8684 results
Cited 14 times since 2013 (1.2 per year)
source: EuropePMC
Atherosclerosis,
Volume 231, Issue 2, 10 2 2013, Pages 346-351
Increased cytokine response after toll-like receptor stimulation in patients with stable coronary artery disease.
Elsenberg EH, Sels JE, Hillaert MA, Schoneveld AH, van den Dungen NA, van Holten TC, Roest M, Jukema JW, van Zonneveld AJ, de Groot PG, Pijls N, Pasterkamp G, Hoefer IE
Objective: Atherosclerosis is associated with increased levels of plasma cytokines and expression of Toll-like receptors (TLRs). Yet, little is known about the potential use of TLR ligand induced cytokine release as a biomarker of coronary artery disease (CAD). In this study, we investigated whether TLR ligand induced cytokine release is associated with atherosclerotic disease severity and its predictive value for future cardiovascular events. Methods: Blood samples were obtained from 260 patien...
Abstract
Cited 17 times since 2013 (1.5 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 33, Issue 12, 10 2 2013, Pages 2810-2817
An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation.
Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH
Objective: In atherosclerosis, Toll-like receptors (TLRs) are traditionally linked to effects on tissue macrophages or foam cells. RP105, a structural TLR4 homolog, is an important regulator of TLR signaling. The effects of RP105 on TLR signaling vary for different leukocyte subsets known to be involved in atherosclerosis, making it unique in its role of either suppressing (in myeloid cells) or enhancing (in B cells) TLR-regulated inflammation in different cell types. We aimed to identify a role...
Abstract
Cited 1 times since 2013 (0.1 per year)
source: EuropePMC
Journal of microscopy,
Volume 252, Issue 3, 9 2 2013, Pages 263-274
Microscopic characterization of defect structure in RDX crystals.
Bouma RH, Duvalois W, Van der Heijden AE
Three batches of the commercial energetic material RDX, as received from various production locations and differing in sensitivity towards shock initiation, have been characterized with different microscopic techniques in order to visualize the defect content in these crystals. The RDX crystals are embedded in an epoxy matrix and cross-sectioned. By a treatment of grinding and polishing of the crystals, the internal defect structure of a multitude of energetic crystals can be visualized using op...
Abstract
Cited 17 times since 2013 (1.5 per year)
source: EuropePMC
Journal of sex & marital therapy,
Volume 40, Issue 4, 8 2 2013, Pages 309-322
Quality of sexual life and its effect on marital adjustment of Turkish women in pregnancy.
Kisa S, Zeyneloğlu S, Yilmaz D, Güner T
Pregnancy is an important period of a woman's life that can affect marital relationships because of decrease in the sexual function. This study aimed to examine the effect of sexual life on the marital adjustment of 607 healthy, pregnant women using the self-administered Sexual Quality of Life Questionnaire-Female and the Marital Adjustment Scale. Results showed that 30% of the pregnant women experienced problems during sexual intercourse and 50% had painful intercourse. The median total sc...
Abstract
Cited 48 times since 2013 (4.1 per year)
source: EuropePMC
Head & neck,
Volume 36, Issue 6, 4 1 2013, Pages 853-858
Intraoperative near-infrared fluorescence imaging of parathyroid adenomas with use of low-dose methylene blue.
van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Tummers QR, Hutteman M, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL
Background: Intraoperative identification of parathyroid adenomas can be challenging. We hypothesized that low-doses methylene blue (MB) and near-infrared fluorescence (NIRF) imaging could be used to identify parathyroid adenomas intraoperatively. Methods: MB was injected intravenously after exploration at a dose of 0.5 mg/kg into 12 patients who underwent parathyroid surgery. NIRF imaging was performed using the Mini-FLARE imaging system. Results: In 10 of 12 patients, histology confirmed a par...
Abstract
Cited 13 times since 2013 (1.1 per year)
source: EuropePMC
Injury,
Volume 45, Issue 4, 3 1 2013, Pages 696-700
Which factors affect limitation of pronation/supination after forearm fractures in children? A prospective multicentre study.
Colaris JW, Allema JH, Reijman M, de Vries MR, Ulas Biter L, Bloem RM, van de Ven CP, Verhaar JA
Introduction: Both-bone forearm fractures in children frequently result in a limitation of pronation/supination, which hinders daily activities. The purpose of this prospective multicentre study was to investigate which clinical factors are related to the limitation of pronation/supination in children with a both-bone forearm fracture. Methods: In four Dutch hospitals, consecutive children (
Abstract
Cited 4 times since 2013 (0.3 per year)
source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
Volume 28, Issue 12, 3 1 2013, Pages 3045-3052
Echocardiographical determinants of an abnormal spatial QRS-T angle in chronic dialysis patients.
de Bie MK, Ajmone Marsan N, Gaasbeek A, Bax JJ, Delgado V, Rabelink TJ, Schalij MJ, Jukema JW
Background: The spatial QRS-T angle describes the relation between ventricular depolarization and repolarization. Having a wide (abnormal) angle is considered an important predictor of arrhythmic events. Given the high incidence of sudden cardiac death in dialysis patients, this parameter is of particular interest in this patient group. The objective of this study was to assess the association of (modifiable) echocardiographic parameters and an abnormal spatial QRS-T angle in dialysis patients....
Abstract
Cited 3 times since 2013 (0.3 per year)
source: EuropePMC
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 46, Issue 6, 2 1 2013, Pages 719-725
Vascular training profiles across Europe.
Avgerinos ED, European Vascular Surgeons in Training (EVST) Writing Committee
Background: The European Vascular Surgeons in Training (EVST) were appointed by the European Society for Vascular Surgery to review the current status and developments regarding training and certification in vascular surgery (VS) across Europe. Methods: An e-mail-based survey was distributed to EVST representatives in 33 countries. The questionnaire examined the current structure of vascular surgery training and certification (monospecialty, subspecialty, no specialty), as well as the evolving r...
Abstract
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 9, Issue 6, 1 1 2013, Pages 761-4, 3 p following p764
How should I treat acute left main coronary obstruction after transapical aortic valve implantation?
Nazeri I, Abdi S, Mandegar MH, Naemi S, Roshanali F, Tehrai M, Shahabi P, Debonnaire P, van der Kley F, Katsanos S, Delgado V, Van Mieghem NM
Abstract
Cited 28 times since 2013 (2.4 per year)
source: EuropePMC
International journal of epidemiology,
Volume 42, Issue 5, 1 1 2013, Pages 1371-1380
Parental smoking during pregnancy and cardiovascular structures and function in childhood: the Generation R Study.
Taal HR, de Jonge LL, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, van der Heijden AJ, Jaddoe VW
Background: Foetal smoke exposure might lead to foetal developmental adaptations that permanently affect the cardiovascular system. We assessed the associations of both maternal and paternal smoking during pregnancy with childhood cardiovascular structures and function. Method: In a prospective cohort study among 5565 children, we examined whether maternal and paternal smoking during pregnancy are associated with blood pressure, carotid-femoral pulse wave velocity and left cardiac structures and...
Abstract
Cited 10 times since 2013 (0.9 per year)
source: EuropePMC
Cardiovascular drugs and therapy,
Volume 27, Issue 5, 1 1 2013, Pages 433-439
Long term effects of epoetin alfa in patients with ST- elevation myocardial infarction.
Fokkema ML, Kleijn L, van der Meer P, Belonje AM, Achterhof SK, Hillege HL, van 't Hof A, Jukema JW, Peels HO, Henriques JP, ten Berg JM, Vos J, van Gilst WH, van Veldhuisen DJ, Voors AA
Purpose: The HEBE III trial showed that epoetin alfa administration in patients with a first ST-elevation myocardial infarction (STEMI) did not improve left ventricular function at 6 weeks after primary percutaneous coronary intervention (PCI). The long term effects of erythropoiesis- stimulating agents on cardiovascular morbidity and mortality are unknown, therefore we evaluated clinical events at 1 year after PCI. Methods: A total of 529 patients with a first STEMI and successful primary PCI w...
Abstract
Cited 55 times since 2013 (4.7 per year)
source: EuropePMC
Therapeutic drug monitoring,
Volume 35, Issue 5, 1 1 2013, Pages 608-616
Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines.
Elens L, Capron A, van Schaik RH, De Meyer M, De Pauw L, Eddour DC, Latinne D, Wallemacq P, Mourad M, Haufroid V
Background: Tacrolimus (Tac) metabolism is mainly mediated by the cytochrome P450 3A (CYP3A) subfamily. Recently, it has been reported that kidney transplant recipients carrying the CYP3A4*22 decrease-of-function allele require lower Tac doses and are more at risk of Tac overexposure than CYP3A4*1/*1 patients. This effect was shown to be independent of the CYP3A5*3 allelic status. However, the pharmacokinetic (PK) parameters assessed in previous studies were limited on single time point whole bl...
Abstract
Cited 10 times since 2013 (0.9 per year)
source: EuropePMC
Current pain and headache reports,
Volume 17, Issue 10, 1 1 2013, Pages 365
Fabry disease: a rare cause of neuropathic pain.
Biegstraaten M, Linthorst GE, van Schaik IN, Hollak CE
Fabry disease is characterized by burning or shooting pains in hands and feet, which have a severe impact on the quality of life of patients. It is therefore of importance that Fabry patients receive adequate diagnosis, counseling, treatment and follow up. This review describes neuropathic pain in classical Fabry disease with the aim to help clinicians to recognize Fabry patients among patients presenting with chronic extremity pain. The diagnostic dilemmas in patients with neuropathic pain and...
Abstract
Cited 32 times since 2013 (2.7 per year)
source: EuropePMC
Current opinion in neurology,
Volume 26, Issue 5, 1 1 2013, Pages 496-502
Chronic inflammatory demyelinating polyradiculoneuropathy: update on clinical features, phenotypes and treatment options.
Eftimov F, van Schaik I
Purpose of review: In this review, we focus on less recognised signs and symptoms in typical chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and on the clinical presentation, course of disease and response to treatment of the atypical CIDP phenotypes. Recent findings: Frequently occurring and often disabling symptoms in CIDP such as fatigue, pain and tremor have recently been emphasised, whereas autonomic dysfunction, if present, is usually mild. Sensory CIDP is probably the mos...
Abstract
Cited 4 times since 2013 (0.3 per year)
source: EuropePMC
Indian dermatology online journal,
Volume 4, Issue 4, 1 1 2013, Pages 369-371
A cases series of Piezogenic pedal papules.
Karadag AS, Bilgili SG, Guner S, Yilmaz D
Abstract
Cited 14 times since 2013 (1.2 per year)
source: EuropePMC
Journal of African earth sciences (Oxford, England : 1994),
Volume 86, 1 1 2013, Pages 65-106
Orogen styles in the East African Orogen: A review of the Neoproterozoic to Cambrian tectonic evolution.
Fritz H, Abdelsalam M, Ali KA, Bingen B, Collins AS, Fowler AR, Ghebreab W, Hauzenberger CA, Johnson PR, Kusky TM, Macey P, Muhongo S, Stern RJ, Viola G
The East African Orogen, extending from southern Israel, Sinai and Jordan in the north to Mozambique and Madagascar in the south, is the world́s largest Neoproterozoic to Cambrian orogenic complex. It comprises a collage of individual oceanic domains and continental fragments between the Archean Sahara-Congo-Kalahari Cratons in the west and Neoproterozoic India in the east. Orogen consolidation was achieved during distinct phases of orogeny between ∼850 and 550 Ma. The northern part of the oroge...
Abstract
Cited 7 times since 2013 (0.6 per year)
source: EuropePMC
Computational and mathematical methods in medicine,
Volume 2013, 30 5 2013, Pages 238937
Comparison of SVM and ANFIS for snore related sounds classification by using the largest Lyapunov exponent and entropy.
Ankışhan H, Yılmaz D
Snoring, which may be decisive for many diseases, is an important indicator especially for sleep disorders. In recent years, many studies have been performed on the snore related sounds (SRSs) due to producing useful results for detection of sleep apnea/hypopnea syndrome (SAHS). The first important step of these studies is the detection of snore from SRSs by using different time and frequency domain features. The SRSs have a complex nature that is originated from several physiological and physic...
Abstract
Cited 54 times since 2013 (4.6 per year)
source: EuropePMC
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology,
Volume 33, Issue 4, 29 5 2013, Pages 479-490
Determinants of virulence of influenza A virus.
Schrauwen EJ, de Graaf M, Herfst S, Rimmelzwaan GF, Osterhaus AD, Fouchier RA
Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and the accumulation of mutations contribute to the emergence of new influenza A virus variants. Fortunately, most of these variants do not have the...
Abstract
Cited 28 times since 2013 (2.4 per year)
source: EuropePMC
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA,
Volume 25, Issue 3, 27 4 2013, Pages 875-885
The societal costs of femoral neck fracture patients treated with internal fixation.
Zielinski SM, Bouwmans CA, Heetveld MJ, Bhandari M, Patka P, Van Lieshout EM, FAITH trial investigators
Summary: The study rationale was to provide a detailed overview of the costs for femoral neck fracture treatment with internal fixation in the Netherlands. Mean total costs per patient at 2-years follow-up were 19,425. Costs were higher for older, less healthy patients. Results are comparable to internationally published costs. Introduction: The aim of this study was to provide a detailed overview of the cost and healthcare consumption of patients treated for a hip fracture with internal fixatio...
Abstract
Cited 6 times since 2013 (0.5 per year)
source: EuropePMC
Heart and vessels,
Volume 29, Issue 5, 27 4 2013, Pages 619-628
Prognostic implications of left ventricular regional function heterogeneity assessed with two-dimensional speckle tracking in patients with ST-segment elevation myocardial infarction and depressed left ventricular ejection fraction.
Hoogslag GE, Thijssen J, Höke U, Boden H, Antoni ML, Debonnaire P, Haeck ML, Holman ER, Bax JJ, Ajmone Marsan N, Schalij MJ, Delgado V
The aim of the current study was to evaluate the prognostic implications of myocardial tissue heterogeneity assessed with two-dimensional speckle-tracking echocardiography in patients three months after first ST-segment elevation myocardial infarction (STEMI) with left ventricular ejection fraction (LVEF) ≤35 %. For this purpose, a total of 79 patients with first STEMI and LVEF ≤35 % at three months postinfarction were evaluated. Based on left ventricular (LV) speckle-tracking longitudinal strai...
Abstract
