8684 results
Cited 67 times since 2017 (8.8 per year)
source: EuropePMC
Diabetes care,
Volume 41, Issue 1, 26 4 2017, Pages 112-119
Hyperbaric Oxygen Therapy in the Treatment of Ischemic Lower- Extremity Ulcers in Patients With Diabetes: Results of the DAMO<sub>2</sub>CLES Multicenter Randomized Clinical Trial.
Santema KTB, Stoekenbroek RM, Koelemay MJW, Reekers JA, van Dortmont LMC, Oomen A, Smeets L, Wever JJ, Legemate DA, Ubbink DT, DAMO2CLES Study Group
Objective: Conflicting evidence exists on the effects of hyperbaric oxygen therapy (HBOT) in the treatment of chronic ischemic leg ulcers. The aim of this trial was to investigate whether additional HBOT would benefit patients with diabetes and ischemic leg ulcers. Research design and methods: Patients with diabetes with an ischemic wound (n = 120) were randomized to standard care (SC) without or with HBOT (SC+HBOT). Primary outcomes were limb salvage and wound healing after 12 months, as well a...
Abstract
Cited 5 times since 2017 (0.7 per year)
source: EuropePMC
Disability and health journal,
Volume 11, Issue 2, 23 4 2017, Pages 267-273
Experiences of persons with spinal cord injury undertaking a physical activity programme as part of the SCIPA 'Full-On' randomized controlled trial.
Calder A, Nunnerley J, Mulligan H, Ahmad Ali N, Kensington G, McVicar T, van Schaik O
Background: For individuals with spinal cord injury the long term benefits of physical activity are well documented, however the majority of this population report inactivity secondary to participatory barriers. Research investigating physically intensive exercise programs for people with spinal cord injury is limited, with even less attention paid to the experience of the participants. Objective: To explore the experiences of persons with spinal cord injury of their participation in the New Zea...
Abstract
Cited 14 times since 2017 (1.8 per year)
source: EuropePMC
European journal of heart failure,
Volume 20, Issue 4, 23 4 2017, Pages 803-806
The first titin (c.59926 + 1G > A) founder mutation associated with dilated cardiomyopathy.
Hoorntje ET, van Spaendonck-Zwarts KY, Te Rijdt WP, Boven L, Vink A, van der Smagt JJ, Asselbergs FW, van Wijngaarden J, Hennekam EA, Pinto YM, Lekanne Deprez RH, Barge-Schaapveld DQCM, Bootsma M, Regieli J, Hoedemaekers YM, Jongbloed JDH, van den Berg MP, van Tintelen JP
Abstract
Cited 8 times since 2017 (1 per year)
source: EuropePMC
Chemistry & biodiversity,
Volume 14, Issue 11, 21 3 2017
Highly Enantioselective Production of Chiral Secondary Alcohols Using Lactobacillus paracasei BD101 as a New Whole Cell Biocatalyst and Evaluation of Their Antimicrobial Effects.
Yılmaz D, Şahin E, Dertli E
Chiral secondary alcohols are valuable intermediates for many important enantiopure pharmaceuticals and biologically active molecules. In this work, we studied asymmetric reduction of aromatic ketones to produce the corresponding chiral secondary alcohols using lactic acid bacteria (LAB) as new biocatalysts. Seven LAB strains were screened for their ability to reduce acetophenones to their corresponding alcohols. Among these strains, Lactobacillus paracasei BD101 was found to be the most success...
Abstract
Cited 100 times since 2017 (13.1 per year)
source: EuropePMC
Nature communications,
Volume 8, Issue 1, 13 2 2017, Pages 910
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bert
Genomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of 606,059 parents' survival, we discover two regions associated with longevity (HLA-DQA1/DRB1 and LPA). We also validate previous suggestions that APOE, CHRNA3/5, CDKN2A/B, SH2B3 and FOXO3A influence longevity. Next we show that giving up smoking, educational attainment, openness to new experience and high-density lipoprotein (HDL) cholesterol level...
Abstract
Cited 25 times since 2017 (3.3 per year)
source: EuropePMC
PloS one,
Volume 12, Issue 10, 10 2 2017, Pages e0185820
The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development.
de Jong RCM, Ewing MM, de Vries MR, Karper JC, Bastiaansen AJNM, Peters HAB, Baghana F, van den Elsen PJ, Gongora C, Jukema JW, Quax PHA
Objective: Genetic P300/CBP-associated factor (PCAF) variation affects restenosis-risk in patients. PCAF has lysine acetyltransferase activity and promotes nuclear factor kappa-beta (NFκB)-mediated inflammation, which drives post-interventional intimal hyperplasia development. We studied the contributing role of PCAF in post-interventional intimal hyperplasia. Methods and results: PCAF contribution to inflammation and intimal hyperplasia was assessed in leukocytes, macrophages and vascular smoot...
Abstract
Cited 12 times since 2017 (1.6 per year)
source: EuropePMC
BMC cardiovascular disorders,
Volume 17, Issue 1, 10 2 2017, Pages 259
Feasibility and safety of early discharge after transfemoral transcatheter aortic valve implantation - rationale and design of the FAST-TAVI registry.
Barbanti M, Baan J, Spence MS, Iacovelli F, Martinelli GL, Saia F, Bortone AS, van der Kley F, Muir DF, Densem CG, Vis M, van Mourik MS, Seilerova L, Lüske CM, Bramlage P, Tamburino C
Background: There is an increasing trend towards shorter hospital stays after transcatheter aortic valve implantation (TAVI), in particular for patients undergoing the procedure via transfemoral (TF) access. Preliminary data suggest that there exists a population of patients that can be discharged safely very early after TF-TAVI. However, current evidence is limited to few retrospective studies, encompassing relatively small sample sizes. Methods: The Feasibility And Safety of early discharge af...
Abstract
Cited 13 times since 2017 (1.7 per year)
source: Scopus
The American journal of cardiology,
Volume 121, Issue 1, 10 2 2017, Pages 86-93
Influence of the Quantity of Aortic Valve Calcium on the Agreement Between Automated 3-Dimensional Transesophageal Echocardiography and Multidetector Row Computed Tomography for Aortic Annulus Sizing.
Podlesnikar T, Prihadi EA, van Rosendael PJ, Vollema EM, van der Kley F, de Weger A, Ajmone Marsan N, Naji F, Fras Z, Bax JJ, Delgado V
Accurate aortic annulus sizing is key for selection of appropriate transcatheter aortic valve implantation (TAVI) prosthesis size. The present study compared novel automated 3-dimensional (3D) transesophageal echocardiography (TEE) software and multidetector row computed tomography (MDCT) for aortic annulus sizing and investigated the influence of the quantity of aortic valve calcium (AVC) on the selection of TAVI prosthesis size. A total of 83 patients with severe aortic stenosis undergoing TAV...
Abstract
Neuropsychiatric disease and treatment,
Volume 13, 9 2 2017, Pages 2581-2584
Sporadic hyperekplexia due to self-limiting brainstem encephalopathy.
Yilmaz D, Cengiz B
Hyperekplexia is a rare movement disorder characterized by pathologically exaggerated response to unexpected stimuli. It is differentiated from the normal startle reflex by its lower threshold, higher intensity, and resistance to habituation. Many of the acquired hyperekplexias result from brainstem involvement such as encephalitis, infarct, hemorrhage, pontocerebellar hypoplasia and medullary compression. This case report depicts a rare manifestation of hyperekplexia. The unusual aspect of this...
Abstract
Cited 6 times since 2017 (0.8 per year)
source: EuropePMC
New media & society,
Volume 20, Issue 7, 8 2 2017, Pages 2582-2603
A phased framework for long-term user acceptance of interactive technology in domestic environments.
de Graaf MM, Ben Allouch S, van Dijk JA
The temporal dimension of acceptance is under-researched in technology acceptance research. Yet, people's perceptions on technology use may change over time when gaining user experiences. Our 6-month home study deploying an interactive robot provides insight into the long-term use of use interactive technology in a domestic environment. We present a phased framework for the acceptance of interactive technology in domestic environments. Based on 97 interviews obtained from 21 participants li...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
Journal of neurology, neurosurgery, and psychiatry,
Volume 89, Issue 3, 6 1 2017, Pages 256-262
Quality of life in inflammatory neuropathies: the IN-QoL.
Draak THP, Faber CG, Merkies ISJ, PeriNomS study Group
Background: No consensus exists which quality of life (QoL) measure should be used in patients with inflammatory neuropathies. Moreover, most QoL measures are ordinal-based scales with their known deficiencies. Objectives: To establish a new disease-specific interval-based QoL questionnaire in inflammatory neuropathies (IN-QoL) using the Rasch model and evaluate its scientific properties (validity, reliability and responsiveness). Methods: 264 patients with inflammatory neuropathies completed si...
Abstract
Cited 18 times since 2017 (2.3 per year)
source: EuropePMC
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology,
Volume 125, Issue 1, 4 1 2017, Pages 55-61
Different manifestation of irradiation induced coronary artery disease detected with coronary computed tomography compared with matched non-irradiated controls.
van Rosendael AR, Daniëls LA, Dimitriu-Leen AC, Smit JM, van Rosendael PJ, Schalij MJ, Bax JJ, Scholte AJHA
Background and purpose: Patients who received chest irradiation for treatment of a malignancy are at increased risk for the development of coronary artery atherosclerosis. Little is known about the anatomical coronary artery plaque characteristics of irradiation induced coronary artery disease (CAD). This study aimed to evaluate potential differences in the presence, extent, severity, composition and location of CAD in patients treated with mediastinal irradiation compared with non-irradiated co...
Abstract
Cited 2 times since 2017 (0.3 per year)
source: EuropePMC
Biomedical engineering online,
Volume 16, Issue 1, 3 1 2017, Pages 118
Low-power transcutaneous current stimulator for wearable applications.
Karpul D, Cohen GK, Gargiulo GD, van Schaik A, McIntyre S, Breen PP
Background: Peripheral neuropathic desensitization associated with aging, diabetes, alcoholism and HIV/AIDS, affects tens of millions of people worldwide, and there is little or no treatment available to improve sensory function. Recent studies that apply imperceptible continuous vibration or electrical stimulation have shown promise in improving sensitivity in both diseased and healthy participants. This class of interventions only has an effect during application, necessitating the design of a...
Abstract
Cited 13 times since 2017 (1.7 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 52, Issue 4, 1 1 2017, Pages 832
Corrigendum to '2017 ESC/EACTS Guidelines for the management of valvular heart disease' [Eur J Cardiothorac Surg 2017;52:616-664].
Falk V, Baumgartner H, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Muñoz DR, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL, Roffi M, Alfieri O, Agewall S, Ahlsson A, Barbato E, Bueno H, Collet JP, Coman IM, Czerny M, Delgado V, Fitzsimons D, Folliguet T, Gaemperli O, Habib G, Harringer W, Haude M, Hindricks G, Katus HA, Knuuti J, Kolh P, Leclercq C, McDonagh TA, Piepoli MF, Pierard LA, Ponikowski P, Rosano GMC, Ruschitzka F, Shlyakhto E, Simpson IA, Sousa-Uva M, Stepinska J, Tarantini G, Tchétché D, Aboyans V
Abstract
Cited 266 times since 2017 (34.6 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 52, Issue 4, 1 1 2017, Pages 616-664
2017 ESC/EACTS Guidelines for the management of valvular heart disease.
Falk V, Baumgartner H, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Muñoz DR, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL, ESC Scientific Document Group
Abstract
Cited 2 times since 2017 (0.3 per year)
source: EuropePMC
Circulation,
Volume 136, Issue 17, 1 1 2017, Pages 1659-1661
ESC Congress 2017 in Barcelona: Where the World of Cardiology Came Together.
Bax JJ, Achenbach S
Abstract
Cited 4 times since 2017 (0.5 per year)
source: EuropePMC
Orthopedics,
Volume 40, Issue 5, 1 1 2017, Pages e868-e875
Vitamin D Use and Health Outcomes After Surgery for Hip Fracture.
Sprague S, Slobogean GP, Bogoch E, Petrisor B, Garibaldi A, O'Hara N, Bhandari M, FAITH Investigators
Daily administration of vitamin D is important for maintaining bone homeostasis. The orthopedic community has shown increased interest in vitamin D supplementation and patient outcomes after fracture. The current study used data from a large hip fracture trial to determine the proportion of patients who consistently used vitamin D after hip fracture surgery and to determine whether supplementation was associated with improved health-related quality of life and reduced reoperation rates. The FAIT...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 38, 1 1 2017, Pages 2913
MitraClip improves mitral valve geometry in complex organic mitral regurgitation: insights from three-dimensional-echocardiography.
Debonnaire P, van der Kley F, Ajmone Marsan N, Delgado V
Abstract
Cited 14 times since 2017 (1.8 per year)
source: EuropePMC
Clinical pharmacokinetics,
Volume 56, Issue 10, 1 1 2017, Pages 1231-1244
Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach.
Lammers LA, Achterbergh R, van Schaik RHN, Romijn JA, Mathôt RAA
Background and objective: Short-term fasting can alter drug exposure but it is unknown whether this is an effect of altered oral bioavailability and/or systemic clearance. Therefore, the aim of our study was to assess the effect of short-term fasting on oral bioavailability and systemic clearance of different drugs. Methods: In a randomized, controlled, crossover trial, 12 healthy subjects received a single administration of a cytochrome P450 (CYP) probe cocktail, consisting of caffeine (CYP1A2)...
Abstract
Cited 225 times since 2017 (29.3 per year)
source: EuropePMC
Clinical microbiology reviews,
Volume 30, Issue 4, 1 1 2017, Pages 1015-1063
Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis.
Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU) patients are particularly susceptible to nosocomial infections due to indwelling devices such as intravascular catheters, drains, and intratracheal tubes for mechanical ventilation. The increased vulnerability of infected ICU patients demonstrates the importance of effective outbreak management protocols to be in place. Understanding the t...
Abstract
