8684 results
Cited 77 times since 2017 (10.1 per year)
source: EuropePMC
Current biology : CB,
Volume 27, Issue 22, 2 1 2017, Pages 3487-3498.e10
Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species.
Nater A, Mattle-Greminger MP, Nurcahyo A, Nowak MG, de Manuel M, Desai T, Groves C, Pybus M, Sonay TB, Roos C, Lameira AR, Wich SA, Askew J, Davila-Ross M, Fredriksson G, de Valles G, Casals F, Prado-Martinez J, Goossens B, Verschoor EJ, Warren KS, Singleton I, Marques DA, Pamungkas J, Perwitasari-Farajallah D, Rianti P, Tuuga A, Gut IG, Gut M, Orozco-terWengel P, van Schaik CP, Bertranpetit J, Anisimova M, Scally A, Marques-Bonet T, Meijaard E, Krützen M
Six extant species of non-human great apes are currently recognized: Sumatran and Bornean orangutans, eastern and western gorillas, and chimpanzees and bonobos [1]. However, large gaps remain in our knowledge of fine-scale variation in hominoid morphology, behavior, and genetics, and aspects of great ape taxonomy remain in flux. This is particularly true for orangutans (genus: Pongo), the only Asian great apes and phylogenetically our most distant relatives among extant hominids [1]. Designation...
Abstract
Cited 4 times since 2017 (0.5 per year)
source: EuropePMC
Journal of clinical lipidology,
Volume 12, Issue 1, 2 1 2017, Pages 137-144.e1
Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.
Christen T, Trompet S, Noordam R, Blauw LL, Gast KB, Rensen PCN, Willems van Dijk K, Rosendaal FR, de Mutsert R, Jukema JW, NEO study
Background: Several trials to prevent cardiovascular disease by inhibiting cholesteryl ester transfer protein (CETP) have failed, except Randomized EValuation of the Effects of Anacetrapib through Lipid-modification. Thus far, it is unclear to what extent CETP is causally related to measures of atherosclerosis. Objective: The aim of the article was to study the causal relationship between genetically determined CETP concentration and carotid intima-media thickness (cIMT) in a population-based co...
Abstract
Cited 3 times since 2017 (0.4 per year)
source: EuropePMC
Lung cancer (Amsterdam, Netherlands),
Volume 114, 2 1 2017, Pages 50-55
Esophageal ultrasound (EUS) assessment of T4 status in NSCLC patients.
Kuijvenhoven JC, Crombag L, Breen DP, van den Berk I, Versteegh MIM, Braun J, Winkelman TA, van Boven W, Bonta PI, Rabe KF, Annema JT
Background: Mediastinal and central large vessels (T4) invasion by lung cancer is often difficult to assess preoperatively due to the limited accuracy of computed tomography (CT) scan of the chest. Esophageal ultrasound (EUS) can visualize the relationship of para-esophageally located lung tumors to surrounding mediastinal structures. Aim: To assess the value of EUS for detecting mediastinal invasion (T4) of centrally located lung tumors. Methods: Patients who underwent EUS for the diagnosis and...
Abstract
Cited 21 times since 2017 (2.8 per year)
source: EuropePMC
Current biology : CB,
Volume 27, Issue 22, 1 1 2017, Pages 3576-3577
Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species.
Nater A, Mattle-Greminger MP, Nurcahyo A, Nowak MG, de Manuel M, Desai T, Groves C, Pybus M, Sonay TB, Roos C, Lameira AR, Wich SA, Askew J, Davila-Ross M, Fredriksson G, de Valles G, Casals F, Prado-Martinez J, Goossens B, Verschoor EJ, Warren KS, Singleton I, Marques DA, Pamungkas J, Perwitasari-Farajallah D, Rianti P, Tuuga A, Gut IG, Gut M, Orozco-terWengel P, van Schaik CP, Bertranpetit J, Anisimova M, Scally A, Marques-Bonet T, Meijaard E, Krützen M
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Clinical microbiology reviews,
Volume 31, Issue 1, 1 1 2017, Pages e00082-17
Correction for Quainoo et al., "Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis".
Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL
Abstract
Cited 46 times since 2017 (6.1 per year)
source: EuropePMC
Annals of surgery,
Volume 266, Issue 5, 1 1 2017, Pages 898-904
Textbook Outcome: A Composite Measure for Quality of Elective Aneurysm Surgery.
Karthaus EG, Lijftogt N, Busweiler LAD, Elsman BHP, Wouters MWJM, Vahl AC, Hamming JF, Dutch Society of Vascular Surgery, the Steering Committee of the Dutch Surgical Aneurysm Audit, the Dutch Institute for Clinical Auditing
Objective: To investigate a new composite quality measurement, which comprises a desirable outcome for elective aneurysm surgery, called "Textbook Outcome" (TO). Background: Single-quality indicators in vascular surgery are often not distinctive and insufficiently reflect the quality of care. Methods: All patients undergoing elective abdominal aortic aneurysm repair, registered in the Dutch Surgical Aneurysm Audit between 2014 and 2015 were included. TO was defined as the percentage of...
Abstract
Cited 11 times since 2017 (1.4 per year)
source: EuropePMC
JCO precision oncology,
Volume 1, 1 1 2017, Pages 1-10
Treatment Algorithm for Homozygous or Compound Heterozygous <i>DPYD</i> Variant Allele Carriers With Low-Dose Capecitabine.
Henricks LM, Kienhuis E, de Man FM, van der Veldt AAM, Hamberg P, van Kuilenburg ABP, van Schaik RHN, Lunenburg CATC, Guchelaar HJ, Schellens JHM, Mathijssen RHJ
Abstract
Medical education,
Volume 51, Issue 11, 1 1 2017, Pages 1181-1182
Working with students with disabilities: simulation-based faculty development.
Meeks L, Richards A, Chang A, van Schaik S
Abstract
Anatolian journal of cardiology,
Volume 18, Issue 5, 1 1 2017, Pages E9-E10
Giant right coronary artery aneurysm mimicking sinus Valsalva aneurysm of the aorta.
Sucu N, Bilgiç A, Yılmaz D, Öztaş A
Abstract
Clinical genetics,
Volume 92, Issue 5, 1 1 2017, Pages 565
Response to Ciuculete et al.
Smit RAJ, le Cessie S, Jukema JW, Trompet S
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 70, Issue 19, 1 1 2017, Pages 2459-2460
Left Main Extrinsic Compression in Pulmonary Arterial Hypertension: From Identification to Percutaneous Coronary Intervention Optimization.
Montero Cabezas JM, Nuche Berenguer J, Velázquez Martín MT, Escribano Subías P
Abstract
Cited 15 times since 2017 (2 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 18, Issue 11, 1 1 2017, Pages 1206-1213
Frequency and angiographic characteristics of coronary microvascular dysfunction in stable angina: a hybrid imaging study.
Stenström I, Maaniitty T, Uusitalo V, Pietilä M, Ukkonen H, Kajander S, Mäki M, Bax JJ, Knuuti J, Saraste A
Aims: Coronary microvascular dysfunction (CMD) can cause angina in the absence of obstructive coronary artery disease (CAD). We studied the frequency and angiographic characteristics of CMD in symptomatic patients with suspected stable CAD and identified CMD as diffusely abnormal coronary vasodilator capacity by positron emission tomography (PET) perfusion imaging. Methods and results: We recruited prospectively 189 patients with intermediate pre-test probability of CAD who underwent coronary co...
Abstract
Cited 35 times since 2017 (4.6 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 10, Issue 11, 1 1 2017, Pages e005591
Localized Optogenetic Targeting of Rotors in Atrial Cardiomyocyte Monolayers.
Feola I, Volkers L, Majumder R, Teplenin A, Schalij MJ, Panfilov AV, de Vries AAF, Pijnappels DA
Background: Recently, a new ablation strategy for atrial fibrillation has emerged, which involves the identification of rotors (ie, local drivers) followed by the localized targeting of their core region by ablation. However, this concept has been subject to debate because the mode of arrhythmia termination remains poorly understood, as dedicated models and research tools are lacking. We took a unique optogenetic approach to induce and locally target a rotor in atrial monolayers. Methods and res...
Abstract
Cited 91 times since 2017 (12 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 66, Issue 5, 1 1 2017, Pages 1379-1389
Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms.
van Schaik TG, Yeung KK, Verhagen HJ, de Bruin JL, van Sambeek MRHM, Balm R, Zeebregts CJ, van Herwaarden JA, Blankensteijn JD, DREAM trial participants
Objective: Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required to demonstrate the cumulative negative impact on survival of higher reintervention rates associated with endovascular repair. Methods: We updated the results of the Dutch Randomized Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled tria...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Substance use & misuse,
Volume 53, Issue 6, 30 5 2017, Pages 921-930
Effectiveness of Fresh Start: A Randomized Study of a School-Based Program to Retain a Negative Attitude Toward Substance Use in Secondary School Freshmen.
Onrust SA, van der Heijden A, Zschämisch AL, Speetjens PAM
Background: The transition to secondary school is linked to more positive attitudes toward substance use, which prelude the moment of first use. Fresh Start is a school-based prevention program for secondary school freshmen (12-13 years old) to retain negative attitudes. Objectives: This study evaluates the effectiveness of Fresh Start on the attitudes toward smoking, alcohol use, and cannabis use, and on multiple secondary outcome measures. In addition, the effect of timing of the program withi...
Abstract
Cited 14 times since 2017 (1.8 per year)
source: EuropePMC
Cardiovascular and interventional radiology,
Volume 41, Issue 2, 30 5 2017, Pages 323-329
Evaluation of CT Angiography Image Quality Acquired with Single-Energy Metal Artifact Reduction (SEMAR) Algorithm in Patients After Complex Endovascular Aortic Repair.
Ragusi MAAD, van der Meer RW, Joemai RMS, van Schaik J, van Rijswijk CSP
Purpose: To evaluate the value of single-energy metal artifact reduction (SEMAR) algorithm on image quality in patients after complex endovascular aortic repair (EVAR) with fenestrated and branched devices. Methods: Routine follow-up computed tomography angiography (CTA) examinations were performed between February 2016 and May 2017 in 18 patients who underwent a complex EVAR procedure at our institution. Objective analysis was performed by measuring the standard deviation (SD) of attenuation (H...
Abstract
Cited 382 times since 2017 (50.2 per year)
source: EuropePMC
Nature genetics,
Volume 49, Issue 12, 30 5 2017, Pages 1758-1766
Exome-wide association study of plasma lipids in >300,000 individuals.
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrieres J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Jarvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein cholesterol (LDL-C), and/or triglycerides (TG). At two loci (JAK2 and A1CF), experimental analysis in mice showed lipid changes consistent with the human data. We also found that: (i) beta-thalass...
Abstract
Cited 12 times since 2017 (1.6 per year)
source: EuropePMC
Pregnancy hypertension,
Volume 11, 28 4 2017, Pages 129-135
Assessment of novel cardiovascular biomarkers in women with a history of recurrent miscarriage.
Wagner MM, Jukema JW, Hermes W, le Cessie S, de Groot CJM, Bakker JA, van Lith JMM, Bloemenkamp KWM
Objectives: A history of recurrent miscarriage is associated with future cardiovascular disease. The aim of this study was to determine novel cardiovascular biomarkers in women with a history of recurrent miscarriage as this might lead to a better understanding of the association. Study design: Women who visited the recurrent miscarriage clinic at Leiden University Medical Centre (between 2000 and 2010), and had three consecutive miscarriages ≤30 years were invited to participate in this follow-...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
BMC musculoskeletal disorders,
Volume 18, Issue 1, 27 4 2017, Pages 424
Design of the SALT Osteoporosis Study: a randomised pragmatic trial, to study a primary care screening and treatment program for the prevention of fractures in women aged 65 years or older.
Elders PJM, Merlijn T, Swart KMA, van Hout W, van der Zwaard BC, Niemeijer C, Heymans MW, van der Heijden AA, Rutters F, van der Horst HE, Lips P, Netelenbos JC, van Schoor NM
Background: Several drugs have become available for the treatment of osteoporosis. However, screening and treatment of patients with a high fracture risk is currently not recommended in the Netherlands, because the effectiveness of bone sparing drugs has not been demonstrated in the general primary care population. Here we describe the design of the SALT Osteoporosis study, which aims to examine whether the screening and treatment of older, female patients in primary care can reduce fractures, i...
Abstract
Cited 3 times since 2017 (0.4 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 34, Issue 4, 27 4 2017, Pages 495-502
In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR-OCT co-registration study.
Pyxaras SA, Adriaenssens T, Barbato E, Ughi GJ, Di Serafino L, De Vroey F, Toth G, Tu S, Reiber JHC, Bax JJ, Wijns W
We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with drug-eluting stent...
Abstract
