Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6131 results
Cited 18 times since 2012 (1.4 per year) source: EuropePMC
Atherosclerosis, Volume 221, Issue 2, 1 1 2012, Pages 333-340 Annexin A5 prevents post-interventional accelerated atherosclerosis development in a dose-dependent fashion in mice. Ewing MM, Karper JC, Sampietro ML, de Vries MR, Pettersson K, Jukema JW, Quax PH
Background: Activated cells in atherosclerotic lesions expose phosphatidylserine (PS) on their surface. Annexin A5 (AnxA5) binds to PS and is used for imaging atherosclerotic lesions. Recently, AnxA5 was shown to inhibit vascular inflammatory processes after vein grafting. Here, we report a therapeutic role for AnxA5 in post-interventional vascular remodeling in a mouse model mimicking percutaneous coronary intervention (PCI). Methods and results: Associations between the rs4833229 (OR = 1.29 (C... Abstract
Cited 16 times since 2012 (1.2 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 20, Issue 2, 1 1 2012, Pages 53-65 Remote monitoring and follow-up of cardiovascular implantable electronic devices in the Netherlands : An expert consensus report of the Netherlands Society of Cardiology. de Cock CC, Elders J, van Hemel NM, van den Broek K, van Erven L, de Mol B, Talmon J, Theuns DA, de Voogt W
Remote monitoring of cardiac implanted electronic devices (CIED: pacemaker, cardiac resynchronisation therapy device and implantable cardioverter defibrillator) has been developed for technical control and follow-up using transtelephonic data transmission. In addition, automatic or patient-triggered alerts are sent to the cardiologist or allied professional who can respond if necessary with various interventions. The advantage of remote monitoring appears obvious in impending CIED failures and s... Abstract
Cited 18 times since 2012 (1.4 per year) source: EuropePMC
Journal of cellular and molecular medicine, Volume 16, Issue 2, 1 1 2012, Pages 328-336 A limited role for regulatory T cells in post-ischemic neovascularization. Hellingman AA, van der Vlugt LE, Lijkwan MA, Bastiaansen AJ, Sparwasser T, Smits HH, Hamming JF, Quax PH
Recently, it was demonstrated that arteriogenesis is enhanced in mice deficient in regulatory T cells (CD4(+) CD25(+) FoxP3(+) T cell), which can suppress effector T cell responses. The present study investigates the effects of these regulatory T cells on arteriogenesis in more detail by either specific expanding or depleting regulatory T cells. Hind limb ischemia was induced by electro-coagulation of the femoral artery in mice. Regulatory T cells were either expanded by injecting mice with a c... Abstract
Cited 7 times since 2012 (0.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 20, Issue 2, 1 1 2012, Pages 66-70 Integration of data from remote monitoring systems and programmers into the hospital electronic health record system based on international standards. van der Velde ET, Foeken H, Witteman TA, van Erven L, Schalij MJ
Remote follow-up of implanted ICDs may offer a solution to the problem of overcrowded outpatient clinics. All major device companies have developed a remote follow-up solution. Data obtained from the remote follow-up systems are stored in a central database system, operated and owned by the device company and accessible for the physician or technician. However, the problem now arises that part of the patient's clinical information is stored in the local electronic health record (EHR) system... Abstract
Cited 6 times since 2012 (0.5 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 98, Issue 4, 1 1 2012, Pages 335-341 How to reduce sudden cardiac death in patients with renal failure. de Bie MK, Buiten MS, Rabelink TJ, Jukema JW
Cited 31 times since 2012 (2.4 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 93, Issue 3, 31 5 2012, Pages 754-760 Changes in left ventricular function after mitral valve repair for severe organic mitral regurgitation. Witkowski TG, Thomas JD, Delgado V, van Rijnsoever E, Ng AC, Hoke U, Ewe SH, Auger D, Yiu KH, Holman ER, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA
Background: Limited data are available on the changes in left ventricular (LV) contractile function at long-term follow-up after mitral valve repair (MVr). Moreover, assessment of LV systolic function in patients undergoing MVr is troublesome with current methods, given that mitral regurgitation is characterized by increased preload and decreased afterload, potentially masking LV dysfunction. The aim of this study was to assess the value of LV global strain (longitudinal and circumferential) mea... Abstract
Cited 3 times since 2012 (0.2 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 42, Issue 1, 26 4 2012, Pages 50-55 Effect of age on exercise capacity and cardiac reserve in patients with pulmonary atresia with intact ventricular septum after biventricular repair. Romeih S, Groenink M, van der Plas MN, Spijkerboer AM, Hazekamp MG, Luijnenburg S, Mulder BJ, Blom NA
Objectives: In patients with pulmonary atresia with intact ventricular septum (PAIVS), biventricular repair is considered to be the optimal treatment option in the absence of significant right ventricular (RV) hypoplasia. However, long-term clinical outcome studies are limited. We evaluated exercise capacity and cardiac function during pharmacological stress in children and young adults with PAIVS after biventricular repair. Methods: Ten PAIVS patients after biventricular repair, with a median a... Abstract
Cited 111 times since 2012 (8.5 per year) source: EuropePMC
European heart journal, Volume 33, Issue 8, 26 4 2012, Pages 1007-1016 Automated quantification of coronary plaque with computed tomography: comparison with intravascular ultrasound using a dedicated registration algorithm for fusion-based quantification. Boogers MJ, Broersen A, van Velzen JE, de Graaf FR, El-Naggar HM, Kitslaar PH, Dijkstra J, Delgado V, Boersma E, de Roos A, Schuijf JD, Schalij MJ, Reiber JH, Bax JJ, Jukema JW
Aims: Previous studies have used semi-automated approaches for coronary plaque quantification on multi-detector row computed tomography (CT), while an automated quantitative approach using a dedicated registration algorithm is currently lacking. Accordingly, the study aimed to demonstrate the feasibility and accuracy of automated coronary plaque quantification on cardiac CT using dedicated software with a novel 3D coregistration algorithm of CT and intravascular ultrasound (IVUS) data sets. Meth... Abstract
Cited 6 times since 2012 (0.5 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 28, Issue 8, 24 4 2012, Pages 2065-2071 Non-invasive assessment of atherosclerotic coronary lesion length using multidetector computed tomography angiography: comparison to quantitative coronary angiography. van Velzen JE, de Graaf MA, Ciarka A, de Graaf FR, Schalij MJ, Kroft LJ, de Roos A, Jukema JW, Reiber JH, Schuijf JD, Bax JJ, van der Wall EE
Multidetector computed tomography angiography (CTA) provides information on plaque extent and stenosis in the coronary wall. More accurate lesion assessment may be feasible with CTA as compared to invasive coronary angiography (ICA). Accordingly, lesion length assessment was compared between ICA and CTA in patients referred for CTA who underwent subsequent percutaneous coronary intervention (PCI). 89 patients clinically referred for CTA were subsequently referred for ICA and PCI. On CTA, lesion... Abstract
Cited 25 times since 2012 (1.9 per year) source: EuropePMC
European heart journal, Volume 33, Issue 7, 24 4 2012, Pages 913-920 Effect of cardiac resynchronization therapy in patients without left intraventricular dyssynchrony. Auger D, Bleeker GB, Bertini M, Ewe SH, van Bommel RJ, Witkowski TG, Ng AC, van Erven L, Schalij MJ, Bax JJ, Delgado V
Aims: To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical dyssynchrony. Methods and results: A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV dyssynchrony ( Abstract
Cited 17 times since 2012 (1.3 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 93, Issue 3, 23 4 2012, Pages 849-855 Long-term results of reoperation for left atrioventricular valve regurgitation after correction of atrioventricular septal defects. Hoohenkerk GJ, Bruggemans EF, Koolbergen DR, Rijlaarsdam ME, Hazekamp MG
Background: Long-term results of reoperation for left atrioventricular valve regurgitation (LAVVR) after previous correction of atrioventricular septal defect (AVSD) are scarce. We evaluated long-term outcome of reoperation for LAVVR and identified risk factors for reoperation. Methods: Between December 1976 and July 2006, 45 of 312 patients with correction of different AVSDs underwent reoperation for LAVVR. The cohort of 267 patients who did not need reoperation for LAVVR allowed for the identi... Abstract
Cited 10 times since 2012 (0.8 per year) source: EuropePMC
European heart journal, Volume 33, Issue 15, 22 4 2012, Pages 1934-1941 Predictors of long-term benefit of cardiac resynchronization therapy in patients with right bundle branch block. Leong DP, Höke U, Delgado V, Auger D, Thijssen J, van Erven L, Bax JJ, Schalij MJ, Marsan NA
Aims: The aims of this study were: (i) to characterize consecutive cardiac resynchronization therapy (CRT) recipients with right bundle branch block (RBBB) in comparison with left bundle branch block (LBBB) and (ii) to identify independent predictors of long-term outcome among CRT recipients with RBBB. The presence of RBBB has been associated with poorer prognosis after CRT compared with LBBB; however, little is known about the differences in cardiac mechanics between RBBB and LBBB patients. Fur... Abstract
Cited 8 times since 2012 (0.6 per year) source: EuropePMC
Journal of electrocardiology, Volume 45, Issue 3, 20 3 2012, Pages 312-318 Diagnosis and mortality prediction in pulmonary hypertension: the value of the electrocardiogram-derived ventricular gradient. Scherptong RW, Henkens IR, Kapel GF, Swenne CA, van Kralingen KW, Huisman MV, Schuerwegh AJ, Bax JJ, van der Wall EE, Schalij MJ, Vliegen HW
Purpose: The aim of this study was to investigate the use of the electrocardiogram-derived ventricular gradient, projected on the x-axis (VGx), for detection of pulmonary hypertension (PH) and for prediction of all-cause mortality in PH patients. Methods: In patients referred for PH screening (n = 216), the VGx was calculated semiautomatically from the electrocardiogram and was defined as abnormal when less than 24 mV · ms. The VGx of PH patients was compared with the VGx of patients without PH.... Abstract
Cited 170 times since 2012 (12.9 per year) source: EuropePMC
Cardiovascular research, Volume 94, Issue 2, 20 3 2012, Pages 276-283 The innate immune response in reperfused myocardium. Timmers L, Pasterkamp G, de Hoog VC, Arslan F, Appelman Y, de Kleijn DP
One of the major therapeutic challenges in the arena of interventional cardiology is to design strategies aimed at reducing myocardial tissue damage after myocardial infarction. In response to tissue injury, an innate immune response is initiated that orchestrates homeostatic responses and is a prerequisite for subsequent wound healing. An exaggerated inflammatory reaction, however, countervenes these beneficial effects and contributes to maladaptive tissue damage. Herein, we discuss the pathway... Abstract
Cited 4 times since 2012 (0.3 per year) source: EuropePMC
Acta anaesthesiologica Scandinavica, Volume 56, Issue 4, 19 3 2012, Pages 449-458 Xenon is not superior to isoflurane on cardiovascular function during experimental acute pulmonary hypertension. Roehl AB, Steendijk P, Rossaint R, Bleilevens C, Goetzenich A, Hein M
Background: Acute right ventricular afterload increase is a known perioperative challenge for the anaesthetic regime especially for patients with a compromised right ventricle. The accused negative inotropic action of volatile anaesthetics, with the exception of xenon, might be crucial for the adaptation of the right ventricle. Methods: Reversible pulmonary hypertension (mean pressure 40 mmHg) was induced by an infusion of the stable thromboxane A(2) analog U46619 in a porcine model (n = 35). Th... Abstract
Pacing and clinical electrophysiology : PACE, Volume 35, Issue 7, 16 3 2012, Pages 884-886 Single and inappropriate shock delivered out of tachycardia: device dysfunction? Fontenla A, Carrero D, Salguero R, López-Gil M, De Riva M, Arribas F
The Journal of thoracic and cardiovascular surgery, Volume 144, Issue 2, 11 2 2012, Pages 506-508 Surgical treatment of residual systolic anterior motion after otherwise successful percutaneous transluminal septal myocardial ablation: a case report. Hjortnaes J, Leemans PA, ten Cate FJ, van Herwerden LA
Cited 103 times since 2012 (7.8 per year) source: EuropePMC
The Journal of clinical endocrinology and metabolism, Volume 97, Issue 3, 11 2 2012, Pages 852-861 Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Nanchen D, Gussekloo J, Westendorp RG, Stott DJ, Jukema JW, Trompet S, Ford I, Welsh P, Sattar N, Macfarlane PW, Mooijaart SP, Rodondi N, de Craen AJ, PROSPER Group
Context: Subclinical thyroid dysfunction is common in older people. However, its clinical importance is uncertain. Objective: Our objective was to determine the extent to which subclinical hyperthyroidism and hypothyroidism influence the risk of heart failure and cardiovascular diseases in older people. Setting and design: The Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) is an prospective cohort study. Patients: Patients included men and women aged 70-82 yr (n=5316) with kno... Abstract
Cited 31 times since 2012 (2.4 per year) source: EuropePMC
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, Volume 14, 9 2 2012, Pages 2 Bramwell-Hill modeling for local aortic pulse wave velocity estimation: a validation study with velocity-encoded cardiovascular magnetic resonance and invasive pressure assessment. Westenberg JJ, van Poelgeest EP, Steendijk P, Grotenhuis HB, Jukema JW, de Roos A
Background: The Bramwell-Hill model describes the relation between vascular wall stiffness expressed in aortic distensibility and the pulse wave velocity (PWV), which is the propagation speed of the systolic pressure wave through the aorta. The main objective of this study was to test the validity of this model locally in the aorta by using PWV-assessments based on in-plane velocity-encoded cardiovascular magnetic resonance (CMR), with invasive pressure measurements serving as the gold standard.... Abstract
European heart journal. Cardiovascular Imaging, Volume 13, Issue 6, 9 2 2012, Pages 535 Isolated posterior mitral leaflet cleft resembling trileaflet valve. Vignalou JB, Ewe SH, Schalij MJ, Bax JJ, Delgado V