Publications
Below you can find a list of our published research.
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Below you can find a list of our published research.
6205 results
Cited 3 times since 2014 (0.3 per year) source: EuropePMC
International journal of cardiology, Volume 172, Issue 1, 4 1 2014, Pages e3-5 Confounding factors in the relation between high sensitivity cardiac troponin T levels in serum and infarct size of patients with first ST-elevation myocardial infarction. Cobbaert CM, Bootsma M, Boden H, Ahmed TA, Hoogslag GE, Romijn FP, Ballieux BE, Wolterbeek R, Hermens WT, Schalij MJ, van der Laarse A
Cited 40 times since 2014 (3.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 22, Issue 1, 1 1 2014, Pages 3-10 Heart disease in the Netherlands: a quantitative update. Leening MJ, Siregar S, Vaartjes I, Bots ML, Versteegh MI, van Geuns RJ, Koolen JJ, Deckers JW
In this review we discuss cardiovascular mortality, incidence and prevalence of heart disease, and cardiac interventions and surgery in the Netherlands. We combined most recently available data from various Dutch cardiovascular registries, Dutch Hospital Data (LMR), Statistics Netherlands (CBS), and population-based cohort studies, to provide a broad quantitative update. The absolute number of people dying from cardiovascular diseases is declining and cardiovascular conditions are no longer the... Abstract
Cited 11 times since 2014 (1 per year) source: EuropePMC
Diabetes care, Volume 37, Issue 1, 1 1 2014, Pages e1-2 Very-low-calorie diet increases myocardial triglyceride content and decreases diastolic left ventricular function in type 2 diabetes with cardiac complications. Jonker JT, Djaberi R, van Schinkel LD, Hammer S, Bus MT, Kerpershoek G, Kharagjitsingh AV, Romijn JA, Bax JJ, Jukema JW, de Roos A, Smit JW, Lamb HJ
Cited 2 times since 2014 (0.2 per year) source: EuropePMC
Journal of cardiovascular pharmacology, Volume 63, Issue 1, 1 1 2014, Pages 16-22 Toll-like receptor 4 inhibitor TAK-242 treatment does not influence perfusion recovery in tissue ischemia. van den Borne P, Bastiaansen AJ, de Vries MR, Quax PH, Hoefer IE, Pasterkamp G
Toll-like receptors (TLRs) are important in innate immune responses, which are crucial in collateral artery formation (arteriogenesis). TLR4⁻/⁻ mice undergoing hind limb ischemia show decreased perfusion recovery accompanied by an impaired infiltration of inflammatory cells. TLR antagonists are currently developed and tested with the objective to inhibit acute exacerbation of organ damaging immune responses. However, systemic inhibition of innate immune responses may negatively influence arterio... Abstract
Cited 197 times since 2014 (17.3 per year) source: EuropePMC
JAMA, Volume 311, Issue 3, 1 1 2014, Pages 252-262 Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trial. Nicholls SJ, Kastelein JJ, Schwartz GG, Bash D, Rosenson RS, Cavender MA, Brennan DM, Koenig W, Jukema JW, Nambi V, Wright RS, Menon V, Lincoff AM, Nissen SE, VISTA-16 Investigators
Importance: Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor varespladib has favorable effects on lipid and inflammatory markers; however, its effect on cardiovascular outcomes is unknown. Objective: To determine the effects of sPLA2 inhibition with varespladib on cardiovascular outcomes. Design, setting, and participants: A double-blind, randomized, multicenter trial at 362 academic and community hospitals in Europe,... Abstract
Cited 39 times since 2014 (3.4 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 22, Issue 1, 1 1 2014, Pages 11-19 A review of the positive and negative effects of cardiovascular drugs on sexual function: a proposed table for use in clinical practice. Nicolai MP, Liem SS, Both S, Pelger RC, Putter H, Schalij MJ, Elzevier HW
Several antihypertensive drugs, such as diuretics and β-blockers, can negatively affect sexual function, leading to diminished quality of life and often to noncompliance with the therapy. Other drug classes, however, such as angiotensin II receptor blockers (ARBs) are able to improve patients' sexual function. Sufficient knowledge about the effects of these widely used antihypertensive drugs will make it possible for cardiologists and general practitioners to spare and even improve patients... Abstract
Cited 1 times since 2014 (0.1 per year) source: EuropePMC
Turk patoloji dergisi, Volume 30, Issue 2, 1 1 2014, Pages 118-123 A study on distribution of cancer cases diagnosed in Çorum. Baş Y, Uzbay P, Güney G, Erenler BH, Yilmaz D, Ozdemır C
Objective: In order to help obtain accurate knowledge and to contribute to the establishment of data for regional tumor statistics, we aimed to determine the frequency distribution of cancer cases that was diagnosed in Çorum province. Material and method: In this descriptive study, we retrospectively reviewed the archive records of the pathology departments' of one university hospital and two private hospitals serving in the province of Çorum. A total of 138,973 recorded pathology reports w... Abstract
Cited 26 times since 2014 (2.3 per year) source: EuropePMC
Acta cirurgica brasileira, Volume 29, Issue 1, 1 1 2014, Pages 59-65 Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs. Yilmaz D, Dogan N, Ozkan A, Sencimen M, Ora BE, Mutlu I
Purpose: To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. Methods: Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals were sacrificed on the 12th postoperative week and the tibial bones were removed, histologic sections we... Abstract
Bratislavske lekarske listy, Volume 115, Issue 7, 1 1 2014, Pages 400-404 Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitis. Comu FM, Ozturk L, Alkan M, Pampal K, Arslan M, Isik B, Atac MS, Yilmaz D
Purpose: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats. Materials and methods: Twenty- eight Wistar Albino rats were included in the study after streptozocin (60 mg/kg) treatment for 4 weeks of observation for diabetes presence. Twenty-eight rats were allocated to 4 groups. In group DP (n = 7) 150 mg.kg-1 of propofol was injected intraperitoneally. In group DP-vit C (n = 7) rats 100 mg/kg of vitamin C (Ascorbic aci... Abstract
Cited 34 times since 2013 (3 per year) source: EuropePMC
European heart journal, Volume 35, Issue 10, 29 5 2014, Pages 633-638 Risks and benefits of cardiac imaging: an analysis of risks related to imaging for coronary artery disease. Knuuti J, Bengel F, Bax JJ, Kaufmann PA, Le Guludec D, Perrone Filardi P, Marcassa C, Ajmone Marsan N, Achenbach S, Kitsiou A, Flotats A, Eeckhout E, Minn H, Hesse B
Cited 113 times since 2013 (9.9 per year) source: EuropePMC
Journal of virology, Volume 88, Issue 5, 26 4 2013, Pages 2844-2857 Genomewide analysis of reassortment and evolution of human influenza A(H3N2) viruses circulating between 1968 and 2011. Westgeest KB, Russell CA, Lin X, Spronken MI, Bestebroer TM, Bahl J, van Beek R, Skepner E, Halpin RA, de Jong JC, Rimmelzwaan GF, Osterhaus AD, Smith DJ, Wentworth DE, Fouchier RA, de Graaf M
Unlabelled: Influenza A(H3N2) viruses became widespread in humans during the 1968 H3N2 virus pandemic and have been a major cause of influenza epidemics ever since. These viruses evolve continuously by reassortment and genomic evolution. Antigenic drift is the cause for the need to update influenza vaccines frequently. Using two data sets that span the entire period of circulation of human influenza A(H3N2) viruses, it was shown that influenza A(H3N2) virus evolution can be mapped to 13 antigeni... Abstract
Cited 2 times since 2013 (0.2 per year) source: EuropePMC
The American journal of cardiology, Volume 113, Issue 6, 25 4 2013, Pages 982-987 Effect of cardiac resynchronization therapy on the sequence of mechanical activation assessed by two-dimensional radial strain imaging. Auger D, Hoke U, Thijssen J, Abate E, Yiu KH, Ewe SH, Witkowski TG, Leong DP, Holman ER, Ajmone Marsan N, Schalij MJ, Bax JJ, Delgado V
Cardiac resynchronization therapy (CRT) induces left ventricular (LV) reverse remodeling by synchronizing LV mechanical activation. We evaluated changes in segmental LV activation after CRT and related them to CRT response. A total of 292 patients with heart failure (65 ± 10 years, 77% men) treated with CRT underwent baseline echocardiographic assessment of LV volumes and ejection fraction. Time-to-peak radial strain was measured for 6 midventricular LV segments with speckle-tracking strain imag... Abstract
Cited 4 times since 2013 (0.3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 30, Issue 2, 19 3 2013, Pages 313-322 Left ventricular twist during dobutamine stress echocardiography after acute myocardial infarction: association with reverse remodeling. Joyce E, Leong DP, Hoogslag GE, van Herck PL, Debonnaire P, Abate E, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Left ventricular (LV) twist is emerging as a marker of global LV contractility after acute myocardial infarction (AMI). This study aimed to describe stress-induced changes in LV twist during dobutamine stress echocardiography (DSE) after AMI and investigate their association with LV reverse remodeling at 6 months follow-up. In 82 consecutive first AMI patients (61 ± 12 years, 85 % male) treated with primary percutaneous coronary intervention, DSE was performed at 3 months follow-up. Two-dimensio... Abstract
Cited 3 times since 2013 (0.3 per year) source: EuropePMC
Cardiovascular and interventional radiology, Volume 38, Issue 2, 19 3 2013, Pages 498-500 Endovascular salvage of a false aneurysm of the posterior tibial artery caused by a stab from a stingray. van Helden EJ, Eefting D, Florie J, Verhagen HJ, Moelker A
Cited 14 times since 2013 (1.2 per year) source: EuropePMC
JMIR research protocols, Volume 2, Issue 2, 17 3 2013, Pages e54 Evaluation of the Compliance, Acceptance, and Usability of a Web-Based eHealth Intervention for Parents of Children With Infantile Hemangiomas: Usability Study. de Graaf M, Totte J, Breugem C, van Os-Medendorp H, Pasmans S
Background: Infantile hemangiomas (IH) are common benign vascular tumors in children. Recognition and timely referral of high risk IH to specialized centers is important. This might be achieved by involving parents in the care for IH by means of an eHealth intervention. Objective: The objective of our study was to evaluate parent compliance, acceptance, and usability of an open access, Web-based eHealth intervention (including e-learning and e-consult) designed to increase parents' knowledg... Abstract
Cited 21 times since 2013 (1.8 per year) source: EuropePMC
Journal of medical genetics, Volume 51, Issue 2, 16 3 2013, Pages 122-131 A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K
Background: Osteoporosis is a systemic skeletal disease characterised by reduced bone mineral density and increased susceptibility to fracture; these traits are highly heritable. Both common and rare copy number variants (CNVs) potentially affect the function of genes and may influence disease risk. Aim: To identify CNVs associated with osteoporotic bone fracture risk. Method: We performed a genome-wide CNV association study in 5178 individuals from a prospective cohort in the Netherlands, inclu... Abstract
Cited 12 times since 2013 (1 per year) source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Volume 55, Issue 1, 12 2 2013, Pages 50-57 Additional diagnostic value of integrated analysis of cardiac CTA and SPECT MPI using the SMARTVis system in patients with suspected coronary artery disease. Kirişli HA, Gupta V, Shahzad R, Al Younis I, Dharampal A, Geuns RJ, Scholte AJ, de Graaf MA, Joemai RM, Nieman K, van Vliet L, van Walsum T, Lelieveldt B, Niessen WJ
Unlabelled: CT angiography (CTA) and SPECT myocardial perfusion imaging (MPI) are complementary imaging techniques to assess coronary artery disease (CAD). Spatial integration and combined visualization of SPECT MPI and CTA data may facilitate correlation of myocardial perfusion defects and subtending coronary arteries and thus offer additional diagnostic value over either stand-alone or side-by-side interpretation of the respective datasets from the 2 modalities. In this study, we investigated... Abstract
Cited 57 times since 2013 (5 per year) source: EuropePMC
International journal of cancer, Volume 134, Issue 11, 12 2 2013, Pages 2663-2673 Intraoperative fluorescence delineation of head and neck cancer with a fluorescent anti-epidermal growth factor receptor nanobody. van Driel PB, van der Vorst JR, Verbeek FP, Oliveira S, Snoeks TJ, Keereweer S, Chan B, Boonstra MC, Frangioni JV, van Bergen en Henegouwen PM, Vahrmeijer AL, Lowik CW
Intraoperative near-infrared (NIR) fluorescence imaging is a technology with high potential to provide the surgeon with real-time visualization of tumors during surgery. Our study explores the feasibility for clinical translation of an epidermal growth factor receptor (EGFR)-targeting nanobody for intraoperative imaging and resection of orthotopic tongue tumors and cervical lymph node metastases. The anti-EGFR nanobody 7D12 and the negative control nanobody R2 were conjugated to the NIR fluoroph... Abstract
Cited 4 times since 2013 (0.3 per year) source: EuropePMC
The American journal of cardiology, Volume 113, Issue 5, 12 2 2013, Pages 772-778 Prognostic value of aortic and mitral valve calcium detected by contrast cardiac computed tomography angiography in patients with suspicion of coronary artery disease. Kamperidis V, de Graaf MA, Broersen A, Ahmed W, Sianos G, Delgado V, Dijkstra J, Bax JJ, Scholte AJ
Aortic valve calcium (VC) detected on noncontrast cardiac computed tomography angiography (CCTA) is known to be associated with all-cause mortality in asymptomatic and primary prevention population. However, the clinical significance of aortic and mitral VC remains unknown in symptomatic patients with suspected coronary artery disease (CAD). The aim of the present study was to assess whether aortic and mitral VC is independently associated with cardiac events and all-cause mortality in symptomat... Abstract
Cited 6 times since 2013 (0.5 per year) source: EuropePMC
Urology, Volume 83, Issue 2, 9 2 2013, Pages 508.e7-12 The effect of intracavernosal avanafil, a newer phosphodiesterase-5 inhibitor, on neonatal type 2 diabetic rats with erectile dysfunction. Yilmaz D, Bayatli N, Un O, Kadowitz PJ, Sikka SC, Gur S
Objective: To determine the effect of avanafil, a novel phosphodiesterase-5 inhibitor, on the treatment of erectile dysfunction associated with type 2 diabetes mellitus (T2DM). Methods: In 2-day-old rats, T2DM was induced by single intraperitoneal injection of 90 mg/kg of streptozotocin (STZ; i.p.). Erectile responses were evaluated after 10 weeks on intracavernosal injection of avanafil (1 μM) to anesthetized rats and data expressed as intracavernosal pressure (ICP)/mean arterial pressure and t... Abstract