6205 results
Cited 25 times since 2012 (1.9 per year)
source: EuropePMC
Diabetes & vascular disease research,
Volume 10, Issue 2, 23 4 2012, Pages 123-134
Non-invasive assessment of microcirculation by sidestream dark field imaging as a marker of coronary artery disease in diabetes.
Djaberi R, Schuijf JD, de Koning EJ, Wijewickrama DC, Pereira AM, Smit JW, Kroft LJ, Roos Ad, Bax JJ, Rabelink TJ, Jukema JW
Purpose: In diabetes, generalised microvascular disease and coronary artery disease (CAD) are likely to occur in parallel. We used a sidestream dark field (SDF) handheld imaging device to determine the relation between the labial microcirculation parameters and CAD in asymptomatic patients with diabetes. Methods: SDF imaging was validated for assessment of labial capillary density and tortuosity. Thereafter, mean labial capillary density and tortuosity were evaluated and compared in non-diabetic...
Abstract
Cited 625 times since 2012 (47.9 per year)
source: EuropePMC
Nature genetics,
Volume 44, Issue 6, 13 2 2012, Pages 659-669
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G,
Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways might be uncovered by accounting for differences in body mass index (BMI) and potential interactions between BMI and genetic variants. We applied a joint meta-analysis approach to test associations w...
Abstract
Cited 11 times since 2012 (0.8 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 29, Issue 1, 11 2 2012, Pages 221-228
Non-invasive computed tomography coronary angiography as a gatekeeper for invasive coronary angiography.
de Graaf FR, van Velzen JE, de Boer SM, van Werkhoven JM, Kroft LJ, de Roos A, Sieders A, de Grooth GJ, Jukema JW, Schuijf JD, Bax JJ, Schalij MJ, van der Wall EE
To determine the rate of subsequent invasive coronary angiography (ICA) and revascularization in relation to computed tomography coronary angiography (CTA) results. In addition, independent determinants of subsequent ICA and revascularization were evaluated. CTA studies were performed using a 64-row (n = 413) or 320-row (n = 224) multidetector scanner. The presence and severity of CAD were determined on CTA. Following CTA, patients were followed up for 1 year for the occurrence of ICA and revasc...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 42, Issue 1, 10 2 2012, Pages 31-32
Reoperations after paediatric Ross operation.
Hazekamp MG
Abstract
Cited 23 times since 2012 (1.8 per year)
source: EuropePMC
International journal of nephrology,
Volume 2012, 9 2 2012, Pages 963504
Left ventricular diastolic dysfunction in dialysis patients assessed by novel speckle tracking strain rate analysis: prevalence and determinants.
de Bie MK, Ajmone Marsan N, Gaasbeek A, Bax JJ, Groeneveld M, Gabreels BA, Delgado V, Rabelink TJ, Schalij MJ, Jukema JW
Background. Diastolic dysfunction is common among dialysis patients and is associated with increased morbidity and mortality. Novel echocardiographic speckle tracking strain analysis permits accurate assessment of left ventricular diastolic function, independent of loading conditions and taking all myocardial segments into account. The aim of the study was to evaluate the prevalence of diastolic dysfunction in chronic dialysis patients using this novel technique, and to identify its determinants...
Abstract
Cited 7 times since 2012 (0.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 13, Issue 12, 7 1 2012, Pages 1041-1046
Temporal evolution of left ventricular dyssynchrony after myocardial infarction: relation with changes in left ventricular systolic function.
Nucifora G, Bertini M, Ajmone Marsan N, Scholte AJ, Siebelink HM, Holman ER, Schalij MJ, van der Wall EE, Bax JJ, Delgado V
Aims: The relationship between temporal changes in left ventricular (LV) dyssynchrony and LV functional recovery after acute myocardial infarction (MI) remains unclear. Accordingly, the aim of the present study was to evaluate the temporal evolution of LV synchronicity after acute MI, and to explore the relationship between changes in LV systolic function and LV synchronicity. Methods and results: In 193 patients with a first acute MI, LV dyssynchrony (SDI) and global systolic function were eval...
Abstract
Cited 51 times since 2012 (3.9 per year)
source: EuropePMC
Trials,
Volume 13, 6 1 2012, Pages 54
Open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery ERAS® programme (ORANGE II-trial): study protocol for a randomised controlled trial.
van Dam RM, Wong-Lun-Hing EM, van Breukelen GJ, Stoot JH, van der Vorst JR, Bemelmans MH, Olde Damink SW, Lassen K, Dejong CH, ORANGE II Study Group
Background: The use of lLaparoscopic liver resection in terms of time to functional recovery, length of hospital stay (LOS), long-term abdominal wall hernias, costs and quality of life (QOL) has never been studied in a randomised controlled trial. Therefore, this is the subject of the international multicentre randomised controlled ORANGE II trial. Methods: Patients eligible for left lateral sectionectomy (LLS) of the liver will be recruited and randomised at the outpatient clinic. All randomise...
Abstract
Cited 29 times since 2012 (2.2 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 5, 4 1 2012, Pages e36115
Myocardial structural alteration and systolic dysfunction in preclinical hypertrophic cardiomyopathy mutation carriers.
Yiu KH, Atsma DE, Delgado V, Ng AC, Witkowski TG, Ewe SH, Auger D, Holman ER, van Mil AM, Breuning MH, Tse HF, Bax JJ, Schalij MJ, Marsan NA
Background: To evaluate the presence of myocardial structural alterations and subtle myocardial dysfunction during familial screening in asymptomatic mutation carriers without hypertrophic cardiomyopathy (HCM) phenotype. Methods and findings: Sixteen HCM families with pathogenic mutation were studied and 46 patients with phenotype expression (Mut+/Phen+) and 47 patients without phenotype expression (Mut+/Phen-) were observed. Twenty-five control subjects, matched with the Mut+/Phen- group, were...
Abstract
Cited 50 times since 2012 (3.8 per year)
source: EuropePMC
American journal of respiratory and critical care medicine,
Volume 186, Issue 2, 3 1 2012, Pages 181-189
Left ventricular dysfunction induced by nonsevere idiopathic pulmonary arterial hypertension: a pressure-volume relationship study.
Kasner M, Westermann D, Steendijk P, Dröse S, Poller W, Schultheiss HP, Tschöpe C
Rationale: Severe increase in right ventricular pressure can compromise left ventricular (LV) function because of impaired interventricular interaction and aggravate the symptoms. Objectives: To elucidate how nonsevere idiopathic pulmonary arterial hypertension (IPAH) influences LV function because of impaired interventricular interaction. Methods: Invasive pressure-volume (PV) loop analysis obtained by conductance catheterization was performed at rest and during atrial pacing in patients with m...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis,
Volume 19, Issue 5, 3 1 2012, Pages 535-540
Long-term ongoing coagulopathy in premature infants with respiratory distress syndrome.
Buyukinan M, Yilmaz D, Yalaz M, Koroglu OA, Akisu M, Kavakli K, Kultursay N
The previously reported activated intravascular coagulation system in the acute phase of respiratory distress syndrome (RDS) has not been evaluated in the long term. We assessed the activities of coagulation system of a cohort of premature infants with RDS in comparison with healthy premature infants (HPIs), healthy mature infants (HMIs), and pediatric laboratory controls over a 6-month period. Cord and venous blood samples were taken at birth, at the first month and sixth month. Protein C (PC),...
Abstract
Cited 211 times since 2012 (16.1 per year)
source: EuropePMC
Basic research in cardiology,
Volume 107, Issue 4, 3 1 2012, Pages 270
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.
Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA, Sluijter JP
Accumulating evidence indicates that programmed necrosis plays a critical role in cell death during ischemia-reperfusion. Necrostatin-1 (Nec-1), a small molecule capable of inhibiting a key regulator of programmed necrosis (RIP1), was shown to prevent necrotic cell death in experimental models including cardiac ischemia. However, no functional follow-up was performed and the action of Nec-1 remains unclear. Here, we studied whether Nec-1 inhibits RIP1-dependent necrosis and leads to long-term im...
Abstract
Cited 3 times since 2012 (0.2 per year)
source: EuropePMC
The pharmacogenomics journal,
Volume 13, Issue 4, 1 1 2012, Pages 318-324
Added value of pharmacogenetic testing in predicting statin response: results from the REGRESS trial.
van der Baan FH, Knol MJ, Maitland-van der Zee AH, Regieli JJ, van Iperen EP, Egberts AC, Klungel OH, Grobbee DE, Jukema JW
It was investigated whether pharmacogenetic factors, both as single polymorphism and as gene-gene interactions, have an added value over non-genetic factors in predicting statin response. Five common polymorphisms were selected in apolipoprotein E, angiotensin-converting enzyme, hepatic lipase and toll-like receptor 4. Linear regression models were built and compared on R(2) to estimate the added value of single polymorphisms and gene-gene interactions. The selected polymorphisms and the gene-ge...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 197-201
Potential cardiovascular consequences of switching from atorvastatin to generic simvastatin in the Netherlands.
Liew D, Webb K, Meerding WJ, Buskens E, Jukema JW
Background: The statin authorisation form implemented in the Netherlands in January 2009 has led to significant switching of patients from atorvastatin to generic simvastatin, but often to less than equipotent doses. We sought to assess the potential consequences of this. Methods: A modelling analysis was undertaken using data from a pharmacy database covering the majority of drug prescriptions in the Netherlands. Recent meta-analyses provided data on the dose-specific, lipid-modifying potencies...
Abstract
Cited 26 times since 2012 (2 per year)
source: EuropePMC
Clinical science (London, England : 1979),
Volume 122, Issue 9, 1 1 2012, Pages 421-428
Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention study.
Meijer CA, Le Haen PA, van Dijk RA, Hira M, Hamming JF, van Bockel JH, Lindeman JH
Animal studies implicate the AP-1 (activator protein-1) pro-inflammatory pathway as a promising target in the treatment of atherosclerotic disease. It is, however, unclear whether these observations apply to human atherosclerosis. Therefore we evaluated the profile of AP-1 activation through histological analysis and tested the potential benefit of AP-1 inhibition in a clinical trial. AP-1 activation was quantified by phospho-c-Jun nuclear translocation (immunohistochemistry) on a biobank of aor...
Abstract
Cited 28 times since 2012 (2.1 per year)
source: EuropePMC
Pharmacogenomics,
Volume 13, Issue 7, 1 1 2012, Pages 831-840
Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.
Postmus I, Verschuren JJ, de Craen AJ, Slagboom PE, Westendorp RG, Jukema JW, Trompet S
Statins are the most commonly prescribed class of drug worldwide and therapy is highly effective in reducing low-density lipoprotein cholesterol levels and cardiovascular events. However, there is large variability in clinical response to statin treatment. Recent research provides evidence that genetic variation contributes to this variable response to statin treatment. Until recently, pharmacogenetic studies have used mainly candidate gene approaches to investigate these effects. Since candidat...
Abstract
Cited 28 times since 2012 (2.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 98, Issue 9, 1 1 2012, Pages 743-754
Transcatheter aortic valve implantation: implications of multimodality imaging in patient selection, procedural guidance, and outcomes.
Delgado V, Kapadia S, Schalij MJ, Schuijf JD, Tuzcu EM, Bax JJ
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 240-244
Einthoven dissertation prizes 2011.
van der Wall EE, Schalij MJ, Umans V, van Gilst WH
Abstract
Journal of the American College of Cardiology,
Volume 59, Issue 21, 1 1 2012, Pages e41
Quadruple valve replacement: visualization with 256-slice computed tomography.
Symersky P, Budde RP, Koolbergen DR, de Mol BA
Abstract
Cited 10 times since 2012 (0.8 per year)
source: Scopus
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 202-207
Preexisting heart failure is an underestimated risk factor in cardiac surgery.
Kortekaas KA, Lindeman JH, Versteegh MI, Stijnen T, Dion RA, Klautz RJ
Background: Heart failure is characterised as a strong risk factor for systemic failure after cardiac surgery. However, the impact has never been substantiated. Methods: Patients with heart failure (n = 48) - scheduled for elective ventricular reconstruction or external constraint device-were compared with a one-to-one matched control group of patients without heart failure undergoing cardiac surgery between 2006 and 2009. Results: As expected, patients with heart failure more frequently experie...
Abstract
Cited 39 times since 2012 (3 per year)
source: EuropePMC
Archives of orthopaedic and trauma surgery,
Volume 132, Issue 8, 24 4 2012, Pages 1191-1197
Contralateral hip fractures and other osteoporosis-related fractures in hip fracture patients: incidence and risk factors. An observational cohort study of 1,229 patients.
Vochteloo AJ, Borger van der Burg BL, Röling MA, van Leeuwen DH, van den Berg P, Niggebrugge AH, de Vries MR, Tuinebreijer WE, Bloem RM, Nelissen RG, Pilot P
Purpose: To report risk factors, 1-year and overall risk for a contralateral hip and other osteoporosis-related fractures in a hip fracture population. Methods: An observational study on 1,229 consecutive patients of 50 years and older, who sustained a hip fracture between January 2005 and June 2009. Fractures were scored retrospectively for 2005-2008 and prospectively for 2008-2009. Rates of a contralateral hip and other osteoporosis-related fractures were compared between patients with and wit...
Abstract
