Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6136 results
Cited 10 times since 2016 (1.1 per year) source: EuropePMC
Journal of applied oral science : revista FOB, Volume 24, Issue 1, 1 1 2016, Pages 67-75 Lactobacillus rhamnosus could inhibit Porphyromonas gingivalis derived CXCL8 attenuation. Mendi A, Köse S, Uçkan D, Akca G, Yilmaz D, Aral L, Gültekin SE, Eroğlu T, Kiliç E, Uçkan S
Unlabelled: An increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. P. gingivalis has been noted to have a different way of interacting with the innate immune response of the host compared to other pathogenic bacteria, which is a recognized feature that inhibits CXCL8 expression. Objective: The aim of the study was to determine if P. gingivalis infection modulates the... Abstract
Cited 9 times since 2015 (1 per year) source: EuropePMC
The American journal of cardiology, Volume 117, Issue 6, 30 5 2016, Pages 887-893 Value of Coronary Computed Tomography Angiography in Tailoring Aspirin Therapy for Primary Prevention of Atherosclerotic Events in Patients at High Risk With Diabetes Mellitus. Dimitriu-Leen AC, Scholte AJ, van Rosendael AR, van den Hoogen IJ, Kharagjitsingh AV, Wolterbeek R, Knuuti J, Kroft LJ, Delgado V, Jukema JW, de Graaf MA, Bax JJ
Aspirin use for primary prevention in patients at high risk with diabetes mellitus (DM) is often recommended under the assumption that most patients with DM have coronary artery disease (CAD). However, not all patients may have CAD. The present study evaluated, in 425 patients at high risk with DM (without chest pain syndrome or a history of cardiac disease), the prevalence of CAD on coronary computed tomography angiography (CTA). Moreover, the association between the presence and number of trad... Abstract
Cited 6 times since 2015 (0.7 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 49, Issue 6, 30 5 2016, Pages 1564-1570 Twenty-year experience with the Ross-Konno procedure. Schneider AW, Bökenkamp R, Bruggemans EF, Hazekamp MG
Objectives: The Ross-Konno procedure is a last resort for patients with complex multilevel left ventricular outflow tract obstruction (LVOTO) often having other cardiovascular anomalies. It is typically preceded by multiple surgeries. Literature is scarce on long-term follow-up series. Therefore, we have reviewed our 20-year experience with this procedure in order to provide insights in patients' outcomes and to optimize patient selection. Methods: Between January 1995 and December 2014, 48... Abstract
Cited 56 times since 2015 (6.1 per year) source: EuropePMC
Journal of thrombosis and haemostasis : JTH, Volume 14, Issue 1, 29 5 2016, Pages 121-128 Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. Klok FA, Dzikowska-Diduch O, Kostrubiec M, Vliegen HW, Pruszczyk P, Hasenfuß G, Huisman MV, Konstantinides S, Lankeit M
Unlabelled: Essentials Predicting chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism is hard. We studied 772 patients with pulmonary embolism who were followed for CTEPH (incidence 2.8%). Logistic regression analysis revealed 7 easily collectable clinical variables that combined predict CTEPH. Our score identifies patients at low (0.38%) or higher (10%) risk of CTEPH. Summary: Introduction Validated risk factors for the diagnosis of chronic thromboembolic pulmonary hy... Abstract
Cited 27 times since 2015 (2.9 per year) source: EuropePMC
Frontiers in cellular and infection microbiology, Volume 5, 24 4 2015, Pages 99 Salivary Antimicrobial Peptides in Early Detection of Periodontitis. Güncü GN, Yilmaz D, Könönen E, Gürsoy UK
In the pathogenesis of periodontitis, an infection-induced inflammatory disease of the tooth-supporting tissues, there is a complex interaction between the subgingival microbiota and host tissues. A periodontal diagnostic tool for detecting the initiation and progression of the disease, monitoring the response to therapy, or measuring the degree of susceptibility to future disease progression has been of interest for a long time. The value of various enzymes, proteins, and immunoglobulins, which... Abstract
Cited 3 times since 2015 (0.3 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 17, Issue 3, 20 3 2015, Pages 353 Four-dimensional flow cardiovascular magnetic resonance for the evaluation of the atrial baffle after Mustard repair. van der Palen RL, Westenberg JJ, Hazekamp MG, Kuipers IM, Roest AA
Cited 22 times since 2015 (2.4 per year) source: EuropePMC
European journal of clinical pharmacology, Volume 72, Issue 4, 19 3 2015, Pages 431-437 Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies. Trompet S, Postmus I, Slagboom PE, Heijmans BT, Smit RA, Maier AB, Buckley BM, Sattar N, Stott DJ, Ford I, Westendorp RG, de Craen AJ, Jukema JW
Purpose: In pharmacogenetic research, genetic variation in non-responders and high responders is compared with the aim to identify the genetic loci responsible for this variation in response. However, an important question is whether the non-responders are truly biologically non-responsive or actually non-adherent? Therefore, the aim of this study was to describe, within the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), characteristics of both non-responders and high respond... Abstract
Cited 51 times since 2015 (5.5 per year) source: EuropePMC
European heart journal, Volume 37, Issue 10, 18 3 2015, Pages 811-816 Left ventricular systolic function assessment in secondary mitral regurgitation: left ventricular ejection fraction vs. speckle tracking global longitudinal strain. Kamperidis V, Marsan NA, Delgado V, Bax JJ
Aims: Left ventricular (LV) ejection fraction (LVEF) is currently considered for the decision making of patients with mitral regurgitation (MR). However, LVEF represents change in LV volume between end-diastole and end-systole but does not characterize the intrinsic function of the myocardium. In contrast, speckle-tracking global longitudinal strain (GLS) characterizes myocardial deformation. The present study evaluated whether LV GLS may detect further impairment in LV systolic function in dila... Abstract
Cited 3 times since 2015 (0.3 per year) source: EuropePMC
Heart rhythm, Volume 13, Issue 4, 14 2 2015, Pages 860-869 QRS prolongation after premature stimulation is associated with polymorphic ventricular tachycardia in nonischemic cardiomyopathy: Results from the Leiden Nonischemic Cardiomyopathy Study. Piers SR, Askar SF, Venlet J, Androulakis AF, Kapel GF, de Riva Silva M, Jongbloed JJ, van Tintelen JP, Schalij MJ, Pijnappels DA, Zeppenfeld K
Background: Progressive activation delay after premature stimulation has been associated with ventricular fibrillation in nonischemic cardiomyopathy (NICM). Objectives: The objectives of this study were (1) to investigate prolongation of the paced QRS duration (QRSd) after premature stimulation as a marker of activation delay in NICM, (2) to assess its relation to induced ventricular arrhythmias, and (3) to analyze its underlying substrate by late gadolinium enhancement cardiac magnetic resonanc... Abstract
Cited 12 times since 2015 (1.3 per year) source: EuropePMC
The American journal of cardiology, Volume 117, Issue 5, 14 2 2015, Pages 768-774 Prognostic Value of Coronary Computed Tomography Imaging in Patients at High Risk Without Symptoms of Coronary Artery Disease. Dedic A, Ten Kate GJ, Roos CJ, Neefjes LA, de Graaf MA, Spronk A, Delgado V, van Lennep JE, Moelker A, Ouhlous M, Scholte AJ, Boersma E, Sijbrands EJ, Nieman K, Bax JJ, de Feijter PJ
At present, traditional risk factors are used to guide cardiovascular management of asymptomatic subjects. Intensified surveillance may be warranted in those identified as high risk of developing cardiovascular disease (CVD). This study aims to determine the prognostic value of coronary computed tomography (CT) angiography (CCTA) next to the coronary artery calcium score (CACS) in patients at high CVD risk without symptoms suspect for coronary artery disease (CAD). A total of 665 patients at hig... Abstract
Cited 9 times since 2015 (1 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 32, Issue 4, 14 2 2015, Pages 543-552 Enhanced characterization of calcified areas in intravascular ultrasound virtual histology images by quantification of the acoustic shadow: validation against computed tomography coronary angiography. Broersen A, de Graaf MA, Eggermont J, Wolterbeek R, Kitslaar PH, Dijkstra J, Bax JJ, Reiber JH, Scholte AJ
We enhance intravascular ultrasound virtual histology (VH) tissue characterization by fully automatic quantification of the acoustic shadow behind calcified plaque. VH is unable to characterize atherosclerosis located behind calcifications. In this study, the quantified acoustic shadows are considered calcified to approximate the real dense calcium (DC) plaque volume. In total, 57 patients with 108 coronary lesions were included. A novel post-processing step is applied on the VH images to quanti... Abstract
Cited 1 times since 2015 (0.1 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 23, Issue 5, 11 2 2015, Pages 1176-1179 One-stop-shop cardiac CT: Calcium score, angiography, and myocardial perfusion. van Rosendael AR, Dimitriu-Leen AC, Bax JJ, Kroft LJ, Scholte AJHA
Cited 26 times since 2015 (2.8 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 24, Issue 1, 9 2 2015, Pages 195-206 <sup>18</sup>F-FDG positron emission tomography/computed tomography in infective endocarditis. Salomäki SP, Saraste A, Kemppainen J, Bax JJ, Knuuti J, Nuutila P, Seppänen M, Roivainen A, Airaksinen J, Pirilä L, Oksi J, Hohenthal U
Background: The diagnosis of infective endocarditis (IE), especially the diagnosis of prosthetic valve endocarditis (PVE) is challenging since echocardiographic findings are often scarce in the early phase of the disease. We studied the use of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in IE. Methods: Sixteen patients with suspected PVE and 7 patients with NVE underwent visual evaluation of 18F-FDG-PET/CT. 18F-FDG uptake was measured also... Abstract
Cited 22 times since 2015 (2.4 per year) source: EuropePMC
Heart rhythm, Volume 13, Issue 4, 8 2 2015, Pages 905-912 Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus. Ten Sande JN, Postema PG, Boekholdt SM, Tan HL, van der Heijden JF, de Groot NM, Volders PG, Zeppenfeld K, Boersma LV, Nannenberg EA, Christiaans I, Wilde AA
Background: Familial idiopathic ventricular fibrillation (IVF) is a severe disease entity and is notoriously difficult to manage because there are no clinical risk indicators for premature cardiac arrest. Previously, we identified a link between familial IVF and a risk haplotype on chromosome 7q36 (involving the arrhythmia gene DPP6). Objective: The purpose of this study was to expand our knowledge of familial IVF and to discuss its (extended) clinical characteristics. Methods: We studied 601 fa... Abstract
Cited 20 times since 2015 (2.2 per year) source: EuropePMC
Tuberculosis (Edinburgh, Scotland), Volume 97, 8 2 2015, Pages 163-171 KLRG1 and PD-1 expression are increased on T-cells following tuberculosis-treatment and identify cells with different proliferative capacities in BCG-vaccinated adults. Boer MC, van Meijgaarden KE, Goletti D, Vanini V, Prins C, Ottenhoff TH, Joosten SA
In cancer and chronic infectious diseases, immune checkpoint-blockade of inhibitory receptors can enhance T-cell immunity. In tuberculosis (TB), a chronic infectious disease, prolonged antigen exposure can potentially drive terminal T-cell differentiation towards functional 'exhaustion': in human TB T-cells express PD-1 (programmed cell death protein-1) and CTLA-4 (cytotoxic T-lymphocyte-associated protein-4). However, in murine TB not PD-1 but rather killer cell lectin-like receptor s... Abstract
Cited 6 times since 2015 (0.6 per year) source: EuropePMC
International journal of surgery case reports, Volume 19, 7 1 2015, Pages 8-10 Traumatic rupture of a Meckel's diverticulum due to blunt abdominal trauma in a soccer game: A case report. Tummers WS, van der Vorst JR, Swank DJ
Introduction: a Meckel's diverticulum is one of the most common congenital anomalies of the digestive tract. The reported lifetime complication rate is 4%, mostly due to hemorrhage, obstruction, perforation or inflammation. A symptomatic Meckel's diverticulum due to rupture after blunt abdominal trauma is very rare. We believe this case report is the first reporting a rupture of a Meckel's diverticulum after a low velocity blunt abdominal trauma and outlining the importance of a t... Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 23, Issue 6, 2 1 2015, Pages 1510-1513 One-stop-shop cardiac CT: 3D fusion of CT coronary anatomy and myocardial perfusion for guiding revascularization in complex multivessel disease. van Rosendael AR, Dimitriu-Leen AC, Montero-Cabezas JM, Bax JJ, Kroft LJ, Scholte AJ
Cited 1 times since 2015 (0.1 per year) source: EuropePMC
Circulation, Volume 132, Issue 23, 1 1 2015, Pages e375 Letter Regarding Article, "MicroRNA-155 Exerts Cell-Specific Antiangiogenic but Proarteriogenic Effects During Adaptive Neovascularization". Welten SM, Quax PH, Nossent AY
Cited 16 times since 2015 (1.7 per year) source: Scopus
Behavior research methods, Volume 47, Issue 4, 1 1 2015, Pages 1356-1364 Algorithm-supported visual error correction (AVEC) of heart rate measurements in dogs, Canis lupus familiaris. Schöberl I, Kortekaas K, Schöberl FF, Kotrschal K
Dog heart rate (HR) is characterized by a respiratory sinus arrhythmia, and therefore makes an automatic algorithm for error correction of HR measurements hard to apply. Here, we present a new method of error correction for HR data collected with the Polar system, including (1) visual inspection of the data, (2) a standardized way to decide with the aid of an algorithm whether or not a value is an outlier (i.e., "error"), and (3) the subsequent removal of this error from the data set.... Abstract
Cited 4 times since 2015 (0.4 per year) source: EuropePMC
RMD open, Volume 1, Issue 1, 1 1 2015, Pages e000113 A prediction model for progressive disease in systemic sclerosis. Meijs J, Schouffoer AA, Ajmone Marsan N, Stijnen T, Putter H, Ninaber MK, Huizinga TW, de Vries-Bouwstra JK
Objective: To develop a model that assesses the risk for progressive disease in patients with systemic sclerosis (SSc) over the short term, in order to guide clinical management. Methods: Baseline characteristics and 1 year follow-up results of 163 patients with SSc referred to a multidisciplinary healthcare programme were evaluated. Progressive disease was defined as: death, ≥10% decrease in forced vital capacity, ≥15% decrease in diffusing capacity for carbon monoxide, ≥10% decrease in body we... Abstract