8684 results
Cited 126 times since 2017 (16.7 per year)
source: EuropePMC
Acta ophthalmologica,
Volume 96, Issue 1, 27 4 2017, Pages 63-68
Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System.
van der Heijden AA, Abramoff MD, Verbraak F, van Hecke MV, Liem A, Nijpels G
Purpose: To increase the efficiency of retinal image grading, algorithms for automated grading have been developed, such as the IDx-DR 2.0 device. We aimed to determine the ability of this device, incorporated in clinical work flow, to detect retinopathy in persons with type 2 diabetes. Methods: Retinal images of persons treated by the Hoorn Diabetes Care System (DCS) were graded by the IDx-DR device and independently by three retinal specialists using the International Clinical Diabetic Retinop...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
BMC public health,
Volume 17, Issue 1, 25 4 2017, Pages 900
Social-cognitive determinants of the tick check: a cross-sectional study on self-protective behavior in combatting Lyme disease.
van der Heijden A, Mulder BC, Poortvliet PM, van Vliet AJH
Background: Performing a tick check after visiting nature is considered the most important preventive measure to avoid contracting Lyme disease. Checking the body for ticks after visiting nature is the only measure that can fully guarantee whether one has been bitten by a tick and provides the opportunity to remove the tick as soon as possible, thereby greatly reducing the chance of contracting Lyme disease. However, compliance to performing the tick check is low. In addition, most previous stud...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 34, Issue 4, 24 4 2017, Pages 625-632
Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake.
Kuijpers D, van Dijk R, van Assen M, Kaandorp TAM, van Dijkman PRM, Vliegenthart R, van der Harst P, Oudkerk M
Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-mapping with SSO and splenic rest-stress T1-mapping in patients with and without recent coffee intake. We analyzed 344 consecutive patients suspected of myocardial ischemia with adenosine perfusion CMR...
Abstract
Cited 30 times since 2017 (4 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 31, Issue 4, 23 4 2017, Pages 505-514.e3
Feasibility, Accuracy, and Reproducibility of Aortic Annular and Root Sizing for Transcatheter Aortic Valve Replacement Using Novel Automated Three-Dimensional Echocardiographic Software: Comparison with Multi-Detector Row Computed Tomography.
Prihadi EA, van Rosendael PJ, Vollema EM, Bax JJ, Delgado V, Ajmone Marsan N
Background: In transcatheter aortic valve replacement (TAVR), multi-detector row computed tomography (MDCT) is currently the standard imaging modality for correct prosthesis sizing, despite risks of radiation and contrast-induced renal injury. Three-dimensional (3D) transesophageal echocardiography (TEE) has been proposed as a potential alternative imaging technique, and recently, automated 3D transesophageal echocardiographic software (Aortic Valve Navigator [AVN], an unreleased prototype from...
Abstract
Cited 23 times since 2017 (3.1 per year)
source: EuropePMC
Trials,
Volume 18, Issue 1, 23 4 2017, Pages 558
The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial.
Kingslake J, Dias R, Dawson GR, Simon J, Goodwin GM, Harmer CJ, Morriss R, Brown S, Guo B, Dourish CT, Ruhé HG, Lever AG, Veltman DJ, van Schaik A, Deckert J, Reif A, Stäblein M, Menke A, Gorwood P, Voegeli G, Pérez V, Browning M
Background: Antidepressant medication is commonly used to treat depression. However, many patients do not respond to the first medication prescribed and improvements in symptoms are generally only detectable by clinicians 4-6 weeks after the medication has been initiated. As a result, there is often a long delay between the decision to initiate an antidepressant medication and the identification of an effective treatment regimen. Previous work has demonstrated that antidepressant medications alt...
Abstract
Cited 56 times since 2017 (7.4 per year)
source: EuropePMC
European journal of preventive cardiology,
Volume 25, Issue 2, 22 4 2017, Pages 181-189
Age and gender differences in medical adherence after myocardial infarction: Women do not receive optimal treatment - The Netherlands claims database.
Eindhoven DC, Hilt AD, Zwaan TC, Schalij MJ, Borleffs CJW
Background Following myocardial infarction, medication is, besides lifestyle interventions, the cornerstone treatment to improve survival and minimize the occurrence of new cardiovascular events. Still, data on nationwide medication adherence are scarce. This study assesses medical adherence during one year following myocardial infarction, stratifying per type of infarct, age and gender. Design Retrospective cohort study. Methods In The Netherlands, all inhabitants are by law obliged to have hea...
Abstract
Cited 42 times since 2017 (5.6 per year)
source: EuropePMC
BMC genomics,
Volume 18, Issue 1, 21 3 2017, Pages 893
RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum.
Zhang X, de Maat V, Guzmán Prieto AM, Prajsnar TK, Bayjanov JR, de Been M, Rogers MRC, Bonten MJM, Mesnage S, Willems RJL, van Schaik W
Background: The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been characterized. Here, we identify genes that contribute to growth of E. faecium in human serum through transcriptome profiling (RNA-seq) and a high-throughput transposon mutant library sequencing approach (Tn-seq)...
Abstract
Cited 34 times since 2017 (4.5 per year)
source: EuropePMC
European journal of heart failure,
Volume 20, Issue 3, 21 3 2017, Pages 560-568
Prevalence of left ventricular systolic dysfunction in pre-dialysis and dialysis patients with preserved left ventricular ejection fraction.
Hensen LCR, Goossens K, Delgado V, Abou R, Rotmans JI, Jukema JW, Bax JJ
Aims: Patients with chronic kidney disease (CKD) have an excess of cardiovascular morbidity and mortality, with heart failure (HF) being particularly frequent. Reduced left ventricular ejection fraction (LVEF) defines left ventricular (LV) systolic dysfunction and is associated with poor prognosis. However, CKD patients may have HF symptoms with preserved LVEF. In this subgroup of patients, two-dimensional speckle tracking echocardiography can detect LV systolic dysfunction by analysing LV myoca...
Abstract
Cited 8 times since 2017 (1.1 per year)
source: EuropePMC
Diabetologia,
Volume 61, Issue 1, 20 3 2017, Pages 138-146
HbA<sub>1c</sub> is associated with altered expression in blood of cell cycle- and immune response-related genes.
Slieker RC, van der Heijden AAWA, van Leeuwen N, Mei H, Nijpels G, Beulens JWJ, 't Hart LM
Aims/hypothesis: Individuals with type 2 diabetes are heterogeneous in their glycaemic control as tracked by blood HbA1c levels. Here, we investigated the extent to which gene expression levels in blood reflect current and future HbA1c levels. Methods: HbA1c levels at baseline and 1 and 2 year follow-up were compared with gene expression levels in 391 individuals with type 2 diabetes from the Hoorn Diabetes Care System Cohort (15,564 genes, RNA sequencing). The functions of associated baseline g...
Abstract
Cited 11 times since 2017 (1.5 per year)
source: EuropePMC
Heart rhythm,
Volume 15, Issue 3, 20 3 2017, Pages 386-392
Implantable cardioverter-defibrillator therapy in hypertrophic cardiomyopathy: A SIMPLE substudy.
Vamos M, Healey JS, Wang J, Connolly SJ, Mabo P, Van Erven L, Kautzner J, Glikson M, Neuzner J, O'Hara G, Vinolas X, Gadler F, Hohnloser SH
Background: Patients with hypertrophic cardiomyopathy (HCM) are considered to be at high risk for elevated defibrillation thresholds, periprocedural complications, and failed appropriate shocks. Objective: The purpose of this study was to determine the value of defibrillation testing (DT) in HCM patients undergoing implantable cardioverter-defibrillator (ICD) insertion. Methods: Defibrillation thresholds, perioperative complications, and long-term outcomes were compared between patients with HCM...
Abstract
Cited 10 times since 2017 (1.3 per year)
source: EuropePMC
Rheumatology international,
Volume 38, Issue 3, 18 3 2017, Pages 443-453
Physical activity in patients with systemic sclerosis.
Liem SIE, Meessen JMTA, Wolterbeek R, Ajmone Marsan N, Ninaber MK, Vliet Vlieland TPM, de Vries-Bouwstra JK
Objectives: To compare self-reported levels of physical activity (PA) of systemic sclerosis (SSc) patients with the general population. To evaluate in SSc patients factors associated with PA levels and needs and preferences regarding PA. Methods: Fifty nine SSc patients completed the Short QUestionnaire to ASsess Health-Enhancing PA. The proportion of patients meeting the Dutch Recommendation for PA (= moderate PA for 30 min on ≥ 5 days/week) and total minutes of PA per week were calculated and...
Abstract
Cited 18 times since 2017 (2.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 38, Issue 1, 16 3 2017, Pages 186-194
Statins Promote Cardiac Infarct Healing by Modulating Endothelial Barrier Function Revealed by Contrast-Enhanced Magnetic Resonance Imaging.
Leenders GJ, Smeets MB, van den Boomen M, Berben M, Nabben M, van Strijp D, Strijkers GJ, Prompers JJ, Arslan F, Nicolay K, Vandoorne K
Objective: The endothelium has a crucial role in wound healing, acting as a barrier to control transit of leukocytes. Endothelial barrier function is impaired in atherosclerosis preceding myocardial infarction (MI). Besides lowering lipids, statins modulate endothelial function. Here, we noninvasively tested whether statins affect permeability at the inflammatory (day 3) and the reparative (day 7) phase of infarct healing post-MI using contrast-enhanced cardiac magnetic resonance imaging (MRI)....
Abstract
Cited 24 times since 2017 (3.2 per year)
source: EuropePMC
Scientific reports,
Volume 7, Issue 1, 13 2 2017, Pages 15464
The effects of sociability on exploratory tendency and innovation repertoires in wild Sumatran and Bornean orangutans.
Schuppli C, Forss S, Meulman E, Atmoko SU, van Noordwijk M, van Schaik C
It has been hypothesized that opportunities for social learning affect the size and complexity of the adult skill set of birds and mammals, their learning ability, and thus ultimately also their innovation frequency. To test these predictions we compared rates of social learning, rates of independent exploration (independent learning) and innovation repertoires between individuals of a highly sociable population of Pongo abelii at Suaq Balimbing and a less sociable population of Pongo pygmaeus w...
Abstract
Cited 365 times since 2017 (48.2 per year)
source: EuropePMC
Circulation,
Volume 137, Issue 4, 13 2 2017, Pages 338-350
Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).
Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS
Background: The PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitor evolocumab reduced low-density lipoprotein cholesterol and cardiovascular events in the FOURIER trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk). We investigated the efficacy and safety of evolocumab in patients with peripheral artery disease (PAD) as well as the effect on major adverse limb events. Methods: FOURIER was a randomized trial of evolocumab versus place...
Abstract
Cited 6 times since 2017 (0.8 per year)
source: EuropePMC
BMJ open,
Volume 7, Issue 11, 12 2 2017, Pages e018833
Barriers and facilitators to learn and improve through morbidity and mortality conferences: a qualitative study.
de Vos MS, Hamming JF, Marang-van de Mheen PJ
Objectives: To explore barriers and facilitators to successful morbidity and mortality conferences (M&M), driving learning and improvement. Design: This is a qualitative study with semistructured interviews. Inductive, thematic content analysis was used to identify barriers and facilitators, which were structured across a pre-existing framework for change in healthcare. Setting: Dutch academic surgical department with a long tradition of M&M. Participants: An interview sample of surgeons...
Abstract
Cited 166 times since 2017 (21.9 per year)
source: EuropePMC
Scientific reports,
Volume 7, Issue 1, 10 2 2017, Pages 15364
Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction.
Matamoros S, van Hattem JM, Arcilla MS, Willemse N, Melles DC, Penders J, Vinh TN, Thi Hoa N, Bootsma MCJ, van Genderen PJ, Goorhuis A, Grobusch M, Molhoek N, Oude Lashof AML, Stobberingh EE, Verbrugh HA, de Jong MD, Schultsz C
To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying the mcr-1 gene. After a systematic review of the literature we included 65 E. coli whole genome sequences (WGS), adding 6 recently sequenced travel related isolates, and 312 MLST profiles. We included 219 MGEs described in 7 Enterobacteriaceae species isolated from human, animal and environmental samples. Despite a hig...
Abstract
Cited 3 times since 2017 (0.4 per year)
source: EuropePMC
BMC veterinary research,
Volume 13, Issue 1, 9 2 2017, Pages 324
Quantitative and qualitative aspects of standing-up behavior and the prevalence of osteochondrosis in Warmblood foals on different farms: could there be a link?
van Grevenhof EM, Gezelle Meerburg ARD, van Dierendonck MC, van den Belt AJM, van Schaik B, Meeus P, Back W
Background: Osteochondrosis (OC) is a common, clinically important joint disorder in which endochondral ossification is focally disturbed. Reduced blood supply to growing cartilage is considered an important cause of the condition, which has both genetic and environmental origins. Housing conditions can influence cartilage injury through peak-pressure changes during limb sliding. Additionally, circulatory perturbation can cause the avascular necrosis of cartilage. In this study, we evaluated the...
Abstract
Cited 134 times since 2017 (17.7 per year)
source: EuropePMC
The Lancet. Neurology,
Volume 17, Issue 1, 6 1 2017, Pages 35-46
Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial.
van Schaik IN, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Mielke O, Durn BL, Cornblath DR, Merkies ISJ, PATH study group
Background: Approximately two-thirds of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) need long-term intravenous immunoglobulin. Subcutaneous immunoglobulin (SCIg) is an alternative option for immunoglobulin delivery, but has not previously been investigated in a large trial of CIDP. The PATH study compared relapse rates in patients given SCIg versus placebo. Methods: Between March 12, 2012, and Sept 20, 2016, we studied patients from 69 neuromuscular centres in North Am...
Abstract
Cited 9 times since 2017 (1.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 25, Issue 1, 6 1 2017, Pages 39-52
Myocardial perfusion imaging: Lessons learned and work to be done-update.
Iskandrian AE, Dilsizian V, Garcia EV, Beanlands RS, Cerqueira M, Soman P, Berman DS, Cuocolo A, Einstein AJ, Morgan CJ, Hage FG, Schelbert HR, Bax JJ, Wu JC, Shaw LJ, Sadeghi MM, Tamaki N, Kaufmann PA, Gropler R, Dorbala S, Van Decker W
As the second term of our commitment to Journal begins, we, the editors, would like to reflect on a few topics that have relevance today. These include prognostication and paradigm shifts; Serial testing: How to handle data? Is the change in perfusion predictive of outcome and which one? Ischemia-guided therapy: fractional flow reserve vs perfusion vs myocardial blood flow; positron emission tomography (PET) imaging using Rubidium-82 vs N-13 ammonia vs F-18 Flurpiridaz; How to differentiate micr...
Abstract
Cited 8 times since 2017 (1.1 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 4, Issue 2, 6 1 2017, Pages 221-227
The Impact of Atrial Fibrillation Clinical Subtype on Mortality.
Leung M, van Rosendael PJ, Abou R, Ajmone Marsan N, Leung DY, Delgado V, Bax JJ
Objectives: This study sought to investigate the prognostic implications of the clinical subtype of atrial fibrillation (AF): paroxysmal or persistent. Background: Underlying structural abnormalities of the left atrium may be responsible for the initial clinical presentation of AF in either paroxysmal or persistent form, yet the prognostic implications of the clinical subtype on presentation are unknown. Methods: Over a median of 7 years, 1,773 patients (age 64 ± 12 years, 74% males) with nonval...
Abstract
