Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 38 times since 2002 (1.7 per year) source: EuropePMC
Cardiovascular research, Volume 55, Issue 4, 1 1 2002, Pages 768-777 Angiogenesis-independent cardioprotection in FGF-1 transgenic mice. Buehler A, Martire A, Strohm C, Wolfram S, Fernandez B, Palmen M, Wehrens XH, Doevendans PA, Franz WM, Schaper W, Zimmermann R
Objective: This study was performed to evaluate the cardioprotective role of acidic fibroblast growth factor-1 (FGF-1) in transgenic mice with cardiac-specific overexpression of human FGF-1. Methods: Mice were subjected to coronary artery occlusion for 15-75 min with a continuously recorded 3-lead electrocardiogram (ECG). Infarct size was measured and ERK-1 and -2 activity was assessed by Western blot analysis. Creatine kinase and lactate dehydrogenase activity as marker for cell viability were... Abstract
Cited 26 times since 2002 (1.1 per year) source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology, Volume 22, Issue 9, 1 1 2002, Pages 1433-1438 Inhibition of accelerated atherosclerosis in vein grafts by placement of external stent in apoE*3-Leiden transgenic mice. Lardenoye JH, De Vries MR, Grimbergen JM, Havekes LM, Knaapen MW, Kockx MM, van Hinsbergh VW, van Bockel JH, Quax PH
Objective: Vein grafts fail because of the development of intimal hyperplasia and accelerated atherosclerosis. Placement of an external stent around vein grafts resulted in an inhibition of intimal hyperplasia in several animal studies. Here, we assess the effects of external stenting on accelerated atherosclerosis in early vein grafts in carotid arteries in hypercholesterolemic apolipoprotein E*3-Leiden transgenic mice. Methods and results: Venous interposition grafting was performed in apolipo... Abstract
Cited 20 times since 2002 (0.9 per year) source: EuropePMC
Diabetes care, Volume 25, Issue 9, 1 1 2002, Pages 1637-1643 Prognostic value of dobutamine-atropine stress myocardial perfusion imaging in patients with diabetes. Schinkel AF, Elhendy A, van Domburg RT, Bax JJ, Vourvouri EC, Sozzi FB, Valkema R, Roelandt JR, Poldermans D
Objective: Exercise tolerance in patients with diabetes is frequently impaired due to noncardiac disease such as claudication and polyneuropathy. This study assesses the prognostic value of dobutamine stress myocardial perfusion imaging in patients with diabetes. Research design and methods: A total of 207 consecutive diabetic patients who were unable to undergo exercise stress testing underwent dobutamine-atropine stress myocardial perfusion imaging. Follow-up was successful in 206 of 207 (99.5... Abstract
Cited 234 times since 2002 (10.2 per year) source: EuropePMC
Circulation, Volume 106, Issue 13, 1 1 2002, Pages 1703-1707 Magnetic resonance imaging to assess the hemodynamic effects of pulmonary valve replacement in adults late after repair of tetralogy of fallot. Vliegen HW, van Straten A, de Roos A, Roest AA, Schoof PH, Zwinderman AH, Ottenkamp J, van der Wall EE, Hazekamp MG
Background: Pulmonary regurgitation (PR) late after total correction for tetralogy of Fallot may lead to progressive right ventricular (RV) dilatation and an increased incidence of severe arrhythmias and sudden death. Timing of pulmonary valve replacement (PVR) is subject to discussion, because the effect of PVR on RV function in adults is unclear. In this study, MRI was used to assess the effect of PVR on RV function and PR. Clinical improvement was established by means of the NYHA classificati... Abstract
Cited 19 times since 2002 (0.8 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 22, Issue 3, 1 1 2002, Pages 426-430 The beneficial effect of revascularization on jeopardized myocardium: reverse remodeling and improved long-term prognosis. Mule JD, Bax JJ, Zingone B, Martinelli F, Burelli C, Stefania A, DiSipio L, Soravia G
Objectives: To evaluate the impact of viability/ischemia before revascularization on improvement in systolic performance, reverse remodeling, symptoms and long-term prognosis post-revascularization. Methods: Fifty patients underwent thallium-201 imaging before revascularization to assess stress-induced ischemia and viability ('jeopardized myocardium'). Left ventricular (LV) ejection fraction (EF), LV end-systolic volume index (LVESVI) and LV end-diastolic volume index (LVEDVI) were det... Abstract
Cited 1 times since 2002 (0 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 10, Issue 9, 1 1 2002, Pages 345-348 Adults with congenital heart disease: a growing population. Vriend JW, van der Velde ET, Mulder BJ
Cited 7 times since 2002 (0.3 per year) source: EuropePMC
Circulation, Volume 106, Issue 12 Suppl 1, 1 1 2002, Pages I14-8 Perfusion and contractile reserve in chronic dysfunctional myocardium: relation to functional outcome after surgical revascularization. Bax JJ, Poldermans D, Schinkel AF, Boersma E, Elhendy A, Maat A, Valkema R, Krenning EP, Roelandt JR
Background: Chronic dysfunctional but viable myocardium may exhibit contractile reserve and/or intact perfusion. Segments with intact perfusion without contractile reserve are frequently observed inpatients with ischemic cardiomyopathy. The clinical relevance of this observation is unclear; in particular, the functional outcome after revascularization is unknown. Thus, contractile reserve (using low-dose dobutamine echocardiography) and perfusion (using resting (99m)Tc tetrofosmin) were evaluate... Abstract
Cited 28 times since 2002 (1.2 per year) source: EuropePMC
British journal of cancer, Volume 87, Issue 6, 1 1 2002, Pages 659-664 Secreted and tumour targeted human carboxylesterase for activation of irinotecan. Oosterhoff D, Pinedo HM, van der Meulen IH, de Graaf M, Sone T, Kruyt FA, van Beusechem VW, Haisma HJ, Gerritsen WR
Irinotecan (CPT-11) is an anticancer agent for the treatment of colon cancer. CPT-11 can be considered as a prodrug, since it needs to be activated into the toxic drug SN-38 by the enzyme carboxylesterase. An approach to achieve tumour specific activation of CPT-11 is to transduce the cDNA encoding carboxylesterase into tumour cells. A secreted form of carboxylesterase may diffuse through a tumour mass and may activate CPT-11 extracellularly. This could enhance the antitumour efficacy by exertin... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 10, Issue 7-8, 1 1 2002, Pages 329-330 Contrast medium echocardiography-assisted pericardiocentesis of loculated pericardial fluid. van Houwelingen KG, Bax JJ, Jukema JW, van der Wall EE
Cited 1 times since 2002 (0 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 10, Issue 7-8, 1 1 2002, Pages 301-303 100 years of electrocardiography; who was Willem Einthoven? (1860-1927). Schalij MJ, van der Wall EE
Cited 14 times since 2002 (0.6 per year) source: EuropePMC
The Journal of laryngology and otology, Volume 116, Issue 8, 1 1 2002, Pages 622-626 Assessment of patency of the internal jugular vein following neck dissection and microvascular flap reconstruction by power Doppler ultrasound. de Bree R, van den Berg FG, van Schaik C, Beerens AJ, Manoliu RA, Castelijns JA, Snow GB, Leemans CR
The objective of this study was to assess patency of the internal jugular vein following modified radical or selective neck dissection and microvascular flap reconstruction by power Doppler ultrasound and its impact on free flap survival. In 23 patients who underwent selective or modified radical neck dissection and microvascular flap reconstruction the patency of the internal jugular vein was examined by power Doppler ultrasound on the first post-operative day and after follow-up of at least fo... Abstract
Cited 42 times since 2002 (1.8 per year) source: EuropePMC
The American journal of cardiology, Volume 90, Issue 4, 1 1 2002, Pages 379-383 Effectiveness of resynchronization therapy in patients with end-stage heart failure. Molhoek SG, Bax JJ, van Erven L, Bootsma M, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
Biventricular pacing has been introduced to treat patients with end-stage heart failure, and short-term results of this technique are promising. Because data on longer follow-up are limited to 3-month follow-up, the sustained effect of biventricular pacing is unclear and long-term survival is unknown. Forty patients with end-stage heart failure in New York Heart Association (NYHA) functional class III or IV with left ventricular (LV) ejection fraction (EF) 120 ms, and left bundle branch block mo... Abstract
Cited 62 times since 2002 (2.7 per year) source: EuropePMC
American heart journal, Volume 144, Issue 2, 1 1 2002, Pages 198-205 Assessment of diastolic function by cardiovascular magnetic resonance. Paelinck BP, Lamb HJ, Bax JJ, Van der Wall EE, de Roos A
Background: The assessment of diastolic heart function has been hampered by multiple difficulties. Cardiovascular magnetic resonance (CMR) is a new, noninvasive technique to study cardiac function. Methods: The literature on CMR for the analysis of diastolic function and its clinical applications is extensively reviewed. Results: Analysis of ventricular filling velocity and volume flow, volumetric assessment of ventricular chamber volume, analysis of 3-dimensional myocardial strains, and assessm... Abstract
Cited 43 times since 2002 (1.9 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 29, Issue 9, 11 2 2002, Pages 1257-1266 The need for standardisation of cardiac FDG PET imaging in the evaluation of myocardial viability in patients with chronic ischaemic left ventricular dysfunction. Knuuti J, Schelbert HR, Bax JJ
The evaluation of myocardial glucose utilisation with fluorine-18 fluorodeoxyglucose (FDG) and positron emission tomography is currently considered the most reliable tool for the identification of myocardial viability. However, the investigations using FDG imaging to predict improvement in left ventricular (LV) function after revascularisation have reported wide ranges for sensitivity (71%-100%) and, in particular, for specificity (33%-91%). The variable results may be related to differences in... Abstract
Cited 48 times since 2002 (2.1 per year) source: EuropePMC
Journal of vascular surgery, Volume 36, Issue 1, 1 1 2002, Pages 94-99 The impact of walking impairment, cardiovascular risk factors, and comorbidity on quality of life in patients with intermittent claudication. Breek JC, Hamming JF, De Vries J, van Berge Henegouwen DP, van Heck GL
Objective: The objective of this study was to assess the impact of walking impairment, cardiovascular risk factors, and comorbidity on quality of life (QOL) in patients with intermittent claudication (IC). Material and methods: The prospective observational study was conducted in the setting of a vascular outpatient department of a teaching hospital. QOL was assessed in 200 consecutive patients with IC, with a reduced version of the World Health Organization Quality of Life Assessment Instrument... Abstract
Cited 5 times since 2002 (0.2 per year) source: EuropePMC
Immunology, Volume 106, Issue 3, 1 1 2002, Pages 336-342 Cross-reactivity of the anti-La monoclonal antibody SW5 with early endosome antigen 2. Fouraux MA, van der Heijden A, van Venrooij WJ, Pruijn GJ
Coimmunoprecipitation studies with SW5, a frequently used and specific mouse monoclonal antibody (mAb) directed against the human La autoantigen, led to the identification of a functionally unrelated 80 000 MW protein, designated early endosome antigen 2 (EEA2). EEA2 appeared to be directly targeted by mAb SW5. Because an RNA-binding domain, a structural element of La containing the SW5-epitope, was not discernable in the primary structure of EEA2, the SW5-epitope on EEA2 was determined. Coiled-... Abstract
Cited 29 times since 2002 (1.3 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 22, Issue 1, 1 1 2002, Pages 70-77 Report of the Dutch experience with the Ross procedure in 343 patients. Takkenberg JJ, Dossche KM, Hazekamp MG, Nijveld A, Jansen EW, Waterbolk TW, Bogers AJ, Dutch Ross Study Group
Objective: Limited information is available on outcome after autograft aortic valve replacement, in particular with respect to the durability of the autograft and of the allograft used to reconstruct the right ventricular outflow tract. A retrospective follow-up study of all patients who underwent a Ross procedure in the Netherlands since 1988 was done to obtain an overview of the Dutch experience with this procedure. Methods: From 1988 to January 2000, 348 Ross procedures were performed in nine... Abstract
Cited 64 times since 2002 (2.8 per year) source: EuropePMC
Preventive veterinary medicine, Volume 54, Issue 3, 1 1 2002, Pages 279-289 Probability of and risk factors for introduction of infectious diseases into Dutch SPF dairy farms: a cohort study. van Schaik G, Schukken YH, Nielen M, Dijkhuizen AA, Barkema HW, Benedictus G
A 2-year cohort study was conducted to investigate the probability of disease introduction into Dutch dairy farms. The farms were tested regularly for diseases and were visited biannually to collect management data. Ninety-five specific pathogen-free (SPF) dairy farms were selected from a database of bovine herpesvirus type 1 (BHV1)-free farms to study the probability of, and risk factors for, introduction of BHV1, bovine viral diarrhoea virus (BVDV), Salmonella enterica subsp. enterica serotype... Abstract
Cited 76 times since 2002 (3.3 per year) source: EuropePMC
Applied and environmental microbiology, Volume 68, Issue 7, 1 1 2002, Pages 3486-3495 Identification of proteins involved in the heat stress response of Bacillus cereus ATCC 14579. Periago PM, van Schaik W, Abee T, Wouters JA
To monitor the ability of the food-borne opportunistic pathogen Bacillus cereus to survive during minimal processing of food products, we determined its heat-adaptive response. During pre-exposure to 42 degrees C, B. cereus ATCC 14579 adapts to heat exposure at the lethal temperature of 50 degrees C (maximum protection occurs after 15 min to 1 h of pre-exposure to 42 degrees C). For this heat-adaptive response, de novo protein synthesis is required. By using two-dimensional gel electrophoresis,... Abstract
Heart (British Cardiac Society), Volume 88, Issue 1, 1 1 2002, Pages 60 Images in cardiology: Myocardial infarction and coronary thrombosis. Lindeboom JE, Shahin GM, Bosker HA