9549 results
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 18, Issue 10, 1 1 2010, Pages 464-465
Coronary artery anomalies, detection by dual-source computed tomography angiography.
Vliegen HW
Abstract
Cited 19 times since 2010 (1.3 per year)
source: EuropePMC
American journal of physical anthropology,
Volume 143, Issue 2, 1 1 2010, Pages 175-187
Diet traditions in wild orangutans.
Bastian ML, Zweifel N, Vogel ER, Wich SA, van Schaik CP
This study explores diet differences between two populations of wild Bornean orangutans (Pongo pygmaeus wurmbii) to assess whether a signal of social learning can be detected in the observed patterns. The populations live in close proximity and in similar habitats but are separated by a river barrier that is impassable to orangutans in the study region. We found a 60% between-site difference in diet at the level of plant food items (plant species-organ combinations). We also found that individua...
Abstract
Cited 25 times since 2010 (1.6 per year)
source: EuropePMC
American heart journal,
Volume 160, Issue 4, 1 1 2010, Pages 737-743
Prevalence and characteristics of patients with clinical improvement but not significant left ventricular reverse remodeling after cardiac resynchronization therapy.
Auger D, van Bommel RJ, Bertini M, Delgado V, Ng AC, Ewe SH, Shanks M, Marsan NA, Mooyaart EA, Witkowski T, Poldermans D, Schalij MJ, Bax JJ
Background: Although most patients who improve in clinical status after cardiac resynchronization therapy (CRT) also show a significant left ventricular (LV) reverse remodeling, some patients do not show echocardiographic improvement. The aim of the present study was to evaluate the degree of agreement between clinical and echocardiographic response to CRT in a large cohort of heart failure patients, and to evaluate the characteristics of patients with clinical response but without echocardiogra...
Abstract
Cited 46 times since 2010 (3 per year)
source: EuropePMC
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
Volume 100, Issue 10, 1 1 2010, Pages 671-674
Earlier HIV diagnosis--are mobile services the answer?
van Schaik N, Kranzer K, Wood R, Bekker LG
Objectives: To assess the age and gender differences of clients accessing mobile HIV counselling and testing (HCT) compared with clients accessing facility-based testing, and to determine the difference in HIV prevalence and baseline CD4 counts. Methods: This was a prospective observational cross-sectional study of 3 different HIV testing services in Cape Town. We compared data on age, sex, HIV status and CD4 counts collected between August and December 2008 from a mobile testing service (known...
Abstract
Cited 58 times since 2010 (3.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 56, Issue 18, 1 1 2010, Pages 1486-1492
Follow-up after pulmonary valve replacement in adults with tetralogy of Fallot: association between QRS duration and outcome.
Scherptong RW, Hazekamp MG, Mulder BJ, Wijers O, Swenne CA, van der Wall EE, Schalij MJ, Vliegen HW
Objectives: The aim of this study was to analyze whether QRS duration, before and after pulmonary valve replacement (PVR), is related to long-term outcome in patients with tetralogy of Fallot (TOF). Background: Key factors that determine outcome after PVR in adult TOF patients are largely unknown. Recognition of such factors assists the identification of patients at increased risk of adverse events. Methods: Adults who previously underwent total correction for TOF (n=90; age 31.4±10.3 years) and...
Abstract
Cited 38 times since 2010 (2.5 per year)
source: EuropePMC
Pharmacogenomics,
Volume 11, Issue 10, 1 1 2010, Pages 1367-1375
CYP2C19*2 polymorphism is associated with increased survival in breast cancer patients using tamoxifen.
Ruiter R, Bijl MJ, van Schaik RH, Berns EM, Hofman A, Coebergh JW, van Noord C, Visser LE, Stricker BH
Aims: Variant alleles of the CYP2C19 gene were recently associated with survival in breast cancer patients on tamoxifen therapy. CYP2C19 is one of the enzymes involved in the metabolism of tamoxifen into active metabolites. We investigated the hypothesis that CYP2C19*2 and *3 variants, known for their lack of enzyme activity, are associated with an increased breast cancer mortality rate in patients using tamoxifen. Materials & methods: In the prospective population based Rotterdam study, the...
Abstract
Cited 13 times since 2010 (0.9 per year)
source: EuropePMC
Ultrasound in medicine & biology,
Volume 36, Issue 10, 1 1 2010, Pages 1626-1636
Perfusion CT and US of colorectal cancer liver metastases: a correlative study of two dynamic imaging modalities.
Meijerink MR, van Waesberghe JH, van Schaik C, Boven E, van der Veldt AA, van den Tol P, Meijer S, van Kuijk C
The purpose of this study was to evaluate the correlation between dynamic-contrast-enhanced computed tomography (DCE-CT) and first-pass dynamic-contrast-enhanced ultrasound (DCE-US) of normal appearing liver parenchyma and of colorectal cancer liver metastases. Thirty patients with hepatic metastases from colorectal cancer underwent DCE-CT and DCE-US. To obtain DCE-US reproducibility measurements, double contrast-passages (2 × 2.4 mL SonoVue intravenous) were acquired. From several DCE-US-derive...
Abstract
Cited 15 times since 2010 (1 per year)
source: EuropePMC
Current medical research and opinion,
Volume 26, Issue 11, 29 5 2010, Pages 2589-2597
Lipid goals among patients with diabetes or metabolic syndrome: Lipid Treatment Assessment Project (L-TAP) 2.
Jukema JW, Chiang CW, Ferrières J, Santos RD, Verdejo J, Waters DD, Messig M, Tarasenko L
Objective: This analysis of the Lipid Treatment Assessment Project 2 population compared lipid goal attainment by diabetes and metabolic syndrome status. Research design and methods: Dyslipidaemic patients aged ≥ 20 years on stable lipid lowering therapy had their lipid levels determined once during enrolment at investigation sites in nine countries between September 2006 and April 2007. Achievement of low-density lipoprotein (LDL) cholesterol success, triglycerides < 150 mg/dl (1.7 mmol/l),...
Abstract
Cited 146 times since 2010 (9.6 per year)
source: EuropePMC
European heart journal,
Volume 32, Issue 1, 23 4 2010, Pages 104-114
Head-to-head comparison of contrast-enhanced magnetic resonance imaging and electroanatomical voltage mapping to assess post-infarct scar characteristics in patients with ventricular tachycardias: real-time image integration and reversed registration.
Wijnmaalen AP, van der Geest RJ, van Huls van Taxis CF, Siebelink HM, Kroft LJ, Bax JJ, Reiber JH, Schalij MJ, Zeppenfeld K
Aims: Substrate-based ablation of ventricular tachycardia (VT) relies on electroanatomical voltage mapping (EAVM). Integration of scar information from contrast-enhanced magnetic resonance imaging (CE-MRI) with EAVM may provide supplementary information. This study assessed the relation between electrogram voltages and CE-MRI scar characteristics using real-time integration and reversed registration. Methods and results: Fifteen patients without implantable cardiac defibrillator (14 males, 64 ±...
Abstract
Cited 31 times since 2010 (2 per year)
source: EuropePMC
European heart journal,
Volume 31, Issue 24, 23 4 2010, Pages 3054-3062
Association of intraventricular mechanical dyssynchrony with response to cardiac resynchronization therapy in heart failure patients with a narrow QRS complex.
van Bommel RJ, Tanaka H, Delgado V, Bertini M, Borleffs CJ, Ajmone Marsan N, Holzmeister J, Ruschitzka F, Schalij MJ, Bax JJ, Gorcsan J
Aims: current criteria for cardiac resynchronization therapy (CRT) are restricted to patients with a wide QRS complex (>120 ms). Overall, only 30% of heart failure patients demonstrate a wide QRS complex, leaving the majority of heart failure patients without this treatment option. However, patients with a narrow QRS complex exhibit left ventricular (LV) mechanical dyssynchrony, as assessed with echocardiography. To further elucidate the possible beneficial effect of CRT in heart failure pati...
Abstract
Cited 76 times since 2010 (5 per year)
source: EuropePMC
PLoS computational biology,
Volume 6, Issue 9, 23 4 2010, Pages e1000943
Literature mining for the discovery of hidden connections between drugs, genes and diseases.
Frijters R, van Vugt M, Smeets R, van Schaik R, de Vlieg J, Alkema W
The scientific literature represents a rich source for retrieval of knowledge on associations between biomedical concepts such as genes, diseases and cellular processes. A commonly used method to establish relationships between biomedical concepts from literature is co-occurrence. Apart from its use in knowledge retrieval, the co-occurrence method is also well-suited to discover new, hidden relationships between biomedical concepts following a simple ABC-principle, in which A and C have no direc...
Abstract
Cited 56 times since 2010 (3.7 per year)
source: EuropePMC
Journal of the Royal Society, Interface,
Volume 8, Issue 57, 22 4 2010, Pages 578-584
The nosocomial transmission rate of animal-associated ST398 meticillin-resistant Staphylococcus aureus.
Bootsma MC, Wassenberg MW, Trapman P, Bonten MJ
The global epidemiology of meticillin-resistant Staphylococcus aureus (MRSA) is characterized by different clonal lineages with different epidemiological behaviour. There are pandemic hospital clones (hospital-associated (HA-)MRSA), clones mainly causing community-acquired infections (community-associated (CA-)MRSA, mainly USA300) and an animal-associated clone (ST398) emerging in European and American livestock with subsequent spread to humans. Nosocomial transmission capacities (R(A)) of these...
Abstract
Cited 117 times since 2010 (7.7 per year)
source: EuropePMC
Neurology,
Volume 75, Issue 16, 22 4 2010, Pages 1439-1447
Pain in Guillain-Barre syndrome: a long-term follow-up study.
Ruts L, Drenthen J, Jongen JL, Hop WC, Visser GH, Jacobs BC, van Doorn PA, Dutch GBS Study Group
Background: Pain in Guillain-Barré syndrome (GBS) may be pronounced and is often overlooked. Objectives: To obtain detailed information about pain in GBS and its clinical variants. Methods: This was a prospective cohort study in 156 patients with GBS (including 18 patients with Miller Fisher syndrome [MFS]). We assessed the location, type, and intensity of pain using questionnaires at standard time points during a 1-year follow-up. Pain data were compared to other clinical features and serology....
Abstract
Cited 10 times since 2010 (0.7 per year)
source: EuropePMC
Journal of pharmaceutical and biomedical analysis,
Volume 54, Issue 2, 21 3 2010, Pages 387-394
Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry.
Loos WJ, de Graan AJ, de Bruijn P, van Schaik RH, van Fessem MA, Lam MH, Mathijssen RH, Wiemer EA
A rapid and sensitive ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method has been developed and validated for the simultaneous quantitative determination of dextromethorphan (DM) and its metabolites dextrorphan (DX), 3-methoxymorphinan (3MM) and 3-hydroxymorphinan (3HM), in human lithium heparinized plasma. The extraction involved a simple liquid-liquid extraction with 1 ml n-butylchloride from 200μl aliquots of plasma, after the addition of 20 μl 4% (v/v) ammon...
Abstract
Cited 15 times since 2010 (1 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 12, Issue 12, 18 3 2010, Pages 1750-1756
The effect of left ventricular pacing site on cardiac resynchronization therapy outcome and mortality: the results of a PROSPECT substudy.
Mortensen PT, Herre JM, Chung ES, Bax JJ, Gerritse B, Kruijshoop M, Murillo J
Aims: Left ventricular pacing site (LV-PS) was prospectively collected to test the influence of the anatomical LV-PS on the outcome of cardiac resynchronization therapy (CRT) and mortality. Methods and results: Four hundred and twenty-six patients with standard indications for CRT underwent echocardiographic and clinical evaluation before and after CRT implantation. The LV-PS was determined from fluoroscopy using the clockwise principle (CP). The LV-PS was categorized into three prospectively de...
Abstract
Cited 20 times since 2010 (1.3 per year)
source: EuropePMC
American journal of physiology. Heart and circulatory physiology,
Volume 299, Issue 6, 17 3 2010, Pages H2037-45
The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction.
Bongartz LG, Braam B, Verhaar MC, Cramer MJ, Goldschmeding R, Gaillard CA, Steendijk P, Doevendans PA, Joles JA
We recently developed a rat model of cardiorenal failure that is characterized by severe left ventricular systolic dysfunction (LVSD) and low nitric oxide (NO) production that persisted after temporary low-dose NO synthase inhibition. We hypothesized that LVSD was due to continued low NO availability and might be reversed by supplementing NO. Rats underwent a subtotal nephrectomy and were treated with low-dose NO synthase inhibition with N(ω)-nitro-l-arginine up to week 8. After 3 wk of washout,...
Abstract
Cited 16 times since 2010 (1.1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 39, Issue 4, 16 3 2010, Pages 490-494
Risk stratification for adult congenital heart surgery.
van Gameren M, Putman LM, Takkenberg JJ, Bogers AJ
Objective: At this moment, no risk stratification models are available for adult congenital cardiac surgery. This study aims to identify a suitable stratification tool for the adult congenital heart surgery population. Pediatric congenital cardiac surgery score models were therefore tested in an adult congenital population. In addition, an age component was added to these models and performance was compared with the original score systems. Methods: The Risk Adjustment in Congenital Heart Surgery...
Abstract
Cited 19 times since 2010 (1.2 per year)
source: EuropePMC
Veterinary microbiology,
Volume 148, Issue 2-4, 16 3 2010, Pages 183-188
Mortality attributable to bluetongue virus serotype 8 infection in Dutch dairy cows.
Santman-Berends IM, van Schaik G, Bartels CJ, Stegeman JA, Vellema P
In 2007, bluetongue virus serotype 8 (BTV-8) re-emerged in the Netherlands and a large number of farmers notified morbidity and mortality associated with BTV-8 to the authorities. All dead cows in the Netherlands are registered in one of the three age classes: newborn calves 1 year. These registrations result in a complete data set of dead cattle per herd per day from 2003 until 2007. In this study, the mortality associated with BTV-8 for the Dutch dairy industry was estimated, based on this cen...
Abstract
Cited 156 times since 2010 (10.3 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 141, Issue 6, 15 3 2010, Pages 1431-1439
Tricuspid annuloplasty prevents right ventricular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair.
Van de Veire NR, Braun J, Delgado V, Versteegh MI, Dion RA, Klautz RJ, Bax JJ
Objectives: We hypothesize that concomitant tricuspid annuloplasty in patients with tricuspid annular dilatation who undergo mitral valve repair could prevent progression of tricuspid regurgitation and right ventricular remodeling. Methods: In 2002, 80 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performed in 13 patients with grade 3 or 4 tricuspid regurgitation. In 2004, 102 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performe...
Abstract
Cited 38 times since 2010 (2.5 per year)
source: EuropePMC
Breast cancer research and treatment,
Volume 128, Issue 3, 7 1 2010, Pages 679-689
Image-guided tumor resection using real-time near-infrared fluorescence in a syngeneic rat model of primary breast cancer.
Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Que I, Dijkstra J, Kaijzel EL, Prins F, Löwik CW, Smit VT, van de Velde CJ, Vahrmeijer AL
Tumor involvement of resection margins is found in a large proportion of patients who undergo breast-conserving surgery. Near-infrared (NIR) fluorescence imaging is an experimental technique to visualize cancer cells during surgery. To determine the accuracy of real-time NIR fluorescence imaging in obtaining tumor-free resection margins, a protease-activatable NIR fluorescence probe and an intraoperative camera system were used in the EMR86 orthotopic syngeneic breast cancer rat model. Influence...
Abstract
