7971 results
Cited 15 times since 2018 (2.1 per year)
source: EuropePMC
European radiology,
Volume 28, Issue 9, 6 1 2018, Pages 4027-4035
High spatial resolution free-breathing 3D late gadolinium enhancement cardiac magnetic resonance imaging in ischaemic and non-ischaemic cardiomyopathy: quantitative assessment of scar mass and image quality.
Bizino MB, Tao Q, Amersfoort J, Siebelink HJ, van den Bogaard PJ, van der Geest RJ, Lamb HJ
Purpose: To compare breath-hold (BH) with navigated free-breathing (FB) 3D late gadolinium enhancement cardiac MRI (LGE-CMR) MATERIALS AND METHODS: Fifty-one patients were retrospectively included (34 ischaemic cardiomyopathy, 14 non-ischaemic cardiomyopathy, three discarded). BH and FB 3D phase sensitive inversion recovery sequences were performed at 3T. FB datasets were reformatted into normal resolution (FB-NR, 1.46x1.46x10mm) and high resolution (FB-HR, isotropic 0.91-mm voxels). Scar mass,...
Abstract
Cited 103 times since 2018 (14.4 per year)
source: EuropePMC
The Journal of clinical investigation,
Volume 128, Issue 5, 3 1 2018, Pages 1837-1851
Mycobacterial growth inhibition is associated with trained innate immunity.
Joosten SA, van Meijgaarden KE, Arend SM, Prins C, Oftung F, Korsvold GE, Kik SV, Arts RJ, van Crevel R, Netea MG, Ottenhoff TH
The lack of defined correlates of protection hampers development of vaccines against tuberculosis (TB). In vitro mycobacterial outgrowth assays are thought to better capture the complexity of the human host/Mycobacterium tuberculosis (Mtb) interaction. Here, we used a mycobacterial growth inhibition assay (MGIA) based on peripheral blood mononuclear cells to investigate the capacity to control outgrowth of bacille Calmette-Guérin (BCG). Interestingly, strong control of BCG outgrowth was observed...
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 12, Issue 3, 3 1 2018, Pages 212-219
Diagnostic accuracy of semi-automatic quantitative metrics as an alternative to expert reading of CT myocardial perfusion in the CORE320 study.
Ostovaneh MR, Vavere AL, Mehra VC, Kofoed KF, Matheson MB, Arbab-Zadeh A, Fujisawa Y, Schuijf JD, Rochitte CE, Scholte AJ, Kitagawa K, Dewey M, Cox C, DiCarli MF, George RT, Lima JAC
Aims: To determine the diagnostic accuracy of semi-automatic quantitative metrics compared to expert reading for interpretation of computed tomography perfusion (CTP) imaging. Methods: The CORE320 multicenter diagnostic accuracy clinical study enrolled patients between 45 and 85 years of age who were clinically referred for invasive coronary angiography (ICA). Computed tomography angiography (CTA), CTP, single photon emission computed tomography (SPECT), and ICA images were interpreted manually...
Abstract
Cited 15 times since 2018 (2.1 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 106, Issue 2, 3 1 2018, Pages 412-420
National Comparison of Hospital Performances in Lung Cancer Surgery: The Role of Case Mix Adjustment.
Beck N, Hoeijmakers F, van der Willik EM, Heineman DJ, Braun J, Tollenaar RAEM, Schreurs WH, Wouters MWJM
Background: When comparing hospitals on outcome indicators, proper adjustment for case mix (a combination of patient and disease characteristics) is indispensable. This study examines the need for case mix adjustment in evaluating hospital outcomes for non-small cell lung cancer surgery. Methods: Data from the Dutch Lung Cancer Audit for Surgery were used to validate factors associated with postoperative 30-day mortality and complicated course with multivariable logistic regression models. Betwe...
Abstract
Cited 42 times since 2018 (5.9 per year)
source: EuropePMC
Clinical pharmacokinetics,
Volume 57, Issue 4, 1 1 2018, Pages 475-489
A Population Pharmacokinetic Model to Predict the Individual Starting Dose of Tacrolimus Following Pediatric Renal Transplantation.
Andrews LM, Hesselink DA, van Gelder T, Koch BCP, Cornelissen EAM, Brüggemann RJM, van Schaik RHN, de Wildt SN, Cransberg K, de Winter BCM
Background: Multiple clinical, demographic, and genetic factors affect the pharmacokinetics of tacrolimus in children, yet in daily practice, a uniform body-weight based starting dose is used. It can take weeks to reach the target tacrolimus pre-dose concentration. Objectives: The objectives of this study were to determine the pharmacokinetics of tacrolimus immediately after kidney transplantation and to find relevant parameters for dose individualization using a population pharmacokinetic analy...
Abstract
Cited 21 times since 2018 (2.9 per year)
source: EuropePMC
International journal of epidemiology,
Volume 47, Issue 2, 1 1 2018, Pages 396-396j
Cohort Profile: The Hoorn Studies.
Rutters F, Nijpels G, Elders P, Stehouwer CDA, van der Heijden AA, Groeneveld L, 't Hart LM, Dekker JM, Beulens JWJ
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Annals of translational medicine,
Volume 6, Issue 7, 1 1 2018, Pages 115
No association between systemic complement activation and intensive care unit-acquired weakness.
Witteveen E, Wieske L, de Beer FM, Juffermans NP, Verhamme C, Schultz MJ, van Schaik IN, Horn J, BASIC study group
Background: The main risk factors for intensive care unit-acquired weakness (ICU-AW) are sepsis, the systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction. These risk factors are associated with systemic complement activation. We hypothesized that critically ill patients who develop ICU-AW have increased systemic complement activation compared to critically ill patients who do not develop ICU-AW. Methods: Complement activation products C3b/c, C4b/c and C5a were measured i...
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 71, Issue 15, 1 1 2018, Pages 1661-1662
Machine Learning for Electrocardiographic Diagnosis of Left Ventricular Early Diastolic Dysfunction.
Bax JJ, van der Bijl P, Delgado V
Abstract
Cited 8 times since 2018 (1.1 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 11, Issue 4, 1 1 2018, Pages e007117
Cardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study.
Bonios MJ, Koliopoulou A, Wever-Pinzon O, Taleb I, Stehlik J, Xu W, Wever-Pinzon J, Catino A, Kfoury AG, Horne BD, Nativi-Nicolau J, Adamopoulos SN, Fang JC, Selzman CH, Bax JJ, Drakos SG
Background: Impaired qualitative and quantitative left ventricular (LV) rotational mechanics predict cardiac remodeling progression and prognosis after myocardial infarction. We investigated whether cardiac rotational mechanics can predict cardiac recovery in chronic advanced cardiomyopathy patients. Methods and results: Sixty-three patients with advanced and chronic dilated cardiomyopathy undergoing implantation of LV assist device (LVAD) were prospectively investigated using speckle tracking e...
Abstract
Cited 98 times since 2018 (13.7 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 14, 1 1 2018, Pages 1131-1143
2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia.
Landmesser U, Chapman MJ, Stock JK, Amarenco P, Belch JJF, Borén J, Farnier M, Ference BA, Gielen S, Graham I, Grobbee DE, Hovingh GK, Lüscher TF, Piepoli MF, Ray KK, Ray KK, Stroes ES, Wiklund O, Windecker S, Zamorano JL, Pinto F, Tokgözoglu L, Bax JJ, Catapano AL
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 26, Issue 4, 1 1 2018, Pages 566-572
Outcome reporting for surgical treatment of degenerative mitral valve disease: a systematic review and critical appraisal.
Tomšic A, Arabkhani B, Schoones JW, van Brakel TJ, Takkenberg JJM, Palmen M, Klautz RJM
Objectives: Standardized outcome reporting is of critical importance for performance monitoring, improvement of existing techniques and introduction of novel technologies. Whether outcome reporting for surgical treatment of degenerative mitral valve disease complies with the guidelines has not been assessed to date. Methods: A systematic review of PubMed, EMBASE, Web of Science and the Cochrane Library was conducted for articles published between 1 January 2009 and 7 March 2016. Inclusion criter...
Abstract
Cited 34 times since 2018 (4.7 per year)
source: EuropePMC
Endocrine reviews,
Volume 39, Issue 2, 1 1 2018, Pages 154-191
Diagnostic Utility of Molecular and Imaging Biomarkers in Cytological Indeterminate Thyroid Nodules.
de Koster EJ, de Geus-Oei LF, Dekkers OM, van Engen-van Grunsven I, Hamming J, Corssmit EPM, Morreau H, Schepers A, Smit J, Oyen WJG, Vriens D
Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned benign and malignant lesions, which are particularly difficult to differentiate on cytology alone. As ~25% of these nodules harbor malignancy, diagnostic hemithyroidectomy is still custom. However, advanced preoperative diagnostics are rapidly evolving.This review provides an overview of additional molecular and imaging diagnostics for indeterminate thyroid nodules in a preoperative clinical setting, includi...
Abstract
Cited 1 times since 2018 (0.1 per year)
source: EuropePMC
Journal of hypertension,
Volume 36, Issue 4, 1 1 2018, Pages 773-778
Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history.
Wijsman LW, Muller M, de Craen AJM, Jukema JW, Westendorp RGJ, Mooijaart SP
Background: In older age, a low DBP has been associated with increased risk of cardiovascular events, especially in frail older people. We tested the hypothesis that low DBP is associated with a high risk of cardiovascular events in people with a previous history of cardiovascular disease, as a proxy of vascular impairment. Methods: We included 5804 participants (mean age 75 years) from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) who as part of the trial were intensivel...
Abstract
Cited 10 times since 2018 (1.4 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 26, Issue 4, 1 1 2018, Pages 610-616
Early and late results of surgical treatment for isolated active native mitral valve infective endocarditis.
Tomšic A, Versteegh MIM, Ajmone Marsan N, van Brakel TJ, Klautz RJM, Palmen M
Objectives: Native mitral valve infective endocarditis (IE) is a complicated disease with high mortality and morbidity rates. Mitral valve repair (MVRep) is feasible when limited valve destruction is present. However, recurrent valve dysfunction and reintervention are common. Methods: Between January 2000 and March 2016, 83 patients underwent surgery for isolated active native mitral valve IE. We applied an early surgery, MVRep-oriented approach with progressive utilization of patch techniques t...
Abstract
Cited 7 times since 2018 (1 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 26, Issue 4, 1 1 2018, Pages 559-565
Mitral valve repair in Barlow's disease with bileaflet prolapse: the effect of annular stabilization on functional mitral valve leaflet prolapse.
Tomšic A, Hiemstra YL, Bissessar DD, van Brakel TJ, Versteegh MIM, Ajmone Marsan N, Klautz RJM, Palmen M
Objectives: Barlow's disease is the most severe form of degenerative mitral valve disease, commonly characterized by bileaflet prolapse. Abnormal mitral annular dynamics is typically present and results in functional prolapse of the mitral leaflets that may be addressed with annular stabilization alone. Methods: Between January 2001 and December 2015, 128 patients with Barlow's disease and bileaflet prolapse underwent valve repair. This included anterior mitral valve leaflet (AMVL) rep...
Abstract
Cited 32 times since 2018 (4.5 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 15, 1 1 2018, Pages 1308-1313
Inter-ethnic differences in valve morphology, valvular dysfunction, and aortopathy between Asian and European patients with bicuspid aortic valve.
Kong WKF, Regeer MV, Poh KK, Yip JW, van Rosendael PJ, Yeo TC, Tay E, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Background: Transcatheter aortic valve replacement (TAVR) has been shown safe and feasible in patients with bicuspid aortic valve (BAV) morphology. Evaluation of inter-ethnic differences in valve morphology and function and aortic root dimensions in patients with BAV is important for the worldwide spread of this therapy in this subgroup of patients. Comparisons between large European and Asian cohorts of patients with BAV have not been performed, and potential differences between populations may...
Abstract
Cited 58 times since 2018 (8.1 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 16, 1 1 2018, Pages 1416-1425
Left atrial function to identify patients with atrial fibrillation at high risk of stroke: new insights from a large registry.
Leung M, van Rosendael PJ, Abou R, Ajmone Marsan N, Leung DY, Delgado V, Bax JJ
Aims: Atrial fibrillation (AF) is an independent risk factor for ischaemic stroke. The CHA2DS2-VASc is the most widely used risk stratification model; however, echocardiographic refinement may be useful, particularly in low risk AF patients. The present study examined the association between advanced echocardiographic parameters and ischaemic stroke, independent of CHA2DS2-VASc score. Methods and results: One thousand, three hundred and sixty-one patients (mean age 65±12 years, 74% males) with f...
Abstract
Cited 54 times since 2018 (7.5 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 103, Issue 5, 30 5 2018, Pages 795-801
Pharmacogenetic Information in Clinical Guidelines: The European Perspective.
Swen JJ, Nijenhuis M, van Rhenen M, de Boer-Veger NJ, Buunk AM, Houwink EJF, Mulder H, Rongen GA, van Schaik RHN, van der Weide J, Wilffert B, Deneer VHM, Guchelaar HJ, Dutch Pharmacogenetics Working Group (DPWG) of the Royal Dutch Pharmacists Association (KNMP)
Surveys among pharmacists and physicians show that these healthcare professionals have successfully adopted the concept of pharmacogenomics (PGx).1-3 In addition, patients are willing to consent to participate in PGx implementation studies.4 However, the surveys also show that healthcare professionals do not frequently order or recommend a PGx test.1,2 Among others, a frequently perceived hurdle for clinical uptake of PGx is the availability of guidelines translating PGx test results into clinic...
Abstract
Cited 13 times since 2018 (1.8 per year)
source: EuropePMC
Heart rhythm,
Volume 15, Issue 10, 29 5 2018, Pages 1533-1539
Prognostic value of global longitudinal strain in heart failure patients treated with cardiac resynchronization therapy.
Khidir MJH, Abou R, Yilmaz D, Ajmone Marsan N, Delgado V, Bax JJ
Background: Myocardial fibrosis (macroscopic scar or diffuse reactive fibrosis) is one of the determinants of impaired left ventricular (LV) global longitudinal strain (GLS) in heart failure (HF) patients. Objective: The purpose of this study was to evaluate the prognostic value of LV GLS in HF patients treated with cardiac resynchronization therapy (CRT). Methods: The study included 829 HF patients (mean age 64.6 ± 10.4 years; 72% men) treated with CRT. Before CRT implantation, LV GLS was asses...
Abstract
Turkish journal of haematology : official journal of Turkish Society of Haematology,
Volume 35, Issue 2, 28 4 2018, Pages 122-128
Acute Traumatic Coagulopathy: The Value of Histone in Pediatric Trauma Patients.
Ulusoy E, Duman M, Çağlar A, Küme T, Er A, Akgül F, Çitlenbik H, Yılmaz D, Ören H
Objective: Acute traumatic coagulopathy occurs after trauma with impairment of hemostasis and activation of fibrinolysis. Some endogenous substances may play roles in this failure of the coagulation system. Extracellular histone is one such molecule that has recently attracted attention. This study investigated the association between plasma histone-complexed DNA (hcDNA) fragments and coagulation abnormalities in pediatric trauma patients. Materials and methods: This prospective case-control stu...
Abstract
