6128 results
Cited 36 times since 2008 (2.2 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 29, Issue 2, 18 3 2008, Pages 188-194
Leukocyte cathepsin S is a potent regulator of both cell and matrix turnover in advanced atherosclerosis.
de Nooijer R, Bot I, von der Thüsen JH, Leeuwenburgh MA, Overkleeft HS, Kraaijeveld AO, Dorland R, van Santbrink PJ, van Heiningen SH, Westra MM, Kovanen PT, Jukema JW, van der Wall EE, van Berkel TJ, Shi GP, Biessen EA
Objective: A dysbalance of proteases and their inhibitors is instrumental in remodeling of atherosclerotic plaques. One of the proteases implicated in matrix degradation is cathepsin-S (CatS). To address its role in advanced lesion composition, we generated chimeric LDLr(-/-) mice deficient in leukocyte CatS by transplantation with CatS(-/-)xLDLr(-/-) or with LDLr(-/-) bone marrow and administered a high-fat diet. Methods and results: No difference in aortic root lesion size could be detected be...
Abstract
Cited 3 times since 2008 (0.2 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 20, Issue 5, 17 3 2008, Pages 536-538
Should the left ventricular pacing lead be positioned at the site of latest mechanical activation in cardiac resynchronization therapy?
Van Bommel RJ, Schalij MJ, Bax JJ
Abstract
Cited 36 times since 2008 (2.2 per year)
source: EuropePMC
Heart rhythm,
Volume 6, Issue 3, 13 2 2008, Pages 305-310
Clinical importance of new-onset atrial fibrillation after cardiac resynchronization therapy.
Borleffs CJ, Ypenburg C, van Bommel RJ, Delgado V, van Erven L, Schalij MJ, Bax JJ
Background: Data on the occurrence and implications of new-onset atrial fibrillation (AF) following cardiac resynchronization therapy (CRT) are scarce. We studied the incidence of new onset AF in CRT-defibrillator (CRT-D) recipients. The influence of new-onset AF on echocardiographic response to CRT and the rate of adverse events also were evaluated. Objective: The purpose of this study was to assess the incidence and implications of new-onset AF following CRT. Methods: The study population cons...
Abstract
Cited 3 times since 2008 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 25, Issue 2, 5 1 2008, Pages 141-144
Atherosclerotic plaque imaging by PET/CT; can inactive, active and mixed plaques be discerned?
van der Wall EE, Schuijf JD, Jukema JW, Bax JJ, van der Laarse A
Abstract
Cited 2 times since 2008 (0.1 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 296, Issue 2, 5 1 2008, Pages H342-9
Cardiac phase-dependent time normalization reduces load dependence of time-varying elastance.
Kind T, Westerhof N, Faes TJ, Lankhaar JW, Steendijk P, Vonk-Noordegraaf A
The time-varying elastance concept provides a comprehensive description of the intrinsic mechanical properties of the left ventricle that are assumed to be load independent. Based on pressure-volume measurements obtained with combined pressure conductance catheterization in six open-chest anesthetized sheep, we show that the time to reach end systole (defined as maximal elastance) is progressively prolonged for increasing ventricle pressures, which challenges the original (load-independent) time...
Abstract
Cited 21 times since 2008 (1.3 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 36, Issue 4, 3 1 2008, Pages 594-601
Agreement and disagreement between contrast-enhanced magnetic resonance imaging and nuclear imaging for assessment of myocardial viability.
Roes SD, Kaandorp TA, Marsan NA, Westenberg JJ, Dibbets-Schneider P, Stokkel MP, Lamb HJ, van der Wall EE, de Roos A, Bax JJ
Purpose: The purpose of this study was to compare contrast-enhanced MRI and nuclear imaging with (99m)Tc-tetrofosmin and (18)F-fluorodeoxyglucose ((18)F-FDG) single photon emission computed tomography (SPECT) for assessment of myocardial viability. Methods: Included in the study were 60 patients with severe ischaemic left ventricular (LV) dysfunction who underwent contrast-enhanced MRI, (99m)Tc-tetrofosmin and (18)F-FDG SPECT. Myocardial segments were assigned a wall motion score from 0 (normoki...
Abstract
Cited 24 times since 2008 (1.5 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 31, Issue 12, 1 1 2008, Pages 1628-1639
Noninvasive imaging in cardiac resynchronization therapy--Part 2: Follow-up and optimization of settings.
Ypenburg C, Van De Veire N, Westenberg JJ, Bleeker GB, Marsan NA, Henneman MM, Van Der Wall EE, Schalij MJ, Abraham TP, Barold SS, Bax JJ
Cardiac resynchronization therapy (CRT) has become a therapeutic option for drug-refractory heart failure. Several noninvasive imaging techniques play an increasingly important role before and after device implantation. This review highlights the acute and long-term CRT benefits after implantation as assessed with echocardiography and nuclear imaging. Furthermore, optimization of CRT settings, in particular atrioventricular and interventricular delay, will be discussed using echocardiography and...
Abstract
Cited 672 times since 2008 (41.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 52, Issue 25, 1 1 2008, Pages 2135-2144
Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study.
Meijboom WB, Meijs MF, Schuijf JD, Cramer MJ, Mollet NR, van Mieghem CA, Nieman K, van Werkhoven JM, Pundziute G, Weustink AC, de Vos AM, Pugliese F, Rensing B, Jukema JW, Bax JJ, Prokop M, Doevendans PA, Hunink MG, Krestin GP, de Feyter PJ
Objectives: This study sought to determine the diagnostic accuracy of 64-slice computed tomographic coronary angiography (CTCA) to detect or rule out significant coronary artery disease (CAD). Background: CTCA is emerging as a noninvasive technique to detect coronary atherosclerosis. Methods: We conducted a prospective, multicenter, multivendor study involving 360 symptomatic patients with acute and stable anginal syndromes who were between 50 and 70 years of age and were referred for diagnostic...
Abstract
Cited 4 times since 2008 (0.2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 94, Issue 12, 1 1 2008, Pages 1656-1662
Statins: established indications and controversial subgroups.
Jukema JW, Bergheanu SC
Abstract
Cited 59 times since 2008 (3.6 per year)
source: EuropePMC
The Journal of general virology,
Volume 89, Issue Pt 12, 1 1 2008, Pages 2933-2942
Evolutionary dynamics of human and avian metapneumoviruses.
de Graaf M, Osterhaus ADME, Fouchier RAM, Holmes EC
Human (HMPV) and avian (AMPV) metapneumoviruses are closely related viruses that cause respiratory tract illnesses in humans and birds, respectively. Although HMPV was first discovered in 2001, retrospective studies have shown that HMPV has been circulating in humans for at least 50 years. AMPV was first isolated in the 1970s, and can be classified into four subgroups, A-D. AMPV subgroup C is more closely related to HMPV than to any other AMPV subgroup, suggesting that HMPV has emerged from AMPV...
Abstract
Journal of the American College of Cardiology,
Volume 52, Issue 24, 1 1 2008, Pages 2032-2042
Highlights of the 2008 Scientific Sessions of the European Society of Cardiology Munich, Germany, August 30 to September 3, 2008.
Kristensen SD, Baumgartner H, Casadei B, Drexler H, Eeckhout E, Filippatos G, Fox KA, Perk J, Pierard LA, Poldermans D, Schunkert H, Vardas PE, van der Wall EE, Fox K, Bax JJ
Abstract
Clinical nuclear medicine,
Volume 33, Issue 12, 1 1 2008, Pages 852-855
Comparison of outcome after myocardial infarction in patients with and without abnormalities on previous stress Tc-99m tetrofosmin myocardial perfusion imaging.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Feringa HH, Noordzij PG, Schouten O, Karagiannis SE, Dunkelgrun M, Poldermans D
Background: Acute myocardial infarction (MI) can occur in patients with previously normal stress myocardial perfusion imaging (MPI). It is not known whether the prognosis of these patients differ from those with MI who had an abnormal MPI on an earlier testing. The aim of this study was to compare the outcome of patients who sustained a MI during follow-up after stress MPI based on the presence or absence of perfusion abnormalities on the earlier test. Methods: We studied 109 patients (age 62 +/...
Abstract
Cited 132 times since 2008 (8.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 95, Issue 9, 26 4 2008, Pages 715-720
Risk factors and time delay associated with cardiac device infections: Leiden device registry.
Lekkerkerker JC, van Nieuwkoop C, Trines SA, van der Bom JG, Bernards A, van de Velde ET, Bootsma M, Zeppenfeld K, Jukema JW, Borleffs JW, Schalij MJ, van Erven L
Aims: A nested case-control study of 75 patients with cardiac device infections (CDI) and 75 matched controls was conducted to evaluate time course, risk factors, culture results and frequency of CDI. Methods and results: CDI occurred in 75/3410 (2.2%) device implantation and revision procedures, performed between 2000 and 2007. The time delay between device procedure and infection ranged from 0 to 64 months (mean 14 (SD 16)), 21 patients (28%) had an early infection (12 months). Of interest, 18...
Abstract
Cited 23 times since 2008 (1.4 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 49, Issue 2, 22 4 2008, Pages 435-41; discussion 441-2
Plasma N-terminal pro-B-type natriuretic peptide as a predictor of perioperative and long-term outcome after vascular surgery.
Schouten O, Hoeks SE, Goei D, Bax JJ, Verhagen HJ, Poldermans D
Objective: N-terminal pro-B-type natriuretic peptide (NT-proBNP) is secreted by the heart in response to ventricular wall stress and has prognostic value in patients with heart failure, coronary artery disease, and heart valve abnormalities. Postoperative and long-term outcome is also related to these risk factors. This study assessed the additional prognostic value of NT-proBNP levels as a simple objective risk marker for postoperative cardiac events among vascular surgery patients. Methods: A...
Abstract
Cited 8 times since 2008 (0.5 per year)
source: EuropePMC
Diabetologia,
Volume 52, Issue 2, 22 4 2008, Pages 235-239
Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly.
Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, de Craen AJ, Ford I, Forouhi NG, Freeman DJ, Jukema JW, Macfarlane PW, Murphy MB, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Prospective Study of Pravastatin in Elderly at Risk Trial Study Group
Aims/hypothesis: The aim of this prospective study was to determine whether circulating intercellular adhesion molecule (ICAM) 1, as a potential surrogate of 'endothelial activation', is more strongly associated with risk of vascular events than with incident diabetes. Methods: We related baseline ICAM-1 levels to vascular events (866 CHD and stroke events in 5,685 participants) and incident diabetes (292 in 4,945 without baseline diabetes) in the elderly over 3.2 years of follow-up. R...
Abstract
Cited 55 times since 2008 (3.4 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 6, 18 3 2008, Pages 787-800
Echocardiography in hypertrophic cardiomyopathy: the role of conventional and emerging technologies.
Afonso LC, Bernal J, Bax JJ, Abraham TP
Hypertrophic cardiomyopathy is a relatively common inherited cardiomyopathy that is occasionally challenging to differentiate from hypertensive heart disease and athlete hearts on the basis of morphologic or functional abnormalities alone. Echocardiography has traditionally played a preeminent role in the diagnosis, formulation of management strategies, and the prognostication of this complex disease. In this review, we briefly profile the utility and pitfalls of established echocardiographic mo...
Abstract
Cited 15 times since 2008 (0.9 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 1, Issue 6, 18 3 2008, Pages 729-738
Magnetic resonance cardiac vein imaging: relation to mitral valve annulus and left circumflex coronary artery.
Chiribiri A, Kelle S, Köhler U, Tops LF, Schnackenburg B, Bonamini R, Bax JJ, Fleck E, Nagel E
Objectives: To evaluate in vivo anatomical relationships between the coronary sinus-great cardiac vein (CS-GCV), the mitral valve annulus (MVA), and left circumflex coronary artery (LCX) with cardiovascular magnetic resonance. Background: The CS-GCV has become an anatomical structure of interest because it provides a way of access to the heart for a number of interventional procedures. Previous reports demonstrate that the postulated close anatomical proximity of the CS-GCV to the MVA does not a...
Abstract
Cited 18 times since 2008 (1.1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 11, Issue 1, 11 2 2008, Pages 31-34
Performance and survival of transvenous defibrillation leads: need for a European data registry.
Goette A, Cantu F, van Erven L, Geelen P, Halimi F, Merino JL, Morgan JM, Scientific Initiative Committee of the European Heart Rhythm Association
Although the use of implantable cardioverter defibrillator (ICD) therapy has increased over the last decades, the reporting of ICD lead performance is inadequate. So far, there is neither a European nor worldwide registry on ICD leads. The published long-term results from national or multicentre registries encompass relatively small patient cohorts. Nevertheless, the failure of ICD leads may have substantial clinical consequences, including failure to sense, failure to pace, failure to defibrill...
Abstract
Cited 54 times since 2008 (3.3 per year)
source: EuropePMC
Diabetes care,
Volume 32, Issue 2, 10 2 2008, Pages 308-310
Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population.
Welsh P, Murray HM, Buckley BM, de Craen AJ, Ford I, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Sattar N
Objective: To clarify the association of circulating levels of leptin with risk for cardiovascular disease (CVD) events and new-onset diabetes in men and women. Research design and methods: We related baseline leptin levels to CVD events (n = 864) and incident diabetes (n = 289) in an elderly population (n = 5,672) over 3.2 years of follow-up. Results: In treatment-, age-, and country-adjusted models, leptin was not associated with risk of CVD in men (hazard ratio 1.02 [95% CI 0.90-1.16] per uni...
Abstract
Cited 15 times since 2008 (0.9 per year)
source: EuropePMC
Biochemical and biophysical research communications,
Volume 377, Issue 4, 6 1 2008, Pages 1294-1298
Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.
de Haan W, Out R, Berbée JF, van der Hoogt CC, van Dijk KW, van Berkel TJ, Romijn JA, Jukema JW, Havekes LM, Rensen PC
Apolipoprotein CI (apoCI) has been suggested to influence HDL metabolism by activation of LCAT and inhibition of HL and CETP. However, the effect of apoCI on scavenger receptor BI (SR-BI)-mediated uptake of HDL-cholesteryl esters (CE), as well as the net effect of apoCI on HDL metabolism in vivo is unknown. Therefore, we evaluated the effect of apoCI on the SR-BI-mediated uptake of HDL-CE in vitro and determined the net effect of apoCI on HDL metabolism in mice. Enrichment of HDL with apoCI dose...
Abstract
