per year)
source: EuropePMC
Clinical nurse specialist CNS,
Volume 30, Issue 6, 1 1 2016, Pages E7-E12
The Effect of the Z-Track Technique on Pain and Drug Leakage in Intramuscular Injections.
Yilmaz D, Khorshid L, Dedeoğlu Y
Purpose/aims: The aim of this study was to investigate the effects of the Z-track technique in the administration of intramuscular diclofenac, a nonsteroidal anti-inflammatory drug, on pain and drug leakage. Design: This is a semiexperimental and randomized controlled study. Methods: It was felt necessary to conduct this study to compare the effects on pain and drug leakage of the standard intramuscular injection method and the "Z-track technique," which is claimed to be helpful in thi...
Abstract
