7971 results
Cited 77 times since 2020 (16.3 per year)
source: EuropePMC
EMBO reports,
Volume 21, Issue 11, 7 1 2020, Pages e50636
Cell cycle dynamics of lamina-associated DNA.
van Schaik T, Vos M, Peric-Hupkes D, Hn Celie P, van Steensel B
In mammalian interphase nuclei, more than one thousand large genomic regions are positioned at the nuclear lamina (NL). These lamina-associated domains (LADs) are involved in gene regulation and may provide a backbone for the folding of interphase chromosomes. Little is known about the dynamics of LADs during interphase, in particular at the onset of G1 phase and during DNA replication. We developed an antibody-based variant of the DamID technology (named pA-DamID) that allows us to map and visu...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 71, 3 1 2020, Pages 411-418
Stent Graft Sizing for Endovascular Abdominal Aneurysm Repair Using Open Source Image Processing Software.
Knöps E, van Schaik J, van der Bogt KEA, Veger HTC, Putter H, Waasdorp EJ, van der Vorst JR
Introduction: An important step to reach a favorable outcome of abdominal endovascular aneurysm repair (EVAR) is preoperative sizing of the stent graft using computed tomography angiography (CTA) images of the abdominal aorta. A variety of costly image processing software options is available to obtain the necessary aortic measurements. A package that can be used for EVAR sizing is OsiriX Lite®-an open source, freely downloadable image processing option. This study assesses the concurrent validi...
Abstract
Cited 46 times since 2020 (9.7 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 22, Issue 9, 2 1 2020, Pages e20953
Telemonitoring for Patients With COVID-19: Recommendations for Design and Implementation.
Silven AV, Petrus AHJ, Villalobos-Quesada M, Dirikgil E, Oerlemans CR, Landstra CP, Boosman H, van Os HJA, Blanker MH, Treskes RW, Bonten TN, Chavannes NH, Atsma DE, Teng YKO
Despite significant efforts, the COVID-19 pandemic has put enormous pressure on health care systems around the world, threatening the quality of patient care. Telemonitoring offers the opportunity to carefully monitor patients with a confirmed or suspected case of COVID-19 from home and allows for the timely identification of worsening symptoms. Additionally, it may decrease the number of hospital visits and admissions, thereby reducing the use of scarce resources, optimizing health care capacit...
Abstract
Cited 5 times since 2020 (1.1 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 21, Issue 17, 2 1 2020, Pages E6364
Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning Methods.
Zhang H, Bredewold EOW, Vreeken D, Duijs JMGJ, de Boer HC, Kraaijeveld AO, Jukema JW, Pijls NH, Waltenberger J, Biessen EAL, van der Veer EP, van Zonneveld AJ, van Gils JM
Atherosclerosis is the underlying pathology in a major part of cardiovascular disease, the leading cause of mortality in developed countries. The infiltration of monocytes into the vessel walls of large arteries is a key denominator of atherogenesis, making monocytes accountable for the development of atherosclerosis. With the development of high-throughput transcriptome profiling platforms and cytometric methods for circulating cells, it is now feasible to study in-depth the predicted functiona...
Abstract
Cited 38 times since 2020 (8 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 34, 1 1 2020, Pages 3255-3268
Coexistence and outcome of coronary artery disease in Takotsubo syndrome.
Napp LC, Cammann VL, Jaguszewski M, Szawan KA, Wischnewsky M, Gili S, Knorr M, Heiner S, Citro R, Bossone E, D'Ascenzo F, Neuhaus M, Franke J, Sorici-Barb I, Noutsias M, Burgdorf C, Koenig W, Kherad B, Sarcon A, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Pott A, Meyer P, Arroja JD, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Hauck C, Paolini C, Bilato C, Imori Y, Kato K, Kobayashi Y, Opolski G, Budnik M, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Dichtl W, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, El-Battrawy I, Akin I, Gilyarova E, Shilova A, Gilyarov M, Horowitz JD, Polednikova K, Tousek P, Widimský P, Winchester DE, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Di Mario C, Prasad A, Rihal CS, Schulze PC, Bianco M, Crea F, Borggrefe M, Maier LS, Pinto FJ, Braun-Dullaeus RC, Rottbauer W, Katus HA, Hasenfuß G, Tschöpe C, Pieske BM, Thiele H, Schunkert H, Böhm M, Felix SB, Münzel T, Bax JJ, Bauersachs J, Braunwald E, Lüscher TF, R
Aims: Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a large cohort of patients with TTS. Methods and results: Coronary anatomy and CAD were s...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 2, 1 1 2020, Pages 649-651
Autonomic dysfunction in Huntington's disease: A <sup>123</sup>I-MIBG study.
Ng ACT, Delgado V, Bax JJ
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 9, 1 1 2020, Pages 959-960
An international, multicentre survey of echocardiographic abnormalities in COVID-19 patients.
Ng ACT, Delgado V, Bax JJ
Abstract
Cited 23 times since 2020 (4.8 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 9, 1 1 2020, Pages 973-980
Non-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study.
Ferraro RA, van Rosendael AR, Lu Y, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, de Araújo Gonçalves P, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Cho I, Danad I, Gransar H, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Berman DS, Chang HJ, Bax JJ, Min JK, Shaw LJ, Lin FY
Aims: High-risk plaque (HRP) and non-obstructive coronary artery disease independently predict adverse events, but their importance to future culprit lesions has not been resolved. We sought to determine in patients prior to confirmed acute coronary syndrome (ACS) the association between lesion percent diameter stenosis (%DS), and the absolute number and prevalence of HRP. The secondary objective was to examine the relative importance of non-obstructive HRP in future culprit lesions. Methods and...
Abstract
Cited 20 times since 2020 (4.2 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 33, 1 1 2020, Pages 3184-3197
Leaflet immobility and thrombosis in transcatheter aortic valve replacement.
Ng ACT, Holmes DR, Mack MJ, Delgado V, Makkar R, Blanke P, Leipsic JA, Leon MB, Bax JJ
Transcatheter aortic valve replacement (TAVR) has grown exponentially worldwide in the last decade. Due to the higher bleeding risks associated with oral anticoagulation and in patients undergoing TAVR, antiplatelet therapy is currently considered first-line antithrombotic treatment after TAVR. Recent studies suggest that some patients can develop subclinical transcatheter heart valve (THV) thrombosis after the procedure, whereby thrombus forms on the leaflets that can be a precursor to leaflet...
Abstract
Cited 133 times since 2020 (28 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 76, Issue 9, 1 1 2020, Pages 1018-1030
Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement.
Yoon SH, Kim WK, Dhoble A, Milhorini Pio S, Babaliaros V, Jilaihawi H, Pilgrim T, De Backer O, Bleiziffer S, Vincent F, Shmidt T, Butter C, Kamioka N, Eschenbach L, Renker M, Asami M, Lazkani M, Fujita B, Birs A, Barbanti M, Pershad A, Landes U, Oldemeyer B, Kitamura M, Oakley L, Ochiai T, Chakravarty T, Nakamura M, Ruile P, Deuschl F, Berman D, Modine T, Ensminger S, Kornowski R, Lange R, McCabe JM, Williams MR, Whisenant B, Delgado V, Windecker S, Van Belle E, Sondergaard L, Chevalier B, Mack M, Bax JJ, Leon MB, Makkar RR, Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry Investigators
Background: Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger populations will lead to increased use of TAVR for patients with bicuspid aortic valve (BAV) stenosis despite the exclusion of bicuspid anatomy in all pivotal clinical trials. Objectives: This study sought to evaluate the association of BAV morphology a...
Abstract
JACC. Clinical electrophysiology,
Volume 6, Issue 9, 1 1 2020, Pages 1191-1192
Reply: Debating the Definition and Incidence of Isolated Cardiac Sarcoidosis.
Hoogendoorn JC, Bogun FM, Tedrow UB, Stevenson WG, Zeppenfeld K
Abstract
Cited 10 times since 2020 (2.1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 22, Issue 9, 1 1 2020, Pages 1376-1383
The harm of delayed diagnosis of arrhythmogenic cardiac sarcoidosis: a case series.
Hoogendoorn JC, Ninaber MK, Piers SRD, de Riva M, Grauss RW, Bogun FM, Zeppenfeld K
Aims: Cardiac sarcoidosis (CS) is a known cause of ventricular tachycardia (VT). However, an arrhythmogenic presentation may not prompt immediate comprehensive evaluation. We aimed to assess the diagnostic and disease course of patients with arrhythmogenic cardiac sarcoidosis (ACS). Methods and results: From the Leiden VT-ablation-registry, consecutive patients with CS as underlying aetiology were retrospectively included. Data on clinical presentation, time-to-diagnosis, cardiac function, and c...
Abstract
Nature,
Volume 585, Issue 7825, 1 1 2020, Pages E11
Author Correction: Global status and conservation potential of reef sharks.
MacNeil MA, Chapman DD, Heupel M, Simpfendorfer CA, Heithaus M, Meekan M, Harvey E, Goetze J, Kiszka J, Bond ME, Currey-Randall LM, Speed CW, Sherman CS, Rees MJ, Udyawer V, Flowers KI, Clementi G, Valentin-Albanese J, Gorham T, Adam MS, Ali K, Pina-Amargós F, Angulo-Valdés JA, Asher J, Barcia LG, Beaufort O, Benjamin C, Bernard ATF, Berumen ML, Bierwagen S, Bonnema E, Bown RMK, Bradley D, Brooks E, Brown JJ, Buddo D, Burke P, Cáceres C, Cardeñosa D, Carrier JC, Caselle JE, Charloo V, Claverie T, Clua E, Cochran JEM, Cook N, Cramp J, D'Alberto B, de Graaf M, Dornhege M, Estep A, Fanovich L, Farabaugh NF, Fernando D, Flam AL, Floros C, Fourqurean V, Garla R, Gastrich K, George L, Graham R, Guttridge T, Hardenstine RS, Heck S, Henderson AC, Hertler H, Hueter R, Johnson M, Jupiter S, Kasana D, Kessel ST, Kiilu B, Kirata T, Kuguru B, Kyne F, Langlois T, Lédée EJI, Lindfield S, Luna-Acosta A, Maggs J, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Kaimuddin
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists,
Volume 39, Issue 5, 1 1 2020, Pages 420-427
Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer.
Kortekaas KE, Van de Vijver KK, van Poelgeest MIE, Gilks CB, Smit VTHBM, Arif S, Arora D, Faruqi A, Ganesan R, Griffin NR, Hale R, Hock YE, Horn LC, McCluggage WG, Mukonoweshuro P, Park KJ, Rous B, Tanchel B, Van Rompuy AS, van Schalkwyk G, Vella J, Vergine M, Singh N, Bosse T
Surgical resection with free surgical margins is the cornerstone of successful primary treatment of vulvar squamous cell carcinoma (VSCC). In general reexcision is recommended when the minimum peripheral surgical margin (MPSM) is
Abstract
JACC. Heart failure,
Volume 8, Issue 9, 1 1 2020, Pages 784-785
Reply: Assessment of Right Heart Function in Secondary Tricuspid Regurgitation.
Dietz MF, Prihadi EA, van der Bijl P, Ajmone Marsan N, Delgado V, Bax JJ
Abstract
Cited 16 times since 2020 (3.4 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 58, Issue 3, 1 1 2020, Pages 544-550
A structured approach to native mitral valve infective endocarditis: Is repair better than replacement?
Defauw RJ, Tomšič A, van Brakel TJ, Marsan NA, Klautz RJM, Palmen M
Objectives: Mitral valve repair in native active infective endocarditis is technically challenging. The survival benefit over valve replacement is poorly established and possibly absent because of the high risk of repair failure and reoperation. In this study, we explore the results of our structured approach in these patients. Methods: Between January 2000 and January 2017, 149 patients underwent surgery for native mitral infective endocarditis. Among them, 97 (66%) patients underwent valve rep...
Abstract
Cited 163 times since 2020 (34.3 per year)
source: EuropePMC
The New England journal of medicine,
Volume 383, Issue 15, 30 5 2020, Pages 1447-1457
Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.
Brouwer J, Nijenhuis VJ, Delewi R, Hermanides RS, Holvoet W, Dubois CLF, Frambach P, De Bruyne B, van Houwelingen GK, Van Der Heyden JAS, Toušek P, van der Kley F, Buysschaert I, Schotborgh CE, Ferdinande B, van der Harst P, Roosen J, Peper J, Thielen FWF, Veenstra L, Chan Pin Yin DRPP, Swaans MJ, Rensing BJWM, van 't Hof AWJ, Timmers L, Kelder JC, Stella PR, Baan J, Ten Berg JM
Background: The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been well studied. Methods: In a randomized, controlled trial, we assigned a subgroup of patients who were undergoing TAVI and did not have an indication for long-term anticoagulation, in a 1:1 ratio, to receive aspirin alone or aspirin plus clopidogr...
Abstract
Cited 951 times since 2020 (200.1 per year)
source: EuropePMC
The New England journal of medicine,
Volume 383, Issue 14, 29 5 2020, Pages 1305-1316
Early Rhythm-Control Therapy in Patients with Atrial Fibrillation.
Kirchhof P, Camm AJ, Goette A, Brandes A, Eckardt L, Elvan A, Fetsch T, van Gelder IC, Haase D, Haegeli LM, Hamann F, Heidbüchel H, Hindricks G, Kautzner J, Kuck KH, Mont L, Ng GA, Rekosz J, Schoen N, Schotten U, Suling A, Taggeselle J, Themistoclakis S, Vettorazzi E, Vardas P, Wegscheider K, Willems S, Crijns HJGM, Breithardt G, EAST-AFNET 4 Trial Investigators
Background: Despite improvements in the management of atrial fibrillation, patients with this condition remain at increased risk for cardiovascular complications. It is unclear whether early rhythm-control therapy can reduce this risk. Methods: In this international, investigator-initiated, parallel-group, open, blinded-outcome-assessment trial, we randomly assigned patients who had early atrial fibrillation (diagnosed ≤1 year before enrollment) and cardiovascular conditions to receive either ea...
Abstract
Cited 13 times since 2020 (2.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 135, 28 4 2020, Pages 84-90
Prognostic Implications of Significant Isolated Tricuspid Regurgitation in Patients With Atrial Fibrillation Without Left-Sided Heart Disease or Pulmonary Hypertension.
Dietz MF, Goedemans L, Vo NM, Prihadi EA, van der Bijl P, Gersh BJ, Ajmone Marsan N, Delgado V, Bax JJ
The prognostic impact of isolated tricuspid regurgitation (TR) in patients with atrial fibrillation (AF) has not been investigated. The purpose of this study was to investigate the prognostic implications of significant isolated TR in AF patients without left-sided heart disease, pulmonary hypertension, or primary structural abnormalities of the tricuspid valve. A total of 63 AF patients with moderate and severe TR were matched for age and gender to 116 AF patients without significant TR. Patien...
Abstract
Cited 40 times since 2020 (8.4 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 12, 26 4 2020, Pages 2576-2587
Sex Differences in Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve: Lessons From ADVANCE.
Fairbairn TA, Dobson R, Hurwitz-Koweek L, Matsuo H, Norgaard BL, Rønnow Sand NP, Nieman K, Bax JJ, Pontone G, Raff G, Chinnaiyan KM, Rabbat M, Amano T, Kawasaki T, Akasaka T, Kitabata H, Binukrishnan S, Rogers C, Berman D, Patel MR, Douglas PS, Leipsic J
Objectives: This study is to determine the management and clinical outcomes of patients investigated with coronary computed tomography angiography (CCTA)-derived fractional flow reserve (FFRCT) according to sex. Background: Women are underdiagnosed with conventional ischemia testing, have lower rates of obstructive coronary artery disease (CAD) at invasive coronary angiography (ICA), yet higher mortality compared to men. Whether FFRCT improves sex-based patient management decisions compared to C...
Abstract
