9549 results
Cited 23 times since 2010 (1.5 per year)
source: EuropePMC
Tissue engineering. Part C, Methods,
Volume 16, Issue 4, 1 1 2010, Pages 597-607
Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study.
Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer JE, Aikawa E
Objectives: Creating functional small-diameter tissue-engineered blood vessels has not been successful to date. Moreover, the processes underlying the in vivo remodeling of these grafts and the fate of cells seeded onto scaffolds remain unclear. Here we addressed these unmet scientific needs by using intravital molecular imaging to monitor the development of tissue-engineered vascular grafts (TEVG) implanted in mouse carotid artery. Methods and results: Green fluorescent protein-labeled human bo...
Abstract
Cited 1 times since 2010 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 18, Issue 7-8, 1 1 2010, Pages 381
Giant pseudoaneurysm after aortic root replacement.
van de Wetering ML, Wagenaar LJ, Bouma BJ, Koolbergen DR
Abstract
Cited 32 times since 2010 (2.1 per year)
source: EuropePMC
International journal of cardiology,
Volume 152, Issue 2, 1 1 2010, Pages 212-217
Mortality in adult congenital heart disease: are national registries reliable for cause of death?
Zomer AC, Uiterwaal CS, van der Velde ET, Tijssen JG, Mariman EC, Verheugt CL, Vaartjes I, Pieper PG, Meijboom FJ, Grobbee DE, Mulder BJ
Background: Statistics on cause-specific mortality are important for prognostic research. The aim of this study was to assess the utility of the national mortality registry in research on causes of death in adult patients with congenital heart disease (CHD). Methods: The CONCOR registry of over 10,000 adults with CHD was used to verify the causes of death provided by the WHO guidelines based national mortality registry, by linkage. Results: Of 7277 patients linked to the national mortality regis...
Abstract
Cited 51 times since 2010 (3.3 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 12, Issue 8, 1 1 2010, Pages 1176-1177
Deactivation of implanted cardioverter-defibrillators at the end of life: results of the EHRA survey.
Marinskis G, van Erven L, EHRA Scientific Initiatives Committee
This survey assesses the current opinion on and practice of the management of terminally ill patients with implanted cardioverter-defibrillators (ICDs) in 47 large European centres. The principal findings of this survey were that most physicians (62%) from European centres who responded to this survey would consider deactivating ICDs at the patient's end of life. In these circumstances, multiple appropriate ICD shocks may be an indication to deactivate an ICD (83% positive answers). Remote...
Abstract
Cited 112 times since 2010 (7.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 3, 1 1 2010, Pages 395-401
Predictors of mitral regurgitation recurrence in patients with heart failure undergoing mitral valve annuloplasty.
Ciarka A, Braun J, Delgado V, Versteegh M, Boersma E, Klautz R, Dion R, Bax JJ, Van de Veire N
Restrictive mitral annuloplasty is a surgical treatment option for patients with heart failure (HF) and functional mitral regurgitation (MR). However, recurrent MR has been reported at mid-term follow-up. The aim of the present study was to identify the echocardiographic predictors of recurrent MR in patients with HF undergoing mitral annuloplasty. During a mean follow-up of 2.6 +/- 1.6 years, 109 patients with HF (49% ischemic and 51% idiopathic dilated cardiomyopathy) who had undergone mitral...
Abstract
Cited 51 times since 2010 (3.3 per year)
source: EuropePMC
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology,
Volume 17, Issue 4, 1 1 2010, Pages 455-461
KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study.
Iakoubova OA, Robertson M, Tong CH, Rowland CM, Catanese JJ, Blauw GJ, Jukema JW, Murphy MB, Devlin JJ, Ford I, Shepherd J
Background: Statin therapy has been found to substantially and significantly reduce coronary events in carriers of the KIF6 719Arg variant (rs20455) but not in noncarriers. We investigated whether, among the elderly, statin therapy also significantly reduced coronary events in carriers but not in noncarriers. Design and methods: Among 5,752 patients of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) study, we assessed the effect of pravastatin, compared with placebo, on cor...
Abstract
Cited 10 times since 2010 (0.7 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 56, Issue 10, 1 1 2010, Pages 754-762
Critical appraisal of the use of cardiac resynchronization therapy beyond current guidelines.
Van Bommel RJ, Delgado V, Schalij MJ, Bax JJ
Cardiac resynchronization therapy (CRT) is an effective treatment for patients with drug-refractory, chronic heart failure. Multiple single-center and multicenter studies have shown significant reductions in left ventricular (LV) volumes and an increase in LV systolic function. More importantly, CRT reduces mortality and morbidity during long-term follow-up. Current guidelines consider CRT as a Class I indication for heart failure patients in New York Heart Association (NYHA) functional class II...
Abstract
Cited 27 times since 2010 (1.8 per year)
source: EuropePMC
Molecular imaging,
Volume 9, Issue 4, 1 1 2010, Pages 223-231
Novel intraoperative near-infrared fluorescence camera system for optical image-guided cancer surgery.
Mieog JS, Vahrmeijer AL, Hutteman M, van der Vorst JR, Drijfhout van Hooff M, Dijkstra J, Kuppen PJ, Keijzer R, Kaijzel EL, Que I, van de Velde CJ, Löwik CW
Current methods of intraoperative tumor margin detection using palpation and visual inspection frequently result in incomplete resections, which is an important problem in surgical oncology. Therefore, real-time visualization of cancer cells is needed to increase the number of patients with a complete tumor resection. For this purpose, near-infrared fluorescence (NIRF) imaging is a promising technique. Here we describe a novel, handheld, intraoperative NIRF camera system equipped with a 690 nm l...
Abstract
Cited 79 times since 2010 (5.2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 96, Issue 16, 1 1 2010, Pages 1275-1280
Beneficial effects of catheter ablation on left ventricular and right ventricular function in patients with frequent premature ventricular contractions and preserved ejection fraction.
Wijnmaalen AP, Delgado V, Schalij MJ, van Huls van Taxis CF, Holman ER, Bax JJ, Zeppenfeld K
Background: Improvement of left ventricular ejection fraction (LVEF) after radiofrequency catheter ablation (RFCA) of frequent premature ventricular contractions (PVCs) has been reported. However, most patients with frequent PVCs have a normal LVEF. In these patients subtle and early forms of PVC-induced left and right ventricular (RV) impairment may not be detected by standard echocardiographic techniques. Objective: To assess the effect of frequent PVCs on ventricular function in patients with...
Abstract
Cited 4 times since 2010 (0.3 per year)
source: EuropePMC
Minerva medica,
Volume 101, Issue 4, 1 1 2010, Pages 255-270
Young at heart. An update on cardiac regeneration.
Smits AM, Ramkisoensing AA, Atsma DE, Goumans MJ
Cardiovascular disease remains one of the most important causes of mortality. Over the past decades important advances have been made in prevention and treatment of acute complications after myocardial infarction (MI). As a result, the number of patients that acutely die from MI has been reduced. Current treatments can not prevent the loss of cardiac contractility caused by cardiomyocyte death, and therefore patients that do survive MI are prone to develop progressive impaired cardiac function,...
Abstract
Cited 45 times since 2010 (2.9 per year)
source: EuropePMC
Magnetic resonance in medicine,
Volume 64, Issue 2, 1 1 2010, Pages 586-594
Automated segmentation of myocardial scar in late enhancement MRI using combined intensity and spatial information.
Tao Q, Milles J, Zeppenfeld K, Lamb HJ, Bax JJ, Reiber JH, van der Geest RJ
Accurate assessment of the size and distribution of a myocardial infarction (MI) from late gadolinium enhancement (LGE) MRI is of significant prognostic value for postinfarction patients. In this paper, an automatic MI identification method combining both intensity and spatial information is presented in a clear framework of (i) initialization, (ii) false acceptance removal, and (iii) false rejection removal. The method was validated on LGE MR images of 20 chronic postinfarction patients, using...
Abstract
Cited 30 times since 2010 (2 per year)
source: EuropePMC
Learning & behavior,
Volume 38, Issue 3, 1 1 2010, Pages 187-194
Social learning research outside the laboratory: How and why?
Kendal RL, Galef BG, van Schaik CP
Abstract
Cited 46 times since 2010 (3 per year)
source: EuropePMC
Neurogenetics,
Volume 12, Issue 1, 1 1 2010, Pages 79-82
OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users.
Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH
Substrates for the Organic Cation Transporter 1, encoded by the SLC22A1 gene, are metformin, amantadine, pramipexole, and, possibly, levodopa. Recently, we identified that the rs622342 A > C polymorphism is associated with the HbA1c lowering effect in metformin users. In the Rotterdam Study, we associated this polymorphism with higher prescribed doses of all anti-Parkinsonian drugs. Between the first and fifth prescriptions for levodopa, for each minor rs622342 C allele, the prescribed doses...
Abstract
Cited 25 times since 2010 (1.6 per year)
source: EuropePMC
Muscle & nerve,
Volume 42, Issue 2, 1 1 2010, Pages 239-244
Monitoring disease progression using high-density motor unit number estimation in amyotrophic lateral sclerosis.
van Dijk JP, Schelhaas HJ, Van Schaik IN, Janssen HM, Stegeman DF, Zwarts MJ
In amyotrophic lateral sclerosis (ALS), progressive motor neuron loss causes severe weakness. Functional measurements tend to underestimate the underlying pathology because of collateral reinnervation. A more direct marker of lower motor neuron loss is of significant importance. We evaluated high-density motor unit number estimation (MUNE), as compared with the ALS Functional Rating Scale (ALSFRS) and maximal compound muscle action potential (CMAP) amplitude, for monitoring and classifying disea...
Abstract
Cited 20 times since 2010 (1.3 per year)
source: EuropePMC
Steroids,
Volume 75, Issue 12, 31 5 2010, Pages 1024-1032
Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.
Siemes C, Visser LE, de Jong FH, Coebergh JW, Uitterlinden AG, Hofman A, Stricker BH, van Schaik RH
Purpose: To study if polymorphisms in genes encoding for CYP3A enzymes, that play a role in steroid hormone metabolism, affect steroid hormone serum levels and prostate cancer incidence or mortality. Methods: 3048 male participants of The Rotterdam Study were included. Prostate cancer cases and non-cases were studied for differences in baseline hormone levels with Student's t-test. General linear models were performed on different random subsets of hormone levels to study associations with...
Abstract
Cited 2 times since 2010 (0.1 per year)
source: EuropePMC
Journal of neurosurgery,
Volume 114, Issue 2, 30 5 2010, Pages 478-484
Effects of sodium selenite and amiloride on calvarial calcification in closing small cranial defects.
Yılmaz DM, Hacıyakupoğlu E, Hacıyakupoğlu S, Polat S, Ozgür H, Sencar L, Dağlıoğlu K
Object: Fresh autogenous bone graft is the most preferred osteoplastic material, whether the purpose is cosmetic, psychological, or for the protection of the brain. These grafts are not rejected and do not react immunologically. The aim of this study was to evaluate the efficacy of autogenous fat rolled with bone dust derived from the bur hole in closing small cranial defects. Additionally, the authors examined the morphological and biochemical effects of Na selenite and amiloride on calvarial c...
Abstract
Cited 24 times since 2010 (1.6 per year)
source: EuropePMC
Journal of neurology, neurosurgery, and psychiatry,
Volume 81, Issue 12, 28 4 2010, Pages 1341-1344
Human chorionic gonadotropin treatment of anti-Hu-associated paraneoplastic neurological syndromes.
van Broekhoven F, de Graaf MT, Bromberg JE, Hooijkaas H, van den Bent MJ, de Beukelaar JW, Khan NA, Gratama JW, van der Geest JN, Frens M, Benner R, Sillevis Smitt PA
Objective: Paraneoplastic neurological syndromes associated with anti-Hu antibodies (Hu-PNS) are mediated by a T-cell immune response that is directed against the Hu antigens. In pregnancy, many Th1-mediated autoimmune diseases such as rheumatoid arthritis and multiple sclerosis regress. We hypothesised that this decreased disease activity during pregnancy may be related to high human chorionic gonadotropin (hCG) levels. Methods: 15 Hu-PNS patients were treated in a prospective, uncontrolled and...
Abstract
Cited 11 times since 2010 (0.7 per year)
source: EuropePMC
European journal of trauma and emergency surgery : official publication of the European Trauma Society,
Volume 36, Issue 6, 27 4 2010, Pages 579-585
Appendicular tuberculosis: review of 155 published cases and a report of two cases.
Akbulut S, Yagmur Y, Bakir S, Sogutcu N, Yilmaz D, Senol A, Bahadir MV
Purpose: This paper provides an overview of the literature on appendicular tuberculosis (ATB) between 1909 and 2010. Methods: We present two cases of primary ATB and a literature review of studies on ATB published in English and accessed via the Pubmed and Google Scholar databases. Results: One hundred fifty-five published cases of ATB were reviewed, and two patients with primary ATB, treated and followed in our clinic, were reported. The age range of the patients (62 females, 60 males and 33 wi...
Abstract
Cited 13 times since 2010 (0.8 per year)
source: EuropePMC
The EPMA journal,
Volume 1, Issue 3, 25 4 2010, Pages 495-502
Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?
Del Re M, Di Paolo A, van Schaik RH, Bocci G, Simi P, Falcone A, Danesi R
Fluoropyrimidines, including 5-fluorouracil (5-FU), are widely used in the treatment of solid tumors and remain the backbone of many combination regimens. Despite their clinical benefit, fluoropyrimidines are associated with gastrointestinal and hematologic toxicities, which often lead to treatment discontinuation. 5-FU undergoes complex metabolism, dihydropyrimidine dehydrogenase (DPD) being the rate-limiting enzyme of inactivation of 5-FU and its prodrugs. Several studies have demonstrated sig...
Abstract
Cited 47 times since 2010 (3.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 106, Issue 5, 23 4 2010, Pages 723-729
Relation of left ventricular twist and global strain with right ventricular dysfunction in patients after operative "correction" of tetralogy of fallot.
van der Hulst AE, Delgado V, Holman ER, Kroft LJ, de Roos A, Hazekamp MG, Blom NA, Bax JJ, Roest AA
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, globa...
Abstract
