9618 results
Turkish journal of medical sciences,
Volume 55, Issue 1, 13 2 2024, Pages 237-241
Inflammatory changes in the prepuce and clinical findings according to the stages of phimosis.
Doğan G, Yilmaz D, Ipek H, Metin M, Kahraman H, Afşarlar ÇE
Background/aim: Circumcision refers to the surgical removal of all or part of the prepuce. Circumcision is commonly performed on males in childhood to prevent urinary tract infections and for religious reasons. This study was designed to investigate the inflammatory processes in the prepuce according to the degree of phimosis in patients who underwent circumcision. Materials and methods: We conducted a prospective study on 173 male children under the age of 18 who underwent circumcision between...
Abstract
The American journal of cardiology,
Volume 236, 12 2 2024, Pages 49-55
Sex Differences in a Real-World Registry Examining Coronary Lithotripsy for Calcified Lesions.
van Oort MJH, Oliveri F, Ibtihal AA, Bingen BO, Claessen BEPM, Dimitriu-Leen AC, Vossenberg TN, Kefer J, Girgis H, van der Kley F, Jukema JW, Montero-Cabezas JM
Intravascular lithotripsy (IVL) has been established as a safe and effective treatment for coronary artery calcification (CAC). This study aimed to evaluate sex-related differences in the treatment with IVL in a real-world, all-comers international registry. Patients who underwent IVL between May 2019 and February 2024 were enrolled from the BENELUX-IVL registry. Patients were divided into men and women groups. Efficacy end points included device success (delivery of the IVL balloon across the t...
Abstract
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
8 2 2024, Pages 15266028241296490
Diagnostic Value of Maximal Systolic Acceleration Measurements in the Follow-up of Complex Endovascular Aortic Repair: Illustration of a Concept.
Willems SA, Brouwers JJWM, Hamming JF, Hinnen JW, van der Vorst JR, van Schaik J
Purpose: After complex endovascular aortic repair (cEVAR), long-term surveillance is advocated to monitor for potential (stent-related) complications. Although various imaging modalities are used, computed tomography angiography remains the standard in current clinical practice worldwide. However, radiopaque markers can cause metal artifacts and scattering, hampering assessment of patency of side branches. The maximal systolic acceleration (ACCmax) is a relatively new duplex ultrasound (DUS) par...
Abstract
Cited 2 times since 2024 (2.6 per year)
source: EuropePMC
Nature communications,
Volume 15, Issue 1, 7 1 2024, Pages 9652
Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice.
Kip P, Sluiter TJ, MacArthur MR, Tao M, Kruit N, Mitchell SJ, Jung J, Kooijman S, Gorham J, Seidman JG, Quax PHA, Decano JL, Aikawa M, Ozaki CK, Mitchell JR, de Vries MR
Short-term preoperative methionine restriction (MetR) is a promising translatable strategy to mitigate surgical injury response. However, its application to improve post-interventional vascular remodeling remains underexplored. Here we find that MetR protects from arterial intimal hyperplasia in a focal stenosis model and pathologic vascular remodeling following vein graft surgery in male mice. RNA sequencing reveals that MetR enhances browning in arterial (thoracic aorta) perivascular adipose t...
Abstract
Cited 11 times since 2024 (14.1 per year)
source: EuropePMC
Science advances,
Volume 10, Issue 45, 6 1 2024, Pages eadp1764
High-speed odor sensing using miniaturized electronic nose.
Dennler N, Drix D, Warner TPA, Rastogi S, Casa CD, Ackels T, Schaefer AT, van Schaik A, Schmuker M
Animals have evolved to rapidly detect and recognize brief and intermittent encounters with odor packages, exhibiting recognition capabilities within milliseconds. Artificial olfaction has faced challenges in achieving comparable results-existing solutions are either slow; or bulky, expensive, and power-intensive-limiting applicability in real-world scenarios for mobile robotics. Here, we introduce a miniaturized high-speed electronic nose, characterized by high-bandwidth sensor readouts, tightl...
Abstract
Journal of cardiology,
Volume 86, Issue 1, 6 1 2024, Pages 102
Authors' reply.
Tomšič A, Palmen M
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
Journal of pediatric hematology/oncology,
Volume 47, Issue 1, 6 1 2024, Pages 19-30
Retrospective Comparison of Targeted Anticancer Drugs Predicted by the CNS-TAP Tool Versus Those Selected by a Molecularly Driven Tumor Board in Children With DIPG.
Roberts HJ, Ravi K, Marini BL, Schepers A, Kline C, Kilburn L, Prados M, Byron SA, Sturza J, Mueller S, Koschmann C, Franson AT
The recent trial Pediatric Neuro-Oncology Consortium 003 (PNOC003) utilized a molecular tumor board to recommend personalized treatment regimens based on tumor sequencing results in children with DIPG. We separately developed the Central Nervous System Targeted Agent Prediction (CNS-TAP) tool, which numerically scores targeted anticancer agents using preclinical, clinical, and patient-specific data. We hypothesized that highly scored agents from CNS-TAP would overlap with the PNOC003 tumor board...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
International journal of cancer,
Volume 156, Issue 8, 5 1 2024, Pages 1529-1540
Smoking behavior and the risks of tumor recurrence and progression in patients with non-muscle-invasive bladder cancer.
Kiebach J, Beeren I, Aben KKH, Witjes JA, van der Heijden AG, Kiemeney LALM, Vrieling A
Studies on the relationship of cigarette smoking with the risks of recurrence and progression of non-muscle-invasive bladder cancer (NMIBC) are inconsistent and prospective data are scarce. Therefore, we aimed to assess the association of smoking behavior with risks of NMIBC recurrence and progression. We used data of the prospective multi-center cohort study UroLife, including 1495 patients with NMIBC who reported information on smoking at 6 weeks post-diagnosis (baseline; reflecting present an...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
Nature communications,
Volume 15, Issue 1, 2 1 2024, Pages 9483
Longitudinal genomics reveals carbapenem-resistant Acinetobacter baumannii population changes with emergence of highly resistant ST164 clone.
Liu H, Moran RA, Doughty EL, Hua X, Snaith AE, Zhang L, Chen X, Guo F, van Schaik W, McNally A, Yu Y
Carbapenem-resistant Acinetobacter baumannii (CRAB) is a persistent nosocomial pathogen that poses a significant threat to global public health, particularly in intensive care units (ICUs). Here we report a three-month longitudinal genomic surveillance study conducted in a Hangzhou ICU in 2021. This followed a three-month study conducted in the same ICU in 2019, and infection prevention and control (IPC) interventions targeting patients, staff and the ICU environment. Most A. baumannii isolated...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
The journal of applied laboratory medicine,
Volume 9, Issue 6, 1 1 2024, Pages 949-963
Quality Assurance for Multiplex Quantitative Clinical Chemistry Proteomics in Large Clinical Trials.
Reijnders E, Romijn FPHTM, Arslan F, Georges JJJ, Pieterse MM, Schipper ER, Didden-Buitendijk S, Martherus-Bultman MC, Smit NPM, Diederiks NM, Treep MM, Jukema JW, Cobbaert CM, Ruhaak LR
Background: To evaluate the clinical performance and effectiveness of a multiplex apolipoprotein panel in the context of cardiovascular precision diagnostics, clinical samples of patients with recent acute coronary syndrome in the ODYSSEY OUTCOMES trial were measured by quantitative clinical chemistry proteomics (qCCP). The ISO15189-accredited laboratory setting, including the total testing process (TTP), served as a foundation for this study. Consequently, tailored quality assurance measures ne...
Abstract
Cited 5 times since 2024 (6.3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 26, Issue 11, 1 1 2024, Pages euae243
2024 updated European Heart Rhythm Association core curriculum for physicians and allied professionals: a statement of the European Heart Rhythm Association of the European Society of Cardiology.
Trines SA, Moore P, Burri H, Gonçalves Nunes S, Massoullié G, Merino JL, Paton MF, Porta-Sánchez A, Sommer P, Steven D, Whittaker-Axon S, Yorgun H, Arribas F, Claude Deharo J, Steffel J, Wolpert C
Heart rhythm management is a continuously evolving sub-speciality of cardiology. Every year, many physicians and allied professionals (APs) start and complete their training in cardiac implantable electronic devices (CIEDs) or electrophysiology (EP) across the European Heart Rhythm Association (EHRA) member countries. While this training ideally ends with an EHRA certification, the description of the learning pathway (what, how, when, and where) through an EHRA core curriculum is also a prerequi...
Abstract
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
Volume 29, Issue 47, 1 1 2024
Agile, on-demand wastewater surveillance of virus infections to support pandemic and outbreak response in Rotterdam-Rijnmond, the Netherlands, 2020 to 2022.
Besijn E, Whelan J, Bijkerk P, Sips GJ, Langeveld J, Izquierdo-Lara RW, van Baarle E, Schilperoort R, Koopmans MPG, de Graaf M, Medema G, Fanoy E
BackgroundWastewater surveillance may support early and comprehensive detection of infectious diseases' community transmission, particularly in settings where other health surveillance systems provide biased or limited information. Amid the SARS-CoV-2 pandemic, deploying passive samplers to monitor targeted populations gained importance. Evaluation of the added public health value of this approach in the field can support its broader adoption.AimWe aimed to assess the feasibility and utilit...
Abstract
Communications medicine,
Volume 4, Issue 1, 1 1 2024, Pages 223
Regional mechanical dyssynchrony and shortened systole are present in people with Takotsubo syndrome.
Reil JC, Sequeira V, Reil GH, Steendijk P, Maack C, Fink T, Rawish E, Eitel I, Stiermaier T
Background: Takotsubo syndrome is characterized by transient regional systolic dysfunction, left ventricular (LV) dilatation, and edema, often occurring without obstructive coronary artery disease. The mechanisms underlying this stress-induced condition, especially the role of mechanical dyssynchrony in affecting systolic function, remain poorly understood. Methods: In our study, we evaluated global LV function and mechanical dyssynchrony in 24 Takotsubo patients compared to 20 controls by analy...
Abstract
Cited 4 times since 2024 (5 per year)
source: EuropePMC
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
Volume 39, Issue 12, 1 1 2024, Pages 2048-2057
Long-term renal and cardiovascular risks of tacrolimus in patients with lupus nephritis.
van Schaik M, Bredewold OW, Priester M, Michels WM, Rabelink TJ, Rotmans JI, Teng YKO
Background: Despite continuous advancement, treatment of lupus nephritis (LN) remains challenging. Recent guidelines now include a regimen incorporating tacrolimus as a first-line treatment option. Even though tacrolimus is effective in combination with mycophenolate and corticosteroids, concerns remain regarding long-term use, given its association with increased cardiovascular risks including nephrotoxicity, hypertension, dyslipidemia and hyperglycemia in kidney transplant recipients. However,...
Abstract
Microbial genomics,
Volume 10, Issue 11, 1 1 2024
Longitudinal genomic surveillance of a UK intensive care unit shows a lack of patient colonisation by multi-drug-resistant Gram-negative bacterial pathogens.
Snaith AE, Moran RA, Hall RJ, Casey A, Ratcliffe L, van Schaik W, Whitehouse T, McNally A
Vulnerable patients in an intensive care unit (ICU) setting are at high risk of infection from bacteria including gut-colonising Escherichia coli and Klebsiella species. Complex ICU procedures often depend on successful antimicrobial treatment, underscoring the importance of understanding the extent of patient colonisation by multi-drug-resistant organisms (MDROs) in large UK ICUs. Previous work on ICUs globally uncovered high rates of colonisation by transmission of MDROs, but the situation in...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
Human reproduction (Oxford, England),
Volume 39, Issue 11, 1 1 2024, Pages 2423-2433
The impact of maternal vulnerability on stress biomarkers and first-trimester growth: the Rotterdam Periconceptional Cohort (Predict Study).
Van Zundert SKM, Van Rossem L, Mirzaian M, Willemsen SP, Voskamp LW, Bastiaansen WAP, Nikpayam D, Griffioen PH, Schilleman WF, Koning AHJ, Van Den Berg SAA, Rousian M, Van Schaik RHN, Steegers-Theunissen RPM
Study question: Is the degree of maternal vulnerability positively associated with stress biomarkers (stress hormones, C-reactive protein, tryptophan metabolites, and one-carbon metabolites), and does long-term exposure to stress hormones reduce first-trimester growth? Summary answer: The maternal vulnerability risk score is positively associated with concentrations of hair cortisol and cortisone and negatively with tryptophan, while higher hair cortisol concentrations are associated with reduce...
Abstract
Cited 14 times since 2024 (17.6 per year)
source: EuropePMC
European heart journal,
Volume 45, Issue 42, 1 1 2024, Pages 4512-4522
Benefit of isolated surgical valve repair or replacement for functional tricuspid regurgitation and long-term outcomes stratified by the TRI-SCORE.
Dreyfus J, Juarez-Casso F, Sala A, Carnero-Alcazar M, Eixerés-Esteve A, Bohbot Y, Bazire B, Flagiello M, Riant E, Mbaki Y, Tomasi J, Senage T, Rahmouni El Idrissi K, Coisne A, Eyharts D, Doguet F, Viau F, Eggenspieler F, Heuts S, Sardari Nia P, Heitzinger G, Galloo X, Ajmone Marsan N, Benfari G, Badano L, Muraru D, Maisano F, Topilsky Y, Michelena H, Enriquez-Sarano M, Bax J, Bartko P, Selton-Suty C, Habib G, Lavie-Badie Y, Modine T, Chan V, Le Tourneau T, Donal E, Lim P, Radu C, Bernick J, Wells GA, Tribouilloy C, Iung B, Obadia JF, De Bonis M, Crestanello J, Messika-Zeitoun D
Background and aims: Severe tricuspid regurgitation is associated with increased mortality rates, but benefit of its correction and ideal timing are not clearly determined. This study aimed to identify patient subsets who might benefit from the surgery. Methods: In TRIGISTRY, an international cohort study of consecutive patients with severe isolated functional tricuspid regurgitation (33 centres, 10 countries), survival rates up to 10 years were compared between patients who underwent isolated t...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 66, Issue 6, 1 1 2024, Pages ezae426
Learning curve of robotic mitral repair: prospective two-centre study of proficiency and clinical outcomes.
Sandoval E, Bhoera RA, Tomšič A, Morales-Rey I, García-Álvarez A, Palmen M, Pereda D
Objectives: Robotic-assisted mitral valve repair surgery has a steep learning curve, and it is not clear whether previous experience in minimally invasive mitral valve surgery (MIMVS) facilitates this process. We aimed to investigate the initial experience of 2 cardiac centres starting their robotic programmes, evaluating the impact of previous MIMVS experience. Methods: Retrospective analysis was performed for the 1st consecutive cases operated due to severe degenerative mitral valve regurgitat...
Abstract
Cited 2 times since 2024 (2.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 25, Issue 12, 1 1 2024, Pages 1721-1733
Association between echocardiography-derived haemodynamic force parameters and left ventricular reverse remodelling after cardiac resynchronization therapy.
Laenens D, van der Bijl P, Galloo X, Rossi AC, Tonti G, Reiber JHC, Pedrizzetti G, Ajmone Marsan N, Bax JJ
Aims: Cardiac resynchronization therapy (CRT) may induce left ventricular (LV) reverse remodelling (=LV response) in patients with heart failure. Intraventricular pressure gradients can be quantified using echocardiography-derived haemodynamic forces (HDF). The aim was to evaluate the association between baseline HDF and LV response and to compare the change of HDF after CRT between LV responders and LV non-responders. Methods and results: The following HDF parameters were assessed: (i) apical-b...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 66, Issue 6, 1 1 2024, Pages ezae440
The effect of virtual reality on postoperative anxiety and pain in patients following cardiac surgery: a randomized controlled trial.
El Mathari S, Shehadeh S, Zwaan WP, Boulidam N, Kuitert L, Twisk JWR, Klautz RJM, de Lind van Wijngaarden R, Veen K, Kluin J
Objectives: The VRECOVERY investigated the impact of virtual reality (VR) distraction therapy on postoperative pain, anxiety and quality of recovery in patients undergoing coronary artery bypass grafting surgery. Methods: A single-centre randomized controlled trial was conducted involving 192 participants, allocated to either the intervention or control group. Participants in the intervention group received VR distraction therapy on postoperative days 1, 2 and 3, while the control group received...
Abstract
