6205 results
Cited 9 times since 2014 (0.9 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 10, Issue 7, 1 1 2014, Pages 884-886
Tools & Techniques - Clinical: 3D transoesophageal echocardiography for selecting and guiding in percutaneous mitral valve repair using MitraClip.
Debonnaire P, Delgado V, Bax JJ, Marsan NA
Abstract
Cited 13 times since 2014 (1.2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 11, 1 1 2014, Pages 484-490
Role of the ECG in initial acute coronary syndrome triage: primary PCI regardless presence of ST elevation or of non-ST elevation.
IJkema BB, Bonnier JJ, Schoors D, Schalij MJ, Swenne CA
The major initial triaging decision in acute coronary syndrome (ACS) is whether or not percutaneous coronary intervention (PCI) is the primary treatment. Current guidelines recommend primary PCI in ST-elevation ACS (STEACS) and initial antithrombotic therapy in non-ST-elevation ACS (NSTEACS). This review probes the question whether this decision can indeed be based on the ECG. Genesis of STE/NSTE ECGs depends on the coronary anatomy, collateral circulation and site of the culprit lesion. Other c...
Abstract
Cited 17 times since 2014 (1.6 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 78, Issue 5, 1 1 2014, Pages 950-960
Evaluation of lecithinized human recombinant super oxide dismutase as cardioprotectant in anthracycline-treated breast cancer patients.
Broeyer FJ, Osanto S, Suzuki J, de Jongh F, van Slooten H, Tanis BC, Bruning T, Bax JJ, Ritsema van Eck HJ, de Kam ML, Cohen AF, Mituzhima Y, Burggraaf J
Aim: Anthracycline-induced cardiotoxicity is (partly) mediated by free radical overload. A randomized study was performed in breast cancer patients to investigate whether free radical scavenger super oxide dismutase (SOD) protects against anthracycline-induced cardiotoxicity as measured by changes in echo, electrocardiography and an array of biomarkers. Method and results: Eighty female, chemotherapy-naïve breast cancer patients (median age 49, range 24-67 years) scheduled for four or five cours...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 22, Issue 11, 1 1 2014, Pages 491-492
Image-guided intramyocardial cell injection: putting a puzzle piece in the right place.
Ramkisoensing AA, Atsma DE
Abstract
Cited 141 times since 2014 (13.3 per year)
source: EuropePMC
Vaccine,
Volume 32, Issue 52, 30 5 2014, Pages 7098-7107
A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human.
van Dissel JT, Joosten SA, Hoff ST, Soonawala D, Prins C, Hokey DA, O'Dee DM, Graves A, Thierry-Carstensen B, Andreasen LV, Ruhwald M, de Visser AW, Agger EM, Ottenhoff TH, Kromann I, Andersen P
Here, we report on a first-in-man trial where the tuberculosis (TB) vaccine Ag85B-ESAT-6 (H1) was adjuvanted with escalating doses of a novel liposome adjuvant CAF01. On their own, protein antigens cannot sufficiently induce immune responses in humans, and require the addition of an adjuvant system to ensure appropriate delivery and concomitant immune activation. To date no approved adjuvants are available for induction of cellular immunity, which seems essential for a number of vaccines, includ...
Abstract
Cited 57 times since 2014 (5.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 115, Issue 2, 29 5 2014, Pages 234-242
Value of the "TAVI2-SCORe" versus surgical risk scores for prediction of one year mortality in 511 patients who underwent transcatheter aortic valve implantation.
Debonnaire P, Fusini L, Wolterbeek R, Kamperidis V, van Rosendael P, van der Kley F, Katsanos S, Joyce E, Tamborini G, Muratori M, Gripari P, Bax JJ, Marsan NA, Pepi M, Delgado V
A bedside-available transcatheter aortic valve implantation (TAVI)-dedicated prognostic risk score is an unmet clinical need. We aimed to develop such a risk score predicting 1-year mortality post-TAVI and to compare it with the performance of the logistic EuroSCORE (LES) I and LES-II and the Society of Thoracic Surgeons' (STS) score. Baseline variables of 511 consecutive patients who underwent TAVI that were independently associated with 1-year mortality post-TAVI were included in the &quo...
Abstract
Cited 14 times since 2014 (1.3 per year)
source: EuropePMC
Stroke,
Volume 45, Issue 12, 28 4 2014, Pages 3508-3513
Polygenic overlap between kidney function and large artery atherosclerotic stroke.
Holliday EG, Traylor M, Malik R, Bevan S, Maguire J, Koblar SA, Sturm J, Hankey GJ, Oldmeadow C, McEvoy M, Sudlow C, Rothwell PM, Coresh J, Hamet P, Tremblay J, Turner ST, de Andrade M, Rao M, Schmidt R, Crick PA, Robino A, Peralta CA, Jukema JW, Mitchell P, Rosas SE, Wang JJ, Scott RJ, Dichgans M, Mitchell BD, Kao WH, Fox CS, Levi C, Attia J, Markus HS, CKDGen Consortium and the International Stroke Genetics Consortium
Background and purpose: Epidemiological studies show strong associations between kidney dysfunction and risk of ischemic stroke (IS), the mechanisms of which are incompletely understood. We investigated whether these associations may reflect shared heritability because of a common polygenic basis and whether this differed for IS subtypes. Methods: Polygenic models were derived using genome-wide association studies meta-analysis results for 3 kidney traits: estimated glomerular filtration rate us...
Abstract
Cited 16 times since 2014 (1.5 per year)
source: EuropePMC
The Journal of biological chemistry,
Volume 289, Issue 51, 27 4 2014, Pages 35421-35430
Differential complement activation pathways promote C3b deposition on native and acetylated LDL thereby inducing lipoprotein binding to the complement receptor 1.
Klop B, van der Pol P, van Bruggen R, Wang Y, de Vries MA, van Santen S, O'Flynn J, van de Geijn GJ, Njo TL, Janssen HW, de Man P, Jukema JW, Rabelink TJ, Rensen PC, van Kooten C, Cabezas MC
Lipoproteins can induce complement activation resulting in opsonization and binding of these complexes to complement receptors. We investigated the binding of opsonized native LDL and acetylated LDL (acLDL) to the complement receptor 1 (CR1). Binding of complement factors C3b, IgM, C1q, mannose-binding lectin (MBL), and properdin to LDL and acLDL were investigated by ELISA. Subsequent binding of opsonized LDL and acLDL to CR1 on CR1-transfected Chinese Hamster Ovarian cells (CHO-CR1) was tested...
Abstract
Cited 10 times since 2014 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 31, Issue 2, 24 4 2014, Pages 369-377
Preprocedural magnetic resonance imaging for image-guided catheter ablation of scar-related ventricular tachycardia.
Tao Q, Piers SR, Lamb HJ, Zeppenfeld K, van der Geest RJ
To present and validate a highly automated MRI analysis workflow for image-guided catheter ablation of scar-related ventricular tachycardia (VT) ablation procedures. A cohort of 15 post-infarction patients underwent MRI prior to VT ablation. The MRI study included a black-blood turbo spin echo sequence for visualizing the aortic root and ostium of the left main (LM) coronary artery, and a 3D late gadolinium enhanced sequence for visualizing the LV anatomy and myocardial scar substrate. Semi-auto...
Abstract
Cited 15 times since 2014 (1.4 per year)
source: EuropePMC
European journal of cardiovascular nursing,
Volume 15, Issue 1, 20 3 2014, Pages 72-81
Clinical and psychological characteristics predict future healthcare use in adults with congenital heart disease.
Schoormans D, Sprangers MA, van Melle JP, Pieper PG, van Dijk AP, Sieswerda GT, Hulsbergen-Zwarts MS, Plokker TH, Brunninkhuis LG, Vliegen HW, Mulder BJ
Background: To deliver adequate care to patients with congenital heart disease (CHD), it is important to know which patients use what type of care. This knowledge is valuable, as modification of these factors may be used as means to regulate healthcare use. Our objective was to examine the predictive value of psychological characteristics for future healthcare use, independent of clinical characteristics. Methods: In total 845 adult CHD-patients participated in a longitudinal questionnaire study...
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
Journal of cardiac surgery,
Volume 30, Issue 1, 17 3 2014, Pages 13-19
Aortic valve repair versus replacement for aortic regurgitation: effects on left ventricular remodeling.
Regeer MV, Versteegh MI, Klautz RJ, Stijnen T, Schalij MJ, Bax JJ, Ajmone Marsan N, Delgado V
Background: Left ventricular (LV) reverse remodeling after aortic valve replacement (AVR) for aortic regurgitation (AR) is associated with superior prognosis. The outcomes of valve-sparing aortic root replacement techniques on LV performance have not been compared with LV reverse remodeling in AVR. The present evaluation compared the extent of long-term LV reverse remodeling in patients with aortic root pathology and/or AR who underwent aortic valve repair (AVr) with patients who underwent AVR....
Abstract
Cited 39 times since 2014 (3.7 per year)
source: EuropePMC
Surgical endoscopy,
Volume 29, Issue 8, 16 3 2014, Pages 2235-2243
Increasing efficiency of surgical training: effects of spacing practice on skill acquisition and retention in laparoscopy training.
Spruit EN, Band GP, Hamming JF
Objectives: The goal of this study was to investigate the effects of spaced versus massed practice on skill acquisition and retention in the context of laparoscopic motor skill training. Background: Reaching proficiency in performing laparoscopic surgery involves extensive training to acquire the required motor skills. Conventionally, training of such skills occurs during a full day training event utilizing surgical simulators that train specific motor skills pertinent to laparoscopic surgery. A...
Abstract
Cited 49 times since 2014 (4.6 per year)
source: EuropePMC
Annals of medicine,
Volume 46, Issue 8, 13 2 2014, Pages 640-652
Morphogenesis and molecular considerations on congenital cardiac septal defects.
Gittenberger-de Groot AC, Calkoen EE, Poelmann RE, Bartelings MM, Jongbloed MR
The primary unseptated heart tube undergoes extensive remodeling including septation at the atrial, atrioventricular, ventricular, and ventriculo-arterial level. Alignment and fusion of the septal components is required to ensure full septation of the heart. Deficiencies lead to septal defects at various levels. Addition of myocardium and mesenchymal tissues from the second heart field (SHF) to the primary heart tube, as well as a population of neural crest cells, provides the necessary cellular...
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
American journal of hypertension,
Volume 28, Issue 4, 8 2 2014, Pages 469-479
Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease.
Poortvliet RK, Lloyd SM, Ford I, Sattar N, de Craen AJ, Wijsman LW, Mooijaart SP, Westendorp RG, Jukema JW, de Ruijter W, Gussekloo J, Stott DJ
Background: Visit-to-visit variability in blood pressure is an independent predictor of cardiovascular disease. This study investigates biological correlates of intra-individual variability in blood pressure in older persons. Methods: Nested observational study within the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) among 3,794 male and female participants (range 70-82 years) with a history of, or risk factors for cardiovascular disease. Individual visit-to-visit variability...
Abstract
International journal of cardiology,
Volume 177, Issue 2, 5 1 2014, Pages e70-1
Computed tomography coronary angiography should be performed in all patients with Marfan Syndrome prior to aortic root replacement.
Winter MM, Koolbergen DR, Groenink M, Franken R, Mulder BJ, Bouma BJ
Abstract
Cited 1251 times since 2014 (117.6 per year)
source: EuropePMC
Nature genetics,
Volume 46, Issue 11, 5 1 2014, Pages 1173-1186
Defining the role of common variation in the genomic and biological architecture of adult human height.
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspers
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated ∼2,000, ∼3,700 and ∼9,500 SNPs explained ∼21%, ∼24% and ∼29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for gen...
Abstract
Cited 8 times since 2014 (0.8 per year)
source: EuropePMC
World journal of surgery,
Volume 38, Issue 10, 1 1 2014, Pages 2551-2557
Impact of explosive devices in modern armed conflicts: in-depth analysis of Dutch battle casualties in southern Afghanistan.
Hoencamp R, Huizinga EP, van Dongen TT, Idenburg FJ, Ramasamy A, Leenen LP, Hamming JF
Background: The patterns and mechanisms of injuries of all Dutch battle casualties (BCs) were analyzed to improve the care for injured service members. We performed an in-depth analysis of all Dutch BCs during the participation of The Netherlands as lead nation in the International Security Assistance Force mission in southern Afghanistan. Methods: Participants were selected from the trauma registry at the Dutch Role 2 Medical Treatment Facility if they met the criteria for Dutch BC between Augu...
Abstract
Cited 17 times since 2014 (1.6 per year)
source: EuropePMC
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer,
Volume 9, Issue 10, 1 1 2014, Pages 1547-1553
Phase II multicenter clinical trial of pulmonary metastasectomy and isolated lung perfusion with melphalan in patients with resectable lung metastases.
den Hengst WA, Hendriks JM, Balduyck B, Rodrigus I, Vermorken JB, Lardon F, Versteegh MI, Braun J, Gelderblom H, Schramel FM, Van Boven WJ, Van Putte BP, Birim Ö, Maat AP, Van Schil PE
Introduction: The 5-year overall survival rate of patients undergoing complete surgical resection of pulmonary metastases (PM) from colorectal cancer (CRC) and sarcoma remains low (20-50%). Local recurrence rate is high (48-66%). Isolated lung perfusion (ILuP) allows the delivery of high-dose locoregional chemotherapy with minimal systemic leakage to improve local control. Methods: From 2006 to 2011, 50 patients, 28 male, median age 57 years (15-76), with PM from CRC (n = 30) or sarcoma (n = 20)...
Abstract
Cited 377 times since 2014 (35.4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 64, Issue 16, 1 1 2014, Pages 1641-1654
Prognostic value of fractional flow reserve: linking physiologic severity to clinical outcomes.
Johnson NP, Tóth GG, Lai D, Zhu H, Açar G, Agostoni P, Appelman Y, Arslan F, Barbato E, Chen SL, Di Serafino L, Domínguez-Franco AJ, Dupouy P, Esen AM, Esen OB, Hamilos M, Iwasaki K, Jensen LO, Jiménez-Navarro MF, Katritsis DG, Kocaman SA, Koo BK, López-Palop R, Lorin JD, Miller LH, Muller O, Nam CW, Oud N, Puymirat E, Rieber J, Rioufol G, Rodés-Cabau J, Sedlis SP, Takeishi Y, Tonino PA, Van Belle E, Verna E, Werner GS, Fearon WF, Pijls NH, De Bruyne B, Gould KL
Background: Fractional flow reserve (FFR) has become an established tool for guiding treatment, but its graded relationship to clinical outcomes as modulated by medical therapy versus revascularization remains unclear. Objectives: The study hypothesized that FFR displays a continuous relationship between its numeric value and prognosis, such that lower FFR values confer a higher risk and therefore receive larger absolute benefits from revascularization. Methods: Meta-analysis of study- and patie...
Abstract
Circulation. Arrhythmia and electrophysiology,
Volume 7, Issue 5, 1 1 2014, Pages 992
Response to Letter by Chhabra and Spodick regarding article, "Influence of steroid therapy on the incidence of pericarditis and atrial fibrillation following percutaneous epicardial mapping and ablation for ventricular tachycardia" by Dyrda et al.
Dyrda K, Piers SR, van Huls van Taxis CF, Schalij MJ, Zeppenfeld K
Abstract
