Research

Publications

Below you can find a list of our published research.

6128 results

Cited 34 times since 2020 (7.8 per year) source: EuropePMC

European heart journal, Volume 41, Issue 43, 1 1 2020, Pages 4181-4187 Long-term clinical outcomes of losartan in patients with Marfan syndrome: follow-up of the multicentre randomized controlled COMPARE trial. van Andel MM, Indrakusuma R, Jalalzadeh H, Balm R, Timmermans J, Scholte AJ, van den Berg MP, Zwinderman AH, Mulder BJM, de Waard V, Groenink M

Aims: The COMPARE trial showed a small but significant beneficial effect of 3-year losartan treatment on aortic root dilatation rate in adults with Marfan syndrome (MFS). However, no significant effect was found on clinical endpoints, possibly due to a short follow-up period. The aim of the current study was therefore to investigate the long-term clinical outcomes after losartan treatment. Methods and results: In the original COMPARE study (inclusion 2008-2009), adult patients with MFS (n = 233)... Abstract

Cited 9 times since 2020 (2.1 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 14, Issue 4, 28 4 2020, Pages 756-765 Insufficient Mitral Leaflet Remodeling in Relation to Annular Dilation and Risk of Residual Mitral Regurgitation After MitraClip Implantation. Hirasawa K, Namazi F, Milhorini Pio S, Vo NM, Ajmone Marsan N, Bax JJ, Delgado V

Objectives: The purpose of this study was to determine whether the mitral valve (MV) total leaflet area (TLA)-to-mitral annular area (MAA) (TLA/MAA) ratio measured using 3-dimensional (3D) transesophageal echocardiography (TEE) was associated with residual mitral regurgitation (MR) after MitraClip implantation in patients with secondary MR. Background: The factors influencing the results of MitraClip implantation for secondary MR are controversial. This study hypothesized that insufficient remod... Abstract

Cited 9 times since 2020 (2.1 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 7, Issue 2, 28 4 2020, Pages 197-205 Mini-, Micro-, and Conventional Electrodes: An in Vivo Electrophysiology and Ex Vivo Histology Head-to-Head Comparison. Glashan CA, Beukers HKC, Tofig BJ, Tao Q, Blom S, Mertens B, Kristiansen SB, Zeppenfeld K

Objectives: This study sought to assess the relative effect of catheter, tissue, and catheter-tissue parameters, on the ability to determine the amount of viable myocardium in vivo. Background: Although multiple variables impact bipolar voltages (BVs), electrode size, interelectrode spacing, and directional dependency are of particular interest with the development of catheters incorporating mini and microelectrodes. Methods: Nine swine with early reperfusion myocardial infarctions were mapped u... Abstract

Cited 4 times since 2020 (0.9 per year) source: EuropePMC

Journal of gastrointestinal and liver diseases : JGLD, Volume 29, Issue 4, 27 4 2020, Pages 617-622 Evaluation of the Association between Programmed Cell Death-1 Gene Polymorphisms and Hepatocellular Carcinoma Susceptibility in Turkish Subjects. A Pilot Study. Demirci AF, Demirtas CO, Eren F, Yilmaz D, Keklikkiran C, Ozdogan OC, Gunduz F

Background and aims: Programmed cell death-1 (PD-1) has a vital role in regulating T-cell function, and immune escape mechanism of cancer cells. It was shown that there could be a relationship between single nucleotide polymorphisms (SNPs) in the PD-1 gene and susceptibility to hepatocellular carcinoma (HCC) based on various studies. We aimed to investigate the role of three SNPs within the PD-1 gene in susceptibility to HCC in the Turkish population. Methods: Single nucleotide polymorphisms of... Abstract

Cited 10 times since 2020 (2.3 per year) source: EuropePMC

Cardiovascular drugs and therapy, Volume 36, Issue 4, 21 3 2020, Pages 739-748 The Use of Angiotensin II for the Treatment of Post-cardiopulmonary Bypass Vasoplegia. Papazisi O, Palmen M, Danser AHJ

Purpose: Vasoplegia is a common complication after cardiac surgery and is related to the use of cardiopulmonary bypass (CPB). Despite its association with increased morbidity and mortality, no consensus exists in terms of its treatment. In December 2017, angiotensin II (AII) was approved by the Food and Drug Administration (FDA) for use in vasodilatory shock; however, except for the ATHOS-3 trial, its use in vasoplegic patients that underwent cardiac surgery on CPB has mainly been reported in ca... Abstract

Cited 1 times since 2020 (0.2 per year) source: EuropePMC

Journal of cardiac surgery, Volume 35, Issue 12, 21 3 2020, Pages 3477-3485 Prosthesis-patient mismatch after mitral valve replacement: A pooled meta-analysis of Kaplan-Meier-derived individual patient data. Tomšič A, Arabkhani B, Schoones JW, Etnel JRG, Marsan NA, Klautz RJM, Palmen M

Objective: The hemodynamic effect and early and late survival impact of prosthesis-patient mismatch (PPM) after mitral valve replacement remains insufficiently explored. Methods: Pubmed, Embase, Web of Science, and Cochrane Library databases were searched for English language original publications. The search yielded 791 potentially relevant studies. The final review and analysis included 19 studies compromising 11,675 patients. Results: Prosthetic effective orifice area was calculated with the... Abstract

Cited 4 times since 2020 (0.9 per year) source: EuropePMC

International journal of cardiology, Volume 326, 21 3 2020, Pages 88-91 The aortic root in repaired tetralogy of Fallot: Serial measurements and impact of losartan treatment. Woudstra OI, Ghanam A, Vliegen HW, van Dijk APJ, van Melle JP, Groenink M, Meijboom FJ, Post MC, Mulder BJM, Bouma BJ, Bokma JP

Background: Aortic root dilatation is common in adults with repaired tetralogy of Fallot (rTOF) and might lead to aortic dissection. However, little is known on progression of aortic dilatation and the effect of pharmaceutical treatment. This study aims to determine factors associated with aortic growth and investigate effects of losartan. Methods and results: We performed a prespecified analysis from the 1:1 randomized, double-blind REDEFINE trial. Aortic root diameters were measured at baselin... Abstract

Cited 1 times since 2020 (0.2 per year) source: EuropePMC

European heart journal. Case reports, Volume 4, Issue 5, 15 3 2020, Pages 1-3 Pulmonary hypertension causing left main coronary artery compression. Verheijen DBH, Meijer FMM, Kiès P, Egorova AD

Abstract

Cited 7 times since 2020 (1.6 per year) source: EuropePMC

Peptides, Volume 135, 13 2 2020, Pages 170424 Interplay of circulating leptin and obesity in cognition and cerebral volumes in older adults. Zonneveld MH, Noordam R, van der Grond J, van Heemst D, Mooijaart SP, Sabayan B, Jukema JW, Trompet S

We aimed to investigate whether circulating leptin and body mass index (BMI) associate independently with cognitive function (decline) and brain volumes using magnetic resonance imaging (MRI) in older individuals at risk of cardiovascular disease. We studied the cross-sectional and longitudinal associations in participants enrolled in the PROSPER study (Prospective Study of Pravastatin in the Elderly at Risk). Cognitive function was tested at baseline and repeated during a mean follow-up time of... Abstract

Nature communications, Volume 11, Issue 1, 8 2 2020, Pages 5141 Author Correction: Straightforward preparation of supramolecular Janus nanorods by hydrogen bonding of end-functionalized polymers. Han S, Pensec S, Yilmaz D, Lorthioir C, Jestin J, Guigner JM, Niepceron F, Rieger J, Stoffelbach F, Nicol E, Colombani O, Bouteiller L

An amendment to this paper has been published and can be accessed via a link at the top of the paper. Abstract

Cited 11 times since 2020 (2.5 per year) source: EuropePMC

The journal of allergy and clinical immunology. In practice, Volume 9, Issue 3, 7 1 2020, Pages 1389-1392.e2 Long-term follow-up and treatment outcomes of conjunctivitis during dupilumab treatment in patients with moderate-to-severe atopic dermatitis. Achten R, Bakker D, Ariens L, Lans A, Thijs J, van der Schaft J, de Boer J, Balak D, de Graaf M, van Luijk C, de Bruin-Weller M

Abstract

Cited 89 times since 2020 (20.2 per year) source: EuropePMC

Frontiers in immunology, Volume 11, 6 1 2020, Pages 575047 Increased Plasma Heparanase Activity in COVID-19 Patients. Buijsers B, Yanginlar C, de Nooijer A, Grondman I, Maciej-Hulme ML, Jonkman I, Janssen NAF, Rother N, de Graaf M, Pickkers P, Kox M, Joosten LAB, Nijenhuis T, Netea MG, Hilbrands L, van de Veerdonk FL, Duivenvoorden R, de Mast Q, van der Vlag J

Reports suggest a role of endothelial dysfunction and loss of endothelial barrier function in COVID-19. It is well established that the endothelial glycocalyx-degrading enzyme heparanase contributes to vascular leakage and inflammation. Low molecular weight heparins (LMWH) serve as an inhibitor of heparanase. We hypothesize that heparanase contributes to the pathogenesis of COVID-19, and that heparanase may be inhibited by LMWH. To test this hypothesis, heparanase activity and heparan sulfate le... Abstract

Cited 12 times since 2020 (2.7 per year) source: EuropePMC

Scientific reports, Volume 10, Issue 1, 6 1 2020, Pages 16601 Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice. Pluijmert NJ, Bart CI, Bax WH, Quax PHA, Atsma DE

Many novel therapies to treat myocardial infarction (MI), yielding promising results in animal models, nowadays failed in clinical trials for several reasons. The most used animal MI model is based on permanent ligation of the left anterior descending (LAD) coronary artery in healthy mice resulting in transmural MI, while in clinical practice reperfusion is usually accomplished by primary percutaneous coronary interventions (PCI) limiting myocardial damage and inducing myocardial ischemia-reperf... Abstract

Cited 1 times since 2020 (0.2 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 106, Issue 24, 5 1 2020, Pages 1950 Neoaortic growth rate and diameter as risk factors for neoaortic valve regurgitation after arterial switch operation. van der Palen RL, Baart SJ, van Geloven N, Hazekamp MG, Blom NA

Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 3, 2 1 2020, Pages 173-174 Broad complex tachycardia; never judge a book by its cover. Regeer MV, Tops LF, de Riva Silva M

Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 3, 2 1 2020, Pages 168-171 Broad complex tachycardia; never judge a book by its cover. Regeer MV, Tops LF, de Riva Silva M

Abstract

Cited 35 times since 2020 (7.9 per year) source: EuropePMC

European journal of heart failure, Volume 22, Issue 12, 2 1 2020, Pages 2290-2309 The cancer patient and cardiology. Zamorano JL, Gottfridsson C, Asteggiano R, Atar D, Badimon L, Bax JJ, Cardinale D, Cardone A, Feijen EAM, Ferdinandy P, López-Fernández T, Gale CP, Maduro JH, Moslehi J, Omland T, Plana Gomez JC, Scott J, Suter TM, Minotti G

Advances in cancer treatments have improved clinical outcomes, leading to an increasing population of cancer survivors. However, this success is associated with high rates of short- and long-term cardiovascular (CV) toxicities. The number and variety of cancer drugs and CV toxicity types make long-term care a complex undertaking. This requires a multidisciplinary approach that includes expertise in oncology, cardiology and other related specialties, and has led to the development of the cardio-o... Abstract

Cited 15 times since 2020 (3.4 per year) source: EuropePMC

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, Volume 59, Issue 1, 1 1 2020, Pages 145-298 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias. Cronin EM, Bogun FM, Maury P, Peichl P, Chen M, Namboodiri N, Aguinaga L, Leite LR, Al-Khatib SM, Anter E, Berruezo A, Callans DJ, Chung MK, Cuculich P, d'Avila A, Deal BJ, Bella PD, Deneke T, Dickfeld TM, Hadid C, Haqqani HM, Kay GN, Latchamsetty R, Marchlinski F, Miller JM, Nogami A, Patel AR, Pathak RK, Saenz Morales LC, Santangeli P, Sapp JL, Sarkozy A, Soejima K, Stevenson WG, Tedrow UB, Tzou WS, Varma N, Zeppenfeld K

Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and treat them. The field of catheter ablation has progressed with the development of new methods and tools, and with the publication of large clinical trials. There... Abstract

Cited 5 times since 2020 (1.1 per year) source: EuropePMC

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, Volume 59, Issue 1, 1 1 2020, Pages 81-133 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: Executive summary. Cronin EM, Bogun FM, Maury P, Peichl P, Chen M, Namboodiri N, Aguinaga L, Leite LR, Al-Khatib SM, Anter E, Berruezo A, Callans DJ, Chung MK, Cuculich P, d'Avila A, Deal BJ, Della Bella P, Deneke T, Dickfeld TM, Hadid C, Haqqani HM, Kay GN, Latchamsetty R, Marchlinski F, Miller JM, Nogami A, Patel AR, Pathak RK, Saenz Morales LC, Santangeli P, Sapp JL, Sarkozy A, Soejima K, Stevenson WG, Tedrow UB, Tzou WS, Varma N, Zeppenfeld K

Cited 6 times since 2020 (1.4 per year) source: EuropePMC

Alcohol and alcoholism (Oxford, Oxfordshire), Volume 55, Issue 6, 1 1 2020, Pages 660-666 L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms: Nausea, Headache, Stress and Anxiety. Eriksson CJP, Metsälä M, Möykkynen T, Mäkisalo H, Kärkkäinen O, Palmén M, Salminen JE, Kauhanen J

Aims: Alcohol-related hangover symptoms: nausea, headache, stress and anxiety cause globally considerable amount of health problems and economic losses. Many of these harmful effects are produced by alcohol and its metabolite, acetaldehyde, which also is a common ingredient in alcohol beverages. The aim of the present study is to investigate the effect of the amino acid L-cysteine on the alcohol/acetaldehyde related aftereffects. Methods: Voluntary healthy participants were recruited through adv... Abstract