9026 results
Cited 46 times since 2020 (8.9 per year)
source: EuropePMC
Frontiers in pharmacology,
Volume 11, 11 2 2020, Pages 575540
Pharmacogenetics in Psychiatry: An Update on Clinical Usability.
van Schaik RHN, Müller DJ, Serretti A, Ingelman-Sundberg M
Using pharmacogenetics in guiding drug therapy experiences a steady increase in uptake, although still leads to discussions as to its clinical use. Psychiatry constitutes a field where pharmacogenomic testing might help in guiding drug therapy. To address current challenges, this minireview provides an update regarding genotyping (SNP analysis/arrays/NGS), structural variant detection (star-alleles/CNVs/hybrid alleles), genotype-to-phenotype translations, cost-effectiveness, and actionability of...
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 34, Issue 1, 10 2 2020, Pages 20-29
The Obesity Paradox in Patients with Significant Tricuspid Regurgitation: Effects of Obesity on Right Ventricular Remodeling and Long-Term Prognosis.
Dietz MF, Prihadi EA, van der Bijl P, Ajmone Marsan N, Bax JJ, Delgado V
Background: Obesity may cause right ventricular (RV) remodeling due to volume overload. However, obesity is also associated with better prognosis compared with normal weight in patients with various cardiac diseases. The aim of this study was to assess the impact of obesity on RV remodeling and long-term prognosis in patients with significant (moderate and severe) tricuspid regurgitation (TR). Methods: A total of 951 patients with significant TR (median age, 70 years; interquartile range, 61-77 ...
Abstract
Cited 54 times since 2020 (10.4 per year)
source: EuropePMC
Neurology,
Volume 95, Issue 24, 10 2 2020, Pages e3331-e3343
Association of common genetic variants with brain microbleeds: A genome-wide association study.
Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS, Alzheimer's Disease Neuroimaging Initiative
Objective: To identify common genetic variants associated with the presence of brain microbleeds (BMBs). Methods: We performed genome-wide association studies in 11 population-based cohort studies and 3 case-control or case-only stroke cohorts. Genotypes were imputed to the Haplotype Reference Consortium or 1000 Genomes reference panel. BMBs were rated on susceptibility-weighted or T2*-weighted gradient echo MRI sequences, and further classified as lobar or mixed (including strictly deep and inf...
Abstract
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
Medical education,
Volume 54, Issue 11, 10 2 2020, Pages 972-974
Medical trainees as job crafters: Looking at identity formation through another lens.
Bochatay N, van Schaik S, O'Brien B
Abstract
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
Pediatrics international : official journal of the Japan Pediatric Society,
Volume 62, Issue 9, 9 2 2020, Pages 1094-1100
Efficacy of Buzzy<sup>®</sup> on pain and anxiety during catheterization in children.
Yılmaz D, Özyazıcıoğlu N, Çıtak Tunç G, Aydın Aİ, Atak M, Duygulu Ş, Demirtaş Z
Background: The use of a peripheral intravenous cannula is a common clinical practice, and it is known to be a major source of pain and anxiety in children. The aim of this study was to examine the effect of the use of the Buzzy® on pain and anxiety in children during peripheral cannula application. Methods: The research sample consisted of 60 children between the ages of 8 and 16. For children in the experimental group, external cold and vibration were applied by means of the Buzzy® device. Bef...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Radiology case reports,
Volume 15, Issue 11, 7 1 2020, Pages 2205-2207
Antegrade common femoral artery access site closure using the MANTA vascular closure device.
Stomp W, Eefting D, van Schaik J, Sudiono DR, van der Meer RW
In antegrade peripheral endovascular procedures, the use of covered stents may require a large sheath size, which precludes the use of regular closure devices. The MANTA vascular closure device is a collagen plug-based vascular closure device for large bore percutaneous arterial interventions, which is normally used to close retrograde vascular access sites. We describe successful antegrade common femoral access site closure with the MANTA vascular closure device in 2 patients, a 68-year-old mal...
Abstract
Cited 10 times since 2020 (1.9 per year)
source: EuropePMC
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Volume 375, Issue 1810, 7 1 2020, Pages 20190509
Spring enhancement and summer reduction in carbon uptake during the 2018 drought in northwestern Europe.
Smith NE, Kooijmans LMJ, Koren G, van Schaik E, van der Woude AM, Wanders N, Ramonet M, Xueref-Remy I, Siebicke L, Manca G, Brümmer C, Baker IT, Haynes KD, Luijkx IT, Peters W
We analysed gross primary productivity (GPP), total ecosystem respiration (TER) and the resulting net ecosystem exchange (NEE) of carbon dioxide (CO2) by the terrestrial biosphere during the summer of 2018 through observed changes across the Integrated Carbon Observation System (ICOS) network, through biosphere and inverse modelling, and through remote sensing. Highly correlated yet independently-derived reductions in productivity from sun-induced fluorescence, vegetative near-infrared reflectan...
Abstract
Cited 11 times since 2020 (2.1 per year)
source: EuropePMC
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Volume 375, Issue 1810, 7 1 2020, Pages 20190512
Changes in net ecosystem exchange over Europe during the 2018 drought based on atmospheric observations.
Thompson RL, Broquet G, Gerbig C, Koch T, Lang M, Monteil G, Munassar S, Nickless A, Scholze M, Ramonet M, Karstens U, van Schaik E, Wu Z, Rödenbeck C
The 2018 drought was one of the worst European droughts of the twenty-first century in terms of its severity, extent and duration. The effects of the drought could be seen in a reduction in harvest yields in parts of Europe, as well as an unprecedented browning of vegetation in summer. Here, we quantify the effect of the drought on net ecosystem exchange (NEE) using five independent regional atmospheric inversion frameworks. Using a network of atmospheric CO2 mole fraction observations, we estim...
Abstract
Cited 88 times since 2020 (17 per year)
source: EuropePMC
EMBO reports,
Volume 21, Issue 11, 7 1 2020, Pages e50636
Cell cycle dynamics of lamina-associated DNA.
van Schaik T, Vos M, Peric-Hupkes D, Hn Celie P, van Steensel B
In mammalian interphase nuclei, more than one thousand large genomic regions are positioned at the nuclear lamina (NL). These lamina-associated domains (LADs) are involved in gene regulation and may provide a backbone for the folding of interphase chromosomes. Little is known about the dynamics of LADs during interphase, in particular at the onset of G1 phase and during DNA replication. We developed an antibody-based variant of the DamID technology (named pA-DamID) that allows us to map and visu...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 71, 3 1 2020, Pages 411-418
Stent Graft Sizing for Endovascular Abdominal Aneurysm Repair Using Open Source Image Processing Software.
Knöps E, van Schaik J, van der Bogt KEA, Veger HTC, Putter H, Waasdorp EJ, van der Vorst JR
Introduction: An important step to reach a favorable outcome of abdominal endovascular aneurysm repair (EVAR) is preoperative sizing of the stent graft using computed tomography angiography (CTA) images of the abdominal aorta. A variety of costly image processing software options is available to obtain the necessary aortic measurements. A package that can be used for EVAR sizing is OsiriX Lite®-an open source, freely downloadable image processing option. This study assesses the concurrent validi...
Abstract
Cited 49 times since 2020 (9.4 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 22, Issue 9, 2 1 2020, Pages e20953
Telemonitoring for Patients With COVID-19: Recommendations for Design and Implementation.
Silven AV, Petrus AHJ, Villalobos-Quesada M, Dirikgil E, Oerlemans CR, Landstra CP, Boosman H, van Os HJA, Blanker MH, Treskes RW, Bonten TN, Chavannes NH, Atsma DE, Teng YKO
Despite significant efforts, the COVID-19 pandemic has put enormous pressure on health care systems around the world, threatening the quality of patient care. Telemonitoring offers the opportunity to carefully monitor patients with a confirmed or suspected case of COVID-19 from home and allows for the timely identification of worsening symptoms. Additionally, it may decrease the number of hospital visits and admissions, thereby reducing the use of scarce resources, optimizing health care capacit...
Abstract
Cited 5 times since 2020 (1 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 21, Issue 17, 2 1 2020, Pages E6364
Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning Methods.
Zhang H, Bredewold EOW, Vreeken D, Duijs JMGJ, de Boer HC, Kraaijeveld AO, Jukema JW, Pijls NH, Waltenberger J, Biessen EAL, van der Veer EP, van Zonneveld AJ, van Gils JM
Atherosclerosis is the underlying pathology in a major part of cardiovascular disease, the leading cause of mortality in developed countries. The infiltration of monocytes into the vessel walls of large arteries is a key denominator of atherogenesis, making monocytes accountable for the development of atherosclerosis. With the development of high-throughput transcriptome profiling platforms and cytometric methods for circulating cells, it is now feasible to study in-depth the predicted functiona...
Abstract
Cited 50 times since 2020 (9.6 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 34, 1 1 2020, Pages 3255-3268
Coexistence and outcome of coronary artery disease in Takotsubo syndrome.
Napp LC, Cammann VL, Jaguszewski M, Szawan KA, Wischnewsky M, Gili S, Knorr M, Heiner S, Citro R, Bossone E, D'Ascenzo F, Neuhaus M, Franke J, Sorici-Barb I, Noutsias M, Burgdorf C, Koenig W, Kherad B, Sarcon A, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Pott A, Meyer P, Arroja JD, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Hauck C, Paolini C, Bilato C, Imori Y, Kato K, Kobayashi Y, Opolski G, Budnik M, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Dichtl W, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, El-Battrawy I, Akin I, Gilyarova E, Shilova A, Gilyarov M, Horowitz JD, Polednikova K, Tousek P, Widimský P, Winchester DE, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Di Mario C, Prasad A, Rihal CS, Schulze PC, Bianco M, Crea F, Borggrefe M, Maier LS, Pinto FJ, Braun-Dullaeus RC, Rottbauer W, Katus HA, Hasenfuß G, Tschöpe C, Pieske BM, Thiele H, Schunkert H, Böhm M, Felix SB, Münzel T, Bax JJ, Bauersachs J, Braunwald E, Lüscher TF, R
Aims: Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a large cohort of patients with TTS. Methods and results: Coronary anatomy and CAD were s...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 2, 1 1 2020, Pages 649-651
Autonomic dysfunction in Huntington's disease: A <sup>123</sup>I-MIBG study.
Ng ACT, Delgado V, Bax JJ
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 9, 1 1 2020, Pages 959-960
An international, multicentre survey of echocardiographic abnormalities in COVID-19 patients.
Ng ACT, Delgado V, Bax JJ
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists,
Volume 39, Issue 5, 1 1 2020, Pages 420-427
Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer.
Kortekaas KE, Van de Vijver KK, van Poelgeest MIE, Gilks CB, Smit VTHBM, Arif S, Arora D, Faruqi A, Ganesan R, Griffin NR, Hale R, Hock YE, Horn LC, McCluggage WG, Mukonoweshuro P, Park KJ, Rous B, Tanchel B, Van Rompuy AS, van Schalkwyk G, Vella J, Vergine M, Singh N, Bosse T
Surgical resection with free surgical margins is the cornerstone of successful primary treatment of vulvar squamous cell carcinoma (VSCC). In general reexcision is recommended when the minimum peripheral surgical margin (MPSM) is
Abstract
Cited 27 times since 2020 (5.2 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 9, 1 1 2020, Pages 973-980
Non-obstructive high-risk plaques increase the risk of future culprit lesions comparable to obstructive plaques without high-risk features: the ICONIC study.
Ferraro RA, van Rosendael AR, Lu Y, Andreini D, Al-Mallah MH, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, de Araújo Gonçalves P, Hadamitzky M, Kim YJ, Leipsic J, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Lee SE, Al'Aref SJ, Baskaran L, Cho I, Danad I, Gransar H, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Berman DS, Chang HJ, Bax JJ, Min JK, Shaw LJ, Lin FY
Aims: High-risk plaque (HRP) and non-obstructive coronary artery disease independently predict adverse events, but their importance to future culprit lesions has not been resolved. We sought to determine in patients prior to confirmed acute coronary syndrome (ACS) the association between lesion percent diameter stenosis (%DS), and the absolute number and prevalence of HRP. The secondary objective was to examine the relative importance of non-obstructive HRP in future culprit lesions. Methods and...
Abstract
Cited 33 times since 2020 (6.4 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 33, 1 1 2020, Pages 3184-3197
Leaflet immobility and thrombosis in transcatheter aortic valve replacement.
Ng ACT, Holmes DR, Mack MJ, Delgado V, Makkar R, Blanke P, Leipsic JA, Leon MB, Bax JJ
Transcatheter aortic valve replacement (TAVR) has grown exponentially worldwide in the last decade. Due to the higher bleeding risks associated with oral anticoagulation and in patients undergoing TAVR, antiplatelet therapy is currently considered first-line antithrombotic treatment after TAVR. Recent studies suggest that some patients can develop subclinical transcatheter heart valve (THV) thrombosis after the procedure, whereby thrombus forms on the leaflets that can be a precursor to leaflet...
Abstract
Cited 176 times since 2020 (33.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 76, Issue 9, 1 1 2020, Pages 1018-1030
Bicuspid Aortic Valve Morphology and Outcomes After Transcatheter Aortic Valve Replacement.
Yoon SH, Kim WK, Dhoble A, Milhorini Pio S, Babaliaros V, Jilaihawi H, Pilgrim T, De Backer O, Bleiziffer S, Vincent F, Shmidt T, Butter C, Kamioka N, Eschenbach L, Renker M, Asami M, Lazkani M, Fujita B, Birs A, Barbanti M, Pershad A, Landes U, Oldemeyer B, Kitamura M, Oakley L, Ochiai T, Chakravarty T, Nakamura M, Ruile P, Deuschl F, Berman D, Modine T, Ensminger S, Kornowski R, Lange R, McCabe JM, Williams MR, Whisenant B, Delgado V, Windecker S, Van Belle E, Sondergaard L, Chevalier B, Mack M, Bax JJ, Leon MB, Makkar RR, Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry Investigators
Background: Bicuspid aortic stenosis accounts for almost 50% of patients undergoing surgical aortic valve replacement in the younger patients. Expanding the indication of transcatheter aortic valve replacement (TAVR) toward lower-risk and younger populations will lead to increased use of TAVR for patients with bicuspid aortic valve (BAV) stenosis despite the exclusion of bicuspid anatomy in all pivotal clinical trials. Objectives: This study sought to evaluate the association of BAV morphology a...
Abstract
JACC. Clinical electrophysiology,
Volume 6, Issue 9, 1 1 2020, Pages 1191-1192
Reply: Debating the Definition and Incidence of Isolated Cardiac Sarcoidosis.
Hoogendoorn JC, Bogun FM, Tedrow UB, Stevenson WG, Zeppenfeld K
Abstract
