6136 results
Cited 11 times since 2014 (1.1 per year)
source: EuropePMC
European journal of cardiovascular nursing,
Volume 15, Issue 1, 20 3 2014, Pages 72-81
Clinical and psychological characteristics predict future healthcare use in adults with congenital heart disease.
Schoormans D, Sprangers MA, van Melle JP, Pieper PG, van Dijk AP, Sieswerda GT, Hulsbergen-Zwarts MS, Plokker TH, Brunninkhuis LG, Vliegen HW, Mulder BJ
Background: To deliver adequate care to patients with congenital heart disease (CHD), it is important to know which patients use what type of care. This knowledge is valuable, as modification of these factors may be used as means to regulate healthcare use. Our objective was to examine the predictive value of psychological characteristics for future healthcare use, independent of clinical characteristics. Methods: In total 845 adult CHD-patients participated in a longitudinal questionnaire study...
Abstract
Cited 6 times since 2014 (0.6 per year)
source: EuropePMC
Journal of cardiac surgery,
Volume 30, Issue 1, 17 3 2014, Pages 13-19
Aortic valve repair versus replacement for aortic regurgitation: effects on left ventricular remodeling.
Regeer MV, Versteegh MI, Klautz RJ, Stijnen T, Schalij MJ, Bax JJ, Ajmone Marsan N, Delgado V
Background: Left ventricular (LV) reverse remodeling after aortic valve replacement (AVR) for aortic regurgitation (AR) is associated with superior prognosis. The outcomes of valve-sparing aortic root replacement techniques on LV performance have not been compared with LV reverse remodeling in AVR. The present evaluation compared the extent of long-term LV reverse remodeling in patients with aortic root pathology and/or AR who underwent aortic valve repair (AVr) with patients who underwent AVR....
Abstract
Cited 31 times since 2014 (3 per year)
source: EuropePMC
Surgical endoscopy,
Volume 29, Issue 8, 16 3 2014, Pages 2235-2243
Increasing efficiency of surgical training: effects of spacing practice on skill acquisition and retention in laparoscopy training.
Spruit EN, Band GP, Hamming JF
Objectives: The goal of this study was to investigate the effects of spaced versus massed practice on skill acquisition and retention in the context of laparoscopic motor skill training. Background: Reaching proficiency in performing laparoscopic surgery involves extensive training to acquire the required motor skills. Conventionally, training of such skills occurs during a full day training event utilizing surgical simulators that train specific motor skills pertinent to laparoscopic surgery. A...
Abstract
Cited 47 times since 2014 (4.5 per year)
source: EuropePMC
Annals of medicine,
Volume 46, Issue 8, 13 2 2014, Pages 640-652
Morphogenesis and molecular considerations on congenital cardiac septal defects.
Gittenberger-de Groot AC, Calkoen EE, Poelmann RE, Bartelings MM, Jongbloed MR
The primary unseptated heart tube undergoes extensive remodeling including septation at the atrial, atrioventricular, ventricular, and ventriculo-arterial level. Alignment and fusion of the septal components is required to ensure full septation of the heart. Deficiencies lead to septal defects at various levels. Addition of myocardium and mesenchymal tissues from the second heart field (SHF) to the primary heart tube, as well as a population of neural crest cells, provides the necessary cellular...
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
American journal of hypertension,
Volume 28, Issue 4, 8 2 2014, Pages 469-479
Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease.
Poortvliet RK, Lloyd SM, Ford I, Sattar N, de Craen AJ, Wijsman LW, Mooijaart SP, Westendorp RG, Jukema JW, de Ruijter W, Gussekloo J, Stott DJ
Background: Visit-to-visit variability in blood pressure is an independent predictor of cardiovascular disease. This study investigates biological correlates of intra-individual variability in blood pressure in older persons. Methods: Nested observational study within the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) among 3,794 male and female participants (range 70-82 years) with a history of, or risk factors for cardiovascular disease. Individual visit-to-visit variability...
Abstract
International journal of cardiology,
Volume 177, Issue 2, 5 1 2014, Pages e70-1
Computed tomography coronary angiography should be performed in all patients with Marfan Syndrome prior to aortic root replacement.
Winter MM, Koolbergen DR, Groenink M, Franken R, Mulder BJ, Bouma BJ
Abstract
Cited 1069 times since 2014 (102.4 per year)
source: EuropePMC
Nature genetics,
Volume 46, Issue 11, 5 1 2014, Pages 1173-1186
Defining the role of common variation in the genomic and biological architecture of adult human height.
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspers
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated ∼2,000, ∼3,700 and ∼9,500 SNPs explained ∼21%, ∼24% and ∼29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for gen...
Abstract
Cited 7 times since 2014 (0.7 per year)
source: EuropePMC
World journal of surgery,
Volume 38, Issue 10, 1 1 2014, Pages 2551-2557
Impact of explosive devices in modern armed conflicts: in-depth analysis of Dutch battle casualties in southern Afghanistan.
Hoencamp R, Huizinga EP, van Dongen TT, Idenburg FJ, Ramasamy A, Leenen LP, Hamming JF
Background: The patterns and mechanisms of injuries of all Dutch battle casualties (BCs) were analyzed to improve the care for injured service members. We performed an in-depth analysis of all Dutch BCs during the participation of The Netherlands as lead nation in the International Security Assistance Force mission in southern Afghanistan. Methods: Participants were selected from the trauma registry at the Dutch Role 2 Medical Treatment Facility if they met the criteria for Dutch BC between Augu...
Abstract
Cited 15 times since 2014 (1.4 per year)
source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer,
Volume 9, Issue 10, 1 1 2014, Pages 1547-1553
Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases.
den Hengst WA, Hendriks JM, Balduyck B, Rodrigus I, Vermorken JB, Lardon F, Versteegh MI, Braun J, Gelderblom H, Schramel FM, Van Boven WJ, Van Putte BP, Birim Ö, Maat AP, Van Schil PE
Introduction: The 5-year overall survival rate of patients undergoing complete surgical resection of pulmonary metastases (PM) from colorectal cancer (CRC) and sarcoma remains low (20-50%). Local recurrence rate is high (48-66%). Isolated lung perfusion (ILuP) allows the delivery of high-dose locoregional chemotherapy with minimal systemic leakage to improve local control. Methods: From 2006 to 2011, 50 patients, 28 male, median age 57 years (15-76), with PM from CRC (n = 30) or sarcoma (n = 20)...
Abstract
Cited 309 times since 2014 (29.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 64, Issue 16, 1 1 2014, Pages 1641-1654
Prognostic value of fractional flow reserve: linking physiologic severity to clinical outcomes.
Johnson NP, Tóth GG, Lai D, Zhu H, Açar G, Agostoni P, Appelman Y, Arslan F, Barbato E, Chen SL, Di Serafino L, Domínguez-Franco AJ, Dupouy P, Esen AM, Esen OB, Hamilos M, Iwasaki K, Jensen LO, Jiménez-Navarro MF, Katritsis DG, Kocaman SA, Koo BK, López-Palop R, Lorin JD, Miller LH, Muller O, Nam CW, Oud N, Puymirat E, Rieber J, Rioufol G, Rodés-Cabau J, Sedlis SP, Takeishi Y, Tonino PA, Van Belle E, Verna E, Werner GS, Fearon WF, Pijls NH, De Bruyne B, Gould KL
Background: Fractional flow reserve (FFR) has become an established tool for guiding treatment, but its graded relationship to clinical outcomes as modulated by medical therapy versus revascularization remains unclear. Objectives: The study hypothesized that FFR displays a continuous relationship between its numeric value and prognosis, such that lower FFR values confer a higher risk and therefore receive larger absolute benefits from revascularization. Methods: Meta-analysis of study- and patie...
Abstract
Circulation. Arrhythmia and electrophysiology,
Volume 7, Issue 5, 1 1 2014, Pages 992
Response to Letter by Chhabra and Spodick regarding article, "Influence of steroid therapy on the incidence of pericarditis and atrial fibrillation following percutaneous epicardial mapping and ablation for ventricular tachycardia" by Dyrda et al.
Dyrda K, Piers SR, van Huls van Taxis CF, Schalij MJ, Zeppenfeld K
Abstract
Cited 24 times since 2014 (2.3 per year)
source: EuropePMC
Diabetologia,
Volume 57, Issue 12, 30 5 2014, Pages 2513-2520
Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up.
Welsh P, Preiss D, Lloyd SM, de Craen AJ, Jukema JW, Westendorp RG, Buckley BM, Kearney PM, Briggs A, Stott DJ, Ford I, Sattar N
Aims/hypothesis: Insulin resistance is commonly proposed as a precursor to both type 2 diabetes and cardiovascular disease (CVD), yet few studies have directly compared insulin resistance with both outcomes simultaneously and determined whether associations with each outcome differ in strength or are comparable. We assessed the association of fasting insulin and HOMA-IR with incident CVD and diabetes in older people. Methods: In the long-term follow-up of the Prospective Study of Pravastatin in...
Abstract
Cited 18 times since 2014 (1.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 114, Issue 12, 28 4 2014, Pages 1875-1881
Impact of flow and left ventricular strain on outcome of patients with preserved left ventricular ejection fraction and low gradient severe aortic stenosis undergoing aortic valve replacement.
Kamperidis V, van Rosendael PJ, Ng AC, Katsanos S, van der Kley F, Debonnaire P, Joyce E, Sianos G, Marsan NA, Bax JJ, Delgado V
The prognostic implications of flow, assessed by stroke volume index (SVi), and left ventricular (LV) global longitudinal strain on survival of patients with low-gradient severe aortic stenosis (AS) and preserved LV ejection fraction are debated. The aim of this study was to evaluate the impact of flow and LV global longitudinal strain on survival in these patients treated with aortic valve replacement (AVR). Patients with low-gradient severe AS with preserved LV ejection fraction treated with A...
Abstract
Cited 43 times since 2014 (4.1 per year)
source: EuropePMC
Journal of lipid research,
Volume 55, Issue 11, 25 4 2014, Pages 2370-2379
PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE.
Ason B, van der Hoorn JW, Chan J, Lee E, Pieterman EJ, Nguyen KK, Di M, Shetterly S, Tang J, Yeh WC, Schwarz M, Jukema JW, Scott R, Wasserman SM, Princen HM, Jackson S
LDL cholesterol (LDL-C) contributes to coronary heart disease. Proprotein convertase subtilisin/kexin type 9 (PCSK9) increases LDL-C by inhibiting LDL-C clearance. The therapeutic potential for PCSK9 inhibitors is highlighted by the fact that PCSK9 loss-of-function carriers exhibit 15-30% lower circulating LDL-C and a disproportionately lower risk (47-88%) of experiencing a cardiovascular event. Here, we utilized pcsk9(-/-) mice and an anti-PCSK9 antibody to study the role of the LDL receptor (L...
Abstract
Cited 378 times since 2014 (36.1 per year)
source: EuropePMC
Lancet (London, England),
Volume 385, Issue 9965, 24 4 2014, Pages 351-361
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, Chung C, Peasey A, Amuzu A, Li K, Palmen J, Howard P, Cooper JA, Drenos F, Li YR, Lowe G, Gallacher J, Stewart MC, Tzoulaki I, Buxbaum SG, van der A DL, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Stepaniak U, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Veglia F, Ford I, Jukema JW, Westendorp RG, de Borst GJ, de Jong PA, Algra A, Spiering W, Maitland-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Eaton CB, Robinson JG, Duggan D, DIAGRAM Consortium, MAGIC Consortium, InterAct Consortium, Kjekshus J, Downs JR, Gotto AM, Keech AC, Marchioli R, Tognoni G, Sever PS, Poulter NR, Waters DD, Pedersen TR, Amarenco P, Nakamura H, McMurray JJ, Lewsey JD, Chasman DI, Ridker PM, Maggioni AP, Tavazzi L, Ray KK, Seshasai SR, Manson JE, Pr
Background: Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the intended drug target. Methods: We used single nucleotide polymorphisms in the HMGCR gene, rs17238484 (for the main analysis) and rs12916 (for a subsidiary analysis) as proxies for HMGCR inhibition by statins. We examined associations of these variants with plasma lipid, glucose, and in...
Abstract
Cited 9 times since 2014 (0.9 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 42, Issue 1, 19 3 2014, Pages 160-167
Super-resolution reconstruction of late gadolinium-enhanced MRI for improved myocardial scar assessment.
Dzyubachyk O, Tao Q, Poot DH, Lamb HJ, Zeppenfeld K, Lelieveldt BP, van der Geest RJ
Purpose: To develop and validate a method for improving image resolution of late gadolinium-enhanced (LGE) magnetic resonance imaging (MRI) for accurate assessment of myocardial scar. Materials and methods: In a cohort of 37 postinfarction patients, LGE was performed prior to ventricular tachycardia catheter ablation therapy at 1.5T. A super-resolution reconstruction (SRR) technique was applied to the three anisotropic views: short-axis (SA), two-chamber, and four-chamber, to reconstruct a singl...
Abstract
Cited 7 times since 2014 (0.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 114, Issue 11, 16 3 2014, Pages 1646-1650
Relation between coronary arterial dominance and left ventricular ejection fraction after ST-segment elevation acute myocardial infarction in patients having percutaneous coronary intervention.
Veltman CE, Hoogslag GE, Kharbanda RK, de Graaf MA, van Zwet EW, van der Hoeven BL, Delgado V, Bax JJ, Scholte AJ
The presence of a left dominant coronary artery system is associated with worse outcome after ST-segment elevation myocardial infarction (STEMI) compared with right dominance or a balanced coronary artery system. However, the association between coronary arterial dominance and left ventricular (LV) function at follow-up after STEMI is unclear. The present study aimed at evaluating the relation between coronary arterial dominance and LV ejection fraction (LVEF) shortly after STEMI and at 12-month...
Abstract
Cited 12 times since 2014 (1.1 per year)
source: EuropePMC
European journal of epidemiology,
Volume 29, Issue 11, 12 2 2014, Pages 841-850
Comparing a marginal structural model with a Cox proportional hazard model to estimate the effect of time-dependent drug use in observational studies: statin use for primary prevention of cardiovascular disease as an example from the Rotterdam Study.
de Keyser CE, Leening MJ, Romio SA, Jukema JW, Hofman A, Ikram MA, Franco OH, Stijnen T, Stricker BH
When studying the causal effect of drug use in observational data, marginal structural modeling (MSM) can be used to adjust for time-dependent confounders that are affected by previous treatment. The objective of this study was to compare traditional Cox proportional hazard models (with and without time-dependent covariates) with MSM to study causal effects of time-dependent drug use. The example of primary prevention of cardiovascular disease (CVD) with statins was examined using up to 17.7 yea...
Abstract
Cited 9 times since 2014 (0.9 per year)
source: EuropePMC
European heart journal. Acute cardiovascular care,
Volume 4, Issue 3, 10 2 2014, Pages 254-262
Contemporary inter-hospital transfer patterns for the management of acute coronary syndrome patients: findings from the EPICOR study.
Sinnaeve PR, Zeymer U, Bueno H, Danchin N, Medina J, Sánchez-Covisa J, Licour M, Annemans L, Jukema JW, Pocock S, Storey RF, Van de Werf F
Aim: The EPICOR observational study was designed to describe antithrombotic strategies in a broad acute coronary syndrome (ACS) population; it also included information on inter-hospital transfers and institutional resources. Methods and results: EPICOR enrolled 10,568 consecutively discharged patients with ST-elevation (STE) or non-STE (NSTE) ACS in 555 centres in 20 countries across Europe and Latin America. Patients were categorized as non-transferred, transferred in from another hospital and...
Abstract
Cited 20 times since 2014 (1.9 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 9, 1 1 2014, Pages 363-369
Normal and abnormal development of the aortic wall and valve: correlation with clinical entities.
Grewal N, DeRuiter MC, Jongbloed MR, Goumans MJ, Klautz RJ, Poelmann RE, Gittenberger-de Groot AC
Dilation of the wall of the thoracic aorta can be found in patients with a tricuspid (TAV) as well as a bicuspid aortic valve (BAV) with and without a syndromic component. BAV is the most common congenital cardiovascular malformation, with a population prevalence of 0.5-2 %. The clinical course is often characterised by aneurysm formation and in some cases dissection. The non-dilated aortic wall is less well differentiated in all BAV as compared with TAV, thereby conferring inherent developmenta...
Abstract
