Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6152 results
Cited 28 times since 2008 (1.7 per year) source: EuropePMC
Biochimica et biophysica acta, Volume 1791, Issue 3, 25 4 2008, Pages 191-197 PXR agonism decreases plasma HDL levels in ApoE3-Leiden.CETP mice. de Haan W, de Vries-van der Weij J, Mol IM, Hoekstra M, Romijn JA, Jukema JW, Havekes LM, Princen HM, Rensen PC
Pregnane X receptor (PXR) agonism has been shown to affect multiple steps in both the synthesis and catabolism of HDL, but its integrated effect on HDL metabolism in vivo remains unclear. The aim of this study was to evaluate the net effect of PXR agonism on HDL metabolism in ApoE3-Leiden (E3L) and E3L.CETP mice, well-established models for human-like lipoprotein metabolism. Female mice were fed a diet with increasing amounts of the potent PXR agonist 5-pregnen-3beta-ol-20-one-16alpha-carbonitri... Abstract
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 37, Issue 3, 25 4 2008, Pages 371 Comment on "Clinical endpoints in peripheral endovascular revascularisation trials: a case for standardised definitions Eur J Vasc Endovasc Surg 2008;36:409-9". Breek JC, De Vries J, Hamming JF
Cited 18 times since 2008 (1.1 per year) source: EuropePMC
Patient education and counseling, Volume 76, Issue 1, 20 3 2008, Pages 132-137 Cognitive coping and goal adjustment in people with Peripheral Arterial Disease: relationships with depressive symptoms. Garnefski N, Grol M, Kraaij V, Hamming JF
Objective: The aim was to study relationships between cognitive coping strategies, goal adjustment processes (goal disengagement and re-engagement) and symptoms of depression in people with Peripheral Arterial Disease (PAD). Methods: The sample consisted of 88 patients with PAD. Strategies of cognitive coping, goal disengagement, goal re-engagement, and depression were measured by written questionnaires. The main statistical methods were Pearson correlations and Multiple Regression Analyses. Res... Abstract
Cardiovascular drugs and therapy, Volume 23, Issue 2, 19 3 2008, Pages 103-105 Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: "Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation" by Li et al. Pires NM, Jukema JW
Cited 36 times since 2008 (2.2 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 29, Issue 2, 18 3 2008, Pages 188-194 Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis. de Nooijer R, Bot I, von der Thüsen JH, Leeuwenburgh MA, Overkleeft HS, Kraaijeveld AO, Dorland R, van Santbrink PJ, van Heiningen SH, Westra MM, Kovanen PT, Jukema JW, van der Wall EE, van Berkel TJ, Shi GP, Biessen EA
Objective: A dysbalance of proteases and their inhibitors is instrumental in remodeling of atherosclerotic plaques. One of the proteases implicated in matrix degradation is cathepsin-S (CatS). To address its role in advanced lesion composition, we generated chimeric LDLr(-/-) mice deficient in leukocyte CatS by transplantation with CatS(-/-)xLDLr(-/-) or with LDLr(-/-) bone marrow and administered a high-fat diet. Methods and results: No difference in aortic root lesion size could be detected be... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 20, Issue 5, 17 3 2008, Pages 536-538 Should the left ventricular pacing lead be positioned at the site of latest mechanical activation in cardiac resynchronization therapy? Van Bommel RJ, Schalij MJ, Bax JJ
Cited 36 times since 2008 (2.2 per year) source: EuropePMC
Heart rhythm, Volume 6, Issue 3, 13 2 2008, Pages 305-310 Clinical importance of new-onset atrial fibrillation after cardiac resynchronization therapy. Borleffs CJ, Ypenburg C, van Bommel RJ, Delgado V, van Erven L, Schalij MJ, Bax JJ
Background: Data on the occurrence and implications of new-onset atrial fibrillation (AF) following cardiac resynchronization therapy (CRT) are scarce. We studied the incidence of new onset AF in CRT-defibrillator (CRT-D) recipients. The influence of new-onset AF on echocardiographic response to CRT and the rate of adverse events also were evaluated. Objective: The purpose of this study was to assess the incidence and implications of new-onset AF following CRT. Methods: The study population cons... Abstract
Cited 3 times since 2008 (0.2 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 25, Issue 2, 5 1 2008, Pages 141-144 Atherosclerotic plaque imaging by PET/CT; can inactive, active and mixed plaques be discerned? van der Wall EE, Schuijf JD, Jukema JW, Bax JJ, van der Laarse A
Cited 2 times since 2008 (0.1 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 296, Issue 2, 5 1 2008, Pages H342-9 Cardiac phase-dependent time normalization reduces load dependence of time-varying elastance. Kind T, Westerhof N, Faes TJ, Lankhaar JW, Steendijk P, Vonk-Noordegraaf A
The time-varying elastance concept provides a comprehensive description of the intrinsic mechanical properties of the left ventricle that are assumed to be load independent. Based on pressure-volume measurements obtained with combined pressure conductance catheterization in six open-chest anesthetized sheep, we show that the time to reach end systole (defined as maximal elastance) is progressively prolonged for increasing ventricle pressures, which challenges the original (load-independent) time... Abstract
Cited 21 times since 2008 (1.3 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 36, Issue 4, 3 1 2008, Pages 594-601 Agreement and disagreement between contrast-enhanced magnetic resonance imaging and nuclear imaging for assessment of myocardial viability. Roes SD, Kaandorp TA, Marsan NA, Westenberg JJ, Dibbets-Schneider P, Stokkel MP, Lamb HJ, van der Wall EE, de Roos A, Bax JJ
Purpose: The purpose of this study was to compare contrast-enhanced MRI and nuclear imaging with (99m)Tc-tetrofosmin and (18)F-fluorodeoxyglucose ((18)F-FDG) single photon emission computed tomography (SPECT) for assessment of myocardial viability. Methods: Included in the study were 60 patients with severe ischaemic left ventricular (LV) dysfunction who underwent contrast-enhanced MRI, (99m)Tc-tetrofosmin and (18)F-FDG SPECT. Myocardial segments were assigned a wall motion score from 0 (normoki... Abstract
Cited 24 times since 2008 (1.5 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 31, Issue 12, 1 1 2008, Pages 1628-1639 Noninvasive imaging in cardiac resynchronization therapy--Part 2: Follow-up and optimization of settings. Ypenburg C, Van De Veire N, Westenberg JJ, Bleeker GB, Marsan NA, Henneman MM, Van Der Wall EE, Schalij MJ, Abraham TP, Barold SS, Bax JJ
Cardiac resynchronization therapy (CRT) has become a therapeutic option for drug-refractory heart failure. Several noninvasive imaging techniques play an increasingly important role before and after device implantation. This review highlights the acute and long-term CRT benefits after implantation as assessed with echocardiography and nuclear imaging. Furthermore, optimization of CRT settings, in particular atrioventricular and interventricular delay, will be discussed using echocardiography and... Abstract
Cited 672 times since 2008 (41.1 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 52, Issue 25, 1 1 2008, Pages 2135-2144 Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. Meijboom WB, Meijs MF, Schuijf JD, Cramer MJ, Mollet NR, van Mieghem CA, Nieman K, van Werkhoven JM, Pundziute G, Weustink AC, de Vos AM, Pugliese F, Rensing B, Jukema JW, Bax JJ, Prokop M, Doevendans PA, Hunink MG, Krestin GP, de Feyter PJ
Objectives: This study sought to determine the diagnostic accuracy of 64-slice computed tomographic coronary angiography (CTCA) to detect or rule out significant coronary artery disease (CAD). Background: CTCA is emerging as a noninvasive technique to detect coronary atherosclerosis. Methods: We conducted a prospective, multicenter, multivendor study involving 360 symptomatic patients with acute and stable anginal syndromes who were between 50 and 70 years of age and were referred for diagnostic... Abstract
Cited 4 times since 2008 (0.2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 94, Issue 12, 1 1 2008, Pages 1656-1662 Statins: established indications and controversial subgroups. Jukema JW, Bergheanu SC
Cited 59 times since 2008 (3.6 per year) source: EuropePMC
The Journal of general virology, Volume 89, Issue Pt 12, 1 1 2008, Pages 2933-2942 Evolutionary dynamics of human and avian metapneumoviruses. de Graaf M, Osterhaus ADME, Fouchier RAM, Holmes EC
Human (HMPV) and avian (AMPV) metapneumoviruses are closely related viruses that cause respiratory tract illnesses in humans and birds, respectively. Although HMPV was first discovered in 2001, retrospective studies have shown that HMPV has been circulating in humans for at least 50 years. AMPV was first isolated in the 1970s, and can be classified into four subgroups, A-D. AMPV subgroup C is more closely related to HMPV than to any other AMPV subgroup, suggesting that HMPV has emerged from AMPV... Abstract
Journal of the American College of Cardiology, Volume 52, Issue 24, 1 1 2008, Pages 2032-2042 Highlights of the 2008 Scientific Sessions of the European Society of Cardiology Munich, Germany, August 30 to September 3, 2008. Kristensen SD, Baumgartner H, Casadei B, Drexler H, Eeckhout E, Filippatos G, Fox KA, Perk J, Pierard LA, Poldermans D, Schunkert H, Vardas PE, van der Wall EE, Fox K, Bax JJ
Clinical nuclear medicine, Volume 33, Issue 12, 1 1 2008, Pages 852-855 Comparison of outcome after myocardial infarction in patients with and without abnormalities on previous stress Tc-99m tetrofosmin myocardial perfusion imaging. Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Feringa HH, Noordzij PG, Schouten O, Karagiannis SE, Dunkelgrun M, Poldermans D
Background: Acute myocardial infarction (MI) can occur in patients with previously normal stress myocardial perfusion imaging (MPI). It is not known whether the prognosis of these patients differ from those with MI who had an abnormal MPI on an earlier testing. The aim of this study was to compare the outcome of patients who sustained a MI during follow-up after stress MPI based on the presence or absence of perfusion abnormalities on the earlier test. Methods: We studied 109 patients (age 62 +/... Abstract
Cited 132 times since 2008 (8.1 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 95, Issue 9, 26 4 2008, Pages 715-720 Risk factors and time delay associated with cardiac device infections: Leiden device registry. Lekkerkerker JC, van Nieuwkoop C, Trines SA, van der Bom JG, Bernards A, van de Velde ET, Bootsma M, Zeppenfeld K, Jukema JW, Borleffs JW, Schalij MJ, van Erven L
Aims: A nested case-control study of 75 patients with cardiac device infections (CDI) and 75 matched controls was conducted to evaluate time course, risk factors, culture results and frequency of CDI. Methods and results: CDI occurred in 75/3410 (2.2%) device implantation and revision procedures, performed between 2000 and 2007. The time delay between device procedure and infection ranged from 0 to 64 months (mean 14 (SD 16)), 21 patients (28%) had an early infection (12 months). Of interest, 18... Abstract
Cited 23 times since 2008 (1.4 per year) source: EuropePMC
Journal of vascular surgery, Volume 49, Issue 2, 22 4 2008, Pages 435-41; discussion 441-2 Plasma N-terminal pro-B-type natriuretic peptide as a predictor of perioperative and long-term outcome after vascular surgery. Schouten O, Hoeks SE, Goei D, Bax JJ, Verhagen HJ, Poldermans D
Objective: N-terminal pro-B-type natriuretic peptide (NT-proBNP) is secreted by the heart in response to ventricular wall stress and has prognostic value in patients with heart failure, coronary artery disease, and heart valve abnormalities. Postoperative and long-term outcome is also related to these risk factors. This study assessed the additional prognostic value of NT-proBNP levels as a simple objective risk marker for postoperative cardiac events among vascular surgery patients. Methods: A... Abstract
Cited 8 times since 2008 (0.5 per year) source: EuropePMC
Diabetologia, Volume 52, Issue 2, 22 4 2008, Pages 235-239 Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, de Craen AJ, Ford I, Forouhi NG, Freeman DJ, Jukema JW, Macfarlane PW, Murphy MB, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Prospective Study of Pravastatin in Elderly at Risk Trial Study Group
Aims/hypothesis: The aim of this prospective study was to determine whether circulating intercellular adhesion molecule (ICAM) 1, as a potential surrogate of 'endothelial activation', is more strongly associated with risk of vascular events than with incident diabetes. Methods: We related baseline ICAM-1 levels to vascular events (866 CHD and stroke events in 5,685 participants) and incident diabetes (292 in 4,945 without baseline diabetes) in the elderly over 3.2 years of follow-up. R... Abstract
Cited 55 times since 2008 (3.4 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 1, Issue 6, 18 3 2008, Pages 787-800 Echocardiography in hypertrophic cardiomyopathy: the role of conventional and emerging technologies. Afonso LC, Bernal J, Bax JJ, Abraham TP
Hypertrophic cardiomyopathy is a relatively common inherited cardiomyopathy that is occasionally challenging to differentiate from hypertensive heart disease and athlete hearts on the basis of morphologic or functional abnormalities alone. Echocardiography has traditionally played a preeminent role in the diagnosis, formulation of management strategies, and the prognostication of this complex disease. In this review, we briefly profile the utility and pitfalls of established echocardiographic mo... Abstract