Research

Publications

Below you can find a list of our published research.

8684 results

Cited 10 times since 2013 (0.9 per year) source: EuropePMC

American heart journal, Volume 167, Issue 2, 6 1 2013, Pages 178-185 Erectile dysfunction in the cardiology practice-a patients' perspective. Nicolai MP, van Bavel J, Somsen GA, de Grooth GJ, Tulevski II, Lorsheyd A, Putter H, Schalij MJ, Pelger RC, Elzevier HW

Background: Erectile dysfunction (ED) is an independent risk factor for cardiovascular events sharing mutual risk factors with coronary artery disease. Several guidelines for the management of ED in cardiovascular disease have been proposed, recommending cardiologists to routinely inquire about erectile function. However, males' specific needs and wishes regarding sexual health care in cardiology are unknown. We sought to identify male patients' view concerning possible improvements in... Abstract

Cited 12 times since 2013 (1 per year) source: EuropePMC

Gene, Volume 534, Issue 2, 6 1 2013, Pages 197-203 High prevalence of cerebral venous sinus thrombosis (CVST) as presentation of cystathionine beta-synthase deficiency in childhood: molecular and clinical findings of Turkish probands. Karaca M, Hismi B, Ozgul RK, Karaca S, Yilmaz DY, Coskun T, Sivri HS, Tokatli A, Dursun A

Classical homocystinuria is the most commonly inherited disorder of sulfur metabolism, caused by the genetic alterations in human cystathionine beta-synthase (CBS) gene. In this study, we present comprehensive clinical findings and the genetic basis of homocystinuria in a cohort of Turkish patients. Excluding some CBS mutations, detailed genotype-phenotype correlation for different CBS mutations has not been established in literature. We aimed to make clinical subgroups according to main clinica... Abstract

Cited 35 times since 2013 (3 per year) source: EuropePMC

Annals of surgery, Volume 258, Issue 5, 1 1 2013, Pages 743-51; discussion 752-3 The 14q32 microRNA-487b targets the antiapoptotic insulin receptor substrate 1 in hypertension-induced remodeling of the aorta. Nossent AY, Eskildsen TV, Andersen LB, Bie P, Brønnum H, Schneider M, Andersen DC, Welten SM, Jeppesen PL, Hamming JF, Hansen JL, Quax PH, Sheikh SP

Objectives: To study the role of microRNAs in hypertension-induced vascular pathology before the onset of symptoms of severe cardiovascular disease. Background: MicroRNAs play a crucial role in cardiovascular disease. However, microRNAs are often studied in full-blown cardiovascular disease models, not during development of cardiovascular pathology. Methods: Angiotensin II was infused into healthy adult rats, inducing chronic hypertension, and microRNA expression profiles were obtained. The most... Abstract

Cited 42 times since 2013 (3.6 per year) source: EuropePMC

Circulation. Cardiovascular imaging, Volume 7, Issue 1, 1 1 2013, Pages 74-81 Association between left ventricular global longitudinal strain and adverse left ventricular dilatation after ST-segment-elevation myocardial infarction. Joyce E, Hoogslag GE, Leong DP, Debonnaire P, Katsanos S, Boden H, Schalij MJ, Marsan NA, Bax JJ, Delgado V

Background: Myocardial infarct size is a major determinant of left ventricular (LV) remodeling after ST-segment-elevation myocardial infarction. We evaluated whether LV global longitudinal strain (GLS), proposed as a novel marker of infarct size, is associated with 3- and 6-month LV dilatation after ST-segment-elevation myocardial infarction. Methods and results: In the first ST-segment-elevation myocardial infarction patients treated with primary percutaneous coronary intervention, baseline LVG... Abstract

Cited 39 times since 2013 (3.4 per year) source: EuropePMC

Emerging infectious diseases, Volume 19, Issue 11, 1 1 2013, Pages 1797-1802 Transmissibility of livestock-associated methicillin-resistant Staphylococcus aureus. Hetem DJ, Bootsma MC, Troelstra A, Bonten MJ

Previous findings have suggested that the nosocomial transmission capacity of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is lower than that of other MRSA genotypes. We therefore performed a 6-month (June 1-November 30, 2011) nationwide study to quantify the single-admission reproduction number, RA, for LA-MRSA in 62 hospitals in the Netherlands and to compare this transmission capacity to previous estimates. We used spa typing for genotyping. Quantification of RA... Abstract

Cited 7 times since 2013 (0.6 per year) source: EuropePMC

Clinical chemistry and laboratory medicine, Volume 51, Issue 11, 1 1 2013, Pages 2187-2193 Assessment of plasma aminothiol levels and the association with recurrent atherothrombotic events in patients hospitalized for an acute coronary syndrome: a prospective study. Focks JJ, van Schaik A, Clappers N, van Dijk EG, van Oijen MG, Verheugt FW, Peters WH

Background: The aminothiols homocysteine and, to a lesser extent, cysteine have been associated with adverse cardiovascular outcome, whereas glutathione, as an antioxidant, may protect against atherosclerosis and thrombosis. Potentially, the combined assessment of these aminothiols may provide a more accurate association with future cardiovascular outcome. We evaluated the association between recurrent atherothrombotic events and the concentration of total plasma cysteine, homocysteine, and glut... Abstract

Cited 16 times since 2013 (1.4 per year) source: EuropePMC

Journal of electrocardiology, Volume 47, Issue 2, 1 1 2013, Pages 175-182 Electrocardiographic detection of right ventricular pressure overload in patients with suspected pulmonary hypertension. Kamphuis VP, Haeck ML, Wagner GS, Maan AC, Maynard C, Delgado V, Vliegen HW, Swenne CA

Background and purpose: Early, preferably noninvasive, detection of pulmonary hypertension improves prognosis. Our study evaluated the diagnostic accuracy of the electrocardiographically derived Butler-Leggett (BL) score and ventricular gradient (VG) to estimate mean pulmonary artery pressure (PAP). Methods: In 63 patients with suspected pulmonary hypertension, BL score and VG were calculated. The VG was projected on a direction optimized for detection of right ventricular pressure overload (VG-... Abstract

Cited 14 times since 2013 (1.2 per year) source: EuropePMC

European journal of anaesthesiology, Volume 30, Issue 11, 1 1 2013, Pages 685-694 Minimised closed circuit coronary artery bypass grafting in the elderly is associated with lower levels of organ-specific biomarkers: a prospective randomised study. van Boven WJ, Gerritsen WB, Driessen AH, van Dongen EP, Klautz RJ, Aarts LP

Background: Restrictive fluid management may protect organ function and improve postoperative outcome in elderly coronary artery bypass grafting (CABG) patients. Objective: We assessed organ-specific biomarker release to study the contribution of a fluid restrictive closed circuit concept to organ protection in elderly CABG patients. Cardiac, respiratory and abdominal organ injury was measured during and following minimal fluid coronary artery bypass grafting (mCABG), off-pump coronary artery by... Abstract

Cited 6 times since 2013 (0.5 per year) source: EuropePMC

Circulation. Cardiovascular imaging, Volume 6, Issue 6, 1 1 2013, Pages 855-857 Papillary muscle infarction, mitral regurgitation, and long-term prognosis. Bax JJ, Delgado V

Abstract

Cited 8 times since 2013 (0.7 per year) source: EuropePMC

Acta orthopaedica, Volume 84, Issue 5, 31 5 2013, Pages 489-494 Conversion to below-elbow cast after 3 weeks is safe for diaphyseal both-bone forearm fractures in children. Colaris JW, Allema JH, Biter LU, Reijman M, van de Ven CP, de Vries MR, Bloem RM, Kerver AJ, Verhaar JA

Background: It is unclear whether it is safe to convert above-elbow cast (AEC) to below-elbow cast (BEC) in a child who has sustained a displaced diaphyseal both-bone forearm fracture that is stable after reduction. In this multicenter study, we wanted to answer the question: does early conversion to BEC cause similar forearm rotation to that after treatment with AEC alone? Children and methods: Children were randomly allocated to 6 weeks of AEC, or 3 weeks of AEC followed by 3 weeks of BEC. The... Abstract

Cited 20 times since 2013 (1.7 per year) source: EuropePMC

Neurology, Volume 81, Issue 22, 30 5 2013, Pages 1922-1929 Total cerebral blood flow and mortality in old age: a 12-year follow-up study. Sabayan B, van der Grond J, Westendorp RG, Jukema JW, Ford I, Buckley BM, Sattar N, van Osch MJ, van Buchem MA, de Craen AJ

Objective: To examine the association of total cerebral blood flow (CBF) with all-cause, noncardiovascular, and cardiovascular mortality in older subjects at risk of cardiovascular disease. Methods: We included 411 subjects with a mean age of 74.5 years from the MRI substudy of the Prospective Study of Pravastatin in the Elderly at Risk. Total CBF was measured at baseline, and occurrence of death was recorded in an average follow-up period of 11.8 years. For each participant, total CBF was stand... Abstract

Cited 13 times since 2013 (1.1 per year) source: EuropePMC

Frontiers in cellular neuroscience, Volume 7, 30 5 2013, Pages 192 The adaptation of spike backpropagation delays in cortical neurons. Buskila Y, Morley JW, Tapson J, van Schaik A

We measured the action potential backpropagation delays in apical dendrites of layer V pyramidal neurons of the somatosensory cortex under different stimulation regimes that exclude synaptic involvement. These delays showed robust features and did not correlate to either transient change in the stimulus strength or low frequency stimulation of suprathreshold membrane oscillations. However, our results indicate that backpropagation delays correlate with high frequency (>10 Hz) stimulation of m... Abstract

Cited 21 times since 2013 (1.8 per year) source: EuropePMC

World journal of urology, Volume 32, Issue 3, 29 5 2013, Pages 651-659 The role of urine markers, white light cystoscopy and fluorescence cystoscopy in recurrence, progression and follow-up of non-muscle invasive bladder cancer. Karaoglu I, van der Heijden AG, Witjes JA

Non-muscle invasive bladder cancer (NMIBC) accounts for approximately 70 % of all bladder cancer cases and represents a heterogeneous pathological entity, characterized by a variable natural history and oncological outcome. The combination of cystoscopy and urine cytology is considered the gold standard in the initial diagnosis of bladder cancer, despite the limited sensitivity. The first step in NMIBC management is transurethral resection of the bladder tumour (TURBT). This procedure is marked... Abstract

Cited 1 times since 2013 (0.1 per year) source: EuropePMC

Journal of plastic, reconstructive & aesthetic surgery : JPRAS, Volume 67, Issue 3, 27 4 2013, Pages 411-412 Response from the authors of 'Treatment of infantile haemangiomas with atenolol: comparison with a historical propranolol group'. de Graaf M, Raphael MF, Breugem CC, Knol MJ, Bruijnzeel-Koomen CA, Kon M, Breur JM, Pasmans SG

Abstract

Cited 1 times since 2013 (0.1 per year) source: EuropePMC

Heart rhythm, Volume 11, Issue 8, 22 4 2013, Pages 1490-1491 Cardiac sympathetic innervation in a patient with catecholaminergic polymorphic ventricular tachycardia. Paul M, Kies P, Schäfers M, Schulze-Bahr E

Abstract

Cited 39 times since 2013 (3.4 per year) source: EuropePMC

Journal of vascular surgery, Volume 59, Issue 1, 18 3 2013, Pages 39-44.e1 Statin therapy is associated with improved survival after endovascular and open aneurysm repair. de Bruin JL, Baas AF, Heymans MW, Buimer MG, Prinssen M, Grobbee DE, Blankensteijn JD, DREAM Study Group

Background: The relationship between numerous risk factors and perioperative mortality after cardiovascular surgery has been studied extensively. While improved perioperative survival and fewer cardiovascular events have been related to statin therapy, its effect on long-term survival after aneurysm repair remains to be elucidated. The aim of this study is to determine the effect of statin therapy on long-term survival after open and endovascular aneurysm repair and to identify other cardiovascu... Abstract

Cited 2 times since 2013 (0.2 per year) source: EuropePMC

The American journal of case reports, Volume 14, 18 3 2013, Pages 419-423 Solitary paraganglioma of the hypoglossal nerve: A case report with magnetic resonance imaging findings. Beyazal M, Yavuz A, Unal O, Cankaya H, Yılmaz D

Patient: Female, 58 FINAL DIAGNOSIS: Solitary paraganglioma of the hypoglossal nerve Symptoms: Neck pain Medication: - Clinical Procedure: Surgical resection Specialty: Otolaryngology. Objective: Rare disease. Background: Paragangliomas are rare neuroendocrine tumors originating in the neural crest. Only a few cases of hypoglossal paraganglioma have been reported in the published literature. The localization of hypoglossal paragangliomas close to the carotid artery precludes determination of tum... Abstract

Cited 227 times since 2013 (19.5 per year) source: EuropePMC

European heart journal, Volume 35, Issue 8, 17 3 2013, Pages 501-507 Catheter ablation vs. antiarrhythmic drug treatment of persistent atrial fibrillation: a multicentre, randomized, controlled trial (SARA study). Mont L, Bisbal F, Hernández-Madrid A, Pérez-Castellano N, Viñolas X, Arenal A, Arribas F, Fernández-Lozano I, Bodegas A, Cobos A, Matía R, Pérez-Villacastín J, Guerra JM, Ávila P, López-Gil M, Castro V, Arana JI, Brugada J, SARA investigators

Background: Catheter ablation (CA) is a highly effective therapy for the treatment of paroxysmal atrial fibrillation (AF) when compared with antiarrhythmic drug therapy (ADT). No randomized studies have compared the two strategies in persistent AF. The present randomized trial aimed to compare the effectiveness of CA vs. ADT in treating persistent AF. Methods and results: Patients with persistent AF were randomly assigned to CA or ADT (excluding patients with long-standing persistent AF). Primar... Abstract

Cited 20 times since 2013 (1.7 per year) source: EuropePMC

International journal of cardiology, Volume 169, Issue 6, 11 2 2013, Pages 439-444 5-year serial follow-up of clinical condition and ventricular function in patients after repair of tetralogy of Fallot. Luijnenburg SE, Helbing WA, Moelker A, Kroft LJ, Groenink M, Roos-Hesselink JW, de Rijke YB, Hazekamp MG, Bogers AJ, Vliegen HW, Mulder BJ

Objective: To study the changes over time in biventricular size and function, and clinical parameters in patients after repair of tetralogy of Fallot (TOF) without subsequent pulmonary valve replacement (PVR). Methods: We prospectively included 78 non-PVR patients (age 20(6-60)years at baseline), who were studied twice with a 5-year interval. Patients underwent magnetic resonance imaging for assessment of biventricular size and function. Exercise testing and electrocardiography were performed to... Abstract

Cited 29 times since 2013 (2.5 per year) source: EuropePMC

Respiratory medicine, Volume 108, Issue 2, 10 2 2013, Pages 351-357 Association of lung function measurements and visceral fat in men with metabolic syndrome. Thijs W, Alizadeh Dehnavi R, Hiemstra PS, de Roos A, Melissant CF, Janssen K, Tamsma JT, Rabe KF

Background: Several studies have reported a positive relationship between lung function impairment and the metabolic syndrome. This is most usually explained by abdominal adiposity. We hypothesized that the main determinant of the association between lung function impairment and abdominal obesity is the presence of visceral fat. Methods: The present study is a cross-sectional analysis of 98 non-diabetic men aged between 50 and 70 years with the metabolic syndrome. The amount of visceral and subc... Abstract