9549 results
Cited 4 times since 2012 (0.3 per year)
source: EuropePMC
BMJ case reports,
Volume 2012, 30 5 2012, Pages bcr0120125602
A rare case of portal vein gas: accidental hydrogen peroxide ingestion.
Zengin S, Al B, Genç S, Yarbil P, Yilmaz DA, Gulsen MT
Hydrogen peroxide (H(2)O(2)) is a colourless and odourless liquid with oxidant characteristics used for various purposes. Whereas in lower concentrations (3%), H(2)O(2) is used as a disinfectant in home cleaning products and wound care, in higher concentrations (35%) it is used in textile and paper industry as a bleaching agent and is diluted for use in lightening hair dyes. Like other caustic substances, direct injuries may develop if H(2)O(2) is swallowed and systemic air embolisms may occur d...
Abstract
Cited 26 times since 2012 (1.9 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 43, Issue 3, 30 5 2012, Pages 505-11; discussion 511-2
Transapical aortic valve implantation: mid-term outcome from the SOURCE registry.
Wendler O, Walther T, Schroefel H, Lange R, Treede H, Fusari M, Rubino P, Thomas M, SOURCE investigators
Objectives: Transapical (TA) aortic valve implantation using the Edwards SAPIEN bioprosthesis was commercially introduced in Europe in January 2008. Limited data on the mid-term results are available. Methods: Using data from the SOURCE-Registry (largest consecutive cohort treated using Edwards SAPIEN bioprosthesis in Europe), we report on the mid-term results (≥30 days-2 years) of TA patients. Results: Between November 2007 and December 2009, a total of 1387 patients from 38 European centres un...
Abstract
Cited 6 times since 2012 (0.4 per year)
source: EuropePMC
International wound journal,
Volume 10, Issue 3, 28 4 2012, Pages 348-350
Acute mediastinal bleeding during vacuum-assisted closure.
Vos RJ, Yilmaz A, Sonker U, Kloppenburg GT
Vacuum-assisted closure is commonly used to treat post-sternotomy mediastinitis. Several studies show improved outcome using vacuum-assisted therapy; however, risks using negative pressure should not be underestimated. We describe two cases of acute mediastinal bleeding during vacuum treatment for post-sternotomy mediastinitis and discuss preventative measurements.
Abstract
Cited 22 times since 2012 (1.6 per year)
source: EuropePMC
Resuscitation,
Volume 83, Issue 12, 24 4 2012, Pages 1503-1510
Left ventricular diastolic dysfunction during acute myocardial infarction: effect of mild hypothermia.
Schwarzl M, Huber S, Maechler H, Steendijk P, Seiler S, Truschnig-Wilders M, Nestelberger T, Pieske BM, Post H
Background: Mild hypothermia (MH) decreases infarct size and mortality in experimental reperfused myocardial infarction, but may potentiate ischaemia-induced left ventricular (LV) diastolic dysfunction. Methods: In anaesthetized pigs (70 ± 2 kg), polystyrol microspheres (45 μm) were infused repeatedly into the left circumflex artery until cardiac power output decreased >40%. Then, pigs were assigned to normothermia (NT, 38.0°C, n=8) or MH (33.0°C, n=8, intravascular cooling) and followed for...
Abstract
Cited 32 times since 2012 (2.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 32, Issue 8, 24 4 2012, Pages e72-80
Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.
Karper JC, Ewing MM, Habets KL, de Vries MR, Peters EA, van Oeveren-Rietdijk AM, de Boer HC, Hamming JF, Kuiper J, Kandimalla ER, La Monica N, Jukema JW, Quax PH
Objective: The role of toll-like receptors (TLRs) in vascular remodeling is well established. However, the involvement of the endosomal TLRs is unknown. Here, we study the effect of combined blocking of TLR7 and TLR9 on postinterventional remodeling and accelerated atherosclerosis. Methods and results: In hypercholesterolemic apolipoprotein E*3-Leiden mice, femoral artery cuff placement led to strong increase of TLR7 and TLR9 presence demonstrated by immunohistochemistry. Blocking TLR7/9 with a...
Abstract
Cited 31 times since 2012 (2.3 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 92, Issue 1, 23 4 2012, Pages 62-67
Effects of CYP induction by rifampicin on tamoxifen exposure.
Binkhorst L, van Gelder T, Loos WJ, de Jongh FE, Hamberg P, Moghaddam-Helmantel IM, de Jonge E, Jager A, Seynaeve C, van Schaik RH, Verweij J, Mathijssen RH
Tamoxifen undergoes biotransformation into several metabolites, including endoxifen. Differences in metabolism contribute to the interindividual variability in endoxifen concentrations, potentially affecting treatment efficacy. We evaluated the effects of cytochrome P450 (CYP) induction by rifampicin on the exposure levels of tamoxifen and its metabolites and found that coadministration of rifampicin resulted in markedly reduced (up to 86%, P ≤ 0.040) concentrations of tamoxifen and its metaboli...
Abstract
Cited 26 times since 2012 (1.9 per year)
source: EuropePMC
Diabetes & vascular disease research,
Volume 10, Issue 2, 23 4 2012, Pages 123-134
Non-invasive assessment of microcirculation by sidestream dark field imaging as a marker of coronary artery disease in diabetes.
Djaberi R, Schuijf JD, de Koning EJ, Wijewickrama DC, Pereira AM, Smit JW, Kroft LJ, Roos Ad, Bax JJ, Rabelink TJ, Jukema JW
Purpose: In diabetes, generalised microvascular disease and coronary artery disease (CAD) are likely to occur in parallel. We used a sidestream dark field (SDF) handheld imaging device to determine the relation between the labial microcirculation parameters and CAD in asymptomatic patients with diabetes. Methods: SDF imaging was validated for assessment of labial capillary density and tortuosity. Thereafter, mean labial capillary density and tortuosity were evaluated and compared in non-diabetic...
Abstract
Cited 33 times since 2012 (2.4 per year)
source: EuropePMC
Molecular genetics and metabolism,
Volume 107, Issue 1-2, 22 4 2012, Pages 213-221
Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis.
Hu J, Lu JY, Wong AM, Hynan LS, Birnbaum SG, Yilmaz DS, Streit BM, Lenartowicz EM, Thompson TC, Cooper JD, Hofmann SL
PPT1-related neuronal ceroid lipofuscinosis (NCL) is a lysosomal storage disorder caused by deficiency in a soluble lysosomal enzyme, palmitoyl-protein thioesterase-1 (PPT1). Enzyme replacement therapy (ERT) has not been previously examined in a preclinical animal model. Homozygous PPT1 knockout mice reproduce the known features of the disease, developing signs of motor dysfunction at 5 months of age and death by around 8 months. In the current study, PPT1 knockout mice were treated with purifie...
Abstract
Cited 17 times since 2012 (1.3 per year)
source: EuropePMC
Bulletin of mathematical biology,
Volume 74, Issue 8, 19 3 2012, Pages 1691-1705
Modeling non-inherited antibiotic resistance.
Bootsma MC, van der Horst MA, Guryeva T, ter Kuile BH, Diekmann O
A mathematical model is presented for the increase and decrease of non-inherited antibiotic resistance levels in bacteria. The model is applied to experimental data on E. coli exposed to amoxicillin or tetracyclin in different concentrations. The parameters of the model are estimated using a Monte Carlo Markov Chain method. The model accurately describes build-up and decline of antibiotic resistance caused by physiological adaptations as long as no genetic changes have occurred. The main conclus...
Abstract
Cited 3255 times since 2012 (240.4 per year)
source: EuropePMC
European heart journal,
Volume 33, Issue 14, 19 3 2012, Pages 1787-1847
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC.
McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Køber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Rønnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A, ESC Committee for Practice Guidelines
Abstract
European heart journal,
Volume 33, Issue 22, 18 3 2012, Pages 2882
Completely occluded aorta associated with coronary heart disease.
Montero Cabezas JM, Jurado Roman A, Alonso AR
Abstract
Cited 11 times since 2012 (0.8 per year)
source: EuropePMC
Neuro-oncology,
Volume 14, Issue 7, 15 3 2012, Pages 841-848
Three sensitive assays do not provide evidence for circulating HuD-specific T cells in the blood of patients with paraneoplastic neurological syndromes with anti-Hu antibodies.
de Jongste AH, de Graaf MT, Martinuzzi E, van den Broek PD, Kraan J, Lamers CH, Mallone R, Gratama JW, Sillevis Smitt PA
Anti-Hu antibody-associated paraneoplastic neurological syndromes (Hu-PNSs) are severe and often precede the detection of a malignancy, usually small-cell lung cancer. In Hu-PNS, it is hypothesized that neuronal cells are destroyed by T cells targeted against HuD, a protein expressed by small-cell lung cancer cells and neurons. There is only limited evidence for the existence of HuD-specific T cells. To detect these T cells in the blood of Hu-PNS patients, we employed 3 highly sensitive assays t...
Abstract
Cited 659 times since 2012 (48.6 per year)
source: EuropePMC
Nature genetics,
Volume 44, Issue 6, 13 2 2012, Pages 659-669
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G,
Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the understanding of the genetic basis of insulin resistance. We hypothesized that genes implicated in insulin resistance pathways might be uncovered by accounting for differences in body mass index (BMI) and potential interactions between BMI and genetic variants. We applied a joint meta-analysis approach to test associations w...
Abstract
Cited 12 times since 2012 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 29, Issue 1, 11 2 2012, Pages 221-228
Non-invasive computed tomography coronary angiography as a gatekeeper for invasive coronary angiography.
de Graaf FR, van Velzen JE, de Boer SM, van Werkhoven JM, Kroft LJ, de Roos A, Sieders A, de Grooth GJ, Jukema JW, Schuijf JD, Bax JJ, Schalij MJ, van der Wall EE
To determine the rate of subsequent invasive coronary angiography (ICA) and revascularization in relation to computed tomography coronary angiography (CTA) results. In addition, independent determinants of subsequent ICA and revascularization were evaluated. CTA studies were performed using a 64-row (n = 413) or 320-row (n = 224) multidetector scanner. The presence and severity of CAD were determined on CTA. Following CTA, patients were followed up for 1 year for the occurrence of ICA and revasc...
Abstract
Cited 12 times since 2012 (0.9 per year)
source: EuropePMC
European journal of obstetrics, gynecology, and reproductive biology,
Volume 163, Issue 2, 11 2 2012, Pages 134-141
Perinatal risk-indicators for long-term respiratory morbidity among preterm or very low birth weight neonates.
Teune MJ, van Wassenaer AG, van Buuren S, Mol BW, Opmeer BC, Dutch POPS Collaborative Study Group
Objectives: To develop prediction models for long-term respiratory morbidity. To explore if respiratory distress syndrome (RDS) is a risk-indicator for long-term respiratory morbidity and to identify other perinatal risk-indicators for long-term respiratory morbidity. Study design: In the Dutch POPS cohort 1338 live born infants delivered in The Netherlands in 1983, either before 32 completed weeks gestation and/or with a birth weight below 1500 g, were followed prospectively. We used multivaria...
Abstract
Cited 90 times since 2012 (6.6 per year)
source: EuropePMC
Journal of human evolution,
Volume 63, Issue 1, 10 2 2012, Pages 52-63
Allomaternal care, life history and brain size evolution in mammals.
Isler K, van Schaik CP
Humans stand out among the apes by having both an extremely large brain and a relatively high reproductive output, which has been proposed to be a consequence of cooperative breeding. Here, we test for general correlates of allomaternal care in a broad sample of 445 mammal species, by examining life history traits, brain size, and different helping behaviors, such as provisioning, carrying, huddling or protecting the offspring and the mother. As predicted from an energetic-cost perspective, a po...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
The Lancet. Neurology,
Volume 11, Issue 6, 10 2 2012, Pages 478-479
First-line treatment for CIDP: a new piece of the puzzle.
van Schaik IN
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 42, Issue 1, 10 2 2012, Pages 31-32
Reoperations after paediatric Ross operation.
Hazekamp MG
Abstract
Cited 28 times since 2012 (2.1 per year)
source: EuropePMC
International journal of nephrology,
Volume 2012, 9 2 2012, Pages 963504
Left ventricular diastolic dysfunction in dialysis patients assessed by novel speckle tracking strain rate analysis: prevalence and determinants.
de Bie MK, Ajmone Marsan N, Gaasbeek A, Bax JJ, Groeneveld M, Gabreels BA, Delgado V, Rabelink TJ, Schalij MJ, Jukema JW
Background. Diastolic dysfunction is common among dialysis patients and is associated with increased morbidity and mortality. Novel echocardiographic speckle tracking strain analysis permits accurate assessment of left ventricular diastolic function, independent of loading conditions and taking all myocardial segments into account. The aim of the study was to evaluate the prevalence of diastolic dysfunction in chronic dialysis patients using this novel technique, and to identify its determinants...
Abstract
Cited 53 times since 2012 (3.9 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 5, 7 1 2012, Pages e36180
Call cultures in orang-utans?
Wich SA, Krützen M, Lameira AR, Nater A, Arora N, Bastian ML, Meulman E, Morrogh-Bernard HC, Atmoko SS, Pamungkas J, Perwitasari-Farajallah D, Hardus ME, van Noordwijk M, van Schaik CP
Background: Several studies suggested great ape cultures, arguing that human cumulative culture presumably evolved from such a foundation. These focused on conspicuous behaviours, and showed rich geographic variation, which could not be attributed to known ecological or genetic differences. Although geographic variation within call types (accents) has previously been reported for orang-utans and other primate species, we examine geographic variation in the presence/absence of discrete call types...
Abstract
