8684 results
Cited 24 times since 2017 (3.1 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 67, Issue 6, 11 2 2017, Pages 1891-1900.e4
Adventitial adipogenic degeneration is an unidentified contributor to aortic wall weakening in the abdominal aortic aneurysm.
Doderer SA, Gäbel G, Kokje VBC, Northoff BH, Holdt LM, Hamming JF, Lindeman JHN
Objective: The processes driving human abdominal aortic aneurysm (AAA) progression are not fully understood. Although antiinflammatory and proteolytic strategies effectively quench aneurysm progression in preclinical models, so far all clinical interventions failed. These observations hint at an incomplete understanding of the processes involved in AAA progression and rupture. Interestingly, strong clinical and molecular associations exist between popliteal artery aneurysms (PAAs) and AAAs; howe...
Abstract
Cited 4 times since 2017 (0.5 per year)
source: EuropePMC
European journal of heart failure,
Volume 19, Issue 12, 7 1 2017, Pages 1732-1735
Risk stratification of Asian patients with heart failure and reduced ejection fraction: the effectiveness of the Echo Heart Failure Score.
Bosch L, Carluccio E, Coiro S, Gong L, Sim D, Yeo D, Jaufeerally F, Leong KTG, Ong HY, Pin NT, Richards AM, Arslan F, Ling LH, Lam CSP, Ambrosio G
Abstract
Cited 173 times since 2017 (22.3 per year)
source: EuropePMC
Nature genetics,
Volume 49, Issue 10, 4 1 2017, Pages 1450-1457
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
Zhao W, Rasheed A, Tikkanen E, Lee JJ, Butterworth AS, Howson JMM, Assimes TL, Chowdhury R, Orho-Melander M, Damrauer S, Small A, Asma S, Imamura M, Yamauch T, Chambers JC, Chen P, Sapkota BR, Shah N, Jabeen S, Surendran P, Lu Y, Zhang W, Imran A, Abbas S, Majeed F, Trindade K, Qamar N, Mallick NH, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Rasheed SZ, Memon FU, Mehmood K, Ahmed N, Qureshi IH, Tanveer-Us-Salam, Iqbal W, Malik U, Mehra N, Kuo JZ, Sheu WH, Guo X, Hsiung CA, Juang JJ, Taylor KD, Hung YJ, Lee WJ, Quertermous T, Lee IT, Hsu CC, Bottinger EP, Ralhan S, Teo YY, Wang TD, Alam DS, Di Angelantonio E, Epstein S, Nielsen SF, Nordestgaard BG, Tybjaerg-Hansen A, Young R, CHD Exome+ Consortium, Benn M, Frikke-Schmidt R, Kamstrup PR, EPIC-CVD Consortium, EPIC-Interact Consortium, Michigan Biobank, Jukema JW, Sattar N, Smit R, Chung RH, Liang KW, Anand S, Sanghera DK, Ripatti S, Loos RJF, Kooner JS, Tai ES, Rotter JI, Chen YI, Frossard P, Maeda S, Kadowaki T, Reilly M, Pare G, Melander O, Salomaa V, Rader DJ, Da
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D and 1 locus for CHD, including a new T2D association at a missense variant in HLA-DRB5 (odds ratio (OR) = 1.29). We show that genetically mediated increase in T2D risk also confers higher CHD risk. J...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 70, Issue 13, 1 1 2017, Pages 1681-1682
Patients With an ICD Remain at Risk for Painful Shocks in Last Moments of Life.
Yilmaz D, van der Heijden AC, Thijssen J, Schalij MJ, van Erven L
Abstract
Cited 2684 times since 2017 (346 per year)
source: EuropePMC
European heart journal,
Volume 38, Issue 36, 1 1 2017, Pages 2739-2791
2017 ESC/EACTS Guidelines for the management of valvular heart disease.
Baumgartner H, Falk V, Bax JJ, De Bonis M, Hamm C, Holm PJ, Iung B, Lancellotti P, Lansac E, Rodriguez Muñoz D, Rosenhek R, Sjögren J, Tornos Mas P, Vahanian A, Walther T, Wendler O, Windecker S, Zamorano JL, ESC Scientific Document Group
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 52, Issue 3, 1 1 2017, Pages 418-424
Standards defining a 'Heart Valve Centre': ESC Working Group on Valvular Heart Disease and European Association for Cardiothoracic Surgery Viewpoint.
Chambers JB, Prendergast B, Iung B, Rosenhek R, Zamorano JL, Piérard LA, Modine T, Falk V, Kappetein AP, Pibarot P, Sundt T, Baumgartner H, Bax JJ, Lancellotti P
Abstract
Cited 19 times since 2017 (2.4 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 52, Issue 3, 1 1 2017, Pages 425-431
Safety, effectiveness and haemodynamic performance of a new stented aortic valve bioprosthesis.
Klautz RJM, Kappetein AP, Lange R, Dagenais F, Labrousse L, Bapat V, Moront M, Misfeld M, Zeng C, Sabik Iii JF, PERIGON Investigators
Objectives: We assessed the safety, effectiveness and haemodynamic performance of a new bovine stented aortic valve bioprosthesis (Avalus™). Methods: The PERIGON Pivotal Trial is a prospective, non-randomized, multicentre study. Subjects had symptomatic moderate or severe aortic stenosis or chronic, severe aortic regurgitation. Death, valve-related adverse events (AEs), functional recovery and haemodynamic performance were assessed at discharge, 3-6 months and 1 year. The primary analysis compar...
Abstract
Cited 11 times since 2017 (1.4 per year)
source: EuropePMC
Journal of applied oral science : revista FOB,
Volume 25, Issue 5, 1 1 2017, Pages 515-522
Effects of Syzygium aromaticum, Cinnamomum zeylanicum, and Salvia triloba extracts on proliferation and differentiation of dental pulp stem cells.
Mendi A, Yağci BG, Kiziloğlu M, Saraç N, Yilmaz D, Uğur A, Uçkan D
Introduction: Hypersensitivity, local irritative and cytotoxic effects are known for the chemical components of Syzygium aromaticum and Cinnamomum zeylanicum contained in dental materials. However, there is no intimate data in dentistry using the whole extracts of these plants and introducing new ones. Salvia triloba is a well-known anti-inflammatory plant that correspondingly could be used in several dental traumas. Objectives: We aimed to show and compare the effect of S. aromaticum, C. zeylan...
Abstract
Cited 6 times since 2017 (0.8 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 18, Issue 9, 1 1 2017, Pages 1041-1048
Three-dimensional transoesophageal echocardiography of the aortic valve and root: changes in aortic root dilation and aortic regurgitation.
Regeer MV, Kamperidis V, Versteegh MIM, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Aims: It has been hypothesized that in response to dilation of the aortic root, the aortic valve cusps may remodel to prevent aortic regurgitation (AR). The aim of the present study was to evaluate the association between aortic cusp dimensions and aortic root geometry. Methods and results: Three-dimensional transoesophageal echocardiography was performed in 40 patients with aortic root dilation (mean age 57 ± 12 years, 75% men, 35% bicuspid aortic valve) and 20 controls with a normal aortic roo...
Abstract
Cited 18 times since 2017 (2.3 per year)
source: EuropePMC
Current treatment options in cardiovascular medicine,
Volume 19, Issue 9, 1 1 2017, Pages 71
Current Challenges in Translating Tissue-Engineered Heart Valves.
Stassen OMJA, Muylaert DEP, Bouten CVC, Hjortnaes J
Opinion statement: Heart valve disease is a major health burden, treated by either valve repair or valve replacement, depending on the affected valve. Nearly 300,000 valve replacements are performed worldwide per year. Valve replacement is lifesaving, but not without complications. The in situ tissue-engineered heart valve is a promising alternative to current treatments, but the translation of this novel technology to the clinic still faces several challenges. These challenges originate from th...
Abstract
Cited 35 times since 2017 (4.5 per year)
source: EuropePMC
Pharmacogenetics and genomics,
Volume 27, Issue 9, 1 1 2017, Pages 313-322
The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.
Lloberas N, Elens L, Llaudó I, Padullés A, van Gelder T, Hesselink DA, Colom H, Andreu F, Torras J, Bestard O, Cruzado JM, Gil-Vernet S, van Schaik R, Grinyó JM
Introduction: Tacrolimus (Tac) has a narrow therapeutic window and shows large between-patient pharmacokinetic variability. As a result, over-immunosuppression and under-immunosuppression are frequently encountered in daily clinical practice. Unraveling the impact of genetic polymorphisms on Tac pharmacokinetics may help to refine therapy. In this study, the associations of single-nucleotide polymorphisms (SNPs) in drug-metabolizing enzymes (CYP3A) with Tac pharmacokinetics were investigated in...
Abstract
Cited 6 times since 2017 (0.8 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 22, Issue 3, 1 1 2017, Pages 213-218
Drug-induced cutaneous lupus erythematosus after immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy: a case series.
Adrichem ME, Starink MV, van Leeuwen EMM, Kramer C, van Schaik IN, Eftimov F
We describe six patients with cutaneous lupus erythematosus (cLE) during immunoglobulin G (IgG) treatment. Five patients were diagnosed with chronic inflammatory demyelinating polyneuropathy (CIDP) and one patient with possible CIDP. Five patients received intravenous immunoglobulin (IVIg) and one patient received subcutaneous immunoglobulin (SCIg). Skin lesions were systematically assessed by a dermatologist including skin biopsies. Patients showed disseminated erythematous plaques on several p...
Abstract
Cited 17 times since 2017 (2.2 per year)
source: EuropePMC
Acta orthopaedica Belgica,
Volume 83, Issue 3, 1 1 2017, Pages 341-350
Custom-made triflanged acetabular components in the treatment of major acetabular defects. Short-term results and clinical experience.
Myncke I, van Schaik D, Scheerlinck T
We report on the Belgian experience with the aMace® custom-made triflange acetabular component in revision total hip arthroplasty between September 2009 and November 2014. We focused on (1) the complexity of the preoperative planning and reimbursement procedure; (2) the surgical problems and operative experience; and (3) the early outcome. We collected 20 patients' reviews and 22 surgeons' reviews, with a mean follow-up of 25 months. The preoperative planning and reimbursement procedur...
Abstract
Cited 2 times since 2017 (0.3 per year)
source: EuropePMC
Journal of immunology (Baltimore, Md. : 1950),
Volume 199, Issue 5, 1 1 2017, Pages 1534-1541
Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. <i>Nature</i>. 1998. 395: 462-469.
Sayos J, Wu C, Morra M, Wang N, Zhang X, Allen D, van Schaik S, Notarangelo L, Geha R, Roncarolo MG, Oettgen H, De Vries JE, Aversa G, Terhorst C
Abstract
Cited 12 times since 2017 (1.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 18, Issue 9, 1 1 2017, Pages 969-977
Impact of computed tomography myocardial perfusion following computed tomography coronary angiography on downstream referral for invasive coronary angiography, revascularization and, outcome at 12 months.
van Rosendael AR, Dimitriu-Leen AC, de Graaf MA, van Zwet EW, Jukema JW, Bax JJ, Kroft LJ, Scholte AJ
Aims: The aim of this study was to assess the impact of adding stress computed tomography (CT) myocardial perfusion (CTP) to coronary CT angiography (CTA) on downstream referral for invasive coronary angiography (ICA), revascularization, and outcome in patients presenting with new-onset chest pain. Methods and results: Three hundred and eighty-four patients were referred for cardiac CT. Patients with lesions ≥50% stenosis underwent subsequently stress CTP. Perfusion scans were considered abnorma...
Abstract
Cited 59 times since 2017 (7.6 per year)
source: EuropePMC
Disease models & mechanisms,
Volume 10, Issue 9, 1 1 2017, Pages 1039-1059
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.
Brandão KO, Tabel VA, Atsma DE, Mummery CL, Davis RP
It is now a decade since human induced pluripotent stem cells (hiPSCs) were first described. The reprogramming of adult somatic cells to a pluripotent state has become a robust technology that has revolutionised our ability to study human diseases. Crucially, these cells capture all the genetic aspects of the patient from which they were derived. Combined with advances in generating the different cell types present in the human heart, this has opened up new avenues to study cardiac disease in hu...
Abstract
Cited 14 times since 2017 (1.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 12, 1 1 2017, Pages 675-681
A Dutch MYH7 founder mutation, p.(Asn1918Lys), is associated with early onset cardiomyopathy and congenital heart defects.
van der Linde IHM, Hiemstra YL, Bökenkamp R, van Mil AM, Breuning MH, Ruivenkamp C, Ten Broeke SW, Veldkamp RF, van Waning JI, van Slegtenhorst MA, van Spaendonck-Zwarts KY, Lekanne Deprez RH, Herkert JC, Boven L, van der Zwaag PA, Jongbloed JDH, Bootsma M, Barge-Schaapveld DQCM
Background: Mutations in the myosin heavy chain 7 (MYH7) gene commonly cause cardiomyopathy but are less frequently associated with congenital heart defects. Methods: In this study, we describe a mutation in the MYH7 gene, c. 5754C > G; p. (Asn1918Lys), present in 15 probands and 65 family members. Results: Of the 80 carriers (age range 0-88 years), 46 (57.5%) had cardiomyopathy (mainly dilated cardiomyopathy (DCM)) and seven (8.8%) had a congenital heart defect. Childhood onset of cardiomyop...
Abstract
Cited 22 times since 2017 (2.8 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 10, Issue 9, 1 1 2017, Pages e005987
Bicuspid Aortic Valve: What to Image in Patients Considered for Transcatheter Aortic Valve Replacement?
Kong WKF, Delgado V, Bax JJ
Abstract
JAMA cardiology,
Volume 2, Issue 9, 1 1 2017, Pages 1047-1048
Bicuspid Aortopathy-Reply.
Delgado V, Kong WKF, Bax JJ
Abstract
Cited 3 times since 2017 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 9, 1 1 2017, Pages 490-497
Classical determinants of coronary artery disease as predictors of complexity of coronary lesions, assessed with the SYNTAX score.
Montero-Cabezas JM, Karalis I, Wolterbeek R, Kraaijeveld AO, Hoefer IE, Pasterkamp G, Pijls NH, Doevendans PA, Walterberger J, Kuiper J, van Zonneveld AJ, Jukema JW
Background: We need new biomarkers that can predict cardiovascular disease to improve both diagnosis and therapeutic strategies. The CIRCULATING CELLS study was designed to study the role of several cellular mediators of atherosclerosis as biomarkers of coronary artery disease (CAD). An objective and reproducible method for the quantification of CAD extension is required to establish relationships with these potential biomarkers. We sought to analyse the correlation of the SYNTAX score with know...
Abstract
