9549 results
Cited 2 times since 2012 (0.1 per year)
source: EuropePMC
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology,
Volume 12, Issue 5, 7 1 2012, Pages 406-412
[Effects of radiation emitted from mobile phones on short- term heart rate variability parameters].
Yıldız M, Yılmaz D, Güler I, Akgüllü C
Objective: In this study, the effects of radiation emitted from mobile phone (MP) on heart rate variability (HRV) which is accepted a non-invasive indicator of autonomic nervous system (ANS) were investigated with considering the deficiency of previous studies. Methods: A randomized controlled study has been designed and utilized with 30 young and healthy volunteers. During the experiment that had three periods, the electrocardiogram (ECG) and respiration signals were recorded and MP was attache...
Abstract
Cited 7 times since 2012 (0.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 13, Issue 12, 7 1 2012, Pages 1041-1046
Temporal evolution of left ventricular dyssynchrony after myocardial infarction: relation with changes in left ventricular systolic function.
Nucifora G, Bertini M, Ajmone Marsan N, Scholte AJ, Siebelink HM, Holman ER, Schalij MJ, van der Wall EE, Bax JJ, Delgado V
Aims: The relationship between temporal changes in left ventricular (LV) dyssynchrony and LV functional recovery after acute myocardial infarction (MI) remains unclear. Accordingly, the aim of the present study was to evaluate the temporal evolution of LV synchronicity after acute MI, and to explore the relationship between changes in LV systolic function and LV synchronicity. Methods and results: In 193 patients with a first acute MI, LV dyssynchrony (SDI) and global systolic function were eval...
Abstract
Cited 58 times since 2012 (4.3 per year)
source: EuropePMC
Trials,
Volume 13, 6 1 2012, Pages 54
Open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery ERAS® programme (ORANGE II-trial): study protocol for a randomised controlled trial.
van Dam RM, Wong-Lun-Hing EM, van Breukelen GJ, Stoot JH, van der Vorst JR, Bemelmans MH, Olde Damink SW, Lassen K, Dejong CH, ORANGE II Study Group
Background: The use of lLaparoscopic liver resection in terms of time to functional recovery, length of hospital stay (LOS), long-term abdominal wall hernias, costs and quality of life (QOL) has never been studied in a randomised controlled trial. Therefore, this is the subject of the international multicentre randomised controlled ORANGE II trial. Methods: Patients eligible for left lateral sectionectomy (LLS) of the liver will be recruited and randomised at the outpatient clinic. All randomise...
Abstract
Cited 31 times since 2012 (2.3 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 5, 4 1 2012, Pages e36115
Myocardial structural alteration and systolic dysfunction in preclinical hypertrophic cardiomyopathy mutation carriers.
Yiu KH, Atsma DE, Delgado V, Ng AC, Witkowski TG, Ewe SH, Auger D, Holman ER, van Mil AM, Breuning MH, Tse HF, Bax JJ, Schalij MJ, Marsan NA
Background: To evaluate the presence of myocardial structural alterations and subtle myocardial dysfunction during familial screening in asymptomatic mutation carriers without hypertrophic cardiomyopathy (HCM) phenotype. Methods and findings: Sixteen HCM families with pathogenic mutation were studied and 46 patients with phenotype expression (Mut+/Phen+) and 47 patients without phenotype expression (Mut+/Phen-) were observed. Twenty-five control subjects, matched with the Mut+/Phen- group, were...
Abstract
Cited 58 times since 2012 (4.3 per year)
source: EuropePMC
American journal of respiratory and critical care medicine,
Volume 186, Issue 2, 3 1 2012, Pages 181-189
Left ventricular dysfunction induced by nonsevere idiopathic pulmonary arterial hypertension: a pressure-volume relationship study.
Kasner M, Westermann D, Steendijk P, Dröse S, Poller W, Schultheiss HP, Tschöpe C
Rationale: Severe increase in right ventricular pressure can compromise left ventricular (LV) function because of impaired interventricular interaction and aggravate the symptoms. Objectives: To elucidate how nonsevere idiopathic pulmonary arterial hypertension (IPAH) influences LV function because of impaired interventricular interaction. Methods: Invasive pressure-volume (PV) loop analysis obtained by conductance catheterization was performed at rest and during atrial pacing in patients with m...
Abstract
Cited 2 times since 2012 (0.1 per year)
source: EuropePMC
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis,
Volume 19, Issue 5, 3 1 2012, Pages 535-540
Long-term ongoing coagulopathy in premature infants with respiratory distress syndrome.
Buyukinan M, Yilmaz D, Yalaz M, Koroglu OA, Akisu M, Kavakli K, Kultursay N
The previously reported activated intravascular coagulation system in the acute phase of respiratory distress syndrome (RDS) has not been evaluated in the long term. We assessed the activities of coagulation system of a cohort of premature infants with RDS in comparison with healthy premature infants (HPIs), healthy mature infants (HMIs), and pediatric laboratory controls over a 6-month period. Cord and venous blood samples were taken at birth, at the first month and sixth month. Protein C (PC),...
Abstract
Cited 9 times since 2012 (0.7 per year)
source: EuropePMC
American journal of physical anthropology,
Volume 149, Issue 1, 3 1 2012, Pages 18-25
A model for the evolution of developmental arrest in male orangutans.
Pradhan GR, van Noordwijk MA, van Schaik C
Male Sumatran orangutans (Pongo abelii) may delay for many years the acquisition of the full array of secondary sexual traits, including their characteristic cheek flanges. Such flexible developmental arrest is unique among male primates. Among male Bornean orangutans (Pongo pygmaeus) such long delays appear less common. Here, we develop a simple model to identify the conditions under which developmental arrest can be adaptive. We show that the baseline strategy (i.e., males are not susceptible...
Abstract
Cited 39 times since 2012 (2.9 per year)
source: EuropePMC
Journal of neurology,
Volume 259, Issue 12, 3 1 2012, Pages 2519-2526
Botulinum toxin as treatment for focal dystonia: a systematic review of the pharmaco-therapeutic and pharmaco-economic value.
Zoons E, Dijkgraaf MG, Dijk JM, van Schaik IN, Tijssen MA
Focal dystonia is a common, invalidating neurologic condition characterized by involuntary, sustained muscle contractions causing twisting movements and abnormal postures in one body part. Currently, botulinum toxin is the treatment of first choice. We performed a systematic review towards the pharmaco-therapeutic and pharmaco-economic value of botulinum toxin as treatment for focal dystonia, which yielded the following results. Botulinum toxin is the most effective treatment for reducing dyston...
Abstract
Cited 244 times since 2012 (18 per year)
source: EuropePMC
Basic research in cardiology,
Volume 107, Issue 4, 3 1 2012, Pages 270
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.
Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA, Sluijter JP
Accumulating evidence indicates that programmed necrosis plays a critical role in cell death during ischemia-reperfusion. Necrostatin-1 (Nec-1), a small molecule capable of inhibiting a key regulator of programmed necrosis (RIP1), was shown to prevent necrotic cell death in experimental models including cardiac ischemia. However, no functional follow-up was performed and the action of Nec-1 remains unclear. Here, we studied whether Nec-1 inhibits RIP1-dependent necrosis and leads to long-term im...
Abstract
Cited 10 times since 2012 (0.7 per year)
source: EuropePMC
Transplantation,
Volume 93, Issue 10, 1 1 2012, Pages e39-40; author reply e41-2
Mycophenolic acid-related anemia and leucopenia in renal transplant recipients are related to genetic polymorphisms in CYP2C8.
Bouamar R, Elens L, Shuker N, van Schaik RH, Weimar W, Hesselink DA, van Gelder T
Abstract
Cited 3 times since 2012 (0.2 per year)
source: EuropePMC
Muscle & nerve,
Volume 45, Issue 5, 1 1 2012, Pages 767-8; author reply 768-9
MRC sum-score in the ICU: good reliability does not necessarily reflect "true reliability".
Vanhoutte EK, Faber CG, Merkies IS, PeriNomS Study Group
Abstract
Cited 23 times since 2012 (1.7 per year)
source: EuropePMC
Journal of interprofessional care,
Volume 26, Issue 3, 1 1 2012, Pages 167-169
Simulation: a panacea for interprofessional learning?
Reeves S, van Schaik S
Abstract
Cited 67 times since 2012 (4.9 per year)
source: EuropePMC
Pharmacogenetics and genomics,
Volume 22, Issue 5, 1 1 2012, Pages 373-380
The new CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients.
Elens L, Bouamar R, Hesselink DA, Haufroid V, van Gelder T, van Schaik RH
Objective: Cyclosporine A (CsA) is a substrate of cytochrome P450 3A4 (CYP3A4). Recently, a newly discovered intron 6 single-nucleotide polymorphism in CYP3A4 (rs35599367 C>T), defining the CYP3A4*22 allele, has been linked to reduced hepatic expression and activity of CYP3A4. In the present study, the clinical impact of this single-nucleotide polymorphism was investigated in a cohort of patients receiving a CsA-based immunosuppressive regimen. Materials and methods: A total of 172 de-novo ki...
Abstract
Cited 11 times since 2012 (0.8 per year)
source: EuropePMC
Current biology : CB,
Volume 22, Issue 10, 1 1 2012, Pages R402-4
Animal culture: chimpanzee conformity?
van Schaik CP
Culture-like phenomena in wild animals have received much attention, but how good is the evidence and how similar are they to human culture? New data on chimpanzees suggest their culture may even have an element of conformity.
Abstract
Cited 24 times since 2012 (1.8 per year)
source: EuropePMC
Journal of dairy science,
Volume 95, Issue 5, 1 1 2012, Pages 2476-2484
Incidence of subclinical mastitis in Dutch dairy heifers in the first 100 days in lactation and associated risk factors.
Santman-Berends IM, Olde Riekerink RG, Sampimon OC, van Schaik G, Lam TJ
Heifer mastitis is a problem and risk factors may differ between heifers and older cows. The aim of this study was to estimate the heifer subclinical mastitis (HSCLM) incidence based on elevated somatic cell count (SCC) in the first 100 d in lactation and the associated risk factors in Dutch dairy herds. In 2008, 173 farmers filled in a questionnaire regarding housing and herd management factors potentially related to udder health. In addition, monthly milk production and SCC data from all cattl...
Abstract
Cited 3 times since 2012 (0.2 per year)
source: EuropePMC
The pharmacogenomics journal,
Volume 13, Issue 4, 1 1 2012, Pages 318-324
Added value of pharmacogenetic testing in predicting statin response: results from the REGRESS trial.
van der Baan FH, Knol MJ, Maitland-van der Zee AH, Regieli JJ, van Iperen EP, Egberts AC, Klungel OH, Grobbee DE, Jukema JW
It was investigated whether pharmacogenetic factors, both as single polymorphism and as gene-gene interactions, have an added value over non-genetic factors in predicting statin response. Five common polymorphisms were selected in apolipoprotein E, angiotensin-converting enzyme, hepatic lipase and toll-like receptor 4. Linear regression models were built and compared on R(2) to estimate the added value of single polymorphisms and gene-gene interactions. The selected polymorphisms and the gene-ge...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 197-201
Potential cardiovascular consequences of switching from atorvastatin to generic simvastatin in the Netherlands.
Liew D, Webb K, Meerding WJ, Buskens E, Jukema JW
Background: The statin authorisation form implemented in the Netherlands in January 2009 has led to significant switching of patients from atorvastatin to generic simvastatin, but often to less than equipotent doses. We sought to assess the potential consequences of this. Methods: A modelling analysis was undertaken using data from a pharmacy database covering the majority of drug prescriptions in the Netherlands. Recent meta-analyses provided data on the dose-specific, lipid-modifying potencies...
Abstract
Cited 29 times since 2012 (2.1 per year)
source: EuropePMC
Clinical science (London, England : 1979),
Volume 122, Issue 9, 1 1 2012, Pages 421-428
Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention study.
Meijer CA, Le Haen PA, van Dijk RA, Hira M, Hamming JF, van Bockel JH, Lindeman JH
Animal studies implicate the AP-1 (activator protein-1) pro-inflammatory pathway as a promising target in the treatment of atherosclerotic disease. It is, however, unclear whether these observations apply to human atherosclerosis. Therefore we evaluated the profile of AP-1 activation through histological analysis and tested the potential benefit of AP-1 inhibition in a clinical trial. AP-1 activation was quantified by phospho-c-Jun nuclear translocation (immunohistochemistry) on a biobank of aor...
Abstract
Cited 30 times since 2012 (2.2 per year)
source: EuropePMC
Pharmacogenomics,
Volume 13, Issue 7, 1 1 2012, Pages 831-840
Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.
Postmus I, Verschuren JJ, de Craen AJ, Slagboom PE, Westendorp RG, Jukema JW, Trompet S
Statins are the most commonly prescribed class of drug worldwide and therapy is highly effective in reducing low-density lipoprotein cholesterol levels and cardiovascular events. However, there is large variability in clinical response to statin treatment. Recent research provides evidence that genetic variation contributes to this variable response to statin treatment. Until recently, pharmacogenetic studies have used mainly candidate gene approaches to investigate these effects. Since candidat...
Abstract
Cited 29 times since 2012 (2.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 98, Issue 9, 1 1 2012, Pages 743-754
Transcatheter aortic valve implantation: implications of multimodality imaging in patient selection, procedural guidance, and outcomes.
Delgado V, Kapadia S, Schalij MJ, Schuijf JD, Tuzcu EM, Bax JJ
Abstract
