Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7401 results
Cited 8 times since 2024 (7.6 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 84, Issue 13, 1 1 2024, Pages 1178-1189 Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry. Schweiger V, Cammann VL, Crisci G, Gilhofer T, Schlenker R, Niederseer D, Chen S, Ebrahimi R, Wenzl F, Würdinger M, Citro R, Vecchione C, Gili S, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Jansen T, D'Ascenzo F, Dichtl W, von Lewinski D, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Massoomi M, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Kato K, Ishibashi I, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm M, Maier LS, Pinto FJ, Widimský P, Felix SB, Braun-Dul
Background: The perception of takotsubo syndrome (TTS) has evolved significantly over the years, primarily driven by increased recognition of acute complications and mortality. Objectives: This study aimed to explore temporal trends in demographic patterns, risk factors, clinical presentations, and outcomes in patients with TTS. Methods: Patients diagnosed with TTS between 2004 and 2021 were enrolled from the InterTAK (International Takotsubo) registry. To assess temporal trends, patients were d... Abstract
Cited 6 times since 2024 (5.7 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 84, Issue 11, 1 1 2024, Pages 994-1006 Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome. Zahger D, Schwartz GG, Du W, Szarek M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Jukema JW, Kiss RG, Harrington RA, Moriarty PM, Scemama M, Manvelian G, Pordy R, White HD, Zeiher AM, Fazio S, Geba GP, Steg PG, ODYSSEY OUTCOMES Investigators
Background: It is unknown whether clinical benefit of proprotein convertase subtilisin/kexin type 9 inhibitors is associated with baseline or on-treatment triglyceride concentrations. Objectives: This study sought to examine relations between triglyceride levels and the effect of alirocumab vs placebo on cardiovascular outcomes using prespecified and post hoc analyses of the ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab)... Abstract
Cited 2 times since 2024 (1.9 per year) source: EuropePMC
Neural computation, Volume 36, Issue 10, 1 1 2024, Pages 1939-2029 Electrical Signaling Beyond Neurons. Monk T, Dennler N, Ralph N, Rastogi S, Afshar S, Urbizagastegui P, Jarvis R, van Schaik A, Adamatzky A
Neural action potentials (APs) are difficult to interpret as signal encoders and/or computational primitives. Their relationships with stimuli and behaviors are obscured by the staggering complexity of nervous systems themselves. We can reduce this complexity by observing that "simpler" neuron-less organisms also transduce stimuli into transient electrical pulses that affect their behaviors. Without a complicated nervous system, APs are often easier to understand as signal/response mec... Abstract
Cited 8 times since 2024 (7.6 per year) source: EuropePMC
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, Volume 29, Issue 39, 1 1 2024 Increased circulation of GII.17 noroviruses, six European countries and the United States, 2023 to 2024. Chhabra P, Wong S, Niendorf S, Lederer I, Vennema H, Faber M, Nisavanh A, Jacobsen S, Williams R, Colgan A, Yandle Z, Garvey P, Al-Hello H, Ambert-Balay K, Barclay L, de Graaf M, Celma C, Breuer J, Vinjé J, Douglas A
We report an increase in GII.17 norovirus outbreaks and sporadic infections of acute gastroenteritis in Austria, Germany, France, Ireland, the Netherlands, England and the United States during the 2023/24 season. A decrease in GII.4 coincided with GII.17 prevalence increasing to between 17% and 64% of all GII detections. Overall, 84% of the GII.17 strains clustered closely with strains first reported in Romania in 2021 and two new sub-lineages were identified. Norovirus surveillance and molecula... Abstract
Cited 786 times since 2024 (745.9 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3314-3414 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Van Gelder IC, Rienstra M, Bunting KV, Casado-Arroyo R, Caso V, Crijns HJGM, De Potter TJR, Dwight J, Guasti L, Hanke T, Jaarsma T, Lettino M, Løchen ML, Lumbers RT, Maesen B, Mølgaard I, Rosano GMC, Sanders P, Schnabel RB, Suwalski P, Svennberg E, Tamargo J, Tica O, Traykov V, Tzeis S, Kotecha D, ESC Scientific Document Group
Cited 11 times since 2024 (10.4 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 25, Issue 10, 1 1 2024, Pages 1351-1359 Pericoronary adipose tissue for predicting long-term outcomes. van Rosendael SE, Kamperidis V, Maaniitty T, de Graaf MA, Saraste A, McKay-Goodall GE, Jukema JW, Knuuti J, Bax JJ
Aims: Pericoronary adipose tissue (PCAT) attenuation obtained by coronary computed tomography angiography (CCTA) has been associated with coronary inflammation and outcomes. Whether PCAT attenuation is predictive of major adverse cardiac events (MACE) during long-term follow-up is unknown. Methods and results: Symptomatic patients with coronary artery disease (CAD) who underwent CCTA were included, and clinical outcomes were evaluated. PCAT was measured at all lesions for all three major coronar... Abstract
Cited 186 times since 2024 (176.5 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3538-3700 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases. Mazzolai L, Teixido-Tura G, Lanzi S, Boc V, Bossone E, Brodmann M, Bura-Rivière A, De Backer J, Deglise S, Della Corte A, Heiss C, Kałużna-Oleksy M, Kurpas D, McEniery CM, Mirault T, Pasquet AA, Pitcher A, Schaubroeck HAI, Schlager O, Sirnes PA, Sprynger MG, Stabile E, Steinbach F, Thielmann M, van Kimmenade RRJ, Venermo M, Rodriguez-Palomares JF, ESC Scientific Document Group
Cited 713 times since 2024 (676.6 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3415-3537 2024 ESC Guidelines for the management of chronic coronary syndromes. Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, Banning AP, Budaj A, Buechel RR, Chiariello GA, Chieffo A, Christodorescu RM, Deaton C, Doenst T, Jones HW, Kunadian V, Mehilli J, Milojevic M, Piek JJ, Pugliese F, Rubboli A, Semb AG, Senior R, Ten Berg JM, Van Belle E, Van Craenenbroeck EM, Vidal-Perez R, Winther S, ESC Scientific Document Group
Cited 1 times since 2024 (0.9 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 37, Issue 12, 1 1 2024, Pages 1188-1190.e3 Right Ventricular to Pulmonary Artery Coupling and Prognosis in Transthyretin Cardiac Amyloidosis. Meucci MC, Laenens D, Lillo R, Lombardo A, Burzotta F, Stassen J, Debonnaire P, Claeys M, Donal E, Droogmans S, Cosyns B, Jurcut R, Pinto FJ, Brito D, Yedidya I, Van De Heyning C, Sturkenboom N, Graziani F, Ajmone Marsan N
Cited 1 times since 2024 (0.9 per year) source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research, Volume 30, Issue 18, 1 1 2024, Pages 4227-4239 Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment. Chelushkin MA, van Dorp J, van Wilpe S, Seignette IM, Mellema JJ, Alkemade M, Gil-Jimenez A, Peters D, Brugman W, Stockem CF, Hooijberg E, Broeks A, van Rhijn BWG, Mertens LS, van der Heijden AG, Mehra N, van Montfoort ML, Wessels LFA, Vis DJ, van der Heijden MS
Purpose: Platinum-based chemotherapy and immune checkpoint inhibitors are key components of systemic treatment for muscle-invasive and advanced urothelial cancer. The ideal integration of these two treatment modalities remains unclear as clinical trials have led to inconsistent results. Modulation of the tumor-immune microenvironment by chemotherapy is poorly characterized. We aimed to investigate this modulation, focusing on potential clinical implications for immune checkpoint inhibitor respon... Abstract
Cited 10 times since 2024 (9.5 per year) source: EuropePMC
The New England journal of medicine, Volume 392, Issue 5, 31 5 2024, Pages 438-449 Continuation versus Interruption of Oral Anticoagulation during TAVI. van Ginkel DJ, Bor WL, Aarts HM, Dubois C, De Backer O, Rooijakkers MJP, Rosseel L, Veenstra L, van der Kley F, van Bergeijk KH, Van Mieghem NM, Agostoni P, Voskuil M, Schotborgh CE, IJsselmuiden AJJ, Van Der Heyden JAS, Hermanides RS, Barbato E, Mylotte D, Fabris E, Frambach P, Dujardin K, Ferdinande B, Peper J, Rensing BJWM, Timmers L, Swaans MJ, Brouwer J, Nijenhuis VJ, Overduin DC, Adriaenssens T, Kobari Y, Vriesendorp PA, Montero-Cabezas JM, El Jattari H, Halim J, Van den Branden BJL, Leonora R, Vanderheyden M, Lauterbach M, Wykrzykowska JJ, van 't Hof AWJ, van Royen N, Tijssen JGP, Delewi R, Ten Berg JM, POPular PAUSE TAVI Investigators, POPular PAUSE TAVI Investigators
Background: One third of patients undergoing transcatheter aortic-valve implantation (TAVI) have an indication for oral anticoagulation owing to concomitant diseases. Interruption of oral anticoagulation during TAVI may decrease the risk of bleeding, whereas continuation may decrease the risk of thromboembolism. Methods: We conducted an international, open-label, randomized, noninferiority trial involving patients who were receiving oral anticoagulants and were planning to undergo TAVI. Patients... Abstract
Cited 10 times since 2024 (9.4 per year) source: EuropePMC
Nature communications, Volume 15, Issue 1, 30 5 2024, Pages 7551 Time-series sewage metagenomics distinguishes seasonal, human-derived and environmental microbial communities potentially allowing source-attributed surveillance. Becsei Á, Fuschi A, Otani S, Kant R, Weinstein I, Alba P, Stéger J, Visontai D, Brinch C, de Graaf M, Schapendonk CME, Battisti A, De Cesare A, Oliveri C, Troja F, Sironen T, Vapalahti O, Pasquali F, Bányai K, Makó M, Pollner P, Merlotti A, Koopmans M, Csabai I, Remondini D, Aarestrup FM, Munk P
Sewage metagenomics has risen to prominence in urban population surveillance of pathogens and antimicrobial resistance (AMR). Unknown species with similarity to known genomes cause database bias in reference-based metagenomics. To improve surveillance, we seek to recover sewage genomes and develop a quantification and correlation workflow for these genomes and AMR over time. We use longitudinal sewage sampling in seven treatment plants from five major European cities to explore the utility of ca... Abstract
Research and practice in thrombosis and haemostasis, Volume 8, Issue 6, 30 5 2024, Pages 102558 Erratum to 'Performance of Risk Scores in Predicting Major Bleeding in Left Ventricular Assist Device (LVAD) Recipients: a Comparative External Validation. '[Res Pract Thromb Haemost. 2024;8:e102437]. van der Horst SFB, de Jong Y, van Rein N, Jukema JW, Palmen M, Janssen E, Bonneville EF, Klok FA, Huisman MV, Tops LF, den Exter PL
[This corrects the article DOI: 10.1016/j.rpth.2024.102437.]. Abstract
Cited 3 times since 2024 (2.8 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 104, Issue 4, 29 5 2024, Pages 655-663 Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one-year clinical outcomes. Oliveri F, van Oort MJH, Al Amri I, Bingen BO, Claessen BE, Dimitriu-Leen AC, Kefer J, Girgis H, Vossenberg T, van der F, Jukema JW, Montero-Cabezas JM
Background: Calcification within chronic total occlusions (CTO) is strongly associated with worse outcomes. Despite the excellent success and safety of intravascular lithotripsy (IVL) in heavily calcified lesions, evidence in CTO remains scarce. Aim: This study aimed to evaluate the procedural and long-term clinical outcomes of IVL in heavily calcified CTO. Methods: Patients who underwent IVL between 2019 and 2024 from an ongoing prospective multicenter registry were eligible for inclusion. Pati... Abstract
Journal of the American Heart Association, Volume 13, Issue 17, 29 5 2024, Pages e034760 Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lifelines Cohort Study, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB
Background: Ventricular repolarization time (ECG QT and JT intervals) is associated with malignant arrhythmia. Genome-wide association studies have identified 230 independent loci for QT and JT; however, 50% of their heritability remains unexplained. Previous work supports a causal effect of lower serum calcium concentrations on longer ventricular repolarization time. We hypothesized calcium interactions with QT and JT variant associations could explain a proportion of the missing heritability.... Abstract
Journal of cardiovascular development and disease, Volume 11, Issue 9, 27 4 2024, Pages 264 Exploring Sex Differences in Pain Manifestation of Coronary Artery Disease through Mendelian Randomization. Methorst R, Jongbloed MRM, Noordam R, DeRuiter MC
Pain manifestation following coronary artery disease (CAD) disease differs between men and women. Here, we aimed to provide evidence favoring possible differences in pain manifestation between men and women following CAD using Mendelian randomization (MR). We used summary-level data from sex-stratified genome-wide association studies on CAD and self-reported and clinically diagnosed chest, neck and shoulder, back, and facial pain using data from the UK Biobank cohort (N > 450,000) followed by... Abstract
Cited 2 times since 2024 (1.9 per year) source: EuropePMC
European journal of heart failure, Volume 26, Issue 10, 27 4 2024, Pages 2173-2182 Heart failure risk assessment in patients with hypertrophic cardiomyopathy based on the H<sub>2</sub>FPEF score. Laenens D, Zegkos T, Kamperidis V, Wong RCC, Li TY, Sia CH, Kong WKF, Efthimiadis G, Poh KK, Ziakas A, Bax JJ, Ajmone Marsan N
Aims: The aim of this study was to investigate whether the H2FPEF score, which was developed to improve the diagnosis of heart failure (HF) with preserved ejection fraction, is associated with HF outcomes in patients with hypertrophic cardiomyopathy (HCM). Methods and results: Patients with HCM and preserved left ventricular ejection fraction (LVEF ≥50%) were included from a multicentre registry and the H2FPEF score was calculated. Patients were divided into three groups: low (0-1), intermediate... Abstract
Cited 9 times since 2024 (8.4 per year) source: EuropePMC
Nature biomedical engineering, Volume 8, Issue 8, 26 4 2024, Pages 941-962 Standardizing designed and emergent quantitative features in microphysiological systems. Nahon DM, Moerkens R, Aydogmus H, Lendemeijer B, Martínez-Silgado A, Stein JM, Dostanić M, Frimat JP, Gontan C, de Graaf MNS, Hu M, Kasi DG, Koch LS, Le KTT, Lim S, Middelkamp HHT, Mooiweer J, Motreuil-Ragot P, Niggl E, Pleguezuelos-Manzano C, Puschhof J, Revyn N, Rivera-Arbelaez JM, Slager J, Windt LM, Zakharova M, van Meer BJ, Orlova VV, de Vrij FMS, Withoff S, Mastrangeli M, van der Meer AD, Mummery CL
Microphysiological systems (MPSs) are cellular models that replicate aspects of organ and tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide physiological mechanical cues to cells, include fluid flow and can be interlinked (hence, they are often referred to as microfluidic tissue chips or organs-on-chips). Here, by means of examples of MPSs of the vascular system, intestine, brain and heart, we advocate for the development of standards that allow for compa... Abstract
The Science of the total environment, Volume 951, 25 4 2024, Pages 175620 Corrigendum to "Accumulation of airborne microplastics on leaves of different tree species in the urban environment" [Sci. Total Environ. Volume 948, 20 October 2024, page 174907]. Leitão IA, Van Schaik L, Iwasaki S, Ferreira AJD, Geissen V
Cited 2 times since 2024 (1.9 per year) source: EuropePMC
British journal of cancer, Volume 131, Issue 7, 24 4 2024, Pages 1224-1236 IMPRESS: Improved methylation profiling using restriction enzymes and smMIP sequencing, combined with a new biomarker panel, creating a multi-cancer detection assay. Vandenhoeck J, Neefs I, Vanpoucke T, Ibrahim J, Suls A, Peeters D, Schepers A, Hoischen A, Fransen E, Peeters M, Van Camp G, Op de Beeck K
Background: Despite the worldwide progress in cancer diagnostics, more sensitive diagnostic biomarkers are needed. The methylome has been extensively investigated in the last decades, but a low-cost, bisulfite-free detection method for multiplex analysis is still lacking. Methods: We developed a methylation detection technique called IMPRESS, which combines methylation-sensitive restriction enzymes and single-molecule Molecular Inversion Probes. We used this technique for the development of a mu... Abstract