Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6125 results
Cited 16 times since 2003 (0.7 per year) source: EuropePMC
Journal of hypertension, Volume 21, Issue 10, 1 1 2003, Pages 1945-1951 Prediction of cardiac death in hypertensive patients with suspected or known coronary artery disease by stress technetium-99m tetrofosmin myocardial perfusion imaging. Elhendy A, Schinkel AF, Van Domburg RT, Bax JJ, Poldermans D
Background: There are currently insufficient data to indicate a role for stress myocardial perfusion imaging as a prognostic tool in hypertensive patients. Objectives: To assess the incremental value of stress myocardial perfusion imaging for the prediction of cardiac death in hypertensive patients relative to clinical data. Patients: We studied 601 hypertensive patients (aged 59 +/- 10 years, 387 men) who underwent exercise bicycle or dobutamine (up to 40 microg/kg per min) stress technetium-99... Abstract
Cited 19 times since 2003 (0.9 per year) source: EuropePMC
Anesthesia and analgesia, Volume 97, Issue 4, 1 1 2003, Pages 950-957 Perioperative assessment of left ventricular function by pressure-volume loops using the conductance catheter method. Tulner SAF, Klautz RJM, van Rijk-Zwikker GL, Engbers FHM, Bax JJ, Baan J, van der Wall EE, Dion RA, Steendijk P
Unlabelled: Interpretation of perioperative measurements of cardiac function during cardiac surgery is complicated by changes in loading conditions induced by anesthesia, cardiopulmonary bypass (CPB), and the surgical procedure itself. Quantification of left ventricular (LV) function by pressure-volume relations as obtained by the conductance catheter would be advantageous because load-independent indices can be determined. Accordingly, we evaluated methodological aspects of the conductance-cath... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 11, Issue 10, 1 1 2003, Pages 416-417 Noncompaction cardiomyopathy. Jongbloed MR, Bax JJ, Schalij MJ, van der Wall EE
Cited 61 times since 2003 (2.8 per year) source: Scopus
Reproduction (Cambridge, England), Volume 126, Issue 4, 1 1 2003, Pages 469-480 Proliferation and apoptosis in bovine placentomes during pregnancy and around induced and spontaneous parturition as well as in cows retaining the fetal membranes. Boos A, Janssen V, Mülling C
Placental growth can be achieved by either cellular proliferation or hypertrophy. Tissue regeneration and the nutrition of the fetus via embryotrophe require high rates of cellular turnover and the so-called pre-term 'maturation' of the placenta is correlated with a reduction of maternal crypt epithelial cells. Placentomes of 45 pregnant cows were collected from an abattoir to assess the role of proliferation and apoptosis in placental physiology and pathology. Placentomes were also ta... Abstract
Cited 1 times since 2003 (0 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 19, Issue 5, 1 1 2003, Pages 367-369 Congenital coronary artery anomalies angiographic classification revisited. Vliegen HW, Bruschke AV
Cited 80 times since 2003 (3.7 per year) source: EuropePMC
Journal of cell science, Volume 116, Issue Pt 19, 1 1 2003, Pages 3971-3984 Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus. Ritzi M, Tillack K, Gerhardt J, Ott E, Humme S, Kremmer E, Hammerschmidt W, Schepers A
The sequential binding of the origin recognition complex (ORC), Cdc6p and the minichromosome maintenance proteins (MCM2-7) mediates replication competence at eukaryotic origins of DNA replication. The latent origin of Epstein-Barr virus, oriP, is a viral origin known to recruit ORC. OriP also binds EBNA1, a virally encoded protein that lacks any activity predicted to be required for replication initiation. Here, we used chromatin immunoprecipitation and chromatin binding to compare the cell-cycl... Abstract
Cited 20 times since 2003 (0.9 per year) source: EuropePMC
Pacing and clinical electrophysiology : PACE, Volume 26, Issue 10, 1 1 2003, Pages 2042-2044 Resynchronization therapy after congenital heart surgery to improve left ventricular function. Roofthooft MT, Blom NA, Rijlaarsdam ME, Bökenkamp R, Ottenkamp J, Schalij MJ, Bax JJ, Hazekamp MG
This report describes the mid-term beneficial hemodynamic effect of biventricular pacing in an infant with congestive heart failure after congenital heart surgery, due to resynchronization of the left and right ventricle, optimization of the AV delay, and (partial) correction of the LV dyssynchrony. Abstract
Cited 18 times since 2003 (0.8 per year) source: EuropePMC
Journal of cardiovascular electrophysiology, Volume 14, Issue 10, 1 1 2003, Pages 1110-1112 Transvenous biventricular pacing in a child after congenital heart surgery as an alternative therapy for congestive heart failure. Blom NA, Bax JJ, Ottenkamp J, Schalij MJ
Transvenous Biventricular Pacing in Children. Cardiac resynchronization therapy improves short-term and long-term hemodynamics in adult patients with congestive heart failure and left bundle branch block. We describe the feasibility of transvenous biventricular pacemaker implantation in a 6-year-old child with heart failure and wide QRS complex after congenital heart surgery. Myocardial tissue Doppler imaging was used to demonstrate intraventricular dyssynchrony and resynchronization after cardi... Abstract
Cited 30 times since 2003 (1.4 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 126, Issue 4, 1 1 2003, Pages 1053-1060 Pulmonary artery remodeling in transposition of the great arteries: relevance for neoaortic root dilatation. Lalezari S, Hazekamp MG, Bartelings MM, Schoof PH, Gittenberger-De Groot AC
Objective: Transposition of the great arteries is currently treated by performing the arterial switch operation. Dilatation of the neoaortic root is a late complication with unknown cause. Samples of patients with untreated transposition of the great arteries and patients with normally related great arteries were compared to investigate a possible role for vascular remodeling in the dilatation process. Methods: Aortic and pulmonary artery vessel wall and sinus samples were taken from 20 untreate... Abstract
Cited 60 times since 2003 (2.8 per year) source: EuropePMC
Circulation, Volume 108, Issue 17, 29 5 2003, Pages 2099-2106 Voltage and activation mapping: how the recording technique affects the outcome of catheter ablation procedures in patients with congenital heart disease. de Groot NM, Schalij MJ, Zeppenfeld K, Blom NA, Van der Velde ET, Van der Wall EE
Background: Endocardial mapping is mandatory before radiofrequency catheter ablation (RFCA). Mapping can be performed with either unipolar or bipolar recordings. Impact of the recording technique used was studied in patients with and without structural heart disease using the 3D electroanatomic CARTO mapping system. Methods and results: Patients (n=44; 16 males; age 43+/-16 years) referred for RFCA of atrial flutter (AFL, n=18), focal atrial tachycardia (FAT, n=4), AV nodal reentrant tachycardia... Abstract
Cited 4 times since 2003 (0.2 per year) source: EuropePMC
Radiology, Volume 228, Issue 3, 1 1 2003, Pages 834-841 Vein graft function improvement after percutaneous intervention: evaluation with MR flow mapping. Langerak SE, Vliegen HW, Jukema JW, Zwinderman AH, Lamb HJ, de Roos A, van der Wall EE
Purpose: To provide functional reference values in single and sequential vein grafts by using magnetic resonance (MR) flow mapping and to examine the effect of percutaneous intervention (PCI) on coronary artery bypass graft function. Materials and methods: Fast MR flow mapping at baseline and during adenosine-induced stress was performed in 39 nonstenotic single vein grafts and 20 nonstenotic sequential vein grafts, as well as in 15 stenotic vein grafts before and 7.3 weeks +/- 1.5 after success... Abstract
Cited 37 times since 2003 (1.7 per year) source: EuropePMC
Circulation, Volume 108 Suppl 1, 1 1 2003, Pages II39-42 Early versus delayed revascularization in patients with ischemic cardiomyopathy and substantial viability: impact on outcome. Bax JJ, Schinkel AF, Boersma E, Rizzello V, Elhendy A, Maat A, Roelandt JR, van der Wall EE, Poldermans D
Background: Patients with ischemic cardiomyopathy and viable myocardium may improve in function and prognosis following revascularization. Delayed revascularization may result in less favorable outcome, and therefore the impact of timing of revascularization on long-term outcome was evaluated. Methods and results: Patients (n=85) with ischemic cardiomyopathy and substantial viability (>or=25% of the left ventricle) on dobutamine stress echocardiography underwent surgical revascularization. Ba... Abstract
Cited 11 times since 2003 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 92, Issue 5, 1 1 2003, Pages 613-616 Effect of atorvastatin on myocardial contractile reserve assessed by tissue Doppler imaging in moderately hypercholesterolemic patients without heart disease. Bountioukos M, Rizzello V, Krenning BJ, Bax JJ, Kertai MD, Vourvouri EC, Schinkel AF, Biagini E, Boersma E, Roelandt JR, Poldermans D
An improvement in myocardial longitudinal systolic velocities, assessed by pulsed-wave tissue Doppler imaging during low-dose dobutamine infusion, was observed at 6-month follow-up after 6 months of treatment with atorvastatin. Our findings indicate a favorable effect of atorvastatin on contractile reserve, possibly through an enhancement of flow-dependent coronary dilatation during stress. Abstract
Cited 4 times since 2003 (0.2 per year) source: EuropePMC
European heart journal, Volume 24, Issue 17, 1 1 2003, Pages 1541-1542 Dobutamine echocardiography: a diagnostic tool comes of age. Poldermans D, Bax JJ
Cited 8 times since 2003 (0.4 per year) source: EuropePMC
The American journal of cardiology, Volume 92, Issue 6, 1 1 2003, Pages 712-715 Relation between QT dispersion and myocardial viability in ischemic cardiomyopathy. Schinkel AF, Bountioukos M, Poldermans D, Elhendy A, Valkema R, Vourvouri EC, Biagini E, Rizzello V, Kertai MD, Krenning B, Krenning EP, Roelandt JR, Bax JJ
The aim of this study was to evaluate the relation between QT dispersion and myocardial viability as assessed by single-photon emission computed tomography. The study population included 97 consecutive patients with severely impaired left ventricular function secondary to chronic coronary artery disease. Patients with a low QT dispersion had a substantial amount of viable myocardium, whereas patients with a high QT dispersion had predominantly nonviable scar tissue. Abstract
Cited 45 times since 2003 (2.1 per year) source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 10, Issue 5, 1 1 2003, Pages 543-556 PET myocardial glucose metabolism and perfusion imaging: Part 1-Guidelines for data acquisition and patient preparation. Bacharach SL, Bax JJ, Case J, Delbeke D, Kurdziel KA, Martin WH, Patterson RE
Cited 162 times since 2003 (7.5 per year) source: EuropePMC
Arthritis and rheumatism, Volume 48, Issue 9, 1 1 2003, Pages 2489-2500 Citrullination of synovial proteins in murine models of rheumatoid arthritis. Vossenaar ER, Nijenhuis S, Helsen MM, van der Heijden A, Senshu T, van den Berg WB, van Venrooij WJ, Joosten LA
Objective: Antibodies directed to citrulline-containing proteins are highly specific for rheumatoid arthritis (RA) and can be detected in up to 80% of patients with RA. Citrulline is a nonstandard amino acid that can be incorporated into proteins only by posttranslational modification of arginine by peptidylarginine deiminase (PAD) enzymes. The objective of this study was to investigate the presence of anticitrulline antibodies, PAD enzymes, and citrullinated antigens in mouse models of both acu... Abstract
Cited 125 times since 2003 (5.8 per year) source: EuropePMC
Proceedings of the National Academy of Sciences of the United States of America, Volume 100, Issue 19, 28 4 2003, Pages 10989-10994 The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold. Humme S, Reisbach G, Feederle R, Delecluse HJ, Bousset K, Hammerschmidt W, Schepers A
The Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is one of the earliest viral proteins expressed after infection and is the only latent protein consistently expressed in viral-associated tumors. EBNA1's crucial role in viral DNA replication, episomal maintenance, and partitioning is well examined whereas its importance for the immortalization process and the tumorgenicity of EBV is unclear. To address these open questions, we generated, based on the maxi-EBV system, an EBNA1-deficient... Abstract
Cited 116 times since 2003 (5.4 per year) source: EuropePMC
Circulation, Volume 108, Issue 11, 25 4 2003, Pages 1368-1374 Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin. Kleemann R, Princen HM, Emeis JJ, Jukema JW, Fontijn RD, Horrevoets AJ, Kooistra T, Havekes LM
Background: Statins can exert anti-inflammatory antiatherosclerotic effects through an anti-inflammatory action, independent of lowering cholesterol. We addressed the question whether the anti-inflammatory activities of statins can reduce atherosclerosis beyond the reduction achieved by cholesterol lowering per se. Methods and results: Two groups of 20 female APOE*3-Leiden mice received either a high-cholesterol diet (HC) or a high-cholesterol diet supplemented with 0.005% (wt/wt) rosuvastatin (... Abstract
Cited 4 times since 2003 (0.2 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 19, Issue 4, 1 1 2003, Pages 259-266 End-diastolic and end-systolic volume from the left ventricular angiogram: how accurate is visual frame selection? Comparison between visual and semi-automated comnputer-assisted analysis. Staal EM, de Heer M, Jukema JW, Koning G, van der Wall EE, Reiber JH, Baan J, Steendijk P
Background: End-diastolic (ED), end-systolic (ES) left ventricular (LV) volumes and LV ejection fraction (LVEF) are important parameters for clinical decision making in heart disease. In clinical practice the frames from cine-angiography with the largest and smallest opacified LV areas are visually selected and the endocardial borders traced as LVED and LVES contours, respectively. We compared the accuracy of this visual method using two frames with a semi-automated computer assisted frame-by-fr... Abstract