9618 results
Cited 61 times since 2004 (2.8 per year)
source: EuropePMC
Pharmacogenetics,
Volume 14, Issue 1, 1 1 2004, Pages 27-33
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
Visser LE, van Vliet M, van Schaik RH, Kasbergen AA, De Smet PA, Vulto AG, Hofman A, van Duijn CM, Stricker BH
Cytochrome P4502C9 (CYP2C9) is the main enzyme implicated in coumarin anticoagulant metabolism. The variant alleles CYP2C9*2 and CYP2C9*3 are associated with an increased response to warfarin. However, an effect on acenocoumarol dose requirements appears to be absent for the CYP2C9*2 allele and the consequences for the metabolism of phenprocoumon have not yet been established. We investigated CYP2C9 polymorphisms in relation to the international normalized ratio (INR) during the first 6 weeks of...
Abstract
Cited 56 times since 2004 (2.6 per year)
source: EuropePMC
Journal of bacteriology,
Volume 186, Issue 2, 1 1 2004, Pages 316-325
The alternative sigma factor sigmaB of Bacillus cereus: response to stress and role in heat adaptation.
van Schaik W, Tempelaars MH, Wouters JA, de Vos WM, Abee T
A gene cluster encoding the alternative sigma factor sigma(B), three predicted regulators of sigma(B) (RsbV, RsbW, and RsbY), and one protein whose function is not known (Orf4) was identified in the genome sequence of the food pathogen Bacillus cereus ATCC 14579. Western blotting with polyclonal antibodies raised against sigma(B) revealed that there was 20.1-fold activation of sigma(B) after a heat shock from 30 to 42 degrees C. Osmotic upshock and ethanol exposure also upregulated sigma(B), alb...
Abstract
Cited 5 times since 2004 (0.2 per year)
source: EuropePMC
The Cochrane database of systematic reviews,
Issue 2, 1 1 2004, Pages CD003456
Drug therapy for chronic idiopathic axonal polyneuropathy.
Vrancken AF, van Schaik IN, Hughes RA, Notermans NC
Background: Chronic idiopathic axonal polyneuropathy is an insidiously progressive sensory or sensorimotor polyneuropathy that affects elderly people. Although severe disability or handicap does not occur, it reduces quality of life. Objectives: To assess whether drug therapy for chronic idiopathic axonal polyneuropathy reduces disability, ameliorates neurological symptoms and associated impairments, and whether treatment is safe. Search strategy: We searched Cochrane Library (Cochrane Neuromusc...
Abstract
Cited 133 times since 2004 (6.1 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 2, 1 1 2004, Pages 96-103
Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery.
Kertai MD, Boersma E, Westerhout CM, van Domburg R, Klein J, Bax JJ, van Urk H, Poldermans D
Purpose: To assess the potential long-term beneficial effects of statin use after successful abdominal aortic surgery. Methods: Between 1991 and 2001, 570 patients underwent abdominal aortic aneurysm repair at the Erasmus Medical Center. Of the 519 patients (91%) who survived surgery beyond 30 days, 510 (98%) were followed for a median of 4.7 years (interquartile range, 2.7 to 7.3 years). These patients were evaluated for use of statins and beta-blockers, and for clinical risk factors (e.g., adv...
Abstract
Cited 104 times since 2004 (4.8 per year)
source: EuropePMC
The American journal of medicine,
Volume 116, Issue 1, 1 1 2004, Pages 8-13
Aortic stenosis: an underestimated risk factor for perioperative complications in patients undergoing noncardiac surgery.
Kertai MD, Bountioukos M, Boersma E, Bax JJ, Thomson IR, Sozzi F, Klein J, Roelandt JR, Poldermans D
Purpose: To determine the incidence of perioperative events in patients with aortic stenosis undergoing noncardiac surgery. Methods: We studied 108 patients with moderate (mean gradient, 25 to 49 mm Hg) or severe (mean gradient, > or =50 mm Hg) aortic stenosis and 216 controls who underwent noncardiac surgery between 1991 and 2000 at Erasmus Medical Center. Controls were selected based on calendar year and type of surgery. Details of clinical risk factors, type of surgery, and perioperative m...
Abstract
Cited 25 times since 2004 (1.2 per year)
source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance,
Volume 6, Issue 4, 1 1 2004, Pages 767-776
Accurate and reproducible mitral valvular blood flow measurement with three-directional velocity-encoded magnetic resonance imaging.
Westenberg JJ, Danilouchkine MG, Doornbos J, Bax JJ, van der Geest RJ, Labadie G, Lamb HJ, Versteegh MI, de Roos A, Reiber JH
A new method for quantifying the transvalvular flow through the mitral valve (MV) based on three-directional velocity-encoded magnetic resonance imaging (MRI) is presented. For thirty time phases during one cardiac cycle, the three-dimensional (3D) velocity vector field of the blood flow is reconstructed from the MRI measurement. Retrospectively, for each time phase, the MV-plane is indicated manually in the velocity data and the flow through this plane is determined, representing the MV flow. M...
Abstract
Cited 11 times since 2004 (0.5 per year)
source: EuropePMC
The American journal of cardiology,
Volume 93, Issue 1, 1 1 2004, Pages 14-17
Incidence of recovery of contractile function following revascularization in patients with ischemic left ventricular dysfunction.
Schinkel AF, Poldermans D, Vanoverschelde JL, Elhendy A, Boersma E, Roelandt JR, Bax JJ
Contractile function in patients with ischemic left ventricular (LV) dysfunction may improve after myocardial revascularization. Currently, the incidence of contractile function recovery after revascularization in these patients is unclear. The aim of this study was to assess the incidence of function improvement after myocardial revascularization in patients with ischemic LV dysfunction. A total of 258 consecutive patients (aged 59 +/- 12 years) with severely depressed LV ejection fractions (EF...
Abstract
Cited 83 times since 2004 (3.8 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 89, Issue 1, 1 1 2004, Pages 71-75
Increased prevalence of regurgitant valvular heart disease in acromegaly.
Pereira AM, van Thiel SW, Lindner JR, Roelfsema F, van der Wall EE, Morreau H, Smit JW, Romijn JA, Bax JJ
Cardiac involvement is common in acromegaly, but the prevalence of valvular abnormalities in patients with acromegaly has not been documented and is the topic of this study. In a prospective study design, 40 consecutive patients with acromegaly and 120 control subjects (matched for age, sex, hypertension, and left ventricular systolic function) were studied. All patients and controls were evaluated using conventional two-dimensional and Doppler echocardiography. Significant valve disease was mor...
Abstract
Cited 23 times since 2004 (1.1 per year)
source: EuropePMC
Anesthesiology,
Volume 100, Issue 1, 1 1 2004, Pages 4-7
Is there any reason to withhold beta blockers from high-risk patients with coronary artery disease during surgery?
Kertai MD, Bax JJ, Klein J, Poldermans D
Abstract
Cited 142 times since 2003 (6.6 per year)
source: EuropePMC
Circulation,
Volume 109, Issue 3, 29 5 2004, Pages 393-398
Toll-like receptor 4 is involved in outward arterial remodeling.
Hollestelle SC, De Vries MR, Van Keulen JK, Schoneveld AH, Vink A, Strijder CF, Van Middelaar BJ, Pasterkamp G, Quax PH, De Kleijn DP
Background: Toll-like receptor 4 (Tlr4) is the receptor for exogenous lipopolysaccharides (LPS). Expression of endogenous Tlr4 ligands, heat shock protein 60 (Hsp60) and extra domain A of fibronectin, has been observed in arthritic and oncological specimens in which matrix turnover is an important feature. In atherosclerosis, outward remodeling is characterized by matrix turnover and a structural change in arterial circumference and is associated with a vulnerable plaque phenotype. Since Tlr4 li...
Abstract
Cited 35 times since 2003 (1.6 per year)
source: EuropePMC
Human molecular genetics,
Volume 13, Issue 3, 8 2 2003, Pages 295-302
Expression of complement components in the peripheral nervous system.
de Jonge RR, van Schaik IN, Vreijling JP, Troost D, Baas F
We have generated a SAGE (serial analysis of gene expression) library of normal sciatic nerve and found tags encoding for mRNAs of the complement system highly represented. RNA (RT-PCR and northern blot hybridization) and protein (western blot analysis and immunohistochemistry) studies confirmed these findings. High expression of classical pathway components, alternative pathway components and inhibitory components was observed in specific regions of the sciatic nerve. The first components of co...
Abstract
Cited 2 times since 2003 (0.1 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 529-531
Viability assessment: nuclear imaging vs. dobutamine echocardiography.
Bax JJ, van der Wall EE
Abstract
Cited 42 times since 2003 (1.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 5, Issue 6, 1 1 2003, Pages 767-774
Screening for left ventricular dysfunction using a hand-carried cardiac ultrasound device.
Vourvouri EC, Schinkel AF, Roelandt JR, Boomsma F, Sianos G, Bountioukos M, Sozzi FB, Rizzello V, Bax JJ, Karvounis HI, Poldermans D
Background: The hand-carried cardiac ultrasound (HCU) device is a recently introduced imaging device, which may be potentially useful in the primary care setting. Aim: To test the screening potential of a HCU for the detection of left ventricular (LV) dysfunction by evaluating LV ejection fraction (LVEF) and inferior vena cava (IVC) collapse. Standard echocardiographic system (SE) and plasma brain natriuretic peptide (BNP) measurements were used as a reference. Methods: Eighty-eight consecutive...
Abstract
Cited 11 times since 2003 (0.5 per year)
source: EuropePMC
Nuklearmedizin. Nuclear medicine,
Volume 42, Issue 6, 1 1 2003, Pages 240-243
Iodine excretion during stimulation with rhTSH in differentiated thyroid carcinoma.
Löffler M, Weckesser M, Franzius C, Kies P, Schober O
Aim: Elevated iodine intake is a serious problem in the diagnostic and therapeutic application of (131)iodine in patients with differentiated thyroid cancer. Therefore, iodine avoidance is necessary 3 months in advance. Additionally, endogenous stimulation requires withdrawal of thyroid hormone substitution for 4 weeks. Exogenous stimulation using recombinant human TSH (rhTSH) enables the continuous substitution of levothyroxine, which contains 65.4% of its molecular weight in iodine. Thus, a su...
Abstract
Cited 5 times since 2003 (0.2 per year)
source: EuropePMC
Lancet (London, England),
Volume 362, Issue 9401, 1 1 2003, Pages 2118-9; author reply 2119-20
Selective decontamination of digestive tract in intensive care.
Bonten MJ, Kluytmans J, de Smet AM, Bootsma M, Hoes A
Abstract
Cited 38 times since 2003 (1.7 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 60, Issue 4, 1 1 2003, Pages 452-457
Randomized study to compare balloon angioplasty and elective stent implantation in venous bypass grafts: the Venestent study.
Hanekamp CE, Koolen JJ, Den Heijer P, Schalij MJ, Piek JJ, Bär FW, De Scheerder I, Bonnier HJ, Pijls NH, Venestent Study Group
The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vesse...
Abstract
The international journal of cardiovascular imaging,
Volume 19, Issue 6, 1 1 2003, Pages 549-552
MR imaging in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
van der Wall EE, Schalij MJ
Abstract
Cited 66 times since 2003 (3 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 126, Issue 6, 1 1 2003, Pages 2003-2010
Decellularization of rat aortic valve allografts reduces leaflet destruction and extracellular matrix remodeling.
Grauss RW, Hazekamp MG, van Vliet S, Gittenberger-de Groot AC, DeRuiter MC
Objectives: Decellularization of aortic valve allografts in advance of transplantation is a promising approach to overcome immune-induced early graft failure. In this study the effects of in vitro cell extraction on extracellular matrix molecules and in vivo remodeling of decellularized aortic valves were investigated in a heterotopic aortic valve rat implantation model. Methods: Rat aortic valve conduits were decellularized by a 2-step detergent-enzymatic extraction method involving sodium dode...
Abstract
Cited 36 times since 2003 (1.7 per year)
source: EuropePMC
Cyberpsychology & behavior : the impact of the Internet, multimedia and virtual reality on behavior and society,
Volume 6, Issue 6, 1 1 2003, Pages 591-611
Developing a virtual reality-based methodology for people with dementia: a feasibility study.
Flynn D, van Schaik P, Blackman T, Femcott C, Hobbs B, Calderon C
The aim of this study was to examine the feasibility of virtual reality (VR) technology for use by persons with dementia (PWD). Data were obtained directly from six PWD regarding their experiences with a virtual environment (VE) of a large outdoor park. A user-centered method was developed to assess: (a) presence; (b) user inputs; (c) display quality; (d) simulation fidelity; and (e) overall system usability. The extent to which PWD could perform four functional activities in the VE was also inv...
Abstract
Cited 29 times since 2003 (1.3 per year)
source: EuropePMC
Journal of virology,
Volume 77, Issue 24, 1 1 2003, Pages 12996-13004
Intra- and intermolecular disulfide bonds of the GP2b glycoprotein of equine arteritis virus: relevance for virus assembly and infectivity.
Wieringa R, De Vries AA, Post SM, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus belonging to the family Arteriviridae of the order NIDOVIRALES: EAV virions contain six different envelope proteins. The glycoprotein GP(5) (previously named G(L)) and the unglycosylated membrane protein M are the major envelope proteins, while the glycoproteins GP(2b) (previously named G(S)), GP(3), and GP(4) are minor structural proteins. The unglycosylated small hydrophobic envelope protein E is present in virus particles...
Abstract
