Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6883 results
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
Clinical kidney journal, Volume 13, Issue 6, 23 4 2019, Pages 1077-1082 Mortality after amputation in dialysis patients is high but not modified by diabetes status. Schroijen MA, van Diepen M, Hamming JF, Dekker FW, Dekkers OM
Background: Survival among dialysis patients with diabetes mellitus (DM) is inferior to survival of non-diabetic dialysis patients, probably due to the higher prevalence of diabetes-related comorbid conditions. One could hypothesize that these comorbid conditions also contribute to a decreased survival after amputation in diabetic patients compared with non-diabetic patients on dialysis. Methods: Data were collected from the Netherlands Cooperative Study on the Adequacy of Dialysis, a multicentr... Abstract
Cited 7 times since 2019 (1.3 per year) source: EuropePMC
Diabetes, Volume 68, Issue 12, 19 3 2019, Pages 2327-2336 Genome-Wide Association Study on the Early-Phase Insulin Response to a Liquid Mixed Meal: Results From the NEO Study. Li-Gao R, Carlotti F, de Mutsert R, van Hylckama Vlieg A, de Koning EJP, Jukema JW, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO
Early-phase insulin secretion is a determinant of postprandial glucose homeostasis. In this study, we aimed to identify novel genetic variants associated with the early-phase insulin response to a liquid mixed meal by a genome-wide association study using a discovery and replication design embedded in the Netherlands Epidemiology of Obesity (NEO) study. The early-phase insulin response was defined as the difference between the natural logarithm-transformed insulin concentrations of the postprand... Abstract
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 11 Pt 1, 18 3 2019, Pages 2266-2267 Absolute Stress Myocardial Blood Flow After Coronary CT Angiography Guides Referral to Invasive Angiography. Stenström I, Maaniitty T, Uusitalo V, Ukkonen H, Kajander S, Mäki M, Nammas W, Bax JJ, Knuuti J, Saraste A
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
Pediatric allergy, immunology, and pulmonology, Volume 32, Issue 3, 17 3 2019, Pages 121-127 Levels of Soluble Urokinase Plasminogen Activator Receptor in Pediatric Lower Respiratory Tract Infections. Çitlenbik H, Ulusoy E, Er A, Çağlar A, Akgül F, Küme T, Yılmaz D, Duman M
Background: Lower respiratory tract infections (LTRIs) are the most common cause of pediatric emergency department visits and are associated with significant morbidity and mortality. The aim of this study was to evaluate the soluble urokinase plasminogen activator receptor (suPAR) levels in pediatric patients with LRTIs and to investigate the correlation of suPAR with disease severity. Methods: This is a prospective case-control study of children with LTRIs. Demographic data, diagnoses, vital si... Abstract
Cited 5 times since 2019 (0.9 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 12, Issue 9, 17 3 2019, Pages e008737 Point of Care Clinical Risk Score to Improve the Negative Diagnostic Utility of an Agatston Score of Zero: Averting the Need for Coronary Computed Tomography Angiography. Alshahrani AM, Mahmood H, Wells GA, Hossain A, Rybicki FJ, Achenbach S, Al-Mallah MH, Andreini D, Bax JJ, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, Pontone G, Raff G, Rubinshtein R, Shaw LJ, Villines TC, Lin FY, Min JK, Chow BJ
Background: Coronary artery calcification is a marker of underlying atherosclerotic vascular disease. The absence of coronary artery calcification is associated with a low prevalence of obstructive coronary artery disease (CAD), but it cannot be ruled out completely. We sought to develop a clinical tool that can be added to Agatston score of zero to rule out obstructive CAD with high accuracy. Methods: We developed a clinical score retrospectively from a cohort of 4903 consecutive patients with... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 28, Issue 4, 16 3 2019, Pages 1707-1714 Relationship between coronary artery calcification and myocardial ischemia on computed tomography myocardial perfusion in patients with stable chest pain. El Mahdiui M, Smit JM, van Rosendael AR, Jukema JW, Bax JJ, Scholte AJHA
Background: Coronary artery calcium (CAC) score has shown to provide incremental prognostic information when added to the Framingham risk score. Although the relation between CAC and myocardial ischemia has been evaluated, there has been little evaluation of the relationship between CAC score and inducible myocardial ischemia on computed tomography myocardial perfusion (CTP). Methods and results: Patients who were referred with stable chest pain from the outpatient clinic and who underwent non-c... Abstract
Cited 17 times since 2019 (3.1 per year) source: EuropePMC
European journal of heart failure, Volume 21, Issue 11, 16 3 2019, Pages 1426-1433 Safety and efficacy of the partial adenosine A1 receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced ejection fraction: a phase IIb, randomized, double-blind, placebo-controlled trial. Voors AA, Bax JJ, Hernandez AF, Wirtz AB, Pap AF, Ferreira AC, Senni M, van der Laan M, Butler J, PANTHEON Investigators
Aims: Neladenoson bialanate is a partial adenosine A1 receptor agonist with demonstrated beneficial effects on cardiac function in animal models. We aimed to assess the dose-response effect of neladenoson bialanate on cardiac structure and function, clinical outcome, and safety in patients with heart failure (HF) with reduced ejection fraction (HFrEF). Methods and results: PANTHEON was a dose-finding, phase IIb, randomized, double-blind, placebo-controlled trial conducted in 92 centres in 11 cou... Abstract
Cited 150 times since 2019 (27.3 per year) source: EuropePMC
Circulation, Volume 140, Issue 14, 12 2 2019, Pages 1156-1169 Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey. Iung B, Delgado V, Rosenhek R, Price S, Prendergast B, Wendler O, De Bonis M, Tribouilloy C, Evangelista A, Bogachev-Prokophiev A, Apor A, Ince H, Laroche C, Popescu BA, Piérard L, Haude M, Hindricks G, Ruschitzka F, Windecker S, Bax JJ, Maggioni A, Vahanian A, EORP VHD II Investigators
Background: Valvular heart disease (VHD) is an important cause of mortality and morbidity and has been subject to important changes in management. The VHD II survey was designed by the EURObservational Research Programme of the European Society of Cardiology to analyze actual management of VHD and to compare practice with guidelines. Methods: Patients with severe native VHD or previous valvular intervention were enrolled prospectively across 28 countries over a 3-month period in 2017. Indication... Abstract
Cited 22 times since 2019 (4 per year) source: EuropePMC
Circulation, Volume 140, Issue 19, 2 1 2019, Pages 1578-1589 Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. Roe MT, Li QH, Bhatt DL, Bittner VA, Diaz R, Goodman SG, Harrington RA, Jukema JW, Lopez-Jaramillo P, Lopes RD, Louie MJ, Moriarty PM, Szarek M, Vogel R, White HD, Zeiher AM, Baccara-Dinet MT, Steg PG, Schwartz GG
Background: The 2018 US cholesterol management guidelines recommend additional lipid-lowering therapies for secondary prevention in patients with low-density lipoprotein cholesterol ≥70 mg/dL or non-high-density lipoprotein cholesterol ≥100 mg/dL despite maximum tolerated statin therapy. Such patients are considered at very high risk (VHR) based on a history of >1 major atherosclerotic cardiovascular disease (ASCVD) event or a single ASCVD event and multiple high-risk conditions. We investiga... Abstract
Cited 7 times since 2019 (1.3 per year) source: EuropePMC
European journal of preventive cardiology, Volume 27, Issue 3, 2 1 2019, Pages 272-280 Familial occurrence of mitral regurgitation in patients with mitral valve prolapse undergoing mitral valve surgery. Hiemstra YL, Wijngaarden ALV, Bos MW, Schalij MJ, Klautz RJ, Bax JJ, Delgado V, Barge-Schaapveld DQ, Marsan NA
Background: Initial studies have suggested the familial clustering of mitral valve prolapse, but most of them were either community based among unselected individuals or applied non-specific diagnostic criteria. Therefore little is known about the familial distribution of mitral regurgitation in a referral-type population with a more severe mitral valve prolapse phenotype. The objective of this study was to evaluate the presence of familial mitral regurgitation in patients undergoing surgery for... Abstract
Cited 6 times since 2019 (1.1 per year) source: EuropePMC
Interactive cardiovascular and thoracic surgery, Volume 29, Issue 3, 1 1 2019, Pages 461-468 A 45-year experience with the Fontan procedure: tachyarrhythmia, an important sign for adverse outcome. Rijnberg FM, Blom NA, Sojak V, Bruggemans EF, Kuipers IM, Rammeloo LAJ, Jongbloed MRM, Bouma BJ, Hazekamp MG
Objectives: This study aims to evaluate our 45-year experience with the Fontan procedure and to identify risk factors for late mortality and morbidity. Methods: Demographic, preoperative, perioperative and postoperative characteristics were retrospectively collected for all patients who underwent a Fontan procedure in a single centre between 1972 and 2016. Results: The study included 277 Fontan procedures (44 atriopulmonary connections, 28 Fontan-Björk, 42 lateral tunnels and 163 extracardiac co... Abstract
Cited 19 times since 2019 (3.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 74, Issue 9, 1 1 2019, Pages 1177-1186 Effects of Alirocumab on Cardiovascular Events After Coronary Bypass Surgery. Goodman SG, Aylward PE, Szarek M, Chumburidze V, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Hanotin C, Harrington RA, Jukema JW, Kedev S, Letierce A, Moryusef A, Pordy R, Ramos López GA, Roe MT, Viigimaa M, White HD, Zeiher AM, Steg PG, Schwartz GG, ODYSSEY OUTCOMES Committees and Investigators
Background: Patients with acute coronary syndrome (ACS) and history of coronary artery bypass grafting (CABG) are at high risk for recurrent cardiovascular events and death. Objectives: This study sought to determine the clinical benefit of adding alirocumab to statins in ACS patients with prior CABG in a pre-specified analysis of ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab). Methods: Patients (n = 18,924) 1 to 12 mont... Abstract
Cited 10 times since 2019 (1.8 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 9, 1 1 2019, Pages 963-966 Criteria for surveys: from the European Association of Cardiovascular Imaging Scientific Initiatives Committee. Haugaa KH, Marsan NA, Cameli M, D'Andrea A, Dweck MR, Carvalho RF, Holte E, Manka R, Michalski B, Podlesnikar T, Popescu BA, Schulz-Menger J, Sitges M, Stankovic I, Maurer G, Edvardsen T
The European Association of Cardiovascular Imaging (EACVI) is committed to maintaining the highest standards of professional excellence in all aspects of cardiovascular imaging. The mission of the EACVI is to promote excellence in clinical diagnosis, research, technical development, and education in cardiovascular imaging with a particular focus on education, training, scientific initiatives, and research. The EACVI established the Scientific Initiatives Committee (SIC) in December 2018. This co... Abstract
Cited 27 times since 2019 (4.9 per year) source: EuropePMC
European heart journal, Volume 40, Issue 33, 1 1 2019, Pages 2801-2809 Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial. White HD, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Erglis A, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lopes RD, Mahaffey KW, Moryusef A, Pordy R, Roe MT, Sritara P, Tricoci P, Zeiher AM, Schwartz GG, ODYSSEY OUTCOMES Investigators
Aims: The third Universal Definition of Myocardial Infarction (MI) Task Force classified MIs into five types: Type 1, spontaneous; Type 2, related to oxygen supply/demand imbalance; Type 3, fatal without ascertainment of cardiac biomarkers; Type 4, related to percutaneous coronary intervention; and Type 5, related to coronary artery bypass surgery. Low-density lipoprotein cholesterol (LDL-C) reduction with statins and proprotein convertase subtilisin-kexin Type 9 (PCSK9) inhibitors reduces risk... Abstract
Cited 7 times since 2019 (1.3 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 42, Issue 10, 30 5 2019, Pages 1365-1373 Influence of risk factors in the ESC-EHRA EORP atrial fibrillation ablation long-term registry. Trines SA, Stabile G, Arbelo E, Dagres N, Brugada J, Kautzner J, Pokushalov E, Maggioni AP, Laroche C, Anselmino M, Beinart R, Traykov V, Blomström-Lundqvist C, ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry investigators
Background: The influence of risk factors on atrial fibrillation (AF) ablation recurrence is increasingly recognized. We present a sub-analysis of the European Society of Cardiology-European Heart Rhythm Association-European Society of Cardiology AF ablation long-term registry on the effect of traditional risk factors for AF on postablation recurrence, reablation, and complications using real-world data. Methods: Risk factors for AF were defined as body mass index ≥27 kg/m², hypertension, chroni... Abstract
Cited 4 times since 2019 (0.7 per year) source: EuropePMC
Journal of cardiovascular computed tomography, Volume 13, Issue 5, 30 5 2019, Pages 235-241 Noninvasive assessment of coronary atherosclerosis by cardiac computed tomography for risk stratifying patients with suspected coronary heart disease. van Rosendael AR, Bax JJ, Arbab-Zadeh A
Cited 87 times since 2019 (15.7 per year) source: EuropePMC
Biological psychiatry, Volume 87, Issue 5, 29 5 2019, Pages 409-418 Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, Pool R, Thesing CS, Vijfhuizen LS, Vogelzangs N, Arts ICW, Demirkan A, van Duijn C, van Greevenbroek M, van der Kallen CJH, Köhler S, Ligthart L, van den Maagdenberg AMJM, Mook-Kanamori DO, de Mutsert R, Tiemeier H, Schram MT, Stehouwer CDA, Terwindt GM, Willems van Dijk K, Fu J, Zhernakova A, Beekman M, Slagboom PE, Boomsma DI, Penninx BWJH, BBMRI-NL Metabolomics Consortium
Background: Depression has been associated with metabolic alterations, which adversely impact cardiometabolic health. Here, a comprehensive set of metabolic markers, predominantly lipids, was compared between depressed and nondepressed persons. Methods: Nine Dutch cohorts were included, comprising 10,145 control subjects and 5283 persons with depression, established with diagnostic interviews or questionnaires. A proton nuclear magnetic resonance metabolomics platform provided 230 metabolite mea... Abstract
Cited 3 times since 2019 (0.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 160, Issue 2, 28 4 2019, Pages 399-405 Clamping versus nonclamping thoracoscopic box ablation in long-standing persistent atrial fibrillation. Harlaar N, Verberkmoes NJ, van der Voort PH, Trines SA, Verstraeten SE, Mertens BJA, Klautz RJM, Braun J, van Brakel TJ
Objective: To compare clinical outcomes of clamping devices and linear nonclamping devices for isolation of the posterior left atrium (box) in thoracoscopic ablation of long-standing persistent atrial fibrillation. Methods: Eighty patients who underwent thoracoscopic pulmonary vein and box isolation using a bipolar clamping device (42 patients) or bipolar nonclamping device (38 patients) to create the roof/inferior lesions for box isolation were included from 2 centers. Follow-up consisted of 24... Abstract
Cited 10 times since 2019 (1.8 per year) source: EuropePMC
PLoS computational biology, Volume 15, Issue 8, 28 4 2019, Pages e1006697 Tracking Pseudomonas aeruginosa transmissions due to environmental contamination after discharge in ICUs using mathematical models. Pham TM, Kretzschmar M, Bertrand X, Bootsma M, COMBACTE-MAGNET Consortium
Pseudomonas aeruginosa (P. aeruginosa) is an important cause of healthcare-associated infections, particularly in immunocompromised patients. Understanding how this multi-drug resistant pathogen is transmitted within intensive care units (ICUs) is crucial for devising and evaluating successful control strategies. While it is known that moist environments serve as natural reservoirs for P. aeruginosa, there is little quantitative evidence regarding the contribution of environmental contamination... Abstract
Cited 5 times since 2019 (0.9 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 5, Issue 10, 28 4 2019, Pages 1115-1126 New Adjusted Cutoffs for "Normal" Endocardial Voltages in Patients With Post-Infarct LV Remodeling. Sramko M, Abdel-Kafi S, van der Geest RJ, de Riva M, Glashan CA, Lamb HJ, Zeppenfeld K
Objectives: This study sought to determine new reference cutoffs for normal unipolar voltage (UV) and bipolar voltage (BV) that would be adjusted for the LV remodeling. Background: The definition of "normal" left ventricular (LV) endocardial voltage in patients with post-infarct scar is still lacking. The reference voltage of the noninfarcted myocardium (NIM) may differ between patients depending on LV structural remodeling and the ensuing interstitial fibrosis. Methods: Electroanatomi... Abstract