9549 results
Nederlands tijdschrift voor geneeskunde,
Volume 149, Issue 48, 1 1 2005, Pages 2655-2658
[The practice guideline 'Heart failure' (first revision) from the Dutch College of General Practitioners; a response from the perspective of cardiology].
Ypenburg C, Schalij MJ, van der Wall EE
The Dutch College of General Practitioners' practice guideline 'Heart failure' provides a clear insight into the history, diagnosis and treatment of patients with chronic heart failure. The revised guideline does however warrant some minor comments. It suggests that an elevated BNP value contributes towards the diagnosis of heart failure, however taking into account the high negative predictive value, BNP should, for the time being at least, only act as an 'instrument of excl...
Abstract
Cited 46 times since 2005 (2.3 per year)
source: EuropePMC
Stem cells (Dayton, Ohio),
Volume 23, Issue 10, 1 1 2005, Pages 1598-1607
Endowing human adenovirus serotype 5 vectors with fiber domains of species B greatly enhances gene transfer into human mesenchymal stem cells.
Knaän-Shanzer S, van de Watering MJ, van der Velde I, Gonçalves MA, Valerio D, de Vries AA
Bone marrow-derived human mesenchymal stem cells (hMSCs) lack the Coxsackie-adenovirus (Ad) receptor and thus are poorly transduced by vectors based on human Ad serotype 5 (Ad5). We investigated whether this problem could be overcome by using tropism-modified Ad5 vectors carrying fiber shaft domains and knobs of different human species B Ads (Ad5FBs). To allow quantitative analyses, these vectors coded for the enhanced green fluorescent protein (eGFP). Transgene expression analysis showed superi...
Abstract
Cited 27 times since 2005 (1.3 per year)
source: EuropePMC
Pediatric cardiology,
Volume 26, Issue 6, 1 1 2005, Pages 756-761
High mortality rate after extubation failure after pediatric cardiac surgery.
Harkel AD, van der Vorst MM, Hazekamp MG, Ottenkamp J
The objective of this study was to evaluate the different causes of extubation failure and the consequent mortality rates in a pediatric population after cardiac surgery. We studied 184 consecutive patients with a median age of 9 months (range, 0-165). In 158 patients, extubation was successful (group A). Nine patients were reintubated for upper airway obstruction and finally extubated successfully (group B). Seventeen patients were reintubated for cardiorespiratory failure, finally leading to d...
Abstract
Cited 116 times since 2005 (5.8 per year)
source: EuropePMC
Atherosclerosis,
Volume 187, Issue 2, 28 4 2005, Pages 415-422
C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003.
Boekholdt SM, Hack CE, Sandhu MS, Luben R, Bingham SA, Wareham NJ, Peters RJ, Jukema JW, Day NE, Kastelein JJ, Khaw KT
Introduction: Measurement of C-reactive protein (CRP) levels has been proposed as a useful marker to improve the prediction of future coronary artery disease (CAD) risk, but this notion has been challenged recently. Methods and results: We performed a prospective case-control study among apparently healthy men and women. The odds ratio (OR) for future CAD incidence was 2.49 (95% CI=2.02-3.08, p for linearity
Abstract
Cited 50 times since 2005 (2.5 per year)
source: EuropePMC
International journal of cardiology,
Volume 111, Issue 3, 27 4 2005, Pages 386-393
Gene expression profiling of human cardiac potassium and sodium channels.
Ordög B, Brutyó E, Puskás LG, Papp JG, Varró A, Szabad J, Boldogkoi Z
Background: The native cardiac ion currents and the action potential itself are the results of the concerted action of several different ion channels. The electrophysiological properties of cardiac cells are determined by the composition of ion channels and by their absolute abundance and proportional ratio. Methods: Our aim in this study was to compare the gene expression level of a representative panel of cardiac ion channels with each other and to compare the same channels in the atrium and v...
Abstract
Cited 11 times since 2005 (0.5 per year)
source: EuropePMC
Radiology,
Volume 237, Issue 3, 26 4 2005, Pages 861-867
Intraatrial repair of transposition of the great arteries: use of MR imaging after exercise to evaluate regional systemic right ventricular function.
Tops LF, Roest AA, Lamb HJ, Vliegen HW, Helbing WA, van der Wall EE, de Roos A
Purpose: To prospectively assess regional systemic right ventricular (RV) function at rest and in response to exercise by using magnetic resonance (MR) imaging in patients who have undergone surgical correction at the atrial level for transposition of the great arteries (TGA). Materials and methods: Informed consent was obtained, and the medical review board approved this study. In 25 adult patients (mean age, 25.8 years +/- 4.7 [standard deviation]; 13 men) who had undergone correction for TGA...
Abstract
Cited 71 times since 2005 (3.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 10, 21 3 2005, Pages 1943-1952
Human adult bone marrow mesenchymal stem cells repair experimental conduction block in rat cardiomyocyte cultures.
Beeres SL, Atsma DE, van der Laarse A, Pijnappels DA, van Tuyn J, Fibbe WE, de Vries AA, Ypey DL, van der Wall EE, Schalij MJ
Objectives: We evaluated whether human adult bone marrow-derived mesenchymal stem cells (hMSCs) could repair an experimentally induced conduction block in cardiomyocyte cultures. Background: Autologous stem cell therapy is a novel treatment option for patients with heart disease. However, detailed electrophysiological characterization of hMSCs is still lacking. Methods: Neonatal rat cardiomyocytes were seeded on multi-electrode arrays. After 48 h, abrasion of a 200- to 450-microm-wide channel ca...
Abstract
Cited 64 times since 2005 (3.2 per year)
source: EuropePMC
European journal of heart failure,
Volume 8, Issue 2, 7 1 2005, Pages 115-121
Diltiazem treatment prevents diastolic heart failure in mice with familial hypertrophic cardiomyopathy.
Westermann D, Knollmann BC, Steendijk P, Rutschow S, Riad A, Pauschinger M, Potter JD, Schultheiss HP, Tschöpe C
Background: The cardiac troponin T I79N mutation, linked to familial hypertrophic cardiomyopathy, carries a high risk of sudden cardiac death even in the absence of significant cardiac hypertrophy. The pathology underlying this mechanism has not yet been identified. Aims: To study the underlying mechanism of this phenomenon we characterized the left ventricular (LV) performance of transgenic mice carrying the human troponin T mutation I79N under basal and isoproterenol-induced stress conditions....
Abstract
Cited 5 times since 2005 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 26, Issue 22, 4 1 2005, Pages 2358-2360
Should the ACC/AHA guidelines be changed in patients undergoing vascular surgery?
Hoeks SE, Bax JJ, Poldermans D
Abstract
Cited 26 times since 2005 (1.3 per year)
source: EuropePMC
The Journal of allergy and clinical immunology,
Volume 116, Issue 5, 3 1 2005, Pages 1007-1013
Adding salmeterol to an inhaled corticosteroid reduces allergen-induced serum IL-5 and peripheral blood eosinophils.
Koopmans JG, Lutter R, Jansen HM, van der Zee JS
Background: Adding a long-acting beta(2)-agonist to inhaled corticosteroids results in better symptomatic asthma control than increasing the dose of inhaled corticosteroids. Objective: Investigating whether adding the long-acting beta(2)-agonist salmeterol to the inhaled corticosteroid fluticasone propionate has an effect on allergen-induced allergic inflammation in asthma. Methods: Bronchial allergen challenges were performed in 26 patients with allergic asthma, pretreating them with a single d...
Abstract
Cited 9 times since 2005 (0.4 per year)
source: EuropePMC
Sexually transmitted diseases,
Volume 32, Issue 10, 1 1 2005, Pages 625-629
Management of Chlamydia cases and their partners: results from a home-based screening program organized by municipal public health services with referral to regular health care.
Götz HM, Hoebe CJ, Van Bergen JE, Veldhuijzen IK, Broer J, De Groot F, Verhooren MJ, Van Schaik DT, Coenen AJ, Richardus JH
Background: We evaluated the management of Chlamydia trachomatis cases and partners found in a systematic home-based chlamydia screening project in the Netherlands among 15- to 29-year-old women and men, organized by the Municipal Public Health Services (MHS). Methods: Infected participants (165/8339 = 2%) were referred to regular curative services. The treating physician provided feedback on treatment and partner notification. Results: Including the effect of a reminder, the treatment rate of a...
Abstract
Cited 53 times since 2005 (2.6 per year)
source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research,
Volume 11, Issue 20, 1 1 2005, Pages 7398-7404
Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
Lepper ER, Baker SD, Permenter M, Ries N, van Schaik RH, Schenk PW, Price DK, Ahn D, Smith NF, Cusatis G, Ingersoll RG, Bates SE, Mathijssen RH, Verweij J, Figg WD, Sparreboom A
Purpose: To evaluate the effect of naturally occurring variants in genes encoding the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in patients with cancer receiving midazolam as a phenotyping probe. Experimental design: Five variants in CYP3A4 and CYP3A5 were evaluated in 58 patients (21 women and 37 men) receiving a short i.v. bolus of midazolam (dose, 0.0145 or 0.025 mg/kg). Midazolam concentrations in plasma were determined using liquid chromatography-mass spectrometry, and pharmacokineti...
Abstract
Cited 24 times since 2005 (1.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 68, Issue 1, 1 1 2005, Pages 136-143
Involvement of furin-like proprotein convertases in the arterial response to injury.
Sluijter JP, Verloop RE, Pulskens WP, Velema E, Grimbergen JM, Quax PH, Goumans MJ, Pasterkamp G, de Kleijn DP
Background: Furin-like proprotein convertases (PCs) are proteolytic activators of proproteins, like membrane type 1-matrix metalloproteinase (MT1-MMP) and transforming growth factor beta (TGF-beta), that are described in the arterial response to injury. However, the involvement of furin-like PCs in the arterial response to injury has not been studied yet. We studied furin, MT1-MMP, MMP levels and TGF-beta signaling after arterial injury. We also investigated the effect of an inhibitor of furin-l...
Abstract
Cited 17 times since 2005 (0.8 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 16, Issue 10, 1 1 2005, Pages 1049-1056
Determinants of recurrent ventricular arrhythmia or death in 300 consecutive patients with ischemic heart disease who experienced aborted sudden death: data from the Leiden out-of-hospital cardiac arrest study.
Kiès P, Boersma E, Bax JJ, van der Burg AE, Bootsma M, van Erven L, van der Wall EE, Schalij MJ
Objective: Evaluation of the relation between clinical characteristics and incidence of recurrent ventricular arrhythmias (VAs) or death during long-term follow-up in a cohort of 300 consecutive ischemic heart disease (IHD) patients who had survived an episode of sudden cardiac arrest (SCA). Background: Survivors of life-threatening VA are at high risk for recurrent events. Methods: A total of 300 consecutive survivors of SCA with IHD were included in a standardized screening and evaluation prot...
Abstract
Cited 5 times since 2005 (0.2 per year)
source: EuropePMC
World journal of gastroenterology,
Volume 11, Issue 38, 1 1 2005, Pages 5997-6002
Effect of herpesvirus infection on pancreatic duct cell secretion.
Hegyi P, Ordog B, Rakonczai Z, Takács T, Lonovics J, Szabolcs A, Sári R, Tóth A, Papp JG, Varró A, Kovács MK, Gray MA, Argent BE, Boldogköi Z
Aim: To examine the effect of acute infection caused by herpesvirus (pseudorabies virus, PRV) on pancreatic ductal secretion. Methods: The virulent Ba-DupGreen (BDG) and non-virulent Ka-RREp0lacgfp (KEG) genetically modified strains of PRV were used in this study and both of them contain the gene for green fluorescent protein (GFP). Small intra/interlobular ducts were infected with BDG virus (10(7) PFU/mL for 6 h) or with KEG virus (10(10) PFU/mL for 6 h), while non-infected ducts were incubated...
Abstract
Cited 124 times since 2005 (6.1 per year)
source: EuropePMC
Heart rhythm,
Volume 2, Issue 10, 1 1 2005, Pages 1076-1081
Fusion of multislice computed tomography imaging with three-dimensional electroanatomic mapping to guide radiofrequency catheter ablation procedures.
Tops LF, Bax JJ, Zeppenfeld K, Jongbloed MR, Lamb HJ, van der Wall EE, Schalij MJ
Background: The outcome of catheter ablation procedures of cardiac arrhythmias depends on the ability to evaluate the underlying mechanism and to depict target sites for ablation. Fusion of different imaging modalities within one system may improve electroanatomic modeling and facilitate ablation procedures. Objectives: The purpose of this study was to study the feasibility of fusion of multislice computed tomography (MSCT) with electroanatomic mapping to guide radiofrequency catheter ablation o...
Abstract
Cited 31 times since 2005 (1.5 per year)
source: EuropePMC
Bone marrow transplantation,
Volume 36, Issue 7, 1 1 2005, Pages 605-610
Long-term renal function after hemopoietic stem cell transplantation in children.
Kist-van Holthe JE, Bresters D, Ahmed-Ousenkova YM, Goedvolk CA, Abbink FC, Wolterbeek R, Bredius RG, Pauwels EK, van der Heijden AJ
Glomerular function of all long-term survivors who underwent hemopoietic stem cell transplantation (HSCT) from 1991 to 1998 (study I, n=121) was studied retrospectively. In addition, we prospectively analyzed glomerular and tubular function of all long-term surviving children who received an HSCT between 1998 and 2000 (study II, n=41). We found a lower prevalence of children with chronic renal failure (CRF) post-HSCT in our more recent cohort (study II: 10%) as compared to the older cohort (stud...
Abstract
Cited 41 times since 2005 (2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 96, Issue 7, 1 1 2005, Pages 996-1001
Role of disease status and type D personality in outcomes in patients with peripheral arterial disease.
Aquarius AE, Denollet J, Hamming JF, De Vries J
Patients with peripheral arterial disease (PAD) often experience diminishing quality of life (QOL) in many domains of their lives. However, factors associated with impaired QOL and perceived stress in these patients are not completely understood. The relative effects of disease status and type D ("distressed") personality (tendencies to experience negative emotions and be socially inhibited) on these patient-based outcomes were examined. It has been argued that type D personality might...
Abstract
Cited 16 times since 2005 (0.8 per year)
source: EuropePMC
The journals of gerontology. Series A, Biological sciences and medical sciences,
Volume 60, Issue 10, 1 1 2005, Pages 1333-1338
Long-term prediction of mortality in elderly persons by dobutamine stress echocardiography.
Biagini E, Elhendy A, Schinkel AF, Rizzello V, Bax JJ, Sozzi FB, Kertai MD, van Domburg RT, Krenning BJ, Branzi A, Rapezzi C, Simoons ML, Poldermans D
Background: Dobutamine stress echocardiography (DSE) was shown to provide incremental prognostic information. However, its role in the prediction of mortality in elderly persons is not well defined. We assessed the value of DSE in the prediction of mortality and hard cardiac events during long-term follow-up in patients older than 65 years. Methods: We studied 1434 patients >65 years old (mean age 72 +/- 3 years) who underwent DSE for evaluation of coronary artery disease. Ischemia was define...
Abstract
Cited 63 times since 2005 (3.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 7, 1 1 2005, Pages 1264-1269
The extent of perfusion-F18-fluorodeoxyglucose positron emission tomography mismatch determines mortality in medically treated patients with chronic ischemic left ventricular dysfunction.
Desideri A, Cortigiani L, Christen AI, Coscarelli S, Gregori D, Zanco P, Komorovsky R, Bax JJ
Objectives: The purpose of this study was to assess the determinants of mortality in a large group of patients with ischemic cardiomyopathy who are treated medically and the impact of the extent of viable tissue on prognosis. Background: Whether the presence of viability drives mortality in patients with ischemic cardiomyopathy who are treated medically and whether the extent of viability is important are issues that are currently unclear. Methods: Two hundred sixty-one patients with ischemic ca...
Abstract
