Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6136 results
Cited 21 times since 2015 (2.2 per year) source: EuropePMC
American heart journal, Volume 170, Issue 5, 4 1 2015, Pages 981-985.e1 Ticagrelor or prasugrel versus clopidogrel in elderly patients with an acute coronary syndrome: Optimization of antiplatelet treatment in patients 70 years and older--rationale and design of the POPular AGE study. Qaderdan K, Ishak M, Heestermans AA, de Vrey E, Jukema JW, Voskuil M, de Boer MJ, van't Hof AW, Groenemeijer BE, Vos GJ, Janssen PW, Bergmeijer TO, Kelder JC, Deneer VH, ten Berg JM
Rationale: Dual antiplatelet therapy with acetylsalicylic acid in combination with a more potent P2Y12- inhibitor (ticagrelor or prasugrel) is recommended in patients with acute coronary syndrome without ST-segment elevation (NSTE-ACS) to prevent atherothrombotic complications. The evidence on which this recommendation is based shows that ticagrelor and prasugrel reduce atherothrombotic events at the expense of an increase in bleeding events when compared with clopidogrel. However, it remains un... Abstract
Cited 24 times since 2015 (2.5 per year) source: EuropePMC
PloS one, Volume 10, Issue 8, 3 1 2015, Pages e0134245 Serum Cardiac Troponin-I is Superior to Troponin-T as a Marker for Left Ventricular Dysfunction in Clinically Stable Patients with End-Stage Renal Disease. Buiten MS, de Bie MK, Rotmans JI, Dekker FW, van Buren M, Rabelink TJ, Cobbaert CM, Schalij MJ, van der Laarse A, Jukema JW
Background: Serum troponin assays, widely used to detect acute cardiac ischemia, might be useful biomarkers to detect chronic cardiovascular disease (CVD). Cardiac-specific troponin-I (cTnI) and troponin-T (cTnT) generally detect myocardial necrosis equally well. In dialysis patients however, serum cTnT levels are often elevated, unlike cTnI levels. The present study aims to elucidate the associations of cTnI and cTnT with CVD in clinically stable dialysis patients. Methods: Troponin levels were... Abstract
Cited 19 times since 2015 (2 per year) source: EuropePMC
Circulation. Cardiovascular interventions, Volume 8, Issue 8, 1 1 2015, Pages e002740 Repeated Intramyocardial Bone Marrow Cell Injection in Previously Responding Patients With Refractory Angina Again Improves Myocardial Perfusion, Anginal Complaints, and Quality of Life. Mann I, Rodrigo SF, van Ramshorst J, Beeres SL, Dibbets-Schneider P, de Roos A, Wolterbeek R, Zwaginga JJ, Fibbe WE, Bax JJ, Schalij MJ, Atsma DE
Background: Intramyocardial bone marrow cell injection is associated with improvements in myocardial perfusion and anginal symptoms in patients with refractory angina pectoris. This study evaluates the effect of repeated intramyocardial bone marrow cell injection in patients with residual or recurrent myocardial ischemia. Methods and results: Twenty-three patients (17 men; 69±9 years) who had improved myocardial perfusion after the first injection but had residual or recurrent angina and ischemi... Abstract
Cited 4 times since 2015 (0.4 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 9, 1 1 2015, Pages 447-449 Heart failure in 2015: let's get organised! Lucas CM, van Pol PE, Eysink Smeets JB, Niesing M, Verwey HF, Beeres SL
Cited 10 times since 2015 (1 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 8, Issue 4, 1 1 2015, Pages 951-962 Twelve-lead ECG of ventricular tachycardia in structural heart disease. de Riva M, Watanabe M, Zeppenfeld K
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 9, 1 1 2015, Pages 453-454 Carotid sinus massage for diagnosis in narrow QRS tachycardia. Henkens IR, Zeppenfeld K, Hauer AD
Cited 37 times since 2015 (3.8 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 17 Suppl 4, 1 1 2015, Pages iv1-72 Current trends in the use of cardiac implantable electronic devices and interventional electrophysiological procedures in the European Society of Cardiology member countries: 2015 report from the European Heart Rhythm Association. Raatikainen MJ, Arnar DO, Zeppenfeld K, Merino JL, Kuck KH, Hindricks G
Aims: The aim was to provide comprehensive information on the use of cardiac implantable electronic device (CIED) and catheter ablation therapy in the European Society of Cardiology (ESC) area. Methods and results: The European Heart Rhythm Association (EHRA) has collected data on use of invasive arrhythmia managements since 2008. Fifty-one of the 56 ESC member countries provided data for the EHRA White Book 2015. This analysis is based on the current and previous editions of the EHRA White Book... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 23, Issue 9, 1 1 2015, Pages 450 Carotid sinus massage for diagnosis in narrow QRS tachycardia. Henkens IR, Zeppenfeld K, Hauer AD
Cited 14 times since 2015 (1.5 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 33, Issue 2, 1 1 2015, Pages 193-206 Reference Values for Echocardiography in Middle-Aged Population: The Cardiovascular Risk in Young Finns Study. Ruohonen S, Koskenvuo JW, Wendelin-Saarenhovi M, Savontaus M, Kähönen M, Laitinen T, Lehtimäki T, Jokinen E, Viikari J, Juonala M, Taittonen L, Tossavainen P, Kallio M, Bax JJ, Raitakari O
Background: Population and sex-specific reference limits produced with modern ultrasound equipment are needed for accurate clinical echocardiography diagnostics. We report a comprehensive set of reference limits of cardiac function and dimensions in a group of young and middle-aged Finnish men and women produced by the recommendations of European Society of Echocardiography and American Society of Cardiology. Methods and results: Cardiac structure and function was studied in a standardized compr... Abstract
Cited 4 times since 2015 (0.4 per year) source: EuropePMC
EBioMedicine, Volume 2, Issue 9, 31 5 2015, Pages 1217-1223 Continuous Postoperative Pericardial Flushing: A Pilot Study on Safety, Feasibility, and Effect on Blood Loss. Manshanden JS, Gielen CL, de Borgie CA, Klautz RJ, de Mol BA, Koolbergen DR
Background: Prolonged or excessive blood loss is a common complication after cardiac surgery. Blood remnants and clots, remaining in the pericardial space in spite of chest tube drainage, induce high fibrinolytic activity that may contribute to bleeding complications. Continuous postoperative pericardial flushing (CPPF) with an irrigation solution may reduce blood loss by preventing the accumulation of clots. In this pilot study, the safety and feasibility of CPPF were evaluated and the effect o... Abstract
Cited 45 times since 2015 (4.7 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 100, Issue 3, 28 4 2015, Pages 1126-1131 Reported Outcome After Valve-Sparing Aortic Root Replacement for Aortic Root Aneurysm: A Systematic Review and Meta-Analysis. Arabkhani B, Mookhoek A, Di Centa I, Lansac E, Bekkers JA, De Lind Van Wijngaarden R, Bogers AJ, Takkenberg JJ
Valve-sparing aortic root techniques have progressively gained ground in the treatment of aortic root aneurysm and aortic insufficiency. By avoiding anticoagulation therapy they offer a good alternative to composite graft replacement. This systematic review describes the reported outcome of valve-sparing aortic root replacement, focusing on the remodeling and reimplantation technique. A systematic literature search on the characteristics of and outcomes after valve-sparing aortic root replacemen... Abstract
Cited 4 times since 2015 (0.4 per year) source: EuropePMC
European heart journal, Volume 36, Issue 40, 28 4 2015, Pages 2681-2685 Research ethics needs fine tuning, not rigidity: how to promote evidence in neglected patient populations by rethinking informed consent. Jukema JW, Brouwer JR, Lüscher TF, Engberts DP, Quax PH
Cited 2 times since 2015 (0.2 per year) source: EuropePMC
Case reports in gastrointestinal medicine, Volume 2015, 22 4 2015, Pages 648417 A Rare Cause of Acute Abdomen: Perforation of Double Meckel's Diverticulum. Tas İ, Culcu S, Duzkoylu Y, Eryilmaz S, Deniz MM, Yilmaz D
Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. In this report, we aimed to represent a case of intestinal perforation, caused by double Meckel's diverticulum, which is a very rare entity in surgical practice. The patient was a 20-year-old Caucasian man, admitted to hospital with complaints of abdominal pain, nausea, and vomitting during the last 3 days. Physical examination indicated tenderness, rebound, and guarding in the right lower quadra... Abstract
European heart journal. Cardiovascular Imaging, Volume 17, Issue 6, 22 4 2015, Pages 652-659 Differential response of LV sublayer twist during dobutamine stress echocardiography as a novel marker of contractile reserve after acute myocardial infarction: relationship with follow-up LVEF improvement. Joyce E, Debonnaire P, Leong DP, Abate E, Katsanos S, Bax JJ, Delgado V, Ajmone Marsan N
Aims: Dobutamine stress echocardiography (DSE) is frequently performed to assess left ventricular (LV) contractile reserve in patients following myocardial infarction (STEMI). Given that resting LV sublayer twist assessment has been proposed as a marker of infarct transmurality, this study aimed to investigate whether response of LV subepicardial twist on DSE represents a novel quantitative marker of contractile reserve. Methods and results: First STEMI patients treated with primary percutaneous... Abstract
Cited 14 times since 2015 (1.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 150, Issue 5, 18 3 2015, Pages 1233-40.e1 Altered left ventricular vortex ring formation by 4-dimensional flow magnetic resonance imaging after repair of atrioventricular septal defects. Calkoen EE, Elbaz MS, Westenberg JJ, Kroft LJ, Hazekamp MG, Roest AA, van der Geest RJ
Objectives: During normal left ventricular (LV) filling, a vortex ring structure is formed distal to the left atrioventricular valve (LAVV). Vortex structures contribute to efficient flow organization. We aimed to investigate whether LAVV abnormality in patients with a corrected atrioventricular septal defect (AVSD) has an impact on vortex ring formation. Methods: Whole-heart 4D flow MRI was performed in 32 patients (age: 26 ± 12 years), and 30 healthy subjects (age: 25 ± 14 years). Vortex ring... Abstract
Cited 101 times since 2015 (10.5 per year) source: EuropePMC
Atherosclerosis, Volume 242, Issue 1, 17 3 2015, Pages 251-260 Valvular interstitial cells suppress calcification of valvular endothelial cells. Hjortnaes J, Shapero K, Goettsch C, Hutcheson JD, Keegan J, Kluin J, Mayer JE, Bischoff J, Aikawa E
Background: Calcific aortic valve disease (CAVD) is the most common heart valve disease in the Western world. We previously proposed that valvular endothelial cells (VECs) replenish injured adult valve leaflets via endothelial-to-mesenchymal transformation (EndMT); however, whether EndMT contributes to valvular calcification is unknown. We hypothesized that aortic VECs undergo osteogenic differentiation via an EndMT process that can be inhibited by valvular interstitial cells (VICs). Approach an... Abstract
Cited 8 times since 2015 (0.8 per year) source: EuropePMC
BMC cardiovascular disorders, Volume 15, 14 2 2015, Pages 68 Cathether-based interventional strategies for cor triatriatum in the adult - feasibility study through a hybrid approach. Li WW, Koolbergen DR, Bouma BJ, Hazekamp MG, de Mol BA, de Winter RJ
Background: Cor triatriatum is a rare congenital cardiac abnormality, consisting of an obstructing membrane between the pulmonary veins and the mitral valve in varying patterns. The entitiy can mimick the pathophysiology of mitral stenosis, necessitating surgical resection. Occasionally, percutaneous balloon dilatation of the membrane has been successfully performed. Case presentation: We report two cases with cor triatriatum where intraoperative balloon dilatation of the membrane was attempted... Abstract
Cited 9 times since 2015 (0.9 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 101, Issue 21, 14 2 2015, Pages 1717-1723 Individualised prediction of pulmonary homograft durability in tetralogy of Fallot. Bokma JP, Winter MM, Oosterhof T, Vliegen HW, van Dijk AP, Hazekamp MG, Koolbergen DR, Groenink M, Mulder BJ, Bouma BJ
Background: In patients with repaired tetralogy of Fallot (rTOF), multiple reoperations or percutaneous interventions after pulmonary valve replacement (PVR) may be necessary due to limited homograft durability. However, data to guide individualised prediction of homograft durability remain scarce. The aim of this study was to provide risk models for RV to pulmonary artery homograft durability. Methods: This retrospective multicentre study included consecutive patients with rTOF who had undergon... Abstract
Cited 30 times since 2015 (3.1 per year) source: EuropePMC
Neuroendocrinology, Volume 103, Issue 3-4, 14 2 2015, Pages 291-299 Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study. Blum MR, Wijsman LW, Virgini VS, Bauer DC, den Elzen WP, Jukema JW, Buckley BM, de Craen AJ, Kearney PM, Stott DJ, Gussekloo J, Westendorp RG, Mooijaart SP, Rodondi N, PROSPER study group
Background: Subclinical hypothyroidism has been associated with depressive symptoms in cross-sectional studies, but prospective data and data on subclinical hyperthyroidism are scarce. Methods: In the Leiden substudy of the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER), thyroid-stimulating hormone and free T4 levels were measured at baseline and repeated after 6 months in adults aged 70-82 years with preexisting cardiovascular disease or known cardiovascular risk factors to d... Abstract
Cited 19 times since 2015 (2 per year) source: EuropePMC
European heart journal, Volume 36, Issue 29, 13 2 2015, Pages 1851-1877 Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement: part 1: clinical trial design principles: A consensus document from the mitral valve academic research consortium. Stone GW, Vahanian AS, Adams DH, Abraham WT, Borer JS, Bax JJ, Schofer J, Cutlip DE, Krucoff MW, Blackstone EH, Généreux P, Mack MJ, Siegel RJ, Grayburn PA, Enriquez-Sarano M, Lancellotti P, Filippatos G, Kappetein AP, Mitral Valve Academic Research Consortium (MVARC)
Mitral regurgitation (MR) is one of the most prevalent valve disorders and has numerous aetiologies, including primary (organic) MR, due to underlying degenerative/structural mitral valve (MV) pathology, and secondary (functional) MR, which is principally caused by global or regional left ventricular remodelling and/or severe left atrial dilation. Diagnosis and optimal management of MR requires integration of valve disease and heart failure specialists, MV cardiac surgeons, interventional cardio... Abstract