7401 results
Cureus,
Volume 16, Issue 10, 15 3 2024, Pages e71545
Should Gallbladder Pathologies Be Investigated in Patients With Colon Polyps?
Turhan N, Ertorul D, Duran C, Kılıç MG, Kuzan TY, Yaşar S, Yılmaz D, Zarbaliyev E
Background Data regarding the frequency of development of gallbladder pathologies in patients with colon polyps are quite limited and heterogeneous. Hence, this study aimed to investigate whether colon polyps cause an increased risk of developing gallbladder pathologies and the necessity of ultrasonographic screening. Methodology This retrospective, cross-sectional study was conducted among adult patients who underwent a colonoscopy and hepatobiliary ultrasound as part of their health check-up f...
Abstract
Cited 2 times since 2024 (2.1 per year)
source: EuropePMC
JACC. Advances,
Volume 3, Issue 11, 14 2 2024, Pages 101327
30 Years' Experience in Percutaneous Pulmonary Artery Interventions in Transposition of the Great Arteries.
Joosen RS, van der Palen RLF, Udink Ten Cate FEA, Voskuil M, Krings GJ, Bökenkamp R, Molenschot MC, Hahurij ND, Dickinson MG, Hazekamp MG, Schoof PH, Slieker MG, Straver B, Blom NA, Breur JMPJ
Background: Pulmonary artery (PA) stenosis is common after arterial switch operation (ASO) for transposition of the great arteries (TGA). Differences between balloon angioplasty (BA) and stents on right ventricular (RV) and PA pressures are not well studied. Objectives: The purpose of this study was to analyze percutaneous PA interventions' frequency after ASO, complications, and the effects of BA and stents on RV and PA pressures. Methods: All TGA patients with ASO between 1977 and 2022 in...
Abstract
Cited 3 times since 2024 (3.2 per year)
source: EuropePMC
European journal of clinical investigation,
Volume 54, Issue 12, 13 2 2024, Pages e14317
Cardiac troponin elevation and mortality in takotsubo syndrome: New insights from the international takotsubo registry.
Stähli BE, Schindler M, Schweiger V, Cammann VL, Szawan KA, Niederseer D, Würdinger M, Schönberger A, Schönberger M, Koleva I, Mercier JC, Petkova V, Mayer S, Citro R, Vecchione C, Bossone E, Gili S, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Jansen T, D'Ascenzo F, Dichtl W, von Lewinski D, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Massoomi M, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Kato K, Ishibashi I, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm
Background: The clinical relevance of cardiac troponin (cTn) elevation in takotsubo syndrome (TTS) remains uncertain. The present study sought to investigate the role of cardiac troponin (cTn) elevations in mortality prediction of patients with Takotsubo syndrome (TTS). Methods: Patients enrolled in the International Takotsubo (InterTAK) Registry from January 2011 to February 2020 with available data on peak cTn levels were included in the analysis. Peak cTn levels during the index hospitalizati...
Abstract
Cited 3 times since 2024 (3.2 per year)
source: EuropePMC
Advances in simulation (London, England),
Volume 9, Issue 1, 12 2 2024, Pages 43
Changing the conversation: impact of guidelines designed to optimize interprofessional facilitation of simulation-based team training.
Ju M, Bochatay N, Werne A, Essakow J, Tsang L, Nottingham M, Franzon D, Lyndon A, van Schaik S
Background: Interprofessional simulation-based team training (ISBTT) is commonly used to optimize interprofessional teamwork in healthcare. The literature documents the benefits of ISBTT, yet effective interprofessional collaboration continues to be challenged by complex hierarchies and power dynamics. Explicitly addressing these issues during ISBTT may help participants acquire skills to navigate such challenges, but guidelines on how to do this are limited. Methods: We applied an educational d...
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
EBioMedicine,
Volume 109, 12 2 2024, Pages 105391
Patterns of the within-host evolution of human norovirus in immunocompromised individuals and implications for treatment.
Izquierdo-Lara RW, Villabruna N, Hesselink DA, Schapendonk CME, Ribó Pons S, Nieuwenhuijse D, Meier JIJ, Goodfellow I, Dalm VASH, Fraaij PLA, van Kampen JJA, Koopmans MPG, de Graaf M
Background: Currently, there is no licensed treatment for chronic norovirus infections, but the use of intra-duodenally-delivered immunoglobulins is promising; nevertheless, varying results have limited their wide use. Little is known about the relationship between norovirus genetic diversity and treatment efficacy. Methods: We analyzed the norovirus within-host diversity and evolution in a cohort of 20 immunocompromised individuals using next-generation sequencing (NGS) and clone-based sequenci...
Abstract
BMC anesthesiology,
Volume 24, Issue 1, 9 2 2024, Pages 362
The effect of three different nonpharmacological methods on cannulation success during peripheral intravenous catheter placement in the emergency unit: a randomized controlled trial.
Yılmaz E, Yılmaz D
Background: Peripheral intravenous catheterization is frequently performed in emergency units, but it is a procedure which is difficult for healthcare professionals and painful for patients. The primary objective of the present study was to examine the effect on venous dilation, procedure duration and pain severity of local heat, cold and vibration applications performed on the intervention area before peripheral intravenous catheterization in adults. The second objective of the study was to exa...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 11, Issue 10, 7 1 2024, Pages 310
Association between Left Atrial Function and Survival in Systemic Sclerosis.
Giucă A, Galloo X, Meucci MC, Butcher SC, Popescu BA, Jurcuț R, Săftoiu A, Jurcuț C, Groșeanu L, Mușetescu AE, Ahmed S, De Vries-Bouwstra J, Bax JJ, Ajmone Marsan N
Systemic sclerosis (SSc) is a multisystemic autoimmune disorder in which cardiac involvement is frequent and portends negative prognosis. Left ventricular (LV) diastolic dysfunction is one of the most common cardiac alterations in these patients, and left atrial (LA) reservoir strain (ƐR) measurement using speckle tracking echocardiography has been proposed as a novel parameter for a better assessment of LV diastolic function. Therefore, the aim of this study was to test the prognostic value of...
Abstract
Biosensors & bioelectronics,
Volume 267, 5 1 2024, Pages 116838
μREACT: A microfluidic system for rapid evaluation of trans-kingdom interactions.
Huang C, Yang J, Chen S, Han SI, Zhang H, Samuel J, Van Schaik E, de Figueiredo P, Han A
Trans-kingdom interactions between cells play pivotal roles in shaping intricate ecological and biological networks. However, our grasp of these interactions remains incomplete. Specifically, the vast phylogenetic spectrum of microorganisms capable of interacting with a given host cell type remains obscure, primarily due to the absence of efficient, high-throughput, single-cell resolution systems that can rapidly decipher these interactions. Here, we introduce μREACT (Microfluidic system for Rap...
Abstract
Cited 2 times since 2024 (2.1 per year)
source: EuropePMC
Journal of dairy science,
Volume 108, Issue 1, 5 1 2024, Pages 821-834
Risk factors for the introduction of bovine viral diarrhea virus in the context of a mandatory control program in Dutch dairy herds.
Bisschop PIH, Strous EEC, Waldeck HWF, van Duijn L, Mars MH, Santman-Berends IMGA, Wever P, van Schaik G
Bovine viral diarrhea virus (BVDV) is a common viral disease in cattle, causing economic losses in naive herds where the virus is introduced. In the Netherlands, a BVDV control program has been in place from 1998 onward, evolving from voluntary to mandatory participation for dairy herds from April 2018 onward. Participation in the BVDV control program is not mandatory for nondairy farms. The aim of this study was to determine risk factors for new introduction of BVDV into certified BVDV-free her...
Abstract
Veterinaria italiana,
Volume 60, Issue 1, 4 1 2024
Using scenario tree modelling to evaluate the probability of freedom from Enzootic bovine leukosis (EBL) in Italy and Slovenia.
Fanelli A, Baron J, Comin A, Faverjon C, Feliziani F, Guelbenzu-Gonzalo M, Hodnik J, Iscaro C, Knific T, Meletis E, Mincu M, Righi C, Thomas R, Tamba M, Frössling J, Van Schaik G
Documented freedom from disease is paramount for international free trade of animals and animal products. This study describes a scenario tree analysis to estimate the probability of freedom from Enzootic bovine leukosis (EBL) in Italy and Slovenia using information gathered via the data collection tool developed in the COST action project SOUND-control. Data on EBL control programmes (CPs) from 2018 to 2021 were used to build the models. Since animals are only sampled on the farm, one surveilla...
Abstract
Cited 5 times since 2024 (5.2 per year)
source: EuropePMC
Pharmacogenetics and genomics,
Volume 35, Issue 1, 3 1 2024, Pages 1-11
The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation.
Cavallari LH, Hicks JK, Patel JN, Elchynski AL, Smith DM, Bargal SA, Fleck A, Aquilante CL, Killam SR, Lemke L, Ochi T, Ramsey LB, Haidar CE, Ho T, El Rouby N, Monte AA, Allen JD, Beitelshees AL, Bishop JR, Bousman C, Campbell R, Cicali EJ, Cook KJ, Duong B, Tsermpini EE, Girdwood ST, Gregornik DB, Grimsrud KN, Lamb N, Lee JC, Lopez RO, Mazhindu TA, Morris SA, Nagy M, Nguyen J, Pasternak AL, Petry N, van Schaik RHN, Schultz A, Skaar TC, Al Alshaykh H, Stevenson JM, Stone RM, Tran NK, Tuteja S, Woodahl EL, Yuan LC, Lee CR
Pharmacogenetics promises to optimize treatment-related outcomes by informing optimal drug selection and dosing based on an individual's genotype in conjunction with other important clinical factors. Despite significant evidence of genetic associations with drug response, pharmacogenetic testing has not been widely implemented into clinical practice. Among the barriers to broad implementation are limited guidance for how to successfully integrate testing into clinical workflows and limited...
Abstract
Infection and immunity,
Volume 92, Issue 11, 2 1 2024, Pages e0033524
Molecular mechanisms of <i>Coxiella burnetii</i> formalin-fixed cellular vaccine reactogenicity.
Fratzke AP, Szule JA, Butler SM, Schaik EJv, Samuel JE
Local and systemic reactogenic responses to Q-VAX have prevented licensing of this vaccine outside of Australia. These reactogenic responses occur in previously sensitized individuals and have not been well defined at the cellular level, in part because many studies have been done in guinea pigs that have limited molecular tools. We previously characterized a mouse model of reactogenicity where local reaction sites showed an influx of CD8+ and IFNγ-expressing IL17a+ CD4+ T cells consistent with...
Abstract
Cited 5 times since 2024 (5.2 per year)
source: EuropePMC
Journal of vascular surgery. Venous and lymphatic disorders,
Volume 13, Issue 1, 2 1 2024, Pages 101970
Nutcracker syndrome (a Delphi consensus).
Heilijgers F, Gloviczki P, O'Sullivan G, Chavent B, Avgerinos ED, Harth K, Black SA, Erben YM, Rotmans JI, Richards T, Chaer RA, Villalba L, Jayaraj A, Malgor RD, Tripathi RK, Dua A, Murphy E, Rinckenbach S, Vedantham S, Hamming JF, van der Vorst JR
Background: Nutcracker syndrome (NCS) describes the symptomatic compression of the left renal vein between the aorta and superior mesenteric artery. Whereas asymptomatic compression is a common radiological finding, patients with NCS can report a range of symptoms. There are no specific diagnostic criteria and interventions include a range of open surgical and endovascular procedures. Therefore, we wished to develop an international consensus document covering aspects of diagnosis, management, a...
Abstract
NPJ precision oncology,
Volume 8, Issue 1, 2 1 2024, Pages 220
A phenocopy signature of TP53 loss predicts response to chemotherapy.
Bakhtiar H, Sharifi MN, Helzer KT, Shi Y, Bootsma ML, Shang TA, Chrostek MR, Berg TJ, Carson Callahan S, Carreno V, Blitzer GC, West MT, O'Regan RM, Wisinski KB, Sjöström M, Zhao SG
In preclinical studies, p53 loss of function impacts chemotherapy response, but this has not been consistently validated clinically. We trained a TP53-loss phenocopy gene expression signature from pan-cancer clinical samples in the TCGA. In vitro, the TP53-loss phenocopy signature predicted chemotherapy response across cancer types. In a clinical dataset of 3003 breast cancer samples treated with neoadjuvant chemotherapy, the TP53-loss phenocopy samples were 56% more likely to have a pathologic...
Abstract
Cited 3 times since 2024 (3.1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 26, Issue 10, 1 1 2024, Pages euae235
Ventricular arrhythmias in acute heart failure: a clinical consensus statement of the Association for Acute CardioVascular Care, the European Heart Rhythm Association, and the Heart Failure Association of the European Society of Cardiology.
Gorenek B, Wijnmaalen AP, Goette A, Mert GO, Porter B, Gustafsson F, Dan GA, Ector J, Stuehlinger M, Spartalis M, Gosau N, Amir O, Chioncel O
Patients presenting with or alerting emergency networks due to acute heart failure (AHF) form a diverse group with a plethora of symptoms, risks, comorbidities, and aetiologies. During AHF, there is an increased risk of destabilizing the functional substrate and modulatory adding to the risk of ventricular arrhythmias (VAs) already created by the structural substrate. New VAs during AHF have previously identified patients with higher intra-hospital and 60-day morbidity and mortality. Risk strati...
Abstract
JACC. Cardiovascular interventions,
Volume 17, Issue 20, 1 1 2024, Pages 2408-2410
The Promise and Challenges of Pressure-Guided Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension.
Montero-Cabezas JM, Delgado V
Abstract
Giornale italiano di cardiologia (2006),
Volume 25, Issue 10, 1 1 2024, Pages 699-710
[Ten questions about infective endocarditis].
Fortuni F, Ciliberti G, Marsan NA, Delgado V, Franchin L, Magnesa M, Spinelli A, Vitale E, Cangemi S, Cornara S, Gabrielli D, Colivicchi F, Grimaldi M, Oliva F
Infective endocarditis (IE) is an infective process involving the endocardium and, more frequently, the native heart valves, valvular prostheses and cardiac implantable electronic devices. IE can manifest with various non-specific symptoms making the diagnosis challenging. This condition is associated with high in-hospital and long-term mortality. Therefore, it is particularly important to prevent it by implementing an adequate antibiotic prophylaxis especially in patients at high risk undergoin...
Abstract
Cited 2 times since 2024 (2.1 per year)
source: EuropePMC
FASEB journal : official publication of the Federation of American Societies for Experimental Biology,
Volume 38, Issue 20, 1 1 2024, Pages e70087
Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice.
Inia JA, Attema J, de Ruiter C, Menke AL, Caspers MPM, Verschuren L, Wilson M, Arlantico A, Brightbill HD, Jukema JW, van den Hoek AM, Princen HMG, Chen MZ, Morrison MC
Fibroblast growth factor 21 (FGF21) is a promising target for treatment of obesity-associated diseases including metabolic dysfunction-associated steatohepatitis (MASH) and atherosclerosis. We evaluated the effects of the bispecific anti-FGF21-β klotho (KLB) agonist antibody bFKB1 in a preclinical model of MASH and atherosclerosis. Low-density lipoprotein receptor knockout (Ldlr-/-).Leiden mice received a high-fat diet for 20 weeks, followed by treatment with an isotype control antibody or bFKB1...
Abstract
Journal of cardiothoracic surgery,
Volume 19, Issue 1, 1 1 2024, Pages 560
Aortic root replacement for bicuspid aortic valve dysfunction does not impair survival rates.
Dolmaci OB, van Maasakker NE, Poelmann RE, Klautz RJ, Grewal N
Background: Patients with a bicuspid aortic valve carry an increased risk for developing an ascending aortic aneurysm due to intrinsic aortic wall alterations. A lower threshold for aortic surgery may therefore be considered in these patients, especially in those who require aortic valve surgery. This study aimed to compare the outcomes of an isolated aortic valve replacement with that of an aortic root replacement in bicuspid aortic valve patients with an indication for aortic valve surgery. Me...
Abstract
Cited 2 times since 2024 (2.1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 66, Issue 4, 1 1 2024, Pages ezae339
European Association of Cardiothoracic Surgeons future view on robotic cardiac surgery in Europe.
Oosterlinck W, Gianoli M, Palmen M, Folliguet T, Bonatti J, Agnino A, Singh S, Franke U, Modi P, Pereda D, Kempfert J, Navarra E, Suwalski P, Vojacek J, Casselman F, Myers P, Sadaba JR, Melfi F, Hazekamp M, Bavaria J, Beyersdorf F, Milojevic M, Falk V, Cerny S
Abstract
