Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7154 results
Cited 1 times since 2021 (0.3 per year) source: EuropePMC
JMIR cardio, Volume 5, Issue 2, 30 5 2021, Pages e27867 Financial Incentives for Healthy Living for Patients With Cardiac Disease From the Perspective of Health Care Professionals: Interview Study. de Buisonjé D, Van der Geer J, Keesman M, Van der Vaart R, Reijnders T, Wentzel J, Kemps H, Kraaijenhagen R, Janssen V, Evers A
Background: A promising new approach to support lifestyle changes in patients with cardiovascular disease (CVD) is the use of financial incentives. Although financial incentives have proven to be effective, their implementation remains controversial, and ethical objections have been raised. It is unknown whether health care professionals (HCPs) involved in CVD care find it acceptable to provide financial incentives to patients with CVD as support for lifestyle change. Objective: This study aims... Abstract
Cited 5 times since 2021 (1.4 per year) source: EuropePMC
Turkish journal of medical sciences, Volume 51, Issue 4, 30 5 2021, Pages 1640-1646 Impact of COVID-19 on serum melatonin levels and sleep parameters in children Yayıcı Köken Ö, Gültutan P, Güngören MS, Bayhan Gİ, Yılmaz D, Gürkaş E, Özyürek H, Çıtak Kurt AN
Background/aim: This study aimed to analyze the serum melatonin levels and changes in sleep patterns in pediatric patients with
coronavirus disease 2019 (COVID-19). Materials and methods: This study was designed as a descriptive, cross-sectional study. Serum melatonin levels and sleep parameters of children with the diagnosis of COVID-19 who had mild and moderate disease (i.e., COVID-19 group) were compared with those of children admitted with non-COVID-19 nonspecific upper respiratory tract inf...
Abstract
Cited 7 times since 2021 (2 per year) source: EuropePMC
Clinical research in cardiology : official journal of the German Cardiac Society, Volume 110, Issue 11, 28 4 2021, Pages 1734-1742 Echocardiography-derived total atrial conduction time (PA-TDI duration): risk stratification and guidance in atrial fibrillation management. Müller P, Weijs B, Bemelmans NMAA, Mügge A, Eckardt L, Crijns HJGM, Bax JJ, Linz D, den Uijl DW
Atrial fibrillation (AF) is a major cause of cardiovascular morbidity and mortality. To early detect and to avoid AF-related complications, several cardiac imaging modalities and approaches aim to quantify the severity of the underlying atrial cardiomyopathy (i.e., the extent of atrial remodeling). However, most established cardiac imaging modalities just incorporate single components of atrial remodeling and do not reflect the complete multifactorial process, which may contribute to their limit... Abstract
Cited 17 times since 2021 (4.8 per year) source: EuropePMC
BMC medicine, Volume 19, Issue 1, 27 4 2021, Pages 211 Interventions to control nosocomial transmission of SARS-CoV-2: a modelling study. Pham TM, Tahir H, van de Wijgert JHHM, Van der Roest BR, Ellerbroek P, Bonten MJM, Bootsma MCJ, Kretzschmar ME
Background: Emergence of more transmissible SARS-CoV-2 variants requires more efficient control measures to limit nosocomial transmission and maintain healthcare capacities during pandemic waves. Yet the relative importance of different strategies is unknown. Methods: We developed an agent-based model and compared the impact of personal protective equipment (PPE), screening of healthcare workers (HCWs), contact tracing of symptomatic HCWs and restricting HCWs from working in multiple units (HCW... Abstract
European heart journal. Case reports, Volume 5, Issue 8, 27 4 2021, Pages ytab288 4D flow MRI of type B dissection with later retrograde progression to type A dissection in Marfan: a case report. van Hout MJP, Juffermans JF, Scholte AJ, Lamb HJ
Background: Due to the malfunction of connective tissue, Marfan patients are at increased risk of aortic dissection. Uncomplicated acute type B dissection is usually managed with medical therapy. Retrograde progression or new type A dissection is a relatively rare but often fatal complication that occur most frequently in the first 6 months after acute type B dissection. Case summary: We present a 31-year-old male with Marfan syndrome and a recent uncomplicated type B dissection from the left su... Abstract
Cited 4 times since 2021 (1.1 per year) source: EuropePMC
Frontiers in veterinary science, Volume 8, 27 4 2021, Pages 686257 Why Test Purchased Cattle in BVDV Control Programs? Van Duijn L, Santman-Berends I, Biesheuvel M, Mars J, Waldeck F, van Schaik G
Bovine viral diarrhea (BVD) is controlled in many countries by detection and culling of persistently infected (PI) animals. The most important risk factor for BVDV introduction is purchase. An introduced cow can be PI and transmit the virus to other cattle in the herd. If she is not PI but is pregnant, there is still a risk because the subsequently born calf may be PI, when she encountered the virus in early pregnancy. To control this risk, all cows > 1 year from non-BVDV-free herds that are... Abstract
Cited 10 times since 2021 (2.8 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 8, Issue 9, 26 4 2021, Pages 102 The Coronary Arteries in Adults after the Arterial Switch Operation: A Systematic Review. Engele LJ, Mulder BJM, Schoones JW, Kiès P, Egorova AD, Vliegen HW, Hazekamp MG, Bouma BJ, Jongbloed MRM
Coronary artery status in adults long after the arterial switch operation (ASO) is unclear. We conducted a systematic review to provide an overview of coronary complications during adulthood and to evaluate the value of routine coronary imaging in adults after ASO, in light of current guidelines. Articles were screened for the inclusion of adult ASO patients and data on coronary complications and findings of coronary imaging were collected. A total of 993 adults were followed with a median avail... Abstract
JTCVS open, Volume 8, 25 4 2021, Pages 249-250 Reply from authors: Prosthesis-patient mismatch is not synonymous with elevated transvalvular pressure gradient. Vriesendorp MD, Klautz RJM
Cited 3 times since 2021 (0.9 per year) source: EuropePMC
BMC medical ethics, Volume 22, Issue 1, 25 4 2021, Pages 114 Practice variation in the informed consent procedure for thrombolysis in acute ischemic stroke: a survey among neurologists and neurology residents. Zonjee VJ, Slenders JPL, de Beer F, Visser MC, Ter Meulen BC, Van den Berg-Vos RM, van Schaik SM
Background: Obtaining informed consent for intravenous thrombolysis in acute ischemic stroke can be challenging, and little is known about if and how the informed consent procedure is performed by neurologists in clinical practice. This study examines the procedure of informed consent for intravenous thrombolysis in acute ischemic stroke in high-volume stroke centers in the Netherlands. Methods: In four high volume stroke centers, neurology residents and attending neurologists received an online... Abstract
Cited 6 times since 2021 (1.7 per year) source: EuropePMC
Patient education and counseling, Volume 105, Issue 5, 25 4 2021, Pages 1123-1129 Experiences with information provision and preferences for decision making of patients with acute stroke. Prick JCM, Zonjee VJ, van Schaik SM, Dahmen R, Garvelink MM, Brouwers PJAM, Saxena R, Keus SHJ, Deijle IA, van Uden-Kraan CF, van der Wees PJ, Van den Berg-Vos RM, Santeon VBHC stroke group
Objective: The aim of this study was to gain insight into experiences of patients with acute stroke regarding information provision and their preferred involvement in decision-making processes during the initial period of hospitalisation. Methods: A sequential explanatory design was used in two independent cohorts of patients with stroke, starting with a survey after discharge from hospital (cohort 1) followed by observations and structured interviews during hospitalisation (cohort 2). Quantitat... Abstract
Cited 7 times since 2021 (2 per year) source: EuropePMC
Oral oncology, Volume 121, 25 4 2021, Pages 105504 An overview of the current clinical status of optical imaging in head and neck cancer with a focus on Narrow Band imaging and fluorescence optical imaging. van Schaik JE, Halmos GB, Witjes MJH, Plaat BEC
Early and accurate identification of head and neck squamous cell carcinoma (HNSCC) is important to improve treatment outcomes and prognosis. New optical imaging techniques may assist in both the diagnostic process as well as in the operative setting by real-time visualization and delineation of tumor. Narrow Band Imaging (NBI) is an endoscopic technique that uses blue and green light to enhance mucosal and submucosal blood vessels, leading to better detection of (pre)malignant lesions showing ab... Abstract
Cited 10 times since 2021 (2.8 per year) source: EuropePMC
Angiogenesis, Volume 25, Issue 1, 25 4 2021, Pages 129-143 PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting. Perrotta P, de Vries MR, Peeters B, Guns PJ, De Meyer GRY, Quax PHA, Martinet W
Vein grafting is a frequently used surgical intervention for cardiac revascularization. However, vein grafts display regions with intraplaque (IP) angiogenesis, which promotes atherogenesis and formation of unstable plaques. Graft neovessels are mainly composed of endothelial cells (ECs) that largely depend on glycolysis for migration and proliferation. In the present study, we aimed to investigate whether loss of the glycolytic flux enzyme phosphofructokinase-2/fructose-2,6-bisphosphatase 3 (PF... Abstract
Cited 11 times since 2021 (3.1 per year) source: EuropePMC
Scientific reports, Volume 11, Issue 1, 24 4 2021, Pages 17121 Differential progression of coronary atherosclerosis according to plaque composition: a cluster analysis of PARADIGM registry data. Yoon YE, Baskaran L, Lee BC, Pandey MK, Goebel B, Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Narula J, Bax JJ, Lin FY, Shaw L, Chang HJ
Patient-specific phenotyping of coronary atherosclerosis would facilitate personalized risk assessment and preventive treatment. We explored whether unsupervised cluster analysis can categorize patients with coronary atherosclerosis according to their plaque composition, and determined how these differing plaque composition profiles impact plaque progression. Patients with coronary atherosclerotic plaque (n = 947; median age, 62 years; 59% male) were enrolled from a prospective multi-national re... Abstract
Cited 3 times since 2021 (0.9 per year) source: EuropePMC
ACS chemical biology, Volume 16, Issue 9, 24 4 2021, Pages 1770-1778 Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function. Schepers AG, Shan J, Cox AG, Huang A, Evans H, Walesky C, Fleming HE, Goessling W, Bhatia SN
The utility of in vitro human disease models is mainly dependent on the availability and functional maturity of tissue-specific cell types. We have previously screened for and identified small molecules that can enhance hepatocyte function in vitro. Here, we characterize the functional effects of one of the hits, FH1, on primary human hepatocytes in vitro, and also in vivo on primary hepatocytes in a zebrafish model. Furthermore, we conducted an analogue screen to establish the structure-activit... Abstract
Cited 10 times since 2021 (2.8 per year) source: EuropePMC
Medical education, Volume 56, Issue 1, 24 4 2021, Pages 82-90 Towards equitable learning environments for medical education: Bias and the intersection of social identities. Bochatay N, Bajwa NM, Ju M, Appelbaum NP, van Schaik SM
Context: Medical educators are increasingly paying attention to how bias creates inequities that affect learners across the medical education continuum. Such bias arises from learners' social identities. However, studies examining bias and social identities in medical education tend to focus on one identity at a time, even though multiple identities often interact to shape individuals' experiences. Methods: This article examines prior studies on bias and social identity in medical educ... Abstract
Cited 72 times since 2021 (20.4 per year) source: EuropePMC
Anaesthesia, Volume 77, Issue 1, 24 4 2021, Pages 28-39 SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. COVIDSurg Collaborative, GlobalSurg Collaborative
SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergo... Abstract
Cited 2 times since 2021 (0.6 per year) source: EuropePMC
Frontiers in physiology, Volume 12, 23 4 2021, Pages 710020 The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes. Ördög B, Teplenin A, De Coster T, Bart CI, Dekker SO, Zhang J, Ypey DL, de Vries AAF, Pijnappels DA
Aim: Channelrhodopsins (ChRs) are a large family of light-gated ion channels with distinct properties, which is of great importance in the selection of a ChR variant for a given application. However, data to guide such selection for cardiac optogenetic applications are lacking. Therefore, we investigated the functioning of different ChR variants in normal and pathological hypertrophic cardiomyocytes subjected to various illumination protocols. Methods and Results: Isolated neonatal rat ventricul... Abstract
Cited 12 times since 2021 (3.4 per year) source: EuropePMC
European journal of heart failure, Volume 23, Issue 10, 22 4 2021, Pages 1597-1609 Guidance on the management of left ventricular assist device (LVAD) supported patients for the non-LVAD specialist healthcare provider: executive summary. Ben Gal T, Ben Avraham B, Milicic D, Crespo-Leiro MG, Coats AJS, Rosano G, Seferovic P, Ruschitzka F, Metra M, Anker S, Filippatos G, Altenberger J, Adamopoulos S, Barac YD, Chioncel O, de Jonge N, Elliston J, Frigerio M, Goncalvesova E, Gotsman I, Grupper A, Hamdan R, Hammer Y, Hasin T, Hill L, Itzhaki Ben Zadok O, Abuhazira M, Lavee J, Mullens W, Nalbantgil S, Piepoli MF, Ponikowski P, Potena L, Ristic A, Ruhparwar A, Shaul A, Tops LF, Tsui S, Winnik S, Jaarsma T, Gustafsson F
The accepted use of left ventricular assist device (LVAD) technology as a good alternative for the treatment of patients with advanced heart failure together with the improved survival of patients on the device and the scarcity of donor hearts has significantly increased the population of LVAD supported patients. Device-related, and patient-device interaction complications impose a significant burden on the medical system exceeding the capacity of LVAD implanting centres. The probability of an L... Abstract
Cited 2 times since 2021 (0.6 per year) source: EuropePMC
JTCVS open, Volume 8, 21 3 2021, Pages 668-676 Incidence and risk factors of unplanned emergency department visits following thoracic surgery. Hazewinkel MHJ, Berendsen RR, van Klink RCJ, Dik H, Wink J, Braun J, de Lind van Wijngaarden RAF
Background: Unplanned visits for care following a surgical procedure can represent a lapse in quality of care. The purpose of this study was to define the proportion of patients undergoing thoracic surgery who return to the emergency department (ED) within 6 months after discharge and the reasons for the returns. In addition, the risk factors for ED visits after thoracic surgery were identified. Methods: All adult patients undergoing thoracic surgery at the Leiden University Medical Center betwe... Abstract
Cited 6 times since 2021 (1.7 per year) source: EuropePMC
International journal of cardiology. Heart & vasculature, Volume 36, 20 3 2021, Pages 100858 Referral and participation in cardiac rehabilitation of patients following acute coronary syndrome; lessons learned. Rodrigo SF, Van Exel HJ, Van Keulen N, Van Winden L, Beeres SLMA, Schalij MJ
Purpose: Cardiac rehabilitation (CR) after hospitalization for acute coronary syndrome (ACS) has shown to reduce mortality, readmissions, and improve quality of life. CR is recommended by international guidelines but previous studies have shown low participation rates. Systematic CR referral might improve CR participation. Methods: The present study evaluates CR referral and CR participation of patients hospitalized for ACS in 2017 and treated according to local protocol, which includes systemat... Abstract