Research

Publications

Below you can find a list of our published research.

6128 results

Cited 3 times since 2007 (0.2 per year) source: EuropePMC

Current opinion in anaesthesiology, Volume 20, Issue 3, 1 1 2007, Pages 254-260 Perioperative medical management of ischemic heart disease in patients undergoing noncardiac surgery. Feringa HH, Bax JJ, Poldermans D

Purpose of review: Cardiovascular disease is the leading cause of death after anesthesia and surgery. The preoperative identification of patients with underlying coronary artery disease is important to initiate appropriate treatment strategies in order to reduce the risk of perioperative complications. The current review will discuss new insights in the field of perioperative medicine that can be applied to clinical practice or stimulate further investigation. Recent findings: Recent findings in... Abstract

Cited 12 times since 2007 (0.7 per year) source: EuropePMC

Current opinion in anaesthesiology, Volume 20, Issue 3, 1 1 2007, Pages 274-278 Management of patients with cardiac stents undergoing noncardiac surgery. Schouten O, Bax JJ, Poldermans D

Purpose of review: Coronary stenting is performed in over 4 million patients annually. Approximately 5% of these patients undergo a noncardiac surgical procedure within 1 year after stenting. Surgery might induce hypercoagulability. This causes increased concern about the effects of previous coronary stenting on postoperative cardiac outcome, particularly in-stent thrombosis. On the other hand, patients with multiple cardiac risk factors are at high risk for postoperative adverse cardiac events... Abstract

Cited 37 times since 2007 (2.1 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 94, Issue 1, 31 5 2007, Pages 48-52 Gender influence on the diagnostic accuracy of 64-slice multislice computed tomography coronary angiography for detection of obstructive coronary artery disease. Pundziute G, Schuijf JD, Jukema JW, van Werkhoven JM, Boersma E, de Roos A, van der Wall EE, Bax JJ

Objective: To compare the diagnostic accuracy of 64-slice multislice computed tomography (MSCT) coronary angiography between female and male patients using conventional coronary angiography as the reference standard. Design: Diagnostic accuracy study. Setting: University hospital. Patients: 103 consecutive patients (51 men, 52 women, mean (SD) age 60 (10) years) with known and suspected coronary artery disease underwent 64-slice MSCT. Main outcome measures: Diagnostic accuracy of 64-slice MSCT t... Abstract

Cited 11 times since 2007 (0.6 per year) source: EuropePMC

Heart rhythm, Volume 4, Issue 9, 24 4 2007, Pages 1144-1148 Does left ventricular dyssynchrony immediately after acute myocardial infarction result in left ventricular dilatation? Mollema SA, Bleeker GB, Liem SS, Boersma E, van der Hoeven BL, Holman ER, van der Wall EE, Schalij MJ, Bax JJ

Background: Reverse remodeling of the left ventricle (LV) is one of the advantageous mechanisms of cardiac resynchronization therapy (CRT). Substantial LV dyssynchrony seems mandatory for echocardiographic response to CRT. Conversely, LV dyssynchrony early after acute myocardial infarction may result in LV dilatation during follow-up. Objective: The purpose of this study was to evaluate the relation between LV dyssynchrony early after acute myocardial infarction and the occurrence of long-term L... Abstract

Cited 66 times since 2007 (3.7 per year) source: EuropePMC

Journal of lipid research, Volume 48, Issue 8, 24 4 2007, Pages 1763-1771 Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression. van der Hoogt CC, de Haan W, Westerterp M, Hoekstra M, Dallinga-Thie GM, Romijn JA, Princen HM, Jukema JW, Havekes LM, Rensen PC

In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol is dependent on the expression of the cholesteryl ester transfer protein (CETP). To this end, APOE*3-Leiden (E3L) transgenic mice without and with the human CETP transgene, under the control of its natural regulatory flanking regions, were fed a Western-type diet with or without fenofibrate. Fenofibrate... Abstract

Cited 76 times since 2007 (4.3 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 49, Issue 22, 23 4 2007, Pages 2204-2210 Usefulness of 64-slice multislice computed tomography coronary angiography to assess in-stent restenosis. Cademartiri F, Schuijf JD, Pugliese F, Mollet NR, Jukema JW, Maffei E, Kroft LJ, Palumbo A, Ardissino D, Serruys PW, Krestin GP, Van der Wall EE, de Feyter PJ, Bax JJ

Objectives: This study sought to evaluate the diagnostic accuracy of 64-slice multislice computed tomography (MSCT) coronary angiography in the follow-up of patients with previous coronary stent implantation. Background: Recent investigations have shown increased image quality and diagnostic accuracy for noninvasive coronary angiography with 64-slice MSCT as compared with previous-generation MSCT scanners, but data on the evaluation of coronary stents are scarce. Methods: In 182 patients (152 [8... Abstract

Cited 65 times since 2007 (3.7 per year) source: EuropePMC

The American journal of cardiology, Volume 100, Issue 2, 22 4 2007, Pages 316-320 Effect of statin withdrawal on frequency of cardiac events after vascular surgery. Schouten O, Hoeks SE, Welten GM, Davignon J, Kastelein JJ, Vidakovic R, Feringa HH, Dunkelgrun M, van Domburg RT, Bax JJ, Poldermans D

The discontinuation of statin therapy in patients with acute coronary syndromes has been associated with an increase of adverse coronary events. Patients who undergo major surgery frequently are not able to take oral medication shortly after surgery. Because there is no intravenous formula for statins, the interruption of statins in the postoperative period is a serious concern. The objective of this study was to assess the effect of perioperative statin withdrawal on postoperative cardiac outco... Abstract

Cited 71 times since 2007 (4 per year) source: EuropePMC

Clinical and vaccine immunology : CVI, Volume 14, Issue 7, 16 3 2007, Pages 880-885 Discrepancy between Mycobacterium tuberculosis-specific gamma interferon release assays using short and prolonged in vitro incubation. Leyten EM, Arend SM, Prins C, Cobelens FG, Ottenhoff TH, van Dissel JT

The sensitivities of various gamma interferon release assays (IGRAs) for the detection of past latent Mycobacterium tuberculosis infection are not known. In this study, we aimed to assess the effects of various IGRA formats and in vitro incubation periods on test outcome. The results of the tuberculin skin test (TST) were compared with those of the QuantiFERON-TB Gold in-tube (QFT-GIT) test, an overnight enzyme-linked immunospot assay (ELISPOT), and a 6-day lymphocyte stimulation test (LST) by u... Abstract

Cited 29 times since 2007 (1.6 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 293, Issue 2, 11 2 2007, Pages H1300-7 Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography. Henkens IR, Mouchaers KT, Vliegen HW, van der Laarse WJ, Swenne CA, Maan AC, Draisma HH, Schalij I, van der Wall EE, Schalij MJ, Vonk-Noordegraaf A

The study aim was to assess three-dimensional electrocardiogram (ECG) changes during development of pulmonary arterial hypertension (PAH). PAH was induced in male Wistar rats (n = 23) using monocrotaline (MCT; 40 mg/kg sc). Untreated healthy rats served as controls (n = 5). ECGs were recorded with an orthogonal three-lead system on days 0, 14, and 25 and analyzed with dedicated computer software. In addition, left ventricular (LV)-to-right ventricular (RV) fractional shortening ratio was determi... Abstract

Cited 7 times since 2007 (0.4 per year) source: EuropePMC

Genomics, Volume 90, Issue 1, 11 2 2007, Pages 110-120 Gene identification and evidence for expression of G protein alpha subunits, phospholipase C, and an inositol 1,4,5-trisphosphate receptor in Aplysia californica rhinophore. Cummins SF, De Vries MR, Hill KS, Boehning D, Nagle GT

In the marine mollusk Aplysia californica, waterborne protein pheromones that are released during egg laying act in concert to stimulate mate attraction. However, molecular information concerning the cellular receptors and signaling mechanisms that may be involved in waterborne peptide and protein pheromonal communication is lacking. As a first step toward examining whether members of the G protein family and phosphoinositide signaling pathway are present in the primary peripheral chemosensory o... Abstract

Cited 62 times since 2007 (3.5 per year) source: EuropePMC

International journal of cardiology, Volume 126, Issue 2, 4 1 2007, Pages 240-246 Risk of complications during pregnancy in women with congenital aortic stenosis. Yap SC, Drenthen W, Pieper PG, Moons P, Mulder BJ, Mostert B, Vliegen HW, van Dijk AP, Meijboom FJ, Steegers EA, Roos-Hesselink JW, ZAHARA investigators

Background: Pregnancy in women with congenital aortic stenosis (AS) is associated with increased cardiac complications. Data on non-cardiac complications are limited, and this information is crucial for prenatal counselling and perinatal care. The aim of this study was to present the maternal and perinatal outcome of pregnancy in women with congenital AS. Methods: By review of the Dutch CONCOR national registry and a local Belgian tertiary care centre database, 35 women with congenital AS with a... Abstract

Cited 19 times since 2007 (1.1 per year) source: EuropePMC

Journal of the American Society of Nephrology : JASN, Volume 18, Issue 6, 2 1 2007, Pages 1872-1879 Lower progression rate of end-stage renal disease in patients with peripheral arterial disease using statins or Angiotensin-converting enzyme inhibitors. Feringa HH, Karagiannis SE, Chonchol M, Vidakovic R, Noordzij PG, Elhendy A, van Domburg RT, Welten G, Schouten O, Bax JJ, Berl T, Poldermans D

Patients with peripheral arterial disease (PAD) are at increased risk for ESRD and cardiovascular events. The primary objective was to assess the association between ankle-brachial index (ABI) values and renal outcome. The secondary objective was to evaluate whether statins and angiotensin-converting enzyme inhibitors (ACEI) are associated with improved renal and cardiovascular outcome in patients with PAD. In a prospective observational cohort study of 1940 consecutive patients with PAD, ABI wa... Abstract

Cited 95 times since 2007 (5.3 per year) source: EuropePMC

Annals of internal medicine, Volume 146, Issue 9, 1 1 2007, Pages 640-648 Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk. van der Steeg WA, Boekholdt SM, Stein EA, El-Harchaoui K, Stroes ES, Sandhu MS, Wareham NJ, Jukema JW, Luben R, Zwinderman AH, Kastelein JJ, Khaw KT

Background: An elevated apolipoprotein B-apolipoprotein A-I (apo B-apo A-I) ratio is a risk factor for future coronary artery disease (CAD). It is not known whether this ratio is better than traditional lipid values for risk assessment and prediction and whether it adds predictive value to the Framingham risk score. Objective: To evaluate whether the apo B-apo A-I ratio is associated with future CAD events independent of traditional lipid measurements and the Framingham risk score and to evaluat... Abstract

Cited 65 times since 2007 (3.6 per year) source: EuropePMC

Journal of cardiac failure, Volume 13, Issue 4, 1 1 2007, Pages 294-303 Effect of exercise training on autonomic derangement and neurohumoral activation in chronic heart failure. Gademan MG, Swenne CA, Verwey HF, van der Laarse A, Maan AC, van de Vooren H, van Pelt J, van Exel HJ, Lucas CM, Cleuren GV, Somer S, Schalij MJ, van der Wall EE

Background: In chronic heart failure (CHF), persistent autonomic derangement and neurohumoral activation cause structural end-organ damage, decrease exercise capacity, and reduce quality of life. Beneficial effects of pharmacotherapy and of exercise training in CHF have been documented at various functional and structural levels. However, pharmacologic treatment can not yet reduce autonomic derangement and neurohumoral activation in CHF to a minimum. Various studies suggest that exercise trainin... Abstract

Cited 99 times since 2007 (5.5 per year) source: EuropePMC

Diabetes, obesity & metabolism, Volume 9, Issue 3, 1 1 2007, Pages 218-232 Cardiovascular metabolic syndrome - an interplay of, obesity, inflammation, diabetes and coronary heart disease. Rana JS, Nieuwdorp M, Jukema JW, Kastelein JJ

Cardiovascular disease is currently one of the biggest causes of morbidity and mortality facing humanity. Such a paradigm shift of disease pattern over the last century has only worsened due to the alarming global prevalence of obesity and type 2 diabetes. In recent years there is increasing focus on inflammation as one of the key players in the patho-physiology of these disorders. In addition to these overt risk factors new research is unraveling the significance of a constellation of early met... Abstract

Cited 9 times since 2007 (0.5 per year) source: EuropePMC

Anesthesiology, Volume 106, Issue 5, 1 1 2007, Pages 1067-1069 Coronary artery stent placement immediately before noncardiac surgery: a potential risk? Schouten O, Bax JJ, Damen J, Poldermans D

Abstract

Cited 5 times since 2007 (0.3 per year) source: EuropePMC

Coronary artery disease, Volume 18, Issue 3, 1 1 2007, Pages 187-192 The long prognostic value of wall motion abnormalities during the recovery phase of dobutamine stress echocardiography after receiving acute beta-blockade. Karagiannis SE, Elhendy A, Feringa HH, van Domburg R, Bax JJ, Vidakovic R, Cokkinos DV, Poldermans D

Objective: To assess the prognostic value of wall motion abnormalities during the recovery phase of dobutamine stress echocardiography in addition to wall motion abnormalities at peak stress. Methods: Wall motion abnormalities were assessed at peak and during recovery phase of dobutamine stress echocardiography in 187 consecutive patients, who were followed for occurrence of cardiac events. Results: During follow-up (mean 36+/-28 months), 19 patients (10%) died from cardiac causes, 34 (18%) pati... Abstract

Cited 3 times since 2007 (0.2 per year) source: EuropePMC

The American journal of medicine, Volume 120, Issue 6, 26 4 2007, Pages 531-538 Improving risk assessment with cardiac testing in peripheral arterial disease. Feringa HH, Elhendy A, Karagiannis SE, Noordzij PG, Dunkelgrun M, Schouten O, Vidakovic R, van Domburg RT, Bax JJ, Poldermans D

Purpose: The study's objective was to evaluate the prognostic value of left ventricular ejection fraction and stress-induced ischemia during dobutamine stress echocardiography, in addition to ankle-brachial index measurements and clinical risk factors in patients with suspected or known peripheral arterial disease. Methods: In 852 patients with suspected or known peripheral arterial disease (mean age 63 years, 70% male), the ankle-brachial index was measured, left ventricular ejection fract... Abstract

Cited 6 times since 2007 (0.3 per year) source: EuropePMC

International journal of cardiology, Volume 125, Issue 3, 26 4 2007, Pages 358-363 Significance of hypotensive response during dobutamine stress echocardiography. Dunkelgrun M, Hoeks SE, Elhendy A, van Domburg RT, Bax JJ, Noordzij PG, Feringa HH, Vidakovic R, Karagiannis SE, Schouten O, Poldermans D

Background: In patients undergoing exercise testing a hypotensive response is associated with a poor prognosis. There is limited information regarding the prognostic significance of hypotension during dobutamine stress test. This study investigates the association between a severe hypotensive response during DSE and long-term prognosis. Methods: Patients (3381) underwent dobutamine stress echocardiography (DSE). Blood pressure was measured automatically at rest and at the end of every dose-step.... Abstract

Cited 8 times since 2007 (0.4 per year) source: EuropePMC

European heart journal, Volume 28, Issue 10, 25 4 2007, Pages 1182-1183 Importance of left ventricular lead position in cardiac resynchronization therapy. Bleeker GB, Schalij MJ, Bax JJ

Abstract