Research

Publications

Below you can find a list of our published research.

6173 results

Cited 60 times since 2003 (2.8 per year) source: EuropePMC

Archives of otolaryngology--head & neck surgery, Volume 129, Issue 11, 1 1 2003, Pages 1225-1229 Detection of Helicobacter pylori and its CagA gene in tonsil and adenoid tissues by PCR. Cirak MY, Ozdek A, Yilmaz D, Bayiz U, Samim E, Turet S

Objective: To determine the presence of Helicobacter pylori and, if detected, the prevalence of the CagA gene in adenotonsillectomy specimens by polymerase chain reaction (PCR). Design: A prospective clinical trial. Setting: Tertiary referral center. Patients and methods: The study population comprised 23 patients who had undergone adenoidectomy, tonsillectomy, or adenotonsillectomy under local or general anesthesia. Helicobacter pylori DNA was extracted from 3-mm-diameter tissue samples obtaine... Abstract

Cited 295 times since 2003 (13.7 per year) source: EuropePMC

The American journal of cardiology, Volume 92, Issue 10, 1 1 2003, Pages 1238-1240 Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation. Bax JJ, Marwick TH, Molhoek SG, Bleeker GB, van Erven L, Boersma E, Steendijk P, van der Wall EE, Schalij MJ

We evaluated patients with end-stage heart failure who have a high likelihood of response to cardiac resynchronization therapy (biventricular pacing). It appears that 20% of patients do not respond to this expensive therapy despite the use of selection criteria (dilated cardiomyopathy, heart failure, New York Heart Association class II or IV, left ventricular ejection fraction 120 ms). The presence of left ventricular dyssynchrony is needed to result in improvement after cardiac resynchronizatio... Abstract

Cited 13 times since 2003 (0.6 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 10, Issue 6, 1 1 2003, Pages 615-622 Risk stratification of patients after myocardial revascularization by stress Tc-99m tetrofosmin myocardial perfusion tomography. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Valkema R, Poldermans D

Background: The aim of this study was to assess the incremental prognostic value of stress technetium 99m tetrofosmin imaging after myocardial revascularization. Methods and results: We studied 381 patients (aged 60 +/- 10 years, 270 men), 4.5 +/- 3.2 years after myocardial revascularization (coronary artery bypass grafting in 201 patients and percutaneous coronary intervention in 180 patients), who underwent exercise or dobutamine stress tetrofosmin single photon emission computed tomography. E... Abstract

Cited 138 times since 2003 (6.4 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 42, Issue 10, 1 1 2003, Pages 1818-1825 Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT. Abidov A, Bax JJ, Hayes SW, Hachamovitch R, Cohen I, Gerlach J, Kang X, Friedman JD, Germano G, Berman DS

Objectives: This study evaluated the prognostic value of transient ischemic dilation (TID) of the left ventricle (LV) in patients with normal stress myocardial perfusion single photon emission computed tomography (MPS). Background: The prognostic value of TID in patients with an otherwise normal MPS has not been defined. Methods: We identified 1,560 patients who had normal stress MPS (436 vasodilator and 1,124 exercise stress), and no rest LV enlargement (Population 1) and followed up for 2.30 +... Abstract

Cited 47 times since 2003 (2.2 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 286, Issue 2, 9 2 2003, Pages H723-30 Quantification of left ventricular mechanical dyssynchrony by conductance catheter in heart failure patients. Steendijk P, Tulner SA, Schreuder JJ, Bax JJ, van Erven L, van der Wall EE, Dion RA, Schalij MJ, Baan J

Mechanical dyssynchrony is an important codeterminant of cardiac dysfunction in heart failure. Treatment, either medical, surgical, or by pacing, may improve cardiac function partly by improving mechanical synchrony. Consequently, the quantification of ventricular mechanical (dys)synchrony may have important diagnostic and prognostic value and may help to determine optimal therapy. Therefore, we introduced new indexes to quantify temporal and spatial aspects of mechanical dyssynchrony derived fr... Abstract

Cited 66 times since 2003 (3.1 per year) source: EuropePMC

Circulation, Volume 108, Issue 16, 6 1 2003, Pages 1954-1959 Impact of viability, ischemia, scar tissue, and revascularization on outcome after aborted sudden death. van der Burg AE, Bax JJ, Boersma E, Pauwels EK, van der Wall EE, Schalij MJ

Background: Survivors of aborted sudden death attributable to ventricular arrhythmias in the presence of coronary artery disease are at risk for recurrences. The substrate underlying these arrhythmias is not clear, and therefore the relation between ischemia, viability, scar tissue (and revascularization), and the incidence of ventricular arrhythmias (and survival) was studied over up to 3 years. Methods and results: One hundred fifty-three survivors of sudden death underwent stress-rest perfusi... Abstract

Cited 26 times since 2003 (1.2 per year) source: EuropePMC

Radiology, Volume 229, Issue 2, 2 1 2003, Pages 513-519 Real-time MR imaging of aortic flow: influence of breathing on left ventricular stroke volume in chronic obstructive pulmonary disease. van den Hout RJ, Lamb HJ, van den Aardweg JG, Schot R, Steendijk P, van der Wall EE, Bax JJ, de Roos A

Purpose: To assess real-time changes of left ventricular stroke volume (SV) in relation to the breathing pattern in healthy subjects and in patients with chronic obstructive pulmonary disease (COPD). Materials and methods: Real-time magnetic resonance (MR) imaging flow measurements were performed in the ascending aorta of 10 healthy volunteers and nine patients with severe COPD. Breathing maneuvers were registered with an abdominal pressure belt, which was synchronized to the electrocardiographi... Abstract

Cited 29 times since 2003 (1.3 per year) source: EuropePMC

Archives of internal medicine, Volume 163, Issue 18, 1 1 2003, Pages 2230-2235 Optimizing long-term cardiac management after major vascular surgery: Role of beta-blocker therapy, clinical characteristics, and dobutamine stress echocardiography to optimize long-term cardiac management after major vascular surgery. Kertai MD, Boersma E, Bax JJ, Thomson IR, Cramer MJ, van de Ven LL, Scheffer MG, Trocino G, Vigna C, Baars HF, van Urk H, Roelandt JR, Poldermans D, Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography (DECREASE) Study Group

Background: Survivors of major vascular surgery are at increased risk of late cardiac complications. Objective: To examine the cardioprotective effect of beta-blockers. Methods: A follow-up study was conducted in 1286 patients who survived surgery for at least 30 days. Patients were screened for cardiac risk factors and dobutamine stress echocardiography (DSE) results; 1034 patients (80%) underwent preoperative DSE, and 370 (29%) received beta-blockers. The main outcome measure was late cardiac... Abstract

Cited 16 times since 2003 (0.7 per year) source: EuropePMC

Journal of hypertension, Volume 21, Issue 10, 1 1 2003, Pages 1945-1951 Prediction of cardiac death in hypertensive patients with suspected or known coronary artery disease by stress technetium-99m tetrofosmin myocardial perfusion imaging. Elhendy A, Schinkel AF, Van Domburg RT, Bax JJ, Poldermans D

Background: There are currently insufficient data to indicate a role for stress myocardial perfusion imaging as a prognostic tool in hypertensive patients. Objectives: To assess the incremental value of stress myocardial perfusion imaging for the prediction of cardiac death in hypertensive patients relative to clinical data. Patients: We studied 601 hypertensive patients (aged 59 +/- 10 years, 387 men) who underwent exercise bicycle or dobutamine (up to 40 microg/kg per min) stress technetium-99... Abstract

Cited 19 times since 2003 (0.9 per year) source: EuropePMC

Anesthesia and analgesia, Volume 97, Issue 4, 1 1 2003, Pages 950-957 Perioperative assessment of left ventricular function by pressure-volume loops using the conductance catheter method. Tulner SAF, Klautz RJM, van Rijk-Zwikker GL, Engbers FHM, Bax JJ, Baan J, van der Wall EE, Dion RA, Steendijk P

Unlabelled: Interpretation of perioperative measurements of cardiac function during cardiac surgery is complicated by changes in loading conditions induced by anesthesia, cardiopulmonary bypass (CPB), and the surgical procedure itself. Quantification of left ventricular (LV) function by pressure-volume relations as obtained by the conductance catheter would be advantageous because load-independent indices can be determined. Accordingly, we evaluated methodological aspects of the conductance-cath... Abstract

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 11, Issue 10, 1 1 2003, Pages 416-417 Noncompaction cardiomyopathy. Jongbloed MR, Bax JJ, Schalij MJ, van der Wall EE

Abstract

Cited 61 times since 2003 (2.8 per year) source: Scopus

Reproduction (Cambridge, England), Volume 126, Issue 4, 1 1 2003, Pages 469-480 Proliferation and apoptosis in bovine placentomes during pregnancy and around induced and spontaneous parturition as well as in cows retaining the fetal membranes. Boos A, Janssen V, Mülling C

Placental growth can be achieved by either cellular proliferation or hypertrophy. Tissue regeneration and the nutrition of the fetus via embryotrophe require high rates of cellular turnover and the so-called pre-term 'maturation' of the placenta is correlated with a reduction of maternal crypt epithelial cells. Placentomes of 45 pregnant cows were collected from an abattoir to assess the role of proliferation and apoptosis in placental physiology and pathology. Placentomes were also ta... Abstract

Cited 1 times since 2003 (0 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 19, Issue 5, 1 1 2003, Pages 367-369 Congenital coronary artery anomalies angiographic classification revisited. Vliegen HW, Bruschke AV

Abstract

Cited 83 times since 2003 (3.8 per year) source: EuropePMC

Journal of cell science, Volume 116, Issue Pt 19, 1 1 2003, Pages 3971-3984 Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. Ritzi M, Tillack K, Gerhardt J, Ott E, Humme S, Kremmer E, Hammerschmidt W, Schepers A

The sequential binding of the origin recognition complex (ORC), Cdc6p and the minichromosome maintenance proteins (MCM2-7) mediates replication competence at eukaryotic origins of DNA replication. The latent origin of Epstein-Barr virus, oriP, is a viral origin known to recruit ORC. OriP also binds EBNA1, a virally encoded protein that lacks any activity predicted to be required for replication initiation. Here, we used chromatin immunoprecipitation and chromatin binding to compare the cell-cycl... Abstract

Cited 21 times since 2003 (1 per year) source: EuropePMC

Pacing and clinical electrophysiology : PACE, Volume 26, Issue 10, 1 1 2003, Pages 2042-2044 Resynchronization therapy after congenital heart surgery to improve left ventricular function. Roofthooft MT, Blom NA, Rijlaarsdam ME, Bökenkamp R, Ottenkamp J, Schalij MJ, Bax JJ, Hazekamp MG

This report describes the mid-term beneficial hemodynamic effect of biventricular pacing in an infant with congestive heart failure after congenital heart surgery, due to resynchronization of the left and right ventricle, optimization of the AV delay, and (partial) correction of the LV dyssynchrony. Abstract

Cited 19 times since 2003 (0.9 per year) source: EuropePMC

Journal of cardiovascular electrophysiology, Volume 14, Issue 10, 1 1 2003, Pages 1110-1112 Transvenous biventricular pacing in a child after congenital heart surgery as an alternative therapy for congestive heart failure. Blom NA, Bax JJ, Ottenkamp J, Schalij MJ

Transvenous Biventricular Pacing in Children. Cardiac resynchronization therapy improves short-term and long-term hemodynamics in adult patients with congestive heart failure and left bundle branch block. We describe the feasibility of transvenous biventricular pacemaker implantation in a 6-year-old child with heart failure and wide QRS complex after congenital heart surgery. Myocardial tissue Doppler imaging was used to demonstrate intraventricular dyssynchrony and resynchronization after cardi... Abstract

Cited 32 times since 2003 (1.5 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 126, Issue 4, 1 1 2003, Pages 1053-1060 Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation. Lalezari S, Hazekamp MG, Bartelings MM, Schoof PH, Gittenberger-De Groot AC

Objective: Transposition of the great arteries is currently treated by performing the arterial switch operation. Dilatation of the neoaortic root is a late complication with unknown cause. Samples of patients with untreated transposition of the great arteries and patients with normally related great arteries were compared to investigate a possible role for vascular remodeling in the dilatation process. Methods: Aortic and pulmonary artery vessel wall and sinus samples were taken from 20 untreate... Abstract

Cited 61 times since 2003 (2.8 per year) source: EuropePMC

Circulation, Volume 108, Issue 17, 29 5 2003, Pages 2099-2106 Voltage and activation mapping: how the recording technique affects the outcome of catheter ablation procedures in patients with congenital heart disease. de Groot NM, Schalij MJ, Zeppenfeld K, Blom NA, Van der Velde ET, Van der Wall EE

Background: Endocardial mapping is mandatory before radiofrequency catheter ablation (RFCA). Mapping can be performed with either unipolar or bipolar recordings. Impact of the recording technique used was studied in patients with and without structural heart disease using the 3D electroanatomic CARTO mapping system. Methods and results: Patients (n=44; 16 males; age 43+/-16 years) referred for RFCA of atrial flutter (AFL, n=18), focal atrial tachycardia (FAT, n=4), AV nodal reentrant tachycardia... Abstract

Cited 4 times since 2003 (0.2 per year) source: EuropePMC

Radiology, Volume 228, Issue 3, 1 1 2003, Pages 834-841 Vein graft function improvement after percutaneous intervention: evaluation with MR flow mapping. Langerak SE, Vliegen HW, Jukema JW, Zwinderman AH, Lamb HJ, de Roos A, van der Wall EE

Purpose: To provide functional reference values in single and sequential vein grafts by using magnetic resonance (MR) flow mapping and to examine the effect of percutaneous intervention (PCI) on coronary artery bypass graft function. Materials and methods: Fast MR flow mapping at baseline and during adenosine-induced stress was performed in 39 nonstenotic single vein grafts and 20 nonstenotic sequential vein grafts, as well as in 15 stenotic vein grafts before and 7.3 weeks +/- 1.5 after success... Abstract

Cited 38 times since 2003 (1.8 per year) source: EuropePMC

Circulation, Volume 108 Suppl 1, 1 1 2003, Pages II39-42 Early versus delayed revascularization in patients with ischemic cardiomyopathy and substantial viability: impact on outcome. Bax JJ, Schinkel AF, Boersma E, Rizzello V, Elhendy A, Maat A, Roelandt JR, van der Wall EE, Poldermans D

Background: Patients with ischemic cardiomyopathy and viable myocardium may improve in function and prognosis following revascularization. Delayed revascularization may result in less favorable outcome, and therefore the impact of timing of revascularization on long-term outcome was evaluated. Methods and results: Patients (n=85) with ischemic cardiomyopathy and substantial viability (>or=25% of the left ventricle) on dobutamine stress echocardiography underwent surgical revascularization. Ba... Abstract